生物标志物

文档序号:1926582 发布日期:2021-12-03 浏览:7次 >En<

阅读说明:本技术 生物标志物 (Biomarkers ) 是由 A·贝茨 A·伍尔弗森 于 2020-01-17 设计创作,主要内容包括:本发明涉及生物标志物组,用于诊断活动性分枝杆菌感染和/或监测活动性分枝杆菌感染的进展或用于诊断不存在分枝杆菌感染,特别是结核病。这种诊断和/或监测可以是活动性结核病患者与潜伏性、非进展性结核病患者或健康或患病患者之间的鉴别诊断,无论患者是否已经被表征为痰涂片阳性还是痰涂片阴性,和/或无论他们是否被表征为HIV阳性或HIV阴性。以上涉及肺和肺外结核分枝杆菌(Mycobacterium tuberculosis)感染的所有方面,且结核分枝杆菌是结核病的病原体。(The present invention relates to a panel of biomarkers for diagnosing active mycobacterial infection and/or monitoring the progression of active mycobacterial infection or for diagnosing the absence of mycobacterial infection, in particular tuberculosis. Such diagnosis and/or monitoring may be a differential diagnosis between active tuberculosis patients and latent, non-progressive tuberculosis patients or healthy or diseased patients, whether the patients have been characterized as sputum smear positive or negative, and/or whether they have been characterized as HIV positive or HIV negative. The above relates to all aspects of pulmonary and extrapulmonary infection with Mycobacterium tuberculosis (Mycobacterium tuberculosis), and Mycobacterium tuberculosis is the causative agent of tuberculosis.)

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