阅读说明：本技术 水分散粒剂及其制备方法 (Water dispersible granule and preparation method thereof ) 是由 莫俊锐 韦沙迪 谭葵 廖联安 于 2021-07-27 设计创作，主要内容包括：本申请提供一种水分散粒剂及其制备方法。上述的水分散粒剂包括吡唑醚菌酯、啶酰菌胺、分散剂、润湿剂、助崩剂和填料。其中,所述分散剂包括木质素磺酸盐和线性表面活性剂。上述的水分散粒剂形成的分散体系稳定性较好且崩解率较高。(The application provides a water dispersible granule and a preparation method thereof. The water dispersible granule comprises pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler. Wherein the dispersant comprises lignosulfonate and a linear surfactant. The dispersion system formed by the water dispersible granule has better stability and higher disintegration rate.)

1. The water dispersible granule is characterized by comprising pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler;

wherein the dispersant comprises lignosulfonate and a linear surfactant.

2. The water dispersible granule according to claim 1, wherein the water dispersible granule comprises the following components in parts by mass:

3. the water dispersible granule according to claim 1, wherein the linear surfactant is at least one of a block copolymer dispersant, a polycarboxylate dispersant and a naphthalene sulphonate formaldehyde condensate dispersant.

4. The water dispersible granule according to claim 1, wherein the lignosulfonate is at least one of lignin Reax910, lignin D863, lignin G-NA and lignin Ufoxane 3A.

5. The water dispersible granule according to claim 1, wherein the wetting agent is at least one of a sulfate type wetting agent, an alkyl naphthalene sulfonate anion wetting agent and a dodecyl sulfonate.

6. The water dispersible granule according to claim 1, wherein the disintegration aid is at least one of anhydrous sodium sulphate, potassium sulphate, ammonium sulphate and urea.

7. Water dispersible granules according to any of claims 1 to 6, characterized in that the filler is a weakly acidic filler.

8. A preparation method of water dispersible granules is used for preparing the water dispersible granules as claimed in any one of claims 1 to 7, and comprises the following steps:

carrying out crushing operation on pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler to obtain a corresponding crushed material;

and granulating the crushed material to obtain the water dispersible granule.

9. The method for preparing water dispersible granules according to claim 8, wherein before the step of granulating the crushed material, and after the step of crushing pyraclostrobin, boscalid, a dispersant, a wetting agent, a disintegrating aid and a filler, the method for preparing water dispersible granules further comprises the following steps:

and mixing the crushed materials.

10. The method for preparing water dispersible granules according to claim 8 or 9, wherein the granulating operation of the crushed material comprises the following steps:

carrying out extrusion granulation treatment on the crushed materials;

and drying the crushed material subjected to the extrusion granulation treatment.

Technical Field

The invention relates to the technical field of pesticides, and particularly relates to a water dispersible granule and a preparation method thereof.

Background

The boscalid belongs to a novel nicotinamide fungicide, has no cross resistance with other fungicides, can block tricarboxylic acid cycle by mainly inhibiting mitochondrial succinate dehydrogenase, enables amino acid and sugar to be deficient, reduces energy, further interferes with cell division and growth, can be transferred in plants through foliar penetration, has protection and treatment effects on the plants, and the pyraclostrobin belongs to a methyl methoxyacrylate broad-spectrum fungicide with a pyrazole structure, is mainly transferred in the plants through the respiratory action of inhibiting pathogenic thalli and the foliar penetration, and further has the effect of preventing and treating plant diseases and insect pests. The boscalid and the pyraclostrobin are compounded for use, so that the boscalid and the pyraclostrobin have systemic property and protective and therapeutic effects, can penetrate into leaves and diffuse in mesophyll tissues after being applied for a few minutes, form a settled drug film on the leaves and be tightly adhered to a waxy layer, can effectively control pathogenic spores in the leaves, and have prevention effect and long drug effect duration.

Water dispersible granules have many advantages: (1) no organic solvent is used, no dust flies, the operation is safe, and the virulent varieties are low in toxicity; (2) the pesticide has high content of effective components and is unstable in water, and the prepared preparation formulation is better than an aqueous suspending agent, (3) compared with wettable powder and a suspending agent, the pesticide has high content of the effective components, higher hardness and relative density and good fluidity, can be packaged by paper bags, saves cost and is convenient to package, store and transport; (4) the disintegration speed is high, and the adaptability to water temperature and water quality is strong.

However, the melting point of the pyraclostrobin is 63.7-65.2 ℃, and the melting point is remarkably reduced after the pyraclostrobin is compounded with the boscalid, so that the melting point of the boscalid and the pyraclostrobin after compounding is further reduced, in addition, the boscalid and the pyraclostrobin are easy to melt in the processes of crushing, granulating and drying due to the fact that the processes of crushing, granulating and drying are required in the processing process of the water dispersible granule, extruded particles are bonded and not loose, and the pesticide effects of the boscalid and the pyraclostrobin are greatly reduced.

Disclosure of Invention

The invention aims to overcome the defects in the prior art and provides the water dispersible granule with good dispersion system stability and high disintegration rate and the preparation method thereof.

The purpose of the invention is realized by the following technical scheme:

a water dispersible granule comprises pyraclostrobin, boscalid, a dispersant, a wetting agent, a disintegrating aid and a filler;

wherein the dispersant comprises lignosulfonate and a linear surfactant.

In one embodiment, the water dispersible granule comprises the following components in parts by mass:

in one embodiment, the linear surfactant is at least one of a block copolymer dispersant, a polycarboxylate-type dispersant, and a naphthalene sulfonate formaldehyde condensate dispersant.

In one embodiment, the lignosulfonate is at least one of lignin Reax910, lignin D863, lignin G-NA, and lignin Ufoxane 3A.

In one embodiment, the wetting agent is at least one of a sulfate based wetting agent, an alkyl naphthalene sulfonate anion wetting agent, and dodecyl sulfonic acid.

In one embodiment, the disintegration aid is at least one of anhydrous sodium sulphate, potassium sulphate, ammonium sulphate and urea.

In one embodiment, the filler is a weakly acidic filler.

A preparation method of water dispersible granules is used for preparing the water dispersible granules in any embodiment, and comprises the following steps:

carrying out crushing operation on pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler to obtain a corresponding crushed material;

and granulating the crushed material to obtain the water dispersible granule.

In one embodiment, before the step of granulating the crushed material and after the step of crushing the pyraclostrobin, the boscalid, the dispersant, the wetting agent, the disintegrating aid and the filler, the preparation method of the water dispersible granule further comprises the following steps:

and mixing the crushed materials.

In one embodiment, the granulating operation of the pulverized material includes the following steps:

carrying out extrusion granulation treatment on the crushed materials;

and drying the crushed material subjected to the extrusion granulation treatment.

Compared with the prior art, the invention has at least the following advantages:

in the water dispersible granule, boscalid and pyraclostrobin are compounded for use, so that the water dispersible granule has good systemic property and a good effect of preventing and treating plant diseases and insect pests, and lignosulfonate and linear surfactant in a dispersant are used for acting on boscalid and pyraclostrobin which are compounded for use to form micelles containing boscalid and pyraclostrobin, wherein the lignosulfonate has a net structure, so that when the lignosulfonate acts on the boscalid and the pyraclostrobin, the lignosulfonate is paved on the surfaces of the boscalid and the pyraclostrobin which are compounded for use, and the linear surfactant has a linear structure, so that when the linear surfactant acts on the boscalid and the pyraclostrobin, the linear surfactant is filled in gaps of the net structure of the lignosulfonate, namely the lignosulfonate and the linear surfactant are wound to act on the boscalid and the pyraclostrobin which are compounded for use The micelle with a good coating effect is formed on the surfaces of the boscalid and the pyraclostrobin, so that the problem that after the boscalid and the pyraclostrobin in each micelle are melted, the boscalid and the pyraclostrobin in the adjacent micelle are contacted and bonded, and further the particle bonding and disintegration effects of the water dispersible granule are poor is solved, the lignosulfonate and the linear surfactant in the dispersing agent are matched with the wetting agent, the disintegration assistant and the filler for use, and the stability and the disintegration rate of a dispersing system of the water dispersible granule containing the boscalid and the pyraclostrobin are effectively improved.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.

Fig. 1 is a flow chart of a method for preparing water dispersible granules according to an embodiment of the present invention.

Detailed Description

To facilitate an understanding of the invention, the invention will now be described more fully with reference to the accompanying drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

The application provides a water dispersible granule. The water dispersible granule comprises pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler. Wherein the dispersant comprises lignosulfonate and linear surfactant.

In the water dispersible granule, boscalid and pyraclostrobin are compounded for use, so that the water dispersible granule has good systemic property and a good effect of preventing and treating plant diseases and insect pests, and a lignosulfonate and a linear surfactant in a dispersant are used for acting on the boscalid and the pyraclostrobin which are compounded for use to form a micelle containing the boscalid and the pyraclostrobin, wherein the lignosulfonate has a net structure, so that when a lignosulfonate acts on the boscalid and the pyraclostrobin, the lignosulfonate is paved on the surfaces of the boscalid and the pyraclostrobin which are compounded for use, and the linear surfactant has a linear structure, so that when the linear surfactant acts on the boscalid and the pyraclostrobin, the linear surfactant is filled in gaps of the net structure of the lignosulfonate, namely the lignosulfonate and the linear surfactant are wound to act on the boscalid and the pyraclostrobin which are compounded for use The micelle with a good coating effect is formed on the surfaces of the boscalid and the pyraclostrobin, so that the problem that after the boscalid and the pyraclostrobin in each micelle are melted, the boscalid and the pyraclostrobin in the adjacent micelle are contacted and bonded, and further the particle bonding and disintegration effects of the water dispersible granule are poor is solved, the lignosulfonate and the linear surfactant in the dispersing agent are matched with the wetting agent, the disintegration assistant and the filler for use, and the stability and the disintegration rate of a dispersing system of the water dispersible granule containing the boscalid and the pyraclostrobin are effectively improved.

The linear surfactant is a surfactant with a linear structure, one end of a molecule is a hydrophilic group, the other end of the molecule is a hydrophobic group, so that the linear surfactant can form a spherical micelle in water, namely, the hydrophilic part of the linear surfactant is distributed outside the micelle, the lipophilic part is distributed inside the micelle, the lignosulfonate has a net structure and is provided with a plurality of C3-C6 hydrophobic frameworks and a plurality of hydrophilic groups, so that the hydrophobic group of the lignosulfonate cannot form the micelle in water and only can play a role in compatibilization, namely, when the lignosulfonate is used as a dispersant, the lipophilic group is similar to and compatible with the lipophilic substance, and the hydrophilic group is represented as the lignosulfonate laid on the surface of the lipophilic substance along with the surrounding of the lipophilic group. When the linear surfactant and the lignosulfonate are used in a combined manner, the lignosulfonate is laid on the surfaces of boscalid and pyraclostrobin which are used in a compounding manner, the linear surfactant is filled in gaps of a network structure of the lignosulfonate to form micelles with compact coating structures, namely, the lignosulfonate and the linear surfactant are wound and act on the surfaces of the boscalid and the pyraclostrobin which are used in a compounding manner to form micelles with good coating effects on the surfaces of the boscalid and the pyraclostrobin, and therefore the problems that after the boscalid and the pyraclostrobin in each micelle are melted, the boscalid and the pyraclostrobin in adjacent micelles are contacted and bonded, and further the particle bonding and the disintegration effects of the water dispersible granule are poor are solved.

The lignosulfonate has good high-temperature resistance, and when the lignosulfonate and the linear surfactant are wound to act on the boscalid and the pyraclostrobin which are compounded for use to form micelles with good coating effects on the surfaces of the boscalid and the pyraclostrobin, the lignosulfonate is favorable for reducing the heat influence on the boscalid and the pyraclostrobin which are compounded for use, so that the micelles containing the boscalid and the pyraclostrobin are good in high-temperature stability, the melt temperature of the boscalid and the pyraclostrobin in compounding use is intuitively improved, the problem that the boscalid and the pyraclostrobin in each micelle are contacted and bonded with the boscalid and the pyraclostrobin in the adjacent micelles after being melted is further solved, the problem that the particles of the water dispersible granule are poor in bonding and disintegration effects is caused, and the water dispersible granule is dried at a high temperature without causing the bonding of the water dispersible granule is realized The stability and the disintegration rate of a dispersion system of the water dispersible granule containing boscalid and pyraclostrobin are improved.

In the water dispersible granule, boscalid and pyraclostrobin are compounded for use, so that the water dispersible granule has good systemic property and a good effect of preventing and treating plant diseases and insect pests, and lignosulfonate and linear surfactant in a dispersant are used for acting on boscalid and pyraclostrobin which are compounded for use to form micelles containing boscalid and pyraclostrobin, wherein the lignosulfonate has a net structure, so that when the lignosulfonate acts on the boscalid and the pyraclostrobin, the lignosulfonate is paved on the surfaces of the boscalid and the pyraclostrobin which are compounded for use, and the linear surfactant has a linear structure, so that when the linear surfactant acts on the boscalid and the pyraclostrobin, the linear surfactant is filled in gaps of the net structure of the lignosulfonate, namely the lignosulfonate and the linear surfactant are wound to act on the boscalid and the pyraclostrobin which are compounded for use The micelle with a good coating effect is formed on the surfaces of the boscalid and the pyraclostrobin, so that the problem that after the boscalid and the pyraclostrobin in each micelle are melted, the boscalid and the pyraclostrobin in the adjacent micelle are contacted and bonded, and further the particle bonding and disintegration effects of the water dispersible granule are poor is solved, the lignosulfonate and the linear surfactant in the dispersing agent are matched with the wetting agent, the disintegration assistant and the filler for use, and the stability and the disintegration rate of a dispersing system of the water dispersible granule containing the boscalid and the pyraclostrobin are effectively improved.

In one embodiment, the water dispersible granule comprises the following components in parts by mass: 10-15 parts of pyraclostrobin; 20-30 parts of boscalid; 10-21 parts of a dispersing agent; 2-5 parts of a wetting agent; 5-10 parts of a disintegration aid; 20 to 53 parts of filler. It can be understood that the melting point of the pyraclostrobin is lower, the pyraclostrobin and the boscalid are compounded for use, and the melting point of the compound of the pyraclostrobin and the boscalid is further lower, so that the total content of the pyraclostrobin and the boscalid in the water dispersible granule containing the pyraclostrobin and the boscalid is lower and generally not more than 30 percent, in order to improve the content of the pyraclostrobin and the boscalid in the water dispersible granule, 10-15 parts of the pyraclostrobin and 20-30 parts of the boscalid account for 30-45 percent of the total mass of the water dispersible granule, the content is higher, and the compound of 10-15 parts of the pyraclostrobin and 20-30 parts of the boscalid is matched with 10-21 parts of the lignosulfonate and the linear surfactant by mass, and is further matched with 2-5 parts of the wetting agent, 5-10 parts of the assistant agent and 20-53 parts of the filler for use, so that the compound of 10-15 parts of the pyraclostrobin and 20-30 parts of the boscalid still has a better dispersing effect, the water dispersible granule containing boscalid and pyraclostrobin has good dispersion system stability and high disintegration rate.

In one embodiment, the linear surfactant is at least one of a block copolymer dispersant, a polycarboxylate-type dispersant, and a naphthalene sulfonate formaldehyde condensate dispersant. It is understood that the block copolymer dispersant, the polycarboxylate dispersant and the naphthalenesulfonate formaldehyde condensate dispersant can be well filled in the gaps of the network structure of the lignosulfonate, namely, the lignosulfonate and the linear surfactant are wound on the surfaces of the boscalid and the pyraclostrobin which are compounded for use to form micelles with better coating tightness on the surfaces of the boscalid and the pyraclostrobin, thereby effectively reducing the mutual contact of the boscalid and the pyraclostrobin in each micelle, further, the problem that the bonding of particles of the water dispersible granule is poor due to the fact that the boscalid and the pyraclostrobin in each micelle are contacted and bonded with the boscalid and the pyraclostrobin in the adjacent micelle after the boscalid and the pyraclostrobin in each micelle are melted is solved, and the stability and the disintegration rate of a dispersion system of the water dispersible granule containing the boscalid and the pyraclostrobin are improved. It will also be appreciated that the hydrophobicity of the polycarboxylate dispersant molecule backbone and the hydrophilicity of the side chains and the side chain reactive group (methyl [ -CH)₃]Isobutyl [ -CCH₃]An ester group [ -COOR ]]Phenyl [ -C ]₆H₅]) In the presence of the compound, a certain three-dimensional stabilizing effect is exerted on the boscalid and the pyraclostrobin, so that the agglomeration resistance between the boscalid and the pyraclostrobin or the agglomeration resistance of the boscalid and the pyraclostrobin is increased; the dissociation of the block copolymer dispersant and the naphthalene sulfonate formaldehyde condensate dispersant is negative, which is helpful for leading the pyridine acylThe bactericidal composition containing the boscalid and the pyraclostrobin is mutually exclusive or mutually exclusive, so that the agglomeration resistance between the boscalid and the pyraclostrobin is increased, the bonding generated by the fact that the boscalid and the pyraclostrobin in each micelle are contacted with the boscalid and the pyraclostrobin in the adjacent micelle after the boscalid and the pyraclostrobin in each micelle are melted is relieved, and the stability and the disintegration rate of a dispersion system of the water dispersible granule containing the boscalid and the pyraclostrobin are improved.

In one embodiment, the polycarboxylate type dispersant is at least one of D518, D500, 2700, YUS-WG7, and D800. The main component of D518 was a sodium polycarboxylate. The main component of D500 is sodium polycarboxylate. 2700 contains sodium polycarboxylate as a main component. The main component of YUS-WG7 is sodium polycarboxylate. The main component of D800 is sodium polycarboxylate. It can be understood that D518, D500, 2700, YUS-WG7 and D800 can be well filled in gaps of a lignosulfonate mesh structure, and can be matched with lignosulfonate to act on the surfaces of boscalid and pyraclostrobin which are compounded for use to form micelles with good coating tightness on the surfaces of boscalid and pyraclostrobin, so that the stability and the disintegration rate of a dispersion system of the water dispersible granule containing boscalid and pyraclostrobin are improved.

In one embodiment, the naphthalene sulfonate formaldehyde condensate dispersant is at least one of a naphthalene sulfonate formaldehyde condensate and an alkyl naphthalene sulfonate formaldehyde condensate. The method has the advantages that both the naphthalenesulfonate formaldehyde condensate and the alkylnaphthalenesulfonate formaldehyde condensate can be well filled in gaps of a network structure of the lignosulfonate, and can be matched with the lignosulfonate to act on the surfaces of boscalid and pyraclostrobin which are compounded for use to form micelles with good coating tightness on the surfaces of the boscalid and the pyraclostrobin, so that the stability and the disintegration rate of a dispersion system of the water dispersible granule containing the boscalid and the pyraclostrobin are improved.

In one embodiment, the naphthalenesulfonate formaldehyde condensate dispersant is at least one of 207k, DT340, D-425, NNO, and AUX-L. The main component of 207k was a polynaphthalenecarboxylate anion. The main component of DT340 is a sodium naphthalenesulfonate formaldehyde condensate. The main component of D-425 is alkyl naphthalene sulfonic acid sodium salt formaldehyde condensate. The main component of NNO is naphthalene sulfonic acid sodium salt formaldehyde condensate. The main component of AUX-L is naphthalene sulfonic acid sodium salt formaldehyde condensate. It can be understood that 207k, DT340, D-425, NNO and AUX-L can be well filled in gaps of a lignosulfonate mesh structure, and can be matched with lignosulfonate to act on the surfaces of boscalid and pyraclostrobin which are used in a compounding mode to form micelles with good coating tightness on the surfaces of boscalid and pyraclostrobin, so that the stability and the disintegration rate of a water dispersible granule containing boscalid and pyraclostrobin are improved.

In one embodiment, the block copolymer dispersant is D-500. The main component of D-500 is AB type block polyether. The D-500 can be well filled in gaps of a lignosulfonate mesh structure, and can be matched with lignosulfonate to act on the surfaces of boscalid and pyraclostrobin which are compounded for use to form micelles with good coating tightness on the surfaces of boscalid and pyraclostrobin, so that the stability and the disintegration rate of a dispersing system of the water dispersible granule containing boscalid and pyraclostrobin are improved.

In one embodiment, the linear surfactant is a block copolymer dispersant and a naphthalene sulfonate formaldehyde condensate dispersant. It can be understood that the polarity of the pyraclostrobin is different from that of boscalid, a micelle formed by the block copolymer dispersant has quite strong solubilizing capability on the boscalid with smaller polarity, and a micelle formed by the naphthalenesulfonate formaldehyde condensate dispersant has quite strong solubilizing capability on the pyraclostrobin with larger polarity. Therefore, the block copolymer dispersant and the naphthalenesulfonate formaldehyde condensate dispersant are filled in the mesh gaps of the lignosulfonate together, so that more compact micelles are formed on the peripheries of the boscalid and the pyraclostrobin, the problem that the boscalid and the pyraclostrobin in each micelle are bonded after being melted and then contacted with the boscalid and the pyraclostrobin in the adjacent micelle, and further the particle bonding and disintegration effects of the water dispersible granule are poor is solved, the lignosulfonate, the block copolymer dispersant and the naphthalenesulfonate formaldehyde condensate dispersant in the dispersant are matched with the wetting agent, the disintegration assistant and the filler for use, and the stability and the disintegration rate of the water dispersible granule containing the boscalid and the pyraclostrobin are effectively improved.

In one embodiment, the mass ratio of the block copolymer dispersant to the naphthalenesulfonate formaldehyde condensate dispersant is 2/5-8/3, so that a more compact micelle is better formed at the periphery of boscalid and pyraclostrobin, the problem that after the boscalid and the pyraclostrobin in each micelle are melted, the boscalid and the pyraclostrobin are in contact with the boscalid and the pyraclostrobin in the adjacent micelle to be bonded, and further the particle bonding and disintegration effects of the water dispersible granule are poor is solved, the lignosulfonate, the block copolymer dispersant and the naphthalenesulfonate formaldehyde condensate dispersant in the dispersant are matched with the wetting agent, the disintegration assistant and the filler for use, and the stability and the disintegration rate of a water dispersible granule containing the boscalid and the pyraclostrobin are effectively improved.

In one embodiment, the lignosulfonate is at least one of lignin Reax910, lignin D863, lignin G-NA, and lignin Ufoxane 3A. The main component of lignin Reax910 is sodium lignosulfonate. The main component of lignin D863 is sodium lignosulfonate. The main component of the lignin G-NA is sodium lignosulfonate. The main component of the lignin Ufoxane3A is sodium lignosulfonate. It can be understood that the lignin Reax910, the lignin D863, the lignin G-NA and the lignin Ufoxane3A have better high-temperature resistance, are beneficial to reducing the influence of heat on boscalid and pyraclostrobin which are used in a compounding way, the micelle containing boscalid and pyraclostrobin inside has better high-temperature stability, intuitively shows that the melting temperature of the boscalid and the pyraclostrobin in the compounding use is improved, further reducing the bonding of the molten boscalid and the molten pyraclostrobin in each micelle and the adjacent boscalid and the molten pyraclostrobin in the micelle, further causing the problem of poor particle bonding and disintegration effects of the water dispersible granule, drying the granulated water dispersible granule at a higher temperature without causing the bonding of the water dispersible granule, and improving the stability and the disintegration rate of a dispersion system of the water dispersible granule containing boscalid and pyraclostrobin.

In one embodiment, the mass ratio of the lignosulfonate to the linear surfactant is 10/11-12/7, so that the linear surfactant is better ensured to be filled in gaps of a network structure of the lignosulfonate to form micelles with compact coating structures, and the stability and the disintegration rate of a dispersion system of the water dispersible granule containing boscalid and pyraclostrobin are improved.

In one embodiment, the water content of the water dispersible granule is 1-3%. It can be understood that the water dispersible granule is prepared by performing extrusion granulation or spray granulation on the ground material after being humidified by adding water, that is, the water dispersible granule has certain adhesive strength, and long columnar granules with good fluidity are formed by further utilizing the bonding stress during the extrusion granulation or spray granulation, however, if the water content of the dried water dispersible granule is low, the dried water dispersible granule is easy to be loosened to form powder, the yield of the water dispersible granule is influenced, and the utilization rate of the water dispersible granule is reduced; if the water content of the dried water dispersible granule is too high, the dried water dispersible granule is easy to bond, so that the disintegration speed and the dispersibility of the water dispersible granule are influenced, the water dispersible granule is easy to deteriorate in the storage process, and the drug effect of the water dispersible granule is reduced.

In one embodiment, the lignosulfonate has a reducing sugar content of 0.5% to 5.53%. It can be understood that the water dispersible granule is prepared by performing extrusion granulation or spray granulation on the ground material after being added with water and humidified, drying is needed after granulation, and in order to ensure the particle structure stability and the dispersion stability of the water dispersible granule, the water dispersible granule after drying needs to be kept with a certain water content, and in the water dispersible granule, the water content of the water dispersible granule is enabled to be 1-3%. However, if the water retention effect of the crushed material in the water dispersible granule is poor, the water content of the water dispersible granule is gradually reduced in the transportation and storage processes after the water content of the water dispersible granule is controlled to be 1% -3% during drying, so that the particles of the water dispersible granule are loosened, dust of the crushed material formed in a loose manner is blown, and the utilization rate of the water dispersible granule is reduced; if the water retention effect of the crushed materials in the water dispersible granules is better, the water in the particles of the water dispersible granules is difficult to remove, further leading the water quantity of the water dispersible granule to be difficult to reach 1-3 percent, further leading the dried water dispersible granule to be easy to be bonded, further influencing the disintegration speed and the dispersibility of the water dispersible granules, causing the water dispersible granules to easily deteriorate in the storage process, reducing the drug effect of the water dispersible granules, therefore, in the water dispersible granule of the application, in order to ensure the particle structure stability and the dispersion stability of the water dispersible granule, the content of reducing sugar in the lignosulfonate is 0.5-5.53 percent, the water-retaining stability of the water dispersible granule is effectively ensured, the drying degree of the water dispersing agent is effectively ensured, the looseness of water dispersible granule particles is reduced, and the disintegration speed, the dispersion stability and the drug effect of the water dispersible granule are improved. It can be understood that the lignin sulfonate molecules contain reducing sugar groups, and the content of the reducing sugar groups in the lignin sulfonate molecules has a great influence on the viscosity of the lignin sulfonate, when the content of the reducing sugar in the lignin sulfonate is lower than 0.5%, the water retention capacity of the crushed materials in the crushed materials is poor in the process of granulating the crushed materials, and the viscosity is low, so that the particles of the water dispersible granule are easy to loosen; if the content of the reducing sugar in the lignosulfonate is higher than 5.53%, the water retention capacity of the crushed materials in the crushed materials is stronger, the viscosity is higher, the water in the water dispersible granules is difficult to remove, the water amount of the water dispersible granules is difficult to reach 1% -3%, the dried water dispersible granules are easy to bond, the disintegration speed and the dispersibility of the water dispersible granules are influenced, the water dispersible granules are easy to deteriorate in the storage process, and the drug effect of the water dispersible granules is reduced. In one embodiment, the wetting agent is at least one of a sulfate based wetting agent, an alkyl naphthalene sulfonate anion wetting agent, and dodecyl sulfonic acid. It can be understood that the use of the sulfate wetting agent, the alkylnaphthalene sulfonate anion wetting agent and the dodecylsulfonic acid enables the water dispersible granule to have a better wetting effect, the wetting effect of the water dispersible granule is improved, and the disintegration speed and the dispersion stability of the water dispersible granule are further effectively improved.

In one embodiment, the sulfate-based wetting agent is at least one of YUS-SXC, L-WET/P, and Terwet 1004. It should be noted that the main component of YUS-SXC is C₁₀-C₁₄The main components of the alkyl derivative benzenesulfonic acid sodium salt and the L-WET/P are C₁₄～C₁₆Sodium alkenyl sulfonate. Terwet1004 is based on alkyl aryl sulfonate. As can be understood, the YUS-SXC, the L-WET/P and the Terwet1004 enable the water dispersible granule to have a good wetting effect, the wetting effect of the water dispersible granule is improved, and the disintegration speed and the dispersion stability of the water dispersible granule are further effectively improved.

In one embodiment, the sulfate-based wetting agent is YUS-TXC. The main component of YUS-TXC is phenolsulfonic acid formaldehyde phenol urea polymer sodium salt. As can be understood, the YUS-TXC enables the water dispersible granule to have a better wetting effect, improves the wetting effect of the water dispersible granule, and further effectively improves the disintegration speed and the dispersion stability of the water dispersible granule.

In one embodiment, the alkylnaphthalene sulfonate anionic wetting agent is MorwetEFW. It is noted that MorwetEFW comprises a mixture of alkyl naphthalene sulfonate and an anionic wetting agent as a major component. As can be understood, the MorwetEFW enables the water dispersible granule to have a good wetting effect, improves the wetting effect of the water dispersible granule, and further effectively improves the disintegration speed and the dispersion stability of the water dispersible granule.

In one embodiment, the disintegration aid is at least one of anhydrous sodium sulphate, potassium sulphate, ammonium sulphate and urea. The anhydrous sodium sulphate, the potassium sulfate, the ammonium sulfate and the urea are beneficial to eliminating the internal binding force of each water dispersible preparation particle of the water dispersible granule in the granulation process, the disintegration speed of the water dispersible granule is improved, the water dispersible granule is further promoted to form a stable dispersion system, and the speed of forming the stable dispersion system by the water dispersible granule is improved.

In one embodiment, the filler is a weakly acidic filler. The pyraclostrobin and the boscalid have high stability under an acidic condition, so that the filler is a weakly acidic filler, and the drug effect stability of the water dispersible granule is favorably improved.

In one embodiment, the PH of the filler is 5-7, so that the drug effect stability of the water dispersible granules is better realized.

The application also provides a preparation method of the water dispersible granule. The preparation method of the water dispersible granule is used for preparing the water dispersible granule in any embodiment. The preparation method of the water dispersible granule comprises the following steps: carrying out crushing operation on pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler to obtain a corresponding crushed material; and granulating the crushed material to obtain the water dispersible granule.

In the preparation method of the water dispersible granule, the pyraclostrobin, the boscalid, the dispersing agent, the wetting agent, the disintegration aid and the filler are crushed to obtain corresponding crushed materials, the dispersion uniformity of the dispersing agent, the pyraclostrobin and the boscalid is improved, the coating effect of the dispersing agent on the pyraclostrobin and the boscalid is favorably improved, and the uniformity of the water dispersible granule is improved.

In order to better understand the preparation method of the water dispersible granule of the present application, the following further explains the preparation method of the water dispersible granule of the present application, and the preparation method of the water dispersible granule of one embodiment includes the following steps:

s100, carrying out crushing operation on pyraclostrobin, boscalid, a dispersing agent, a wetting agent, a disintegrating aid and a filler to obtain a corresponding crushed material. The method has the advantages that the pyraclostrobin, the boscalid, the dispersing agent, the wetting agent, the disintegration assistant and the filler are crushed to obtain corresponding crushed materials, the dispersion uniformity of the dispersing agent, the pyraclostrobin and the boscalid is improved, the coating effect of the dispersing agent on the pyraclostrobin and the boscalid is favorably improved, the mixing uniformity of the pyraclostrobin, the boscalid, the dispersing agent, the wetting agent, the disintegration assistant and the filler is improved, and the uniformity of the water dispersible granule is improved.

S200, granulating the crushed materials to obtain the water dispersible granules, and ensuring the granularity and the flowability of the water dispersible granules by granulating the crushed materials.

In the preparation method of the water dispersible granule, the pyraclostrobin, the boscalid, the dispersing agent, the wetting agent, the disintegration aid and the filler are crushed to obtain corresponding crushed materials, the dispersion uniformity of the dispersing agent, the pyraclostrobin and the boscalid is improved, the coating effect of the dispersing agent on the pyraclostrobin and the boscalid is favorably improved, and the uniformity of the water dispersible granule is improved.

In one embodiment, the preparation method of the water dispersible granule comprises the following steps of: the crushed materials are mixed, so that the dispersion uniformity of each crushed material in the water dispersible granule is ensured.

In one embodiment, the mixing operation of the comminuted material comprises the steps of:

adding water and humidifying lignosulfonate, pyraclostrobin and boscalid in the crushed materials to obtain a primary mixture;

carrying out first mixing treatment on the primary mixture;

performing second mixing operation on the primary mixture subjected to the first mixing treatment and the linear surfactant in the crushed material to obtain an intermediate mixture;

a third mixing operation is performed on the intermediate mixture and the remaining material in the pulverized material.

It can be understood that the lignosulfonate, the pyraclostrobin and the boscalid in the crushed materials are subjected to water adding and humidifying treatment, the lignosulfonate can be favorably and fully covered on the surfaces of the pyraclostrobin and the boscalid, the primary mixture is further subjected to first mixing treatment, the lignosulfonate is fully covered on the surfaces of the pyraclostrobin and the boscalid, then the linear surfactant is added into the primary mixture for second mixing operation, the linear surfactant is fully filled in gaps of a network structure of the lignosulfonate, the linear surfactant and the lignosulfonate are wound and act on the surfaces of the boscalid and the pyraclostrobin which are used in a compounding mode to form micelles with good coating effects on the surfaces of the boscalid and the pyraclostrobin, and bonding caused by the fact that the boscalid and the pyraclostrobin inside each micelle are contacted with the adjacent boscalid and the pyraclostrobin inside each micelle after the boscalid and the pyraclostrobin are melted is relieved, and the third mixing operation is carried out on the intermediate mixture and the residual substances in the crushed materials, so that the formed micelle is well and uniformly mixed with the wetting agent, the disintegration assistant and the filler, the uniformity of the water dispersible granule is effectively improved, and the drug effect and the disintegration rate of the water dispersible granule are effectively improved.

The method is characterized in that if the linear surfactant and the lignosulfonate are added into the boscalid and the pyraclostrobin together, the linear surfactant is more directly formed into micelles containing the boscalid and the pyraclostrobin, so that the combination tightness and the high temperature resistance of the micelles at the peripheries of the boscalid and the pyraclostrobin are reduced, and the boscalid and the pyraclostrobin are easy to bond in the drying process to influence the disintegration rate and the pesticide effect. In addition, if the corresponding crushed materials are directly mixed, the lignosulfonate can play a role in wetting and compatibilization of the micelle, the filler and the disintegrant which contain the boscalid and the pyraclostrobin, so that the lignosulfonate is difficult to wind and act on the surfaces of the boscalid and the pyraclostrobin which are compounded and used with a linear surfactant to form micelles with good coating effects on the surfaces of the boscalid and the pyraclostrobin, and the adhesion caused by the fact that the boscalid and the pyraclostrobin inside each micelle are contacted with the boscalid and the pyraclostrobin inside the adjacent micelle after being melted is difficult to achieve.

In one embodiment, the granulation of the comminuted material comprises the steps of:

and extruding and granulating the crushed materials. The method has the advantages that in the extrusion granulation process, the friction force between the crushed materials is large, so that the temperature of the crushed materials is increased, the boscalid and the pyraclostrobin are easily melted, and the water dispersible granule is bonded.

Furthermore, the crushed material after extrusion granulation is dried, so that the water content of the water dispersible granule is ensured, the looseness of the water dispersible granule particles is reduced, and the disintegration speed, the dispersion stability and the drug effect of the water dispersible granule are improved.

Compared with the prior art, the invention has at least the following advantages:

in the water dispersible granule, boscalid and pyraclostrobin are compounded for use, so that the water dispersible granule has good systemic property and a good effect of preventing and treating plant diseases and insect pests, and lignosulfonate and linear surfactant in a dispersant are used for acting on boscalid and pyraclostrobin which are compounded for use to form micelles containing boscalid and pyraclostrobin, wherein due to the fact that lignosulfonate has a net structure, when lignosulfonate acts on boscalid and pyraclostrobin, lignosulfonate is laid on the surfaces of boscalid and pyraclostrobin which are compounded for use, and linear surfactant has a linear structure, when linear surfactant acts on boscalid and pyraclostrobin, linear surfactant is filled in gaps of the net structure of lignosulfonate, namely lignosulfonate and linear surfactant are wound to act on boscalid and pyraclostrobin which are compounded for use The micelle with a good coating effect is formed on the surfaces of the boscalid and the pyraclostrobin, so that the problem that after the boscalid and the pyraclostrobin in each micelle are melted, the boscalid and the pyraclostrobin in the adjacent micelle are contacted and bonded, and further the particle bonding and disintegration effects of the water dispersible granule are poor is solved, the lignosulfonate and the linear surfactant in the dispersing agent are matched with the wetting agent, the disintegration assistant and the filler for use, and the stability and the disintegration rate of a dispersing system of the water dispersible granule containing the boscalid and the pyraclostrobin are effectively improved.

Some specific examples are listed below, and if mentioned%, all are expressed in weight percent. It should be noted that the following examples are not intended to be exhaustive of all possible cases, and that the materials used in the following examples are commercially available without specific recitation.

Example 1

Respectively crushing 10kg of pyraclostrobin, 20kg of boscalid, 5kg of 2700 kg of boscalid, 5.5kg of Reax910, 2kg of YUS-SXC, 5kg of ammonium sulfate, 10kg of sodium citrate and 42.5kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed Reax910, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed 2700 into the mixture for fully mixing;

adding YUS-SXC, ammonium sulfate, sodium citrate and corn starch into the mixture, and fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 2

Respectively crushing 13kg of pyraclostrobin, 25kg of boscalid, 5kg of D500, 10kg of Ufoxane3A, 3kg of Terwet1004, 7kg of anhydrous sodium sulfate and 37kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed Ufoxane3A, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed D500 into the mixture for fully mixing;

adding Terwet1004, anhydrous sodium sulfate and corn starch into the mixture for fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 3

Respectively crushing 15kg of pyraclostrobin, 30kg of boscalid, 8kg of AUX-L, 12kg of lignin D863, 5kg of L-WET/P, 10kg of urea, 5kg of white carbon black and 15kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed lignin D863, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed AUX-L into the mixture for fully mixing;

adding L-WET/P, urea, white carbon black and corn starch into the mixture for fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 4

Respectively crushing 10kg of pyraclostrobin, 20kg of boscalid, 4kg of 2700, 4kg of 207k, 10kg of Reax910, 3kg of YUS-SXC, 10kg of ammonium sulfate, 10kg of sodium citrate and 29kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed Reax910, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed 2700 and 207k into the mixture for fully mixing;

adding YUS-SXC, ammonium sulfate, sodium citrate and corn starch into the mixture, and fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 5

Respectively crushing 13kg of pyraclostrobin, 25kg of boscalid, 8kg of D500, 3kg of DT340, 10kg of Ufoxane3A, 3kg of Terwet1004, 7kg of anhydrous sodium sulfate and 31kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed Ufoxane3A, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed D500 and DT340 into the mixture for fully mixing;

adding Terwet1004, anhydrous sodium sulfate and corn starch into the mixture for fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 6

Respectively crushing 13kg of pyraclostrobin, 25kg of boscalid, 2kg of D500, 5kg of D-425, 12kg of Ufoxane3A, 3kg of YUS-SXC, 10kg of potassium sulfate, 10kg of monopotassium phosphate and 20kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed Ufoxane3A, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed D500 and D-425 into the mixture for fully mixing;

adding YUS-SXC, potassium sulfate, potassium dihydrogen phosphate and corn starch into the mixture, and fully mixing to obtain a water-added humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 7

Respectively crushing 13kg of pyraclostrobin, 25kg of boscalid, 2kg of D518, 5kg of AUX-L, 10kg of Ufoxane3A, 3kg of L-WET/P, 10kg of anhydrous sodium sulfate, 5kg of white carbon black and 27kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed Ufoxane3A, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed D518 and AUX-L into the mixture for fully mixing;

adding L-WET/P, anhydrous sodium sulfate, white carbon black and corn starch into the mixture, and fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 8

Respectively crushing 15kg of pyraclostrobin, 30kg of boscalid, 5kg of D518, 5kg of D-425, 10kg of lignin D863, 3kg of YUS-SXC, 5kg of urea, 10kg of kaolin and 17kg of corn starch to obtain corresponding crushed materials for later use;

mixing the crushed lignin D863, pyraclostrobin and boscalid, and adding water for fully mixing to obtain a mixture;

adding the crushed D518 and D-425 into the mixture for fully mixing;

adding YUS-SXC, urea, kaolin and corn starch into the mixture, and fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

Example 9

Respectively crushing 13kg of pyraclostrobin, 20kg of boscalid, 5kg of NNO, 12kg of lignin LX, 3kg of YUS-SXC, 5kg of urea and 42kg of corn starch to obtain corresponding crushed materials for later use;

adding water into the crushed lignin LX, pyraclostrobin, boscalid, NNO, YUS-SXC, urea and corn starch, and fully mixing to obtain a water-added and humidified mixture;

and (3) extruding, granulating and drying the mixture added with water and humidified to obtain the water dispersible granule.

The water dispersible granules of examples 1-9 prepared by the preparation method of the water dispersible granule of the present application were subjected to the following performance tests:

the test results are shown in table 1:

table 1: various properties of water dispersible granules

The reducing sugar content of Reax910 was 1.33%. The reducing sugar content of D863 was 1.67%. The reducing sugar content of G-NA was 5.53%. The content of reducing sugar in Ufoxane3A is 0.5%, and the detection is based on GB/T8077-2000-.

It should be noted that the heat storage temperature is 54 ℃ and the heat storage time is 2 weeks.

From table 1, it can be seen that the water dispersible granules of examples 1 to 8 all have improved disintegration rate and heat storage disintegration rate, especially the water dispersible granules prepared by using the block copolymer dispersant, the naphthalenesulfonate formaldehyde condensate dispersant and the sodium lignosulfonate as the dispersants in examples 4 to 8 have better heat storage disintegration rate, and the water dispersible granules of examples 1 to 8 all have better yield and suspension rate.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.