阅读说明：本技术 解郁香薰液及其制备方法和应用 (Depression-relieving aromatherapy liquid and preparation method and application thereof ) 是由 宋逍 张新博 汪芸兰 赵佩媛 孙静 于 2021-06-23 设计创作，主要内容包括：本发明属于香薰产品技术领域；涉及一种解郁香薰液及其制备方法和应用,解郁香薰液包括以下质量份数的原料：萱草50-70份、沉香20-40份以及柠檬10-30份；还包括质量份数1-5份的吐温-80。本发明原料天然,安全性好,香味清新自然,制备方法简单,保留香料的纯天然功效,稳定性良好；具有缓解情绪、醒脑提神、增进食欲的作用,可有效用于缓解抑郁症的药物中。(The invention belongs to the technical field of aromatherapy products; relates to depression relieving aromatherapy liquid and a preparation method and application thereof, wherein the depression relieving aromatherapy liquid comprises the following raw materials in parts by weight: 50-70 parts of hemerocallis fulva, 20-40 parts of agilawood and 10-30 parts of lemon; also comprises 1 to 5 parts of Tween-80 by mass. The perfume is natural in raw materials, good in safety, fresh and natural in fragrance, simple in preparation method, capable of keeping the pure natural effect of the perfume and good in stability; has the functions of relieving emotion, restoring consciousness, refreshing and promoting appetite, and can be effectively used in the medicine for relieving depression.)

1. The depression relieving aromatherapy liquid is characterized in that: the depression relieving aromatherapy liquid comprises the following raw materials in parts by weight: 50-70 parts of hemerocallis fulva, 20-40 parts of agilawood and 10-30 parts of lemon.

2. The depression-relieving aromatherapy liquid according to claim 1, wherein: the depression relieving aromatherapy liquid comprises the following raw materials in parts by weight: 65 parts of hemerocallis fulva, 35 parts of agilawood and 20 parts of lemon.

3. The depression-relieving aromatherapy liquid according to claim 2, wherein: the depression relieving aromatherapy liquid also comprises 1-5 parts of Tween-80 by mass.

4. The depression-relieving aromatherapy liquid according to claim 3, wherein: the mass portion of the Tween-80 is 3 portions.

5. The preparation method of the depression-relieving aromatherapy liquid according to claim 4, characterized by: the preparation method comprises the following steps:

1) weighing the raw materials according to the mass part of claim 4;

2) extracting the hemerocallis weighed in the step 1) with alcohol, recovering alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis extracting solution;

3) distilling the agilawood and the lemon weighed in the step 1) respectively to obtain agilawood volatile oil and lemon volatile oil correspondingly;

4) adding the hemerocallis fulva extracting solution obtained in the step 2) and the agilawood volatile oil and the lemon volatile oil obtained in the step 3) into tween-80 respectively and uniformly mixing to obtain the depression relieving aromatherapy liquid.

6. The method of claim 5, wherein: in the step 2), in the alcohol extraction process, the alcohol solution is ethanol, the volume fraction of the ethanol is 45-50%, the alcohol extraction temperature is 70-80 ℃, and the time is 2 hours.

7. The method of claim 6, wherein: in the step 3), the distillation time is 5-6 h.

8. Use of the depression-relieving aromatherapy liquid according to claim 4 for preparing a medicament for relieving depression.

Technical Field

The invention belongs to the technical field of aromatherapy products; relates to depression relieving aromatherapy liquid and a preparation method and application thereof.

Background

Depression is a common mental disease, mainly manifested by depressed mood, decreased interest, pessimism, slow thinking, lack of initiative, guilt oneself, poor diet and sleep, worrying about various diseases, feeling of discomfort in many places of the whole body, and suicidal thoughts and behaviors can appear in the serious people. Depression seriously disturbs the lives and work of patients, placing a heavy burden on families and society, and about 15% of depression patients die from suicide. A joint study by the world health organization, world bank and harvard university has shown that depression has become the second leading disease burden in china. Thus, focusing on depressed patients is also part of social responsibility.

Ancient incense is all natural perfume, but the traditional aromatherapy is generally ignited for use, smoke particles are generated during combustion to damage lungs, effective substances on which the aromatherapy depends can be damaged during the combustion process, and meanwhile, the danger of fire is caused; since the present generation, chemical essence has become the main raw material for incense production, such as incense sold in the market as sandalwood and agilawood, which only uses chemical essence with sandalwood fragrance or heavy fragrance. Compared with natural spices, the chemical essence has similar fragrance and even stronger fragrance, but the fragrance quality and the functions of soothing nerves, preserving health and enlightening sex do not speak in the same day. Many natural perfumes are listed as the top-grade medicinal materials, while synthetic perfumes as chemical products are fragrant and overflow at first smell, but are harmful to health when being used for multiple purposes; moreover, even with respect to odor alone, chemical flavors are only close to, and far from, natural flavors; so the natural aroma has good market prospect.

Disclosure of Invention

Aiming at the problems of the aromatherapy, the invention aims to disclose the depression relieving aromatherapy liquid and the preparation method thereof, wherein the depression relieving aromatherapy liquid is natural in raw materials, good in safety, fresh and natural in fragrance, simple in preparation method, capable of keeping the pure natural effect of the perfume and good in stability. Meanwhile, the depression relieving aromatherapy liquid has the effects of relieving emotion, restoring consciousness, refreshing and stimulating appetite, and can be effectively used in the medicine for relieving depression.

In order to realize the purpose, the invention adopts the technical scheme that:

the depression relieving aromatherapy liquid comprises the following raw materials in parts by weight: 50-70 parts of hemerocallis fulva, 20-40 parts of agilawood and 10-30 parts of lemon.

The depression relieving aromatherapy liquid comprises the following raw materials in parts by weight: 65 parts of hemerocallis fulva, 35 parts of agilawood and 20 parts of lemon.

The depression relieving aromatherapy liquid also comprises 1-5 parts of Tween-80 by mass.

The mass portion of the Tween-80 is 3 portions.

The preparation method of the depression relieving aromatherapy liquid comprises the following steps:

1) weighing the raw materials in parts by weight;

2) extracting the hemerocallis weighed in the step 1) with alcohol, recovering alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis extracting solution;

3) distilling the agilawood and the lemon weighed in the step 1) respectively to obtain agilawood volatile oil and lemon volatile oil correspondingly;

4) adding the hemerocallis fulva extracting solution obtained in the step 2) and the agilawood volatile oil and the lemon volatile oil obtained in the step 3) into tween-80 respectively and uniformly mixing to obtain the depression relieving aromatherapy liquid.

In the step 2), in the alcohol extraction process, the alcohol solution is ethanol, the volume fraction of the ethanol is 45-50%, the alcohol extraction temperature is 70-80 ℃, and the time is 2 hours.

In the step 3), the distillation time is 5-6 h.

Application of depression relieving aromatherapy liquid in preparing medicine for relieving depression is provided.

The invention has the beneficial effects that:

1. the depression relieving aromatherapy liquid provided by the invention comprises hemerocallis fulva, agilawood, lemon and tween-80. The hemerocallis are easy to worry about; the agilawood is fragrant and fresh, and refreshes the brain and refreshes the mind; the lemon has fresh fragrance, enhances an immune system, improves a circulatory system, revivifies and relieves dysphoria, the tween-80 (oleate) is an oil/water type emulsifier and can be used as a stabilizer, the three natural spices and the tween-80 are mutually synergistic according to a certain proportion to obtain the depression relieving aromatherapy liquid, the safety is good, the fragrance is lasting and fresh, the effects of relieving blood pressure and refreshing are achieved, and the lemon is well used for symptoms such as emotional tension and vasodilatation caused by depression.

2. According to the preparation method of the depression relieving aromatherapy liquid, the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil are respectively obtained through alcohol extraction and distillation and are mixed with the tween-80, so that the preparation method is simple in preparation process and easy to realize industrialization; meanwhile, the raw materials are purified, so that the purity is high, and the effect is better; and the aromatherapy liquid is volatilized in an ultrasonic atomization mode in an accelerated mode when in use, so that the smoke harm caused by the traditional incense can be avoided while effective substances are protected.

3. The prepared depression relieving aromatherapy liquid can improve blood circulation and reduce blood pressure, further relieve nervous and dysphoric emotions, refresh and restore consciousness, has fresh, natural and lasting fragrance, and can be effectively used in medicines for relieving depression.

Detailed Description

The present invention will now be described in detail with reference to examples.

The depression relieving aromatherapy liquid provided by the invention comprises hemerocallis fulva, agilawood, lemon and tween-80. The effects of the raw materials are as follows:

day lily: also known as day lily, forget-you-go-weed, etc., which are liliaceous plants, recorded in compendium of materia medica, and have the effects of widening chest diaphragm, calming five internal organs, relieving insomnia, relieving depression, clearing heat and nourishing heart. Clinical application shows that the Chinese medicinal composition has the effects of relieving depression, protecting liver, resisting oxidation and resisting tumor. Baihui was written that Dukang can relieve stuffiness and hemerocallis can relieve worry, meaning Dukang wine can relieve stuffiness in heart and hemerocallis can cause people to forget to worry and worry. Thus, day lily can be used for relieving depression for a long time.

Agilawood: the resiniferous Aquilaria sinensis of Thymelaeaceae contains solid condensate of oil (resin, density 0.912-0.938) and wood, and has fresh fragrance, refreshing and no dizziness after long-term use; refreshing the mind, and having pleasant feeling, but not causing people to be calm; the fragrance is mellow, the concentration is moderate, and the nasal cavity cannot be flushed when the nose is breathed deeply; even if the fragrance is strong, the user does not feel greasy, and even if the fragrance is mild, the fragrance is clear and recognizable; the trace of 'artificial fragrance' is not generated, and even if the fragrance is obvious, the natural quality can be realized; the human body is relaxed and the mind is calm and beautiful; has the feeling of nourishing the body and mind, so that people are willing to be close to each other; mellow smell, taste-resistant, multi-purpose and no weariness; the fragrance is lasting.

Lemon: fruit of Rutaceae plant Citrus aurantium or Citrus limonum, whose fresh aroma is derived from lemon essential oil (0.853), can improve circulatory system function, including promoting blood circulation, lowering blood pressure, and stopping nosebleed. It can enhance immune system, purify body, improve digestive system function, decompose cellulite, and treat dyspepsia and constipation; it has soothing and migraine relieving effects, helps to treat arthritis and rheumatism by synthesizing acidic substances in the body, and helps to clean acne, greasy skin and hair, and remove dead skin cells; can also refresh brain, refresh mind, relieve dysphoria, and can be used for treating depression; a few drops of lemon essential oil are dripped into hot water for soaking feet, so that the purpose of activating blood and meridians can be achieved, and the effect of removing beriberi and foot odor can be achieved.

Tween-8: generally referred to as polysorbate-80, also known as oleate. Is easily soluble in water, soluble in ethanol, vegetable oil, ethyl acetate, methanol, and toluene, and insoluble in mineral oil. It is gelatinized at low temperature and heated to recover. It is very smelly and slightly bitter. The dispersion of phthalocyanine green is facilitated. One of the surfactants commonly used in liquid formulations. Is an oil/water type emulsifier, and can be used as a stabilizer, a dispersing agent, an antistatic agent, a fiber lubricant, etc. Prepared by the reaction of sorbitan monooleate and ethylene oxide.

The depression relieving aromatherapy liquid provided by the invention comprises the following raw materials in parts by weight: 50-70 parts of hemerocallis fulva, 20-40 parts of agilawood and 10-30 parts of lemon.

Preferably, 65 parts of hemerocallis fulva, 35 parts of agilawood and 20 parts of lemon.

Further, the depression relieving aromatherapy liquid provided by the invention also comprises 1-5 parts of tween-80 by mass.

Preferably, the mass part of the tween-80 is 3 parts.

The preparation method of the depression relieving aromatherapy liquid provided by the invention comprises the following steps:

1) weighing the raw materials in parts by weight;

2) extracting hemerocallis fulva with alcohol, recovering alcohol, and volatilizing until no alcohol smell exists to obtain hemerocallis fulva extracting solution;

in the step 2), in the alcohol extraction process, the alcohol solution is ethanol, the volume fraction of the ethanol is 45-50%, the alcohol extraction temperature is 70-80 ℃, and the time is 2 hours;

3) distilling lignum Aquilariae Resinatum and fructus Citri Limoniae respectively to obtain lignum Aquilariae Resinatum volatile oil and fructus Citri Limoniae volatile oil; and during distillation, the distillation is carried out through steam, and the distillation time is 5-6 h.

4) Adding the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil into the tween-80 respectively, and uniformly mixing to obtain the depression relieving aromatherapy liquid.

According to the formula of the raw materials provided by the invention, the depression relieving aromatherapy liquid is prepared by alcohol extraction, distillation and mixing, the raw materials are natural, the safety is good, the fragrance is fresh and natural, the preparation process is simple, the final depression relieving aromatherapy liquid keeps the pure natural effect of the perfume, and the stability is good; meanwhile, the depression relieving aromatherapy liquid has the effects of relieving emotion and refreshing, and can be effectively used in the medicines for relieving depression.

The depression relieving aromatherapy liquid and the preparation method thereof provided by the invention are explained in detail by several groups of embodiments of the invention.

Example 1

The depression relieving aromatherapy liquid provided by the embodiment comprises the following raw materials in parts by weight: 50 parts of hemerocallis fulva, 40 parts of agilawood, 15 parts of lemon and 2 parts of tween-80.

The preparation method of the depression relieving aromatherapy liquid provided by the embodiment comprises the following steps:

1) weighing the raw materials according to the mass ratio for later use;

2) taking weighed hemerocallis fulva, placing the hemerocallis fulva in a round-bottom flask, extracting with 50% ethanol solution for 2 hours at 70 ℃, recovering the alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis fulva extracting solution;

3) respectively placing the weighed agilawood and the lemon into containers, distilling for 6 hours by using water vapor, and collecting volatile oil to obtain agilawood volatile oil and lemon volatile oil;

4) and finally, adding the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil into the weighed tween-80, and uniformly mixing to obtain the depression relieving aromatherapy liquid.

Example 2

The depression relieving aromatherapy liquid provided by the embodiment comprises the following raw materials in parts by weight: 65 parts of hemerocallis fulva, 35 parts of agilawood, 20 parts of lemon and 3 parts of tween-80.

The preparation method of the depression relieving aromatherapy liquid provided by the embodiment comprises the following steps:

1) weighing the raw materials according to the mass ratio for later use;

2) taking weighed hemerocallis fulva, placing the hemerocallis fulva in a round-bottom flask, extracting with 45% ethanol solution for 2 hours at 75 ℃, recovering the alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis fulva extracting solution;

3) placing the weighed agilawood and the lemon into containers respectively, distilling for 5 hours by using water vapor (the distillation temperature is 100 ℃), and collecting volatile oil to obtain agilawood volatile oil and lemon volatile oil;

4) and finally, adding the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil into the weighed tween-80, and uniformly mixing to obtain the depression relieving aromatherapy liquid.

Example 3

The depression relieving aromatherapy liquid provided by the embodiment comprises the following raw materials in parts by weight: 70 parts of hemerocallis fulva, 20 parts of agilawood, 30 parts of lemon and 3 parts of tween-80.

The preparation method of the depression relieving aromatherapy liquid provided by the embodiment comprises the following steps:

1) weighing the raw materials according to the mass ratio for later use;

2) taking weighed hemerocallis fulva, placing the hemerocallis fulva in a round-bottom flask, extracting with 50% ethanol solution for 2 hours at 80 ℃, recovering the alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis fulva extracting solution;

3) respectively placing the weighed agilawood and the lemon into containers, distilling for 5 hours by using water vapor, and collecting volatile oil to obtain agilawood volatile oil and lemon volatile oil;

4) and finally, adding the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil into the weighed tween-80, and uniformly mixing to obtain the depression relieving aromatherapy liquid.

Example 4

The depression relieving aromatherapy liquid provided by the embodiment comprises the following raw materials in parts by weight: 55 parts of hemerocallis fulva, 35 parts of agilawood, 10 parts of lemon and 1 part of tween-80.

The preparation method of the depression relieving aromatherapy liquid provided by the embodiment comprises the following steps:

1) weighing the raw materials according to the mass ratio for later use;

2) taking weighed hemerocallis fulva, placing the hemerocallis fulva in a round-bottom flask, extracting with 45% ethanol solution for 2 hours at 70 ℃, recovering the alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis fulva extracting solution;

3) respectively placing the weighed agilawood and the lemon into containers, distilling for 5 hours by using water vapor, and collecting volatile oil to obtain agilawood volatile oil and lemon volatile oil;

4) and finally, adding the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil into the weighed tween-80, and uniformly mixing to obtain the depression relieving aromatherapy liquid.

Example 5

The depression relieving aromatherapy liquid provided by the embodiment comprises the following raw materials in parts by weight: 60 parts of hemerocallis fulva, 30 parts of agilawood, 25 parts of lemon and 5 parts of tween-80.

The preparation method of the depression relieving aromatherapy liquid provided by the embodiment comprises the following steps:

1) weighing the raw materials according to the mass ratio for later use;

2) taking weighed hemerocallis fulva, placing the hemerocallis fulva in a round-bottom flask, extracting with 50% ethanol solution for 2 hours at 80 ℃, recovering the alcohol, and volatilizing until no alcohol smell exists to obtain a hemerocallis fulva extracting solution;

3) respectively placing the weighed agilawood and the lemon into containers, distilling for 6 hours by using water vapor, and collecting volatile oil to obtain agilawood volatile oil and lemon volatile oil;

4) and finally, adding the hemerocallis fulva extracting solution, the agilawood volatile oil and the lemon volatile oil into the weighed tween-80, and uniformly mixing to obtain the depression relieving aromatherapy liquid.

The depression relieving aromatherapy liquid prepared by the invention can be respectively filled in different containers, and is convenient to use.

Further, in order to illustrate the performance superiority of the depression-relieving aromatherapy liquid provided by the invention, the following tests are carried out.

Test 1 relative Density

The depression relieving aroma liquid prepared in the example 2 is selected, and the relative density is determined to be 0.98987g/ml by referring to the method specified in the GB/T11540-2008 spice relative density determination.

Test 2 fragrance Retention time

The depression relieving aromatherapy liquid prepared in the embodiment 2 is selected, sealed packages of samples are opened in a laboratory with 20-30 ℃ and no wind and no odor, contents are paved in a clean porcelain dish, and the samples are taken after being stored for 24 hours, so that the standard fragrance of the product is still obtained, which indicates that the fragrance is kept for a long time.

Test 3 heavy Metal Limit

The depression relieving aromatherapy liquid prepared in the embodiment 2 is selected, and the content of lead, arsenic, mercury and chromium in the depression relieving aromatherapy liquid is determined by a national standard heavy metal method. See table 1 for results.

TABLE 1 Depression relieving aromatherapy liquid heavy metal content detection result

As can be seen from Table 3, the depression relieving aromatherapy liquid provided by the invention has the advantages that the content of heavy metal ions is within the qualified range, no harm is caused to human bodies, and the safety is good.

Test 4 sensory evaluation

The depression relieving aromatherapy liquid provided by the embodiment 2 is selected and compared with a standard sample, and the depression relieving aromatherapy liquid is subjected to quality evaluation of appearance color, aroma and dissolving and mixing degree. In the test, the appearance color, aroma and definition were evaluated by methods commonly used in the industry, and the evaluation results are shown in table 2.

TABLE 2 sensory evaluation of depression-relieving aromatherapy solutions

As can be seen from the results in table 2, the color, aroma and clarity of the depression-relieving aromatherapy liquid provided by the embodiment all meet the requirements.

Test 5 stability

Selecting the depression relieving aromatherapy liquid provided in the embodiment 2, and observing the stability of the color after the lasting of the depression relieving aromatherapy liquid at the temperature of 48 +/-1 ℃ for 24 hours; the haze was observed at a temperature of 5 ℃ and the results are shown in Table 3.

TABLE 3 stability of depression relieving aromatherapy liquid

As can be seen from the results in table 3, the depression relieving aromatherapy liquid provided by the embodiment is still stable in color and luster in a heating state; the turbidity is clear and not turbid after the temperature is reduced, which indicates that no sediment or precipitate appears in the aromatherapy liquid when the temperature is reduced. The depression relieving aromatherapy liquid provided by the implementation has good stability.

Test 6 animal test

1. Animal grouping and modeling

(1) Grouping: the 60 mice (male half) were randomly divided into 15 mice each for the blank control group, the model control group, the conventional aromatherapy group, and the depression-relieving aromatherapy group.

(2) Molding: after all mice are normally bred for three days, the mice of the model control group, the conventional aromatherapy group and the depression relieving aromatherapy group are subjected to two stimulations of frightening the cat for 3 hours and depriving the sleep for 12 hours at random time every day for 15 days continuously. The sleep deprivation box uses a 60cm × 40cm × 30cm water tank, the water surface is deep enough to submerge the mouse, a 30mm diameter round table is placed in the center and 0.5cm above the water surface, and an iron net for mouse grains is placed above the water tank to ensure the food supply of the mouse. Cat scaring procedure in an open field 1.2 m in diameter, a cage containing a single mouse was placed in the center to attract cats to scare the mice, and fasting prior to the experiment was not given regular rewards to the live cats in order to ensure interest in the long-term experiment.

2. Intervention method

After molding, the conventional aromatherapy group is given with conventional aromatherapy (sandalwood), and the depression relieving aromatherapy group is given with the depression relieving aromatherapy liquid prepared in example 2 to perform an intervention experiment, wherein the intervention period is six days, and the food intake is measured periodically.

3. Food intake measurement: the food intake for 24 hours was calculated by adding 50g of food to mice at 0, 3, 6, 9, 12, 15, 18, and 21 morning days after normal feeding for three days, and weighing the food residue per mouse at 8:00 morning next day. Meanwhile, the weight of the mice was weighed, and the food consumption was determined as the amount of food consumed in 24 hours (mg)/body mass (g). Mice in the same cage were measured separately in isolated cages.

4. Results of the experiment

The food intake changes: according to the method, the food intake of each mouse of the blank control group, the model control group, the conventional aromatherapy group and the depression-relieving aromatherapy group on days 0, 3, 6, 9, 12, 15, 18 and 21 is measured respectively, and then the average value is obtained to obtain the average food intake of the mice of the model group and the mice of the control group. See table 4 for results.

TABLE 4 comparison of food intake for four groups of mice

	Blank control group	Model control group	Conventional aromatherapy kit	Depression relieving aromatherapy group
					0	220.33±65.16	218.75±92.85	219.64±54.24	219.96±85.14
3 days	223.21±89.54	219.69±72.43	218.99±89.69	218.45±17.86
					6 days	224.71±51.25	215.25±45.26	214.87±76.39	213.74±82.24
9 days	223.97±86.67	210.32±85.29	209.54±89.98	208.17±72.38
					12 days	225.14±45.62	203.39±99.12	205.47±65.54	202.64±54.29
15 days	225.36±87.86	194.85±87.25	197.14±78.28	197.22±58.62
					18 days	226.24±58.97	199.65±45.36	206.87±74.69	216.98±55.82
21 days	226.19±13.23	202.49±98.76	210.56±56.87	220.12±52.35

As can be seen from Table 4, compared with the blank control group, the food intake on day 0 of the model control group, the conventional aromatherapy group and the depression relieving aromatherapy group has no significant difference (P is more than 0.05). The food intake of mice of the model control group, the conventional aromatherapy group and the depression relieving aromatherapy group on days 3, 6, 9, 12 and 15 is reduced without significant difference (P is more than 0.05), compared with the blank control group, the mice of the model control group, the conventional aromatherapy group and the depression relieving aromatherapy group on day 18 have significant difference (P is less than 0.05), the food intake of the mice of the model control group, the conventional aromatherapy group and the depression relieving aromatherapy group on day 18 is in an ascending trend, the difference between the conventional aromatherapy group and the depression relieving aromatherapy group is significant (P is less than 0.05), and the model control group and the depression relieving aromatherapy group have significant difference (P is less than 0.05); on day 21, the food intake of the depression-relieving aromatherapy group mice was substantially restored to a normal state.

The performance of the depression relieving aromatherapy liquid provided by the embodiment 2 is only listed for verification, but the performance of the other embodiments is similar to that of the embodiment 2. The depression relieving aromatherapy liquid provided by the invention has the effects of relieving mood, refreshing and restoring consciousness, and stimulating appetite, can be used in anti-depression drugs, is beneficial to relieving depression symptoms, and has an effect superior to that of the conventional aromatherapy; meanwhile, the product is found to have the functions of relieving fatigue, repelling mosquitoes, relieving itching, improving air quality and the like in the using process, so that the application range of the product is expanded.