阅读说明：本技术 一种畜禽用单宁酸包被预混制剂及其制备方法 (Tannin coated premixed preparation for livestock and poultry and preparation method thereof ) 是由 周建明 王乔飞 赵亚坤 孙兰 孙艳 于 2021-09-15 设计创作，主要内容包括：本发明提供一种畜禽用单宁酸包被预混制剂,按重量份计,复合预混制剂包括以下组分：单宁酸40～80份,高分子包衣材料5～20份,肠溶包衣材料20～50份。本发明的畜禽用单宁酸包被预混制剂,掩盖了单宁酸的苦涩味,不吸潮,不易氧化,产品稳定性好,便于贮存和使用,流动性好,便于下游饲料企业和用户分散预混,各项指标均符合相关要求。(The invention provides a tannin-coated premixed preparation for livestock and poultry, which comprises the following components in parts by weight: 40-80 parts of tannic acid, 5-20 parts of a polymer coating material and 20-50 parts of an enteric coating material. The tannic acid coating premixing preparation for livestock and poultry covers the bitter taste of tannic acid, does not absorb moisture, is not easy to oxidize, has good product stability, is convenient to store and use, has good fluidity, is convenient for downstream feed enterprises and users to disperse and premix, and all indexes meet related requirements.)

1. The tannin coating premixed preparation for livestock and poultry is characterized by comprising the following components in parts by weight: 40-80 parts of tannic acid, 5-20 parts of a polymer coating material and 20-50 parts of an enteric coating material.

2. The tannin-coated premixed preparation for livestock and poultry according to claim 1, wherein the polymer coating material is one or more of ethyl cellulose, cellulose acetate and hypromellose titanate.

3. The tannin-coated premixed preparation for livestock and poultry according to claim 1, wherein the enteric coating material is a combination of two or more of acrylic resin, shellac, and fat powder.

4. A preparation method of a tannin coating premix preparation for livestock and poultry is characterized by comprising the following steps:

s1, adding 5-20 parts of a polymer coating material into absolute ethyl alcohol, stirring and dissolving for 50-60 minutes to prepare first spraying liquid;

s2, adding 20-50 parts of enteric coating material into absolute ethyl alcohol, stirring and dissolving for 50-60 minutes to prepare second spraying liquid;

s3, adding 40-80 parts of tannic acid into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a first guniting solution to obtain tannic acid particles;

s4, adding the tannic acid particles into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a second guniting liquid;

s5, adjusting the temperature of the fluidized bed to be 30-40 ℃ for 40-50 minutes to enable ethanol to be fully volatilized, and then coating and discharging.

5. The method for preparing the tannin-coated premixed preparation for livestock and poultry according to claim 4, wherein the addition amount of the absolute ethyl alcohol of the step S1 is 20 to 30 percent of the total amount of the polymeric coating material.

6. The method for preparing the tannin-coated premixed preparation for livestock and poultry according to claim 4, wherein the addition amount of the absolute ethyl alcohol of the step S2 is 20 to 30 percent of the total amount of the enteric coating material.

Technical Field

The invention relates to the technical field of feed additives, in particular to a tannin-coated premixed preparation for livestock and poultry and a preparation method thereof.

Background

Tannin is a polyphenol natural plant extract widely existing in various plants, has no residue, is a feed additive approved by Ministry of agriculture in China, and has strong biological properties and pharmacological activity. The structure and activity are divided into two types: hydrolyzed tannic acid and condensed tannic acid, wherein the hydrolyzed tannic acid has been widely used as a feed additive, and its hydrolysis products gallic acid and glucose have an effect of improving growth performance and intestinal health of animals.

Most common preparations supplied in the current market are powder, are easy to absorb moisture and oxidize, and are bitter and astringent, so that the common preparations are often refused by the poultry and livestock to eat, which causes great inconvenience for use, poor product flowability and inconvenience for further uniform premixing.

Disclosure of Invention

The invention aims to overcome the defects in the prior art and provides a tannic acid coating premix preparation for livestock and poultry and a preparation method thereof, so that the tannic acid product has better stability and light astringency, is convenient for the livestock and poultry to absorb through gastrointestinal tracts, and simultaneously keeps good uniformity and fluidity of the product, and is convenient for downstream feed enterprises and users to premix.

The invention provides a tannin coating premixed preparation for livestock and poultry and a preparation method thereof, wherein the tannin is one of feed additives approved to be used by the Ministry of agriculture in China, and the polyphenol hydroxyl structure of the tannin determines that the tannin has good functions of astringency, diarrhea resistance, bacteriostasis, oxidation resistance, virus resistance, parasite resistance and the like; in the invention, proper high molecular material is firstly used for preparing primary coating slurry, tannin is primarily coated by adopting a unique bottom boiling guniting coating process to prepare particles, then enteric coating material is prepared into secondary coating slurry, and the formed primary coating particles are further coated by adopting a boiling guniting coating process, so that the bitter taste of the particles is covered, the prepared product has uniform content, good stability and uniform particles, good fluidity and is convenient for premixing and dispersing feed.

The technical scheme adopted by the invention is as follows:

a tannin coating premixed preparation for livestock and poultry, wherein the composite premixed preparation comprises the following components in parts by weight: 40-80 parts of tannic acid, 5-20 parts of a polymer coating material and 20-50 parts of an enteric coating material.

Preferably, the tannin coating premixed preparation for livestock and poultry, wherein the polymer coating material is one or more of ethyl cellulose, cellulose acetate and hydroxypropyl methylcellulose titanate.

Preferably, the tannin coating premixed preparation for livestock and poultry is prepared by coating two or more than two of acrylic resin, shellac and fat powder with the enteric coating material. The acrylic resin is one of acrylic resins I, II and III.

A preparation method of a tannin coating premix preparation for livestock and poultry comprises the following steps:

s1, adding 5-20 parts of a polymer coating material into absolute ethyl alcohol, stirring and dissolving for 50-60 minutes to prepare first spraying liquid;

s2, adding 20-50 parts of enteric coating material into absolute ethyl alcohol, stirring and dissolving for 50-60 minutes to prepare second spraying liquid;

s3, adding 40-80 parts of tannic acid into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a first guniting solution to obtain tannic acid particles;

s4, adding the tannic acid particles into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a second guniting liquid;

s5, adjusting the temperature of the fluidized bed to be 30-40 ℃ for 40-50 minutes to enable ethanol to be fully volatilized, and then coating and discharging.

Preferably, the preparation method of the tannin-coated premixed preparation for livestock and poultry, wherein the addition amount of the absolute ethyl alcohol in the step S1 is 20-30% of the total amount of the high molecular coating material.

Preferably, the preparation method of the tannin-coated premixed preparation for livestock and poultry, wherein the addition amount of the absolute ethyl alcohol in the step S2 is 20-30% of the total amount of the enteric coating material.

The invention has the advantages that: the tannic acid coating premixing preparation for livestock and poultry covers the bitter taste of tannic acid, does not absorb moisture, is not easy to oxidize, has good product stability, is convenient to store and use, has good fluidity, is convenient for downstream feed enterprises and users to disperse and premix, and all indexes meet related requirements.

Detailed Description

The present invention will be further described with reference to the following specific examples.

Example 1

A tannin coating premix preparation for livestock and poultry comprises the following components:

7000g of tannic acid, 100g of ethyl cellulose, 400g of hydroxypropyl methylcellulose titanate, 2500g of fat powder and 900g of absolute ethyl alcohol.

A method for preparing a tannin coated premixed preparation for livestock and poultry comprises the following steps:

s1, adding ethyl cellulose and hydroxypropyl methylcellulose titanate into 150g of absolute ethyl alcohol, stirring (stirring speed is 40 revolutions per minute) to dissolve for 50 minutes, and preparing first spraying slurry;

s2, adding the fat powder into 750g of absolute ethyl alcohol, stirring (stirring speed is 40 revolutions per minute) to dissolve for 50 minutes, and preparing second spraying liquid;

s3, adding the tannic acid into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a first guniting liquid to obtain tannic acid particles;

s4, adding the tannic acid particles into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a second guniting liquid;

s5, adjusting the temperature of the fluidized bed to be 30 ℃ for 50 minutes to enable ethanol to be fully volatilized, and then coating and discharging.

Example 2

A tannin coating premix preparation for livestock and poultry comprises the following components:

7000g of tannic acid, 300g of ethyl cellulose, 300g of cellulose acetate, 2700g of fat powder and 1000g of absolute ethyl alcohol.

A method for preparing a tannin coated premixed preparation for livestock and poultry comprises the following steps:

s1, adding ethyl cellulose and cellulose acetate into 180g of absolute ethyl alcohol, stirring (stirring speed is 40 r/min) to dissolve for 55 minutes, and preparing first slurry spraying liquid;

s2, adding the fat powder into 820g of absolute ethyl alcohol, stirring (stirring speed is 40 revolutions per minute) to dissolve for 55 minutes, and preparing second spraying liquid;

s3, adding the tannic acid into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a first guniting liquid to obtain tannic acid particles;

s4, adding the tannic acid particles into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a second guniting liquid;

s5, adjusting the temperature of the fluidized bed to 35 ℃ for 45 minutes to enable ethanol to be fully volatilized, and then coating and discharging.

Example 3

A tannin coating premix preparation for livestock and poultry comprises the following components:

7000g of tannic acid, 200g of cellulose acetate, 300g of hydroxypropyl methylcellulose titanate, 2200g of fat powder, 300g of polyacrylic resin II and 900g of absolute ethyl alcohol.

A method for preparing a tannin coated premixed preparation for livestock and poultry comprises the following steps:

s1, adding cellulose acetate and hydroxypropyl methylcellulose titanate into 150g of absolute ethyl alcohol, stirring (stirring speed is 40 revolutions per minute) to dissolve for 60 minutes, and preparing first slurry spraying liquid;

s2, adding the fat powder and the polyacrylic resin II into 750g of absolute ethyl alcohol, stirring (stirring speed is 40 revolutions per minute) to dissolve for 60 minutes, and preparing second spraying liquid;

s3, adding the tannic acid into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a first guniting liquid to obtain tannic acid particles;

s4, adding the tannic acid particles into a fluidized bed, and carrying out bottom boiling fluidized bed guniting through a second guniting liquid;

s5, adjusting the temperature of the fluidized bed to 40 ℃ for 40 minutes to enable the ethanol to be fully volatilized, and then coating and discharging.

Comparative example 1

Tannic acid which was not subjected to coating treatment was used as the uncoated group.

The properties of the non-coated tannic acid and the tannic acid (coated) premixed preparation for livestock and poultry prepared in the above examples 1 to 3 were checked by performing a stability acceleration test control.

The specific process is as follows: a sample of the premixed formulation coated with tannic acid for livestock and poultry prepared in examples 1 to 3, which was not coated with the feed additive, was subjected to a simulated commercial package, and was placed in a drug stability test chamber at a temperature of 40 ℃ ± 2 ℃ and a relative humidity of 75% ± 5% for 6 months, and the properties (appearance and fluidity, fluidity is expressed by angle of repose) were observed at the end of 1 month, 2 months, 3 months, and 6 months, respectively, with the results shown in table 1:

TABLE 1

As can be seen from Table 1: comparative example 1 the uncoated feed additive was poor in fluidity at 0 month, and the appearance and fluidity changed greatly at the end of one month in the accelerated test, while the tannic acid coated premixed preparation of the present invention still met the product quality requirements in appearance and fluidity after 6 months in the accelerated test, indicating good stability, and convenient for storage and use; good fluidity, and is convenient for downstream feed enterprises and users to disperse and premix.

The tannic acid coating premixing preparation for livestock and poultry covers the bitter taste of tannic acid, does not absorb moisture, is not easy to oxidize, has good product stability, is convenient to store and use, has good fluidity, is convenient for downstream feed enterprises and users to disperse and premix, and all indexes meet related requirements.

Finally, it should be noted that the above embodiments are only for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to examples, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, which should be covered by the claims of the present invention.