阅读说明：本技术 羊肚菌菇复合粉及其制备方法 (Morchella esculenta compound powder and preparation method thereof ) 是由 徐嘉贤 周岩伟 朱春江 于 2021-11-05 设计创作，主要内容包括：本发明公开了一种羊肚菌菇复合粉,由以下重量份数的原料制成：羊肚菌15-25、松茸10-30、马勃15-25、桦褐孔菌15-25、桑黄菌15-30。制备方法,包括以下步骤：S1、称取原料：羊肚菌15-25、松茸10-30、马勃15-25、桦褐孔菌15-25、桑黄菌15-30；S2、脱水干燥：将原料各自分拣、清洗后,进行脱水干燥处理；S3、粉碎：将脱水后的原料粉碎为粉末；S5、混合包装：将各种原料粉末混合后,包装。本发明菌菇粉实现了活性成分功效互补、对人体起到综合保健作用、调理人体机能。(The invention discloses morchella esculenta compound powder which is prepared from the following raw materials in parts by weight: 15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius. The preparation method comprises the following steps: s1, weighing the following raw materials: 15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius; s2, dehydrating and drying: sorting and cleaning the raw materials respectively, and then dehydrating and drying the raw materials; s3, crushing: crushing the dehydrated raw materials into powder; s5, mixing and packaging: mixing the above powders, and packaging. The mushroom powder realizes the effect complementation of active ingredients, has comprehensive health care effect on human bodies and regulates the functions of the human bodies.)

1. The morchella esculenta compound powder is characterized by being prepared from the following raw materials in parts by weight: 15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius.

2. The morchella esculenta compound powder according to claim 1, which is prepared from the following raw materials in parts by weight:

20-25 parts of morchella esculenta, 20-25 parts of tricholoma matsutake, 20-25 parts of puffball, 20-25 parts of inonotus obliquus and 20-25 parts of phellinus igniarius.

3. The morchella esculenta compound powder according to claim 2, which is prepared from the following raw materials in parts by weight:

morchella 20, matsutake 20, puffball 20, inonotus obliquus 20 and phellinus igniarius 20.

4. A preparation method of morchella esculenta compound powder is characterized by comprising the following steps:

s1, weighing the following raw materials: 15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius;

s2, dehydrating and drying: sorting and cleaning the raw materials respectively, and then dehydrating and drying the raw materials;

s3, crushing: crushing the dehydrated raw materials into powder;

s5, mixing and packaging: mixing the above powders, and packaging.

5. The preparation method of the morchella mushroom composite powder according to claim 4, wherein in the step S2, the dehydration drying is at least one of low-temperature drying, freeze vacuum drying and air-flow drying.

6. The preparation method of the morchella esculenta compound powder according to claim 5, wherein in the step S2, the water content of the dried raw material is less than 5%.

7. The preparation method of composite Morchella esculenta powder as claimed in claim 4, wherein in the step S3, the pulverization is performed by two-stage pulverization, wherein the primary pulverization is coarse pulverization with a fineness of 800-300 microns, and the secondary pulverization is fine pulverization with a fineness of 200-300 microns.

8. The preparation method of morel mushroom composite powder as claimed in claim 4, wherein in the step S3, the pulverization is performed in a coarse pulverization manner, and the fineness of the raw materials is 300-1000 μm.

Technical Field

The invention relates to fungus powder, in particular to morchella esculenta compound powder and a preparation method thereof.

Background

The mushroom is a common food material, and is a large fungus eaten by edible fungi and human beings. The edible fungi known in China have more than 350 kinds, are delicious and rich in nutrition, and contain rich nutritional ingredients such as protein, carbohydrate, multiple vitamins, multiple amino acids and the like. There are many edible and medicinal fungi, but the edible and medicinal fungi have no function of regulating body functions as medicines.

Disclosure of Invention

The technical problem to be solved by the invention is to provide morchella esculenta compound powder which has complementary active ingredient effects, plays a comprehensive health-care role on a human body and regulates the function of the human body and a preparation method thereof aiming at the defects of the prior art.

The technical scheme adopted by the invention for solving the technical problems is as follows:

the morchella mushroom composite powder is prepared from the following raw materials in parts by weight:

15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius.

Further, the morchella esculenta compound powder is preferably prepared from the following raw materials in parts by weight:

20-25 parts of morchella esculenta, 20-25 parts of tricholoma matsutake, 20-25 parts of puffball, 20-25 parts of inonotus obliquus and 20-25 parts of phellinus igniarius.

Further, the morchella esculenta compound powder is preferably prepared from the following raw materials in parts by weight:

morchella 20, matsutake 20, puffball 20, inonotus obliquus 20 and phellinus igniarius 20.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: 15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius;

s2, dehydrating and drying: sorting and cleaning the raw materials respectively, and then dehydrating and drying the raw materials;

s3, crushing: crushing the dehydrated raw materials into powder;

s5, mixing and packaging: mixing the above powders, and packaging.

Further, in the preparation method of the morel mushroom composite powder, preferably, in the step S2, the dehydration drying is at least one of low-temperature drying, freeze vacuum drying and pneumatic drying.

Further, in the preparation method of the morchella esculenta compound powder, in the step S2, the water content of the dried raw material is preferably less than 5%.

Further, in the preparation method of the morel mushroom composite powder, in the step S3, preferably, the pulverization is a two-stage pulverization, wherein the primary pulverization is a coarse pulverization with a fineness of 800-.

Further, in the preparation method of the morchella esculenta compound powder, in the step S3, the pulverization is preferably performed in a coarse pulverization manner, and the fineness of the raw materials is 300-1000 microns.

The formula of the invention has the following beneficial effects:

the morchella mushroom composite powder is prepared by compounding a plurality of mushroom with medicinal and edible effects, retains active ingredients in the original mushroom, has medicinal functions, compounds the mushroom with a plurality of different ingredients, enables the active ingredients to have complementary effects, and plays a comprehensive health care role for a human body: 1. reducing blood pressure, blood fat and blood sugar; 2. enhancing organism oxidation resistance, improving vascular endothelial function, and enhancing antioxidant activity; 3. antibacterial and anti-inflammatory effects; 4. reducing cholesterol content and blood viscosity, and preventing cardiovascular and cerebrovascular diseases such as hypertension, atherosclerosis and cerebral thrombosis; 5. has antitumor activity; 6. increasing insulin content in vivo, accelerating hepatic glucose metabolism, and reducing postprandial blood sugar content.

In recent years, more than 200 kinds of polysaccharide substances with biological activity are extracted from higher basidiomycetes at home and abroad, nearly 30 kinds of fungal polysaccharides with important economic and medicinal values are found in China, and 15 kinds of fungal polysaccharides with clear chemical structures are found in China. The fungal polysaccharide is one of the main active ingredients of fungal medicaments, can enhance the immune function of a human body, has the functions of resisting tumors, regulating immunity, reducing blood pressure and blood fat, resisting thrombus, invigorating stomach and protecting liver, resisting oxidation, radiation, ulcer, aging, virus, blood sugar and the like. The fungal polysaccharide is mainly used for researching the medicinal value of the fungal polysaccharide at home and abroad, and the research becomes one of the directions for developing new drugs at present.

In the present invention, Morchella esculenta is a wild dual-purpose fungus, and includes fruiting bodies of Morchella esculenta (L.) Pers, Morchella microphylla and gulstic Peck, Morchella conica Pers, Morchella crassipes (Vent.) Pers, Morchella esculenta and Morchella deleiciosa Fr. The morchella contains polysaccharide for inhibiting tumor and active components for resisting bacteria and viruses, and in addition, the selenium contained in the morchella is a component of human erythrocyte glutathione peroxidase, so that a large amount of oxygen molecules can be transported to inhibit malignant tumor and inactivate cancer cells; the antioxidant effect of selenium can change the generation direction of carcinogen, and remove toxic substance by combination, thereby reducing or eliminating carcinogenic risk, and has effects of enhancing immunity, relieving fatigue, resisting virus, inhibiting tumor, etc.

The tricholoma matsutake belongs to basidiomycotina and tricholoma family, is ectotrophic mycorrhizal fungi of trees such as pine oak and the like, has unique and strong fragrance, and is rare and rare natural medicinal fungi in the world. The tricholoma matsutake contains double-chain tricholoma matsutake polysaccharide, tricholoma matsutake polypeptide and unique anticancer substance tricholoma matsutake alcohol (RNA) all over the world, has super strong gene mutation resistance and strong anticancer effect, and is the first of 15 kinds of edible fungi with antitumor activity. The hot water extract (polysaccharide) of the sporophyte has the inhibition rate of 91.8 percent on the mouse sarcoma S-180 and the inhibition rate of 70 percent on the ehrlich ascites carcinoma. In addition, the study shows that the tricholoma matsutake glycoprotein MTSO also has an inhibition effect on human breast cancer (MCF-7) cell lines, and has low toxicity on normal cells. Meanwhile, the tricholoma matsutake polysaccharide can also induce apoptosis of K562 cells and inhibit proliferation of leucocytes, and researches show that when a liver cancer patient takes the tricholoma matsutake after liver cancer resection, the survival rate can be obviously improved, and the GOT, r-GTP and bilirubin values can be obviously reduced.

Tricholoma matsutake has the function of treating diabetes. The main action mode is 1, the content of insulin in vivo is improved, and the tricholoma matsutake can stimulate islet beta cells to secrete insulin, protect and repair the islet beta cells and increase the content of insulin in vivo; 2. the alpha-glucosidase inhibitor is a novel hypoglycemic drug, and experiments prove that the alpha-Glucosidase Inhibitor (GI) extracted from the tricholoma matsutake can reduce the postprandial blood sugar of a diabetic patient, and 3, the tricholoma matsutake can directly reduce the blood sugar, improve the insulin resistance, accelerate the liver glucose metabolism and have the effect of directly reducing the blood sugar.

The content of unsaturated fatty acid in Tricholoma matsutake is far higher than that of saturated fatty acid, wherein the content of oleic acid, linoleic acid and palmitic acid accounts for the specific weight of fatty acid. Oleic acid and linoleic acid can effectively remove garbage in human blood, delay aging, reduce cholesterol content and blood viscosity, and prevent cardiovascular and cerebrovascular diseases such as hypertension, atherosclerosis and cerebral thrombosis.

Lasiosphaera Seu Calvatia (Lycoperdon spp.) is a Lasiosphaera Seu Calvatia medicinal material carried by Basidiomycetes Lasiosphaera Seu Calvatia in 2000 edition, and is a Lasiosphaera Seu Calvatia of Botiaceae, and is derived from three sources, including peeled Lasiosphaera Seu Calvatia, Lasiosphaera Seu Calvatia and purple Lasiosphaera Seu Calvatia. Wherein the fruit body of the peeled puffball contains leucine, tyrosine, urea, ergosterol, lipid, puffball and the like, 72.18% of sodium phosphate, 15.66% of aluminum, 2.93% of magnesium, 0.44% of silicic acid and 8.77% of sulfate, wherein the content of the sodium phosphate is the highest. The desquamation puffball has obvious hemostatic effect on oral cavity hemorrhagic diseases, is not inferior to starch sponge or gelatin sponge, and is also effective on epistaxis. Through in vitro tests, the desquamation puffball decoction has certain inhibition effect on staphylococcus aureus, pseudomonas aeruginosa, proteus vulgaris and pneumococcus, and also has inhibition effect on a few pathogenic fungi.

Lasiosphaera Seu Calvatia (Lasiosphaera Seu Calvatia) fruiting body liposoluble part contains ergosta-7, 22-diene-3-ketone, ergosta-7, 22-diene-3-ol, beta-sitosterol, palmitic acid, peroxidase, coenzyme Q and fatty acid, etc., and has total amino acid content of 32.9mg/100 mg. The Lasiosphaera Seu Calvatia preparation has remarkable anticancer activity by animal test.

Lasiosphaera Seu Calvatia, fruiting body contains lasiocarpic acid as antibacterial component, p-carboxyphenylazoxycyanide as antifungal and antibacterial component, and steroid dimer. In addition, it contains amino acids and phosphates. The Lasiosphaera Seu Calvatia preparation has certain inhibiting effect on bacteria and fungi.

Inonotus obliquus (Inonotus obliquus) is a folk medicine in Soviet Union, Poland, Japan and other countries, and comprises polysaccharides, Inonotus obliquus alcohol, various kinds of oxidation triterpenoids, Inonotus obliquus, streptococcic acid, various kinds of lanosterol triterpenoids, folic acid derivatives, aromatic vanillic acid, syringic acid and gamma-hydroxybenzoic acid, and is also reported to be separated into tannin compounds, steroids, alkaloid compounds, melanin, low-molecular polyphenols and lignin compounds. A glycoprotein (FIS-1) and a water-soluble polysaccharide (F1) have been extracted from sclerotia and hyphae, and have been found to have significant hypoglycemic effects. Especially water-soluble polysaccharide (F1), the inonotus obliquus is administrated at one time with the weight of 50mg/kg, after 3 hours, the blood sugar content of the hyperglycemic mouse is reduced by half and can be maintained for 48 hours; the inonotus obliquus has obvious effect of preventing and treating hypertension. Related documents load that the cure rate of inonotus obliquus fine powder produced by Russia Kansu Mole base pharmaceutical companies on diabetes reaches 93%, and the inonotus obliquus is widely applied to scientific research and clinic of type 2 diabetes.

The beta-D-glucan in the inonotus obliquus has extremely high SOD activity, has obvious inhibiting effect on various tumor cells such as breast cancer, lip cancer, gastric cancer, subaural adenocarcinoma, lung cancer, skin cancer, rectal cancer and Hodgkin lymphoma, not only can effectively improve the capability of eliminating various reactive oxygen radicals of a human body, but also can restore an antioxidant system in the human body, enhance the antioxidant capability of the human body, inhibit the diffusion and recurrence of cancer cells, prevent the absorption of harmful substances such as carcinogenic substances in the stomach and intestine and promote the excretion.

The ethanol extract of Inonotus obliquus can remarkably enhance the activity of catalase, superoxide dismutase (SOD) and glutathione peroxidase. These enzymes reduce malonate levels in diabetic patients while repairing damaged pancreatic tissue. It also has effects in enhancing immunity, improving vascular endothelial function, enhancing antioxidant activity, preventing lipid peroxidation, resisting oxygen free radical injury, regulating gastrointestinal function, inhibiting platelet aggregation, and protecting and repairing damaged liver and kidney tissue. The multiple effects of the pharmacological action are particularly beneficial to preventing and treating the occurrence of the multiple system organ complications caused by the sugar metabolism disorder of the diabetes.

Polysaccharides and triterpenes contained in Inonotus obliquus can effectively activate immune system and inhibit virus proliferation. The recent research proves that the inonotus obliquus also has a certain special physiological active substance and has the function of strengthening cell walls, thereby preventing viruses from releasing enzymes, preventing the viruses from attaching to the cell walls and inhibiting the viruses from propagating and replicating, and therefore, the inonotus obliquus has a good preventive effect on influenza.

The inonotus obliquus can remarkably reduce the blood pressure of large arteries, the blood pressure of small arteries and the blood pressure of capillaries, maintain the normal range, simultaneously protect tissues and organs, and is beneficial to preventing or treating hypertension and complications thereof. The triterpenes in the inonotus obliquus can effectively inhibit angiotensin converting enzyme, regulate blood lipid and improve blood oxygen supply capability. Enhancing brain cell activity, improving memory, preventing thrombosis, and preventing angiosclerosis and apoplexy.

Phellinus linteus is a precious large fungus with important medicinal value, and the use of Phellinus linteus in China has been more than 2000 years from Han dynasty to date. The Phellinus linteus comprises polysaccharides, flavones, triterpenes, nucleosides, sterols, alkaloids, furan derivatives, amino acid polypeptides, fatty acids, inorganic elements, etc.

The research on the fungal polysaccharide in the phellinus igniarius aqueous extract shows that the fungal polysaccharide has a tumor cell proliferation inhibition rate as high as 96.7 percent and has no toxicity on normal cells. Therefore, research on phellinus igniarius is gradually promoted, and the phellinus igniarius is recognized as one of medicinal fungi with the best traditional Chinese medicine effect in the field of biological anticancer at present.

At present, researches on Phellinus linteus show that more than 20 flavonoids extracted and identified from Phellinus linteus are available. Flavonoids have been reported to improve cardiovascular and cerebrovascular circulation, scavenge free radicals in the body, resist aging, inhibit lipid peroxidation, inhibit platelet aggregation, prevent capillary penetration, protect the skin, resist cancer, bacteria, viruses, liver toxicity, allergy and enhance autoimmunity.

Phellinus linteus contains a large amount of triterpenes, and terpenes separated from Phellinus linteus include sesquiterpenes, diterpenes and triterpenes. Triterpenes (Thiterpenoids) are terpenoids consisting of 30 carbon atoms, some in free form and some in the form of glycosides (triterpene glycosides) combined with sugars. The triterpene and triterpene glucoside have wide biological activity, and scientific research shows that the triterpene compound has various pharmacological actions such as hemolysis, blood fat reduction, blood pressure reduction, tumor resistance, cancer resistance, liver protection, HIV-1 and HIV-1 protease activity resistance, anti-inflammation, antibiosis, anti-HIV, contraception and the like.

Detailed Description

In order to more clearly understand the technical features, objects, and effects of the present invention, specific embodiments of the present invention will now be described in detail.

The morchella mushroom composite powder is prepared from the following raw materials in parts by weight:

15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius.

Further, the morchella esculenta compound powder is preferably prepared from the following raw materials in parts by weight:

20-25 parts of morchella esculenta, 20-25 parts of tricholoma matsutake, 20-25 parts of puffball, 20-25 parts of inonotus obliquus and 20-25 parts of phellinus igniarius.

Further, the morchella esculenta compound powder is preferably prepared from the following raw materials in parts by weight:

morchella 20, matsutake 20, puffball 20, inonotus obliquus 20 and phellinus igniarius 20.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: 15-25 parts of morchella esculenta, 10-30 parts of tricholoma matsutake, 15-25 parts of puffball, 15-25 parts of inonotus obliquus and 15-30 parts of phellinus igniarius;

s2, dehydrating and drying: sorting and cleaning the raw materials respectively, and then dehydrating and drying the raw materials;

s3, crushing: crushing the dehydrated raw materials into powder;

s5, mixing and packaging: mixing the above powders, and packaging.

In the processing process, if the raw material is dried at a high temperature, part of active nutrients of the raw material mushrooms are destroyed, and therefore, in the preparation method of the morchella esculenta compound powder, preferably, in the step S2, the dehydration drying is at least one of low-temperature drying, freeze vacuum drying and air flow drying.

In order to pulverize the raw material to a suitable fineness, the moisture content of the dried raw material is less than 5% in step S2.

The crushing requirement is determined according to the finally formed dosage form of the morel mushroom composite powder, the first scheme is to prepare the raw materials into powder with smaller granularity, and preferably in the step S3, the crushing is two-stage crushing, wherein the primary crushing is coarse crushing, the fineness is 1000 microns, and the secondary crushing is fine crushing, the fineness is 300 microns and is 800 microns.

The second scheme is to make the material into powder with common granularity, relatively great fineness span and no further limitation on granularity range. The crushing is carried out in a coarse crushing mode, and the fineness of the raw materials is 300-1000 microns.

The following is described in detail by way of specific examples:

example 1, the morchella esculenta compound powder is prepared from the following raw materials in parts by weight:

morchella 20, matsutake 20, puffball 20, inonotus obliquus 20 and phellinus igniarius 20.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: weighing 20kg of morchella esculenta, 20kg of tricholoma matsutake, 20kg of puffball, 20kg of inonotus obliquus and 20kg of phellinus igniarius in parts by weight;

s2, dehydrating and drying: sorting Morchella, Tricholoma matsutake, Lasiosphaera Seu Calvatia, Inonotus obliquus, and Phellinus igniarius, respectively, selecting impurities, cleaning, and dehydrating and drying; in order to avoid the loss of active ingredients in mushrooms caused by high temperature, a freeze drying method is adopted, and the method specifically comprises the following steps: fresh raw materials are respectively dried in the environment of 50 ℃ below zero through vacuum drying technology, and most of nutrients and active substances of fresh mushrooms can be preserved. And the dried material maintains the original chemical composition and physical properties (such as porous structure, colloidal properties, etc.).

S3, crushing: crushing the dehydrated raw materials into powder; specifically, two-stage crushing is adopted, wherein the coarse powder is firstly crushed and has the fineness of 1000 microns in 800-plus-one mode, and the fine powder is further crushed and has the fineness of 300 microns in 200-plus-one mode.

S5, mixing and packaging: mixing the above powders, and packaging. The crushed raw materials are uniformly mixed, and can be packaged as powder or filled into capsules due to small crushing fineness.

Embodiment 2, the morchella esculenta compound powder is prepared from the following raw materials in parts by weight:

morchella esculenta 15, tricholoma matsutake 10, puffball 15, inonotus obliquus 15 and phellinus igniarius 15.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: weighing 15kg of morchella esculenta, 10kg of tricholoma matsutake, 15kg of puffball, 15kg of inonotus obliquus and 15kg of phellinus igniarius in parts by weight;

s2, dehydrating and drying: sorting Morchella, Tricholoma matsutake, Lasiosphaera Seu Calvatia, Inonotus obliquus, and Phellinus igniarius, respectively, selecting impurities, cleaning, and dehydrating and drying; in order to avoid the loss of active ingredients in mushrooms caused by high temperature, a low-temperature drying method is adopted, and the method specifically comprises the following steps: the fresh raw materials are dried in an oven at the temperature of 50-70 ℃ respectively.

S3, crushing: crushing the dehydrated raw materials into powder; the method specifically adopts primary crushing to obtain coarse powder with the fineness of 300-1000 microns.

S5, mixing and packaging: mixing the above powders, and packaging. Mixing the pulverized materials, and encapsulating.

Embodiment 3, the morchella esculenta compound powder is prepared from the following raw materials in parts by weight:

morchella esculenta 25, matsutake 30, puffball 25, inonotus obliquus 25 and phellinus igniarius 30.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: weighing 25kg of morchella esculenta, 30kg of tricholoma matsutake, 25kg of puffball, 25kg of inonotus obliquus and 30kg of phellinus igniarius in parts by weight of kilograms;

s2, dehydrating and drying: sorting Morchella, Tricholoma matsutake, Lasiosphaera Seu Calvatia, Inonotus obliquus, and Phellinus igniarius, respectively, selecting impurities, cleaning, and dehydrating and drying; in order to avoid the loss of active ingredients in the mushrooms due to high temperature, an air flow drying method is adopted, and the method specifically comprises the following steps: fresh raw materials are respectively dried under the normal temperature environment by an airflow drying technology.

S3, crushing: crushing the dehydrated raw materials into powder; specifically, two-stage crushing is adopted, wherein the coarse powder is firstly crushed and has the fineness of 1000 microns in 800-plus-one mode, and the fine powder is further crushed and has the fineness of 300 microns in 200-plus-one mode.

S5, mixing and packaging: mixing the above powders, and packaging. The crushed raw materials are uniformly mixed, and can be packaged as powder or filled into capsules due to small crushing fineness.

Embodiment 4, the morchella esculenta compound powder is prepared from the following raw materials in parts by weight:

morchella 23, matsutake 27, puffball 25, inonotus obliquus 21 and phellinus igniarius 28.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: weighing 23kg of morchella esculenta, 27kg of tricholoma matsutake, 25kg of puffball, 21kg of inonotus obliquus and 28kg of phellinus igniarius in parts by weight;

s2, dehydrating and drying: sorting Morchella, Tricholoma matsutake, Lasiosphaera Seu Calvatia, Inonotus obliquus, and Phellinus igniarius, respectively, selecting impurities, cleaning, and dehydrating and drying; in order to avoid the loss of active ingredients in the mushrooms due to high temperature, an air flow drying method is adopted, and the method specifically comprises the following steps: fresh raw materials are respectively dried under the normal temperature environment by an airflow drying technology.

S3, crushing: crushing the dehydrated raw materials into powder; specifically, two-stage crushing is adopted, wherein the coarse powder is firstly crushed and has the fineness of 1000 microns in 800-plus-one mode, and the fine powder is further crushed and has the fineness of 300 microns in 200-plus-one mode.

S5, mixing and packaging: mixing the above powders, and packaging. The crushed raw materials are uniformly mixed, and can be packaged as powder or filled into capsules due to small crushing fineness.

Example 5, the morchella esculenta compound powder is prepared from the following raw materials in parts by weight:

morchella 22, matsutake 28, puffball 18, inonotus obliquus 21 and phellinus igniarius 19.

A preparation method of morchella esculenta compound powder comprises the following steps:

s1, weighing the following raw materials: weighing 22kg of morchella esculenta, 28kg of tricholoma matsutake, 18kg of puffball, 21kg of inonotus obliquus and 19kg of phellinus igniarius in parts by weight;

s2, dehydrating and drying: sorting Morchella, Tricholoma matsutake, Lasiosphaera Seu Calvatia, Inonotus obliquus, and Phellinus igniarius, respectively, selecting impurities, cleaning, and dehydrating and drying; in order to avoid the loss of active ingredients in the mushrooms due to high temperature, a freeze vacuum drying method is adopted, and the method specifically comprises the following steps: fresh raw materials are respectively dried by a freezing vacuum drying technology at the temperature of-170 ℃.

S3, crushing: crushing the dehydrated raw materials into powder; specifically, two-stage crushing is adopted, wherein the coarse powder is firstly crushed and has the fineness of 1000 microns in 800-plus-one mode, and the fine powder is further crushed and has the fineness of 300 microns in 200-plus-one mode.

S5, mixing and packaging: mixing the above powders, and packaging. The crushed raw materials are uniformly mixed, and can be packaged as powder or filled into capsules due to small crushing fineness.

And (3) application effect verification:

1. XXX, male, 60 years old, chest pain, palpitation, shortness of breath, dizziness, half a year, and arrhythmia and myocardial ischemia by hospital. The capsules prepared in the embodiment 2 of the invention are taken three times a day in 2019 and twenty capsules each time, and after the capsules are taken, symptoms of chest pain basically disappear in 5 months without palpitation, shortness of breath and dizziness.

2. XX, female, age 34, with pelvic inflammatory disease for decades, antibiotic treatment improved and repeated. The powder prepared in the embodiment 1 of the invention is taken three times a day in 2018 and 25g each time in 10 months, abdominal pain is gradually relieved after the powder is taken for 1 month, the abdominal pain basically disappears after the powder is taken for 2 months, and pelvic inflammation disappears after the powder is checked for 4 months.

3. XXX, male, 52 years old, with a neck pain on the left for one month, hospital examination of a benign single-shot thyroid nodule in the neck of 1.5cm, beginning to take capsules prepared according to example 2 of the present invention 2 in 2 months of 2020 three times a day, twenty capsules each time, four months after taking, the thyroid nodule shrinking to 0.5cm and disappearing half a year later.

4. XXX, male, age 41, often feels weak, tired and sleepy, is susceptible to cold, memory loss, poor appetite, no organic lesions in hospital examination, and is diagnosed as sub-health. After the powder prepared in the embodiment 4 of the invention is taken three times a day, 25g each time, in 4 months of 2020, fatigue and sleepiness symptoms are reduced, appetite is recovered, and sleep is good after one month of taking.

5. XXX, female, age 52, soft legs with slight edema, high blood pressure, frequent stuffy feeling, palpitation, dizziness, severe eczema, bad appetite, constipation, frequent insomnia. After the powder prepared in the embodiment 5 of the invention is taken three times a day, 25g is taken each time, after one month, the symptoms begin to improve, the palpitation and the dizziness are reduced, and the blood pressure tends to be normal. After 3 months, the eczema is completely eliminated, and the blood pressure is normal. Half a year later, the appetite is recovered and the sleep is good.

Through the verification of the examples, the morchella esculenta compound powder disclosed by the invention can be used for enhancing the human immune function and regulating the immune function. The functions are various: 1. reducing blood pressure, blood fat and blood sugar; 2. enhancing organism oxidation resistance, improving vascular endothelial function, and enhancing antioxidant activity; 3. antibacterial and anti-inflammatory effects; 4. reducing cholesterol content and blood viscosity, and preventing cardiovascular and cerebrovascular diseases such as hypertension, atherosclerosis and cerebral thrombosis; 5. Has antitumor activity; 6. increasing insulin content in vivo, accelerating hepatic glucose metabolism, and reducing postprandial blood sugar content.