阅读说明：本技术 一种密封结构及使用其的制粒机双层密闭隔离装置 (Sealing structure and double-layer airtight isolating device of granulator using same ) 是由 张俊 杨国杰 于 2021-03-31 设计创作，主要内容包括：本发明涉及制粒机的技术领域,尤其涉及一种密封结构及使用其的制粒机双层密闭隔离装置,其中的密封结构包括：隔离面板,穿过隔离面板且与隔离面板转动连接的传动轴,位于隔离面板和传动轴之间的动密封组件,位于传动轴远离隔离面板一端的传动组件；以及传动轴的外侧壁与动密封组件和传动组件之间形成泄漏区域,且隔离面板与传动组件之间固定连接有一波纹管；其中波纹管能够密封泄漏区域,通过波纹管的设置堵住泄漏区域,对加工后的药粉起到二次密封的效果,避免毒药品泄露到外环境中危害人和环境,同时,波纹管为柔性材料,其自身具有伸缩功能,通过波纹管还能起到补偿动密封组件与隔离面板之间相对位移的作用。(The invention relates to the technical field of granulators, in particular to a sealing structure and a double-layer airtight isolating device of a granulator using the same, wherein the sealing structure comprises: the isolation panel, the transmission shaft which passes through the isolation panel and is rotationally connected with the isolation panel, the dynamic seal assembly which is positioned between the isolation panel and the transmission shaft, and the transmission assembly which is positioned at one end of the transmission shaft far away from the isolation panel; a leakage area is formed between the outer side wall of the transmission shaft and the dynamic sealing assembly and between the outer side wall of the transmission shaft and the transmission assembly, and a corrugated pipe is fixedly connected between the isolation panel and the transmission assembly; wherein the bellows can seal the leakage region, blocks up the leakage region through the setting of bellows, plays secondary seal's effect to the powder after the processing, avoids poison medicine to reveal harm people and environment in the external environment, and simultaneously, the bellows is flexible material, and it self has flexible function, can also play the effect of compensating relative displacement between dynamic seal subassembly and the isolation panel through the bellows.)

1. A sealing structure, comprising: the system comprises an outer isolation system, an inner isolation system arranged inside the outer isolation system, and a transmission sealing system;

the transmission sealing system comprises an isolation panel, a transmission shaft which penetrates through the isolation panel and is in rotary connection with the isolation panel, a dynamic sealing assembly positioned between the isolation panel and the transmission shaft, and a transmission assembly positioned at one end of the transmission shaft far away from the isolation panel,

the isolation panel is fixedly connected with the outer isolation system and the inner isolation system respectively, and the isolation panel forms sealing with the outer isolation system and the inner isolation system respectively; and

a leakage area is formed between the outer side wall of the transmission shaft and the dynamic sealing assembly and between the outer side wall of the transmission shaft and the transmission assembly, and a corrugated pipe is fixedly connected between the isolation panel and the transmission assembly; wherein

The bellows can seal the leakage area.

2. A sealing arrangement according to claim 1,

a gap exists between the isolation panel and the transmission shaft, the gap is communicated with the leakage area,

the dynamic seal assembly comprises an installation panel fixedly connected with the isolation panel, a support ring rotatably connected to the outer side wall of the transmission shaft, a dustproof retainer ring fixed on the support ring, and

one end of the corrugated pipe is fixedly connected with the mounting panel;

the dustproof check ring is positioned at one side close to the installation panel, and the dustproof check ring is propped against the back of the installation panel, wherein

The dustproof check ring can block materials from passing through the gap to enter the leakage area in advance.

3. A sealing arrangement according to claim 2,

the transmission assembly comprises an installation adjusting seat surrounding the outer side of the transmission shaft, a transmission bearing arranged between the installation adjusting seat and the transmission shaft, and a bearing cover covering the transmission bearing; and

the mounting adjusting seat is positioned at one end far away from the isolation panel;

the bearing cover is fixedly connected with the installation adjusting seat and is positioned at one side close to the isolation panel;

the other end of the corrugated pipe is fixedly connected with the bearing cover; wherein

The installation adjusting seat supports the transmission shaft to rotate through the transmission bearing.

4. A sealing arrangement according to claim 3,

the outer side wall of the transmission shaft is sleeved with a compression roller, the compression roller is positioned at one end in the inner separation system, and the compression roller is fixedly connected with the transmission shaft; and

the lateral wall cover in the middle part of transmission shaft is equipped with one and keeps off the ring, keep off the ring with the transmission shaft rotates to be connected, just keep off the ring and can follow the transmission shaft slides, wherein

The compression roller, the support ring, the baffle ring and the transmission bearing are sequentially abutted.

5. A sealing arrangement according to claim 4,

the side wall of the mounting panel is fixedly connected with a first fixing plate, and the first fixing plate is positioned at one side close to the bearing cover;

the side wall of the bearing cover is fixedly connected with a second fixing plate, and the second fixing plate is positioned at one side close to the mounting panel; and

and two ends of the corrugated pipe are respectively fixedly connected with the first fixing plate and the second fixing plate.

6. A sealing arrangement according to claim 5,

the inner isolation system also comprises an inner isolation cover main body fixedly connected with the isolation panel, an upper cover plate, a pressure plate and a lower cover plate which are sequentially and fixedly connected with the inner isolation cover main body from top to bottom, and

the bottom of the inner isolation cover main body is connected with a discharge pipe through a hose;

the transmission shaft extends into the inner isolation cover main body, and the compression roller is positioned in the inner isolation cover main body;

the upper cover plate, the pressing plate and the lower cover plate are respectively positioned on one side far away from the isolation panel;

the inner isolation cover main body is provided with a rear air seal at the joint of the inner isolation cover main body and the isolation panel;

the upper cover plate is provided with an upper air seal at the joint of the upper cover plate and the inner isolation cover main body;

the lower cover plate is provided with a lower air seal at the joint of the lower cover plate and the inner isolation cover main body; wherein

The upper cover plate, the pressing plate, the lower cover plate, the inner isolation cover main body and the isolation panel are mutually enclosed to form inner isolation.

7. A sealing arrangement according to claim 6,

the outer isolation system comprises an outer isolation cover main body covered outside the inner isolation cover main body, the outer isolation cover main body is fixedly connected with the isolation panel,

the discharge pipe penetrates through the bottom of the outer isolation cover main body and is fixedly connected with the outer isolation cover main body; and

two rows of operation openings which are arranged in a vertically stacked mode are formed in one side wall of the outer isolation cover main body, an operation door plate is hinged to an opening of each operation opening, and a plurality of glove rings are arranged on the operation door plates; wherein

The hand ferrule can extend into the inner cavity of the outer shield body.

8. A double-deck hermetic separator for a granulator, comprising a sealing structure according to claim 7.

9. A two-layer hermetic isolation device for a granulator according to claim 8,

the double-layer closed isolating device of the granulator further comprises a fresh air processing system and an exhaust air processing system which are arranged at the top of the outer isolating cover main body;

the fresh air processing system comprises a fresh air pneumatic valve, a fresh air filter and an air compression pneumatic valve, wherein the fresh air pneumatic valve penetrates through the top wall of the outer isolation hood main body, the fresh air filter is installed at the bottom of the fresh air pneumatic valve, and the air compression pneumatic valve is installed on one side of the top of the fresh air pneumatic valve;

the exhaust air processing system comprises a plurality of exhaust sleeves penetrating through the top wall of the main body of the outer isolation cover, and an exhaust filter and a total exhaust pipe are arranged in each exhaust sleeve; and

the exhaust sleeve is positioned above the inner isolation cover main body;

each exhaust sleeve is respectively communicated with the main exhaust pipe; wherein

The air passes the fresh air pneumatic valve and enters the inside of the outer isolation hood main body, and passes the main exhaust pipe to be discharged.

10. The double-layer airtight isolation apparatus for granulator of claim 9,

the top of the outer isolation cover main body is also provided with a feed valve, a conveyor communicated with the feed valve is arranged in the outer isolation cover main body, and the conveyor is communicated with the inner isolation cover main body; and

a continuous bag assembly at a sidewall of the outer cage body.

Technical Field

The invention relates to the technical field of granulators, in particular to a sealing structure and a double-layer airtight isolating device of a granulator using the same.

Background

A large proportion of the drugs today contain Active Pharmaceutical Ingredients (APIs) and highly active pharmaceutical ingredients (HPAPIs). During the preparation and formulation of the drug, the operator must be strictly protected. It is desirable to protect personnel and the environment by isolation containment techniques and clean-up systems to safely and efficiently perform api processing.

Therefore, a double-layer closed isolating device for the granulator for the extremely toxic medicines needs to be designed.

Disclosure of Invention

The invention aims to provide a double-layer closed isolating device of a granulator.

In order to solve the above technical problem, the present invention provides a sealing structure, including: the system comprises an outer isolation system, an inner isolation system arranged inside the outer isolation system, and a transmission sealing system; the transmission sealing system comprises an isolation panel, a transmission shaft, a dynamic sealing assembly and a transmission assembly, wherein the transmission shaft penetrates through the isolation panel and is rotatably connected with the isolation panel; a leakage area is formed between the outer side wall of the transmission shaft and the dynamic sealing assembly and between the outer side wall of the transmission shaft and the transmission assembly, and a corrugated pipe is fixedly connected between the isolation panel and the transmission assembly; wherein the bellows is capable of sealing the leakage area.

Furthermore, a gap exists between the isolation panel and the transmission shaft, the gap is communicated with the leakage area, the dynamic seal assembly comprises an installation panel fixedly connected with the isolation panel, a support ring rotatably connected to the outer side wall of the transmission shaft, a dustproof retainer ring fixed on the support ring, and one end of the corrugated pipe is fixedly connected with the installation panel; the dustproof check ring is located and is close to one side of installation panel, just the dustproof check ring with the back of installation panel offsets, wherein the dustproof check ring can block in advance that the material passes the clearance enters into let out in the leakage region.

Further, the transmission assembly comprises an installation adjusting seat surrounding the outer side of the transmission shaft, a transmission bearing arranged between the installation adjusting seat and the transmission shaft, and a bearing cover covering the transmission bearing; the installation adjusting seat is positioned at one end far away from the isolation panel; the bearing cover is fixedly connected with the installation adjusting seat and is positioned at one side close to the isolation panel; the other end of the corrugated pipe is fixedly connected with the bearing cover; wherein the installation adjusting seat supports the transmission shaft to rotate through the transmission bearing.

Furthermore, a compression roller is sleeved on the outer side wall of the transmission shaft and is positioned at one end in the inner isolation system, and the compression roller is fixedly connected with the transmission shaft; and the lateral wall cover at the middle part of transmission shaft is equipped with one and keeps off the ring, keep off the ring with the transmission shaft rotates to be connected, just keep off the ring and can follow the transmission shaft slides, wherein the compression roller the support ring keep off the ring with drive bearing offsets in proper order.

Further, a first fixing plate is fixedly connected to a side wall of the mounting panel, and the first fixing plate is located on one side close to the bearing cover; the side wall of the bearing cover is fixedly connected with a second fixing plate, and the second fixing plate is positioned at one side close to the mounting panel; and two ends of the corrugated pipe are respectively fixedly connected with the first fixing plate and the second fixing plate.

Furthermore, the inner isolation system also comprises an inner isolation cover main body fixedly connected with the isolation panel, an upper cover plate, a pressure plate and a lower cover plate which are sequentially and fixedly connected with the inner isolation cover main body from top to bottom, and the bottom of the inner isolation cover main body is connected with a discharge pipe through a hose; the transmission shaft extends into the inner isolation cover main body, and the compression roller is positioned in the inner isolation cover main body; the upper cover plate, the pressing plate and the lower cover plate are respectively positioned on one side far away from the isolation panel; the inner isolation cover main body is provided with a rear air seal at the joint of the inner isolation cover main body and the isolation panel; the upper cover plate is provided with an upper air seal at the joint of the upper cover plate and the inner isolation cover main body; the lower cover plate is provided with a lower air seal at the joint of the lower cover plate and the inner isolation cover main body; the upper cover plate, the pressing plate, the lower cover plate, the inner isolation cover main body and the isolation panel are mutually enclosed to form inner isolation.

Furthermore, the outer isolation system comprises an outer isolation cover main body covered outside the inner isolation cover main body, the outer isolation cover main body is fixedly connected with the isolation panel, and the discharge pipe penetrates through the bottom of the outer isolation cover main body and is fixedly connected with the outer isolation cover main body; two rows of operation openings which are arranged in a vertically stacked mode are formed in one side wall of the outer isolation cover main body, an operation door plate is hinged to an opening of each operation opening, and a plurality of glove rings are arranged on the operation door plates; wherein the hand ferrule is capable of extending into the inner cavity of the outer cage body.

In another aspect, the invention also provides a double-layer closed isolation device of a granulator, which comprises the sealing structure.

Furthermore, the double-layer closed isolating device of the granulator also comprises a fresh air processing system and an exhaust air processing system which are arranged at the top of the outer isolating cover main body; the fresh air processing system comprises a fresh air pneumatic valve, a fresh air filter and an air compression pneumatic valve, wherein the fresh air pneumatic valve penetrates through the top wall of the outer isolation hood main body, the fresh air filter is installed at the bottom of the fresh air pneumatic valve, and the air compression pneumatic valve is installed on one side of the top of the fresh air pneumatic valve; the exhaust air processing system comprises a plurality of exhaust sleeves penetrating through the top wall of the main body of the outer isolation cover, and an exhaust filter and a total exhaust pipe are arranged in each exhaust sleeve; the exhaust sleeve is positioned above the inner isolation cover main body; each exhaust sleeve is respectively communicated with the main exhaust pipe; wherein the air passes through the fresh air pneumatic valve and enters the interior of the outer isolation hood main body, and passes through the main exhaust pipe to be discharged.

Furthermore, a feeding valve is further installed at the top of the outer isolation cover main body, a conveyor communicated with the feeding valve is installed inside the outer isolation cover main body, and the conveyor is communicated with the inner isolation cover main body; and a continuous bag assembly at a sidewall of the outer cage body.

The sealing structure and the granulator double-layer closed isolating device using the sealing structure have the advantages that the corrugated pipe is fixedly connected between the isolating panel and the transmission assembly, namely the corrugated pipe is positioned at the opening of the leakage area, the leakage area is blocked through the arrangement of the corrugated pipe, the secondary sealing effect is achieved on processed medicinal powder, toxic medicines are prevented from leaking into an external environment to harm people and the environment, meanwhile, the corrugated pipe is made of flexible materials and has a telescopic function, and the effect of compensating relative displacement between the movable sealing assembly and the isolating panel can be achieved through the corrugated pipe.

Drawings

The invention is further illustrated with reference to the following figures and examples.

FIG. 1 is a perspective view of a preferred embodiment of a double-deck hermetic separator of a granulator of the present invention;

FIG. 2 is a top view of a preferred embodiment of a two-layer hermetic separator of a granulator of the present invention;

FIG. 3 is a cross-sectional view of section B-B of FIG. 2;

FIG. 4 is a cross-sectional view of section A-A of FIG. 3;

FIG. 5 is a schematic structural view of a preferred embodiment of the transmission sealing system of the present invention;

FIG. 6 is a schematic structural view of a preferred embodiment of the support ring of the present invention;

FIG. 7 is a schematic structural view of a preferred embodiment of the dust retainer of the present invention;

FIG. 8 is a front view of a preferred embodiment of a double-deck hermetic separator of a granulator of the present invention.

In the figure:

an external isolation system 1, an external isolation cover main body 11, an operation door panel 12, a glove ring 121 and a door handle 122;

the inner isolation system 2, the inner isolation cover main body 21, the pressing handle 211, the upper cover plate 22, the pressing plate 23, the lower cover plate 24, the viewing mirror opening 241, the sampling opening 242, the hose 25, the discharge pipe 26, the rear air seal 27, the upper air seal 28 and the lower air seal 29;

the device comprises a transmission sealing system 3, an isolation panel 31, a transmission shaft 32, a dynamic sealing component 33, a mounting panel 331, a support ring 332, a first support plate 3321, a second support plate 3322, a third support plate 3323, a mounting groove 3324, a plugging position 3325, a dustproof retainer ring 333, a collision ring 334, a transmission component 34, a mounting adjusting seat 341, a transmission bearing 342, a bearing cover 343, a leakage area 35, a corrugated pipe 36, a compression roller 37, a plugging plate 371, a retainer ring 38, a first fixing plate 391 and a second fixing plate 392;

a fresh air processing system 4, a fresh air pneumatic valve 41, a fresh air filter 42 and an air compression pneumatic valve 43;

an exhaust air processing system 5, an exhaust sleeve 51, an exhaust filter 52, and a main exhaust duct 53;

a temperature and humidity detection component 6;

a differential pressure detection assembly 7;

a feed valve 8, a conveyor 81;

a continuous bag assembly 9;

technical area 10.

Detailed Description

The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic views illustrating only the basic structure of the present invention in a schematic manner, and thus show only the constitution related to the present invention.

Example one

As shown in fig. 1 to 8, the sealing structure of the present invention satisfies the sealing and safety of granulation production and sampling of toxic drugs in a dry granulator, and comprises an outer isolation system 1, an inner isolation system 2 and a transmission sealing system 3, wherein the inner isolation system 2 is located inside the outer isolation system 1, so as to be integrally formed, and the outer isolation system 1 prevents the toxic drugs from leaking into the external environment to harm people and the environment, and provides a clean environment with constant temperature and humidity for drug production; the working area of the dry granulation is sealed and isolated by the inner isolation system 2, the medicine powder visible to naked eyes is prevented from entering and exiting the outer isolation system 1, the medicine powder is prevented from leaking into the outer isolation system 1 when the equipment is produced, the medicine powder is prevented from leaking into the technical area 10 of the dry granulator when the dry granulator is produced by the transmission sealing system 3, and the maintenance and cleaning times of the equipment are reduced; and the controllability of the production area is greatly increased, thereby reducing the operation cost and the maintenance cost, wherein the transmission sealing system 3 is provided with an isolation panel 31; the isolation panel 31 is fixedly connected with the outer isolation system 1 and the inner isolation system 2 respectively, and the isolation panel 31 forms a seal with the outer isolation system 1 and the inner isolation system 2 respectively; a transmission shaft 32 is arranged through the isolation panel 31, the transmission shaft 32 is rotatably connected with the isolation panel 31, a movable sealing assembly 33 is generally arranged between the isolation panel 31 and the transmission shaft 32, the movable sealing assembly 33 plays a role of primary sealing for the processed medicine powder, but when different medicine thicknesses are processed, the movable sealing assembly 33 can move up and down relative to the isolation panel 31, so that the medicine can be extruded to form the medicine powder and then can be leaked out from the movable sealing assembly 33, meanwhile, only a transmission assembly 34 for supporting the transmission shaft 32 to rotate is arranged at the other end of the transmission shaft 32, namely, the transmission assembly 34 is arranged at one end far away from the isolation panel 31, a leakage area 35 is formed between the outer side wall of the transmission shaft 32 and the movable sealing assembly 33 and the transmission assembly 34, and the medicine powder leaked out from the movable sealing assembly 33 can also leak out from the leakage area 35, in order to solve the above problems, it is necessary to design a solution,

a corrugated pipe 36 is fixedly connected between the isolation panel 31 and the transmission assembly 34, that is, the corrugated pipe 36 is located at an opening of the leakage area 35, the leakage area 35 is blocked by the arrangement of the corrugated pipe 36, a secondary sealing effect is achieved on the processed medicinal powder, and toxic medicine is prevented from being leaked to an external environment to harm people and the environment, meanwhile, the corrugated pipe 36 is made of a flexible material and has a telescopic function, when the movable sealing assembly 33 and the isolation panel 31 are in relative displacement, the corrugated pipe 36 can keep the movable sealing assembly 33 and the isolation panel 31 connected, and the corrugated pipe 36 can also play a role in compensating the relative displacement between the movable sealing assembly 33 and the isolation panel 31.

In this embodiment, the drive shaft 32 is rotated by coupling the drive shaft 32 to a motor, which is also located at one end of the drive assembly 34.

A gap is formed between the isolation panel 31 and the transmission shaft 32, the gap is communicated with the leakage area 35, the movable sealing assembly 33 is used for sealing the gap, and the structure of the movable sealing assembly 33 is as follows, the movable sealing assembly 33 comprises a mounting panel 331 fixedly connected with the isolation panel 31, the mounting panel 331 is in a ring shape, the mounting panel 331 is fixed with the isolation panel 31 through bolts, the mounting panel 331 is used for fixing the corrugated pipe 36, the mounting panel 331 is positioned at one side of the isolation panel 31 close to the transmission assembly 34, the bottom end of the mounting panel 331 protrudes out of the bottom end of the isolation panel 31, namely the mounting panel 331 extends into the leakage area 35, the mounting panel 331 can guide the medicine powder leaked in the gap, can guide the medicine powder into the leakage area 35 and avoid the medicine powder from escaping, and meanwhile, a sealing ring is further arranged at the joint of the mounting panel 331 and the isolation panel 31, a support ring 332 is rotatably connected to an outer side wall of the transmission shaft 32 to prevent the powder from leaking upward, a dust-proof ring 333 is fixed to the support ring 332, and specifically, a cross section of the support ring 332 is composed of a first support plate 3321 parallel to the isolation panel 31, and a second support plate 3322 and a third support plate 3323 perpendicular to an inner side and an outer side of the first support plate 3321, the second support plate 3322 is located on a top portion of the first support plate 3321, the second support plate 3322 extends toward the installation panel 331, but a slit is formed between the second support plate 3322 and the installation panel 331, a rectangular installation groove 3324 is formed at a position of the second support plate 3322 near the slit, the installation groove 3324 is annular as a whole, the dust-proof ring 333 is installed in the installation groove 3324, and a contact ring 334 is obliquely extended from the dust-proof ring 333 toward the installation panel 331, the contact ring 334 blocks the slit and contacts the installation panel 331, when the transmission shaft 32 rotates to drive the whole support ring 332 to rotate, the interference ring 334 can be kept to abut against the back of the mounting panel 331, so that dynamic sealing is realized, and meanwhile, the medicinal powder is leaked from the interference ring 334 and the back of the mounting panel 331 to the leakage area 35; the processed medicine powder can be blocked in advance by the dustproof check ring 333, and the medicine powder passing through the dustproof check ring 333 enters the leakage area 35 and can be blocked by the corrugated pipe 36, so that the medicine powder is prevented from leaking into the air to the greatest extent and damaging human bodies.

The specific structure of the transmission assembly 34 is as follows, the transmission assembly 34 includes an installation adjustment seat 341 surrounding the outside of the transmission shaft 32, the installation adjustment seat 341 is located at one end of the transmission shaft 32 far from the isolation panel 31, the installation adjustment seat 341 only covers the transmission shaft 32, but the installation adjustment seat 341 does not contact with the transmission shaft 32, specifically, the installation adjustment seat 341 is installed in the technical area 10 at the rear side, a transmission bearing 342 is installed between the installation adjustment seat 341 and the transmission shaft 32, the outer side wall of the transmission bearing 342 is attached to the inner side wall of the installation adjustment seat 341, the inner side wall of the transmission bearing 342 is attached to the transmission shaft 32 to support the transmission shaft 32 to rotate, after the transmission bearing 342 is installed in the installation adjustment seat 341, a bearing cover 343 is installed at the side taken out to avoid the situation that the transmission bearing comes out, the bearing cover 343 is fixedly connected to the installation adjustment seat 341, specifically, the bearing cover 343 and the installation adjusting seat 341 are fixed by bolts, and the bearing cover 343 is located at a side close to the isolation panel 31; the other end of the bellows 36 is fixedly connected to the bearing cover 343.

In order to further avoid leakage of the medicinal powder, specifically to avoid leakage of the medicinal powder along the axial sliding of the transmission shaft 32, a pressing roller 37 is sleeved on the outer side wall of the transmission shaft 32, the pressing roller 37 is located at one end inside the inner isolation system 2, that is, the pressing roller 37 is located at one end far away from the installation adjusting seat 341, and the pressing roller 37 is fixedly connected with the transmission shaft 32, that is, the pressing roller 37 can rotate along with the transmission shaft 32, so as to realize extrusion of the medicine fed into the inner isolation system 2, and meanwhile, the pressing roller 37 can achieve the effect of isolating the medicinal powder from the transmission shaft 32 at the section of the pressing roller 37; and the outer side wall of the middle part of the transmission shaft 32 is sleeved with a baffle ring 38, the baffle ring 38 is rotatably connected with the transmission shaft 32, and the baffle ring 38 can slide along the transmission shaft 32, when in installation, the press roller 37, the support ring 332 and the baffle ring 38 are sequentially abutted against the transmission bearing 342, so that the press roller 37, the support ring 332, the baffle ring 38 and the transmission bearing 342 form a protective sleeve to protect the transmission shaft 32, and the contact between the medicinal powder in the internal isolation system 2 or the medicinal powder in the leakage area and the transmission shaft 32 is avoided, when the specific press roller 37 is abutted against the support ring 332, the area between the third support plate 3323 and the transmission shaft 32 as well as the first support plate 3321 is the insertion position 3325, the press roller 37 extends to the support ring 332 to form an insertion plate 371, the insertion plate 371 is just inserted into the insertion position 3325, at this time, the third support plate 3323 not only plays a role in limiting the insertion plate 371, also play the effect that blocks medicine powder and transmission shaft 32 contact simultaneously, form "ㄣ" shape between plugboard 371 and third backup pad 3323 and the first backup pad 3321, such mode is if medicine powder need turn two right angle bends with transmission shaft 32 contact, such effect of blockking to medicine powder is better, and again and insert the mode of grafting position 3325 through plugboard 371 and can guarantee to touch ring 334 and installation panel 331 and laminate mutually, further improve the sealed effect of touch ring 334, first backup pad 3321 also is laminated with transmission shaft 32, also play isolated transmission shaft 32 and be stained with the effect of medicine powder.

In order to realize the disassembly and assembly of the bellows 36, a first fixing plate 391 is fixedly connected to a side wall of the mounting panel 331, and the first fixing plate 391 is located at a side close to the bearing cover 343, specifically, the first fixing plate 391 can be fixed on the mounting panel 331 by bolts, and a bottom end of the first fixing plate 391 is flush with the mounting panel 331; a second fixing plate 392 is fixedly connected to a side wall of the bearing cover 343, and the second fixing plate 392 is located at a side close to the mounting panel 331, specifically, the second fixing plate 392 may also be fixed to the bearing cover 343 by bolts; two ends of the corrugated tube 36 are respectively fixedly connected with the first fixing plate 391 and the second fixing plate 392, so that when the corrugated tube 36 needs to be disassembled and assembled, only corresponding bolts need to be unscrewed or screwed, and convenience is provided for disassembling and assembling the corrugated tube 36. In this embodiment, sealing rings are respectively installed between the first fixing plate 391 and the mounting panel 331 and between the second fixing plate 392 and the bearing cover 343 to ensure airtightness.

The specific inner isolation system 2 is as follows, the inner isolation system 2 further comprises an inner isolation hood main body 21 fixedly connected with the isolation panel 31, an upper cover plate 22, a pressing plate 23 and a lower cover plate 24 fixedly connected with the inner isolation hood main body 21 in sequence from top to bottom, an inner isolation chamber is formed by the inner isolation hood main body 21, the upper cover plate 22, the pressing plate 23, the lower cover plate 24 and the isolation panel 31 to avoid the medicinal powder from escaping, the medicine is conveyed into the chamber and extruded into medicinal powder by a pressing roller 37, a discharge pipe 26 is connected to the bottom of the inner isolation hood main body 21 through a hose 25, the hose 25 is convenient to discharge, specifically, when the medicinal powder is adhered to the inner wall of the hose 25 and even blocks the discharge pipe 26, the hose 25 can be shaken by manual work to shake the medicinal powder so as to dredge the discharge pipe 26, and the human body does not need to contact the medicinal powder when the hose is dredged, the safety of people is further ensured; the transmission shaft 32 extends into the inner isolation cover main body 21, the press roller 37 is located in the inner isolation cover main body 21, the upper cover plate 22, the press plate 23 and the lower cover plate 24 are respectively located at one side far away from the isolation panel 31, that is, the inner isolation cover main body 21 is a frame body, one side of which is blocked by the isolation panel 31, and the other side of which is blocked by the upper cover plate 22, the press plate 23 and the lower cover plate 24; the inner isolation hood main body 21 is provided with a rear air seal 27 at the joint with the isolation panel 31; the upper cover plate 22 is provided with an upper air seal 28 at the joint with the inner isolation cover main body 21; the lower cover plate 24 is provided with a lower air seal 29 at the joint with the inner isolation cover main body 21, and the whole air tightness of the inner isolation chamber is realized through a rear air seal 27, an upper air seal 28 and the lower air seal 29.

In this embodiment, a plurality of pressing handles 211 are installed on the inner isolation cover main body 21 to open and close the upper cover plate 22 and the lower cover plate 24; a viewing mirror opening 241 is arranged on the lower cover plate 24, and the processing condition of the medicine can be conveniently observed through the arrangement of the viewing mirror opening 241; the lower cover plate 24 is further provided with a sampling port 242, and the processed powder can be sampled through the sampling port 242.

The specific outer isolation system 1 is as follows, the outer isolation system 1 comprises an outer isolation cover main body 11 covering the outer part of the inner isolation cover main body 21, the outer isolation cover main body 11 is fixedly connected with the isolation panel 31, an outer isolation chamber is formed by enclosing the outer isolation cover main body 11 and the isolation panel 31, and the discharge pipe 26 penetrates through the bottom of the outer isolation cover main body 11 and is fixedly connected with the outer isolation cover main body 11; two operation openings which are arranged in a vertically stacked manner are formed in one side wall of the outer isolation cover main body 11, an operation door panel 12 is hinged to an opening of each operation opening, and a plurality of glove rings 121 are arranged on the operation door panels 12; when the glove is used, an operator can stretch hands into the corresponding glove rings 121 to operate the external isolation chamber, so that the hands are prevented from being stained with medicinal powder while the operation is realized, the operation is facilitated, and the safety of the operator is guaranteed; in this embodiment, the operating door panel 12 is made of transparent glass and has a thickness of 15mm, a door handle 122 is disposed on a side of the operating door panel 12 away from the hinge point, the door handle 122 carries a signal to detect the open or closed state of the operating door panel 12, and an airtight process is also required between the door handle 122 and the outer shield body 11.

Example two

On the basis of the first embodiment, the second embodiment further provides a double-layer closed isolating device for a granulator, which includes the sealing structure as described above, wherein the sealing structure is the same as that of the first embodiment, and is not described herein again.

In order to realize ventilation of the outer isolation chamber, a fresh air processing system 4 and an exhaust air processing system 5 are installed at the top of the outer isolation cover main body 11, the fresh air processing system 4 is used for providing clean air into the outer isolation chamber, and the exhaust air processing system 5 is used for providing negative pressure guarantee for the outer isolation chamber; the fresh air processing system 4 comprises a fresh air pneumatic valve 41 penetrating through the top wall of the outer isolation cover main body 11, a fresh air filter 42 installed at the bottom of the fresh air pneumatic valve 41 and an air compression pneumatic valve 43 installed at one side of the top of the fresh air pneumatic valve 41, wherein the fresh air filter 42 processes clean air introduced into the outer isolation chamber, and the fresh air entering the outer isolation chamber is adjusted by controlling the opening angle of the fresh air pneumatic valve 41, so that the temperature and the pressure difference of the whole system are ensured to be within a controllable range; the exhaust air processing system 5 comprises a plurality of exhaust sleeves 51 penetrating through the top wall of the outer isolation cover main body 11, an exhaust filter 52 and a total exhaust pipe 53, wherein the exhaust filter 52 is arranged in each exhaust sleeve 51, and the air exhausted from the outer isolation chamber can be processed by the arrangement of the exhaust filter 52 as the medicines produced in the inner isolation chamber and the outer isolation chamber are high-activity medicines; the exhaust sleeve 51 is positioned above the inner isolation hood main body 21; each exhaust sleeve 51 is respectively communicated with the main exhaust pipe 53; wherein the air passes through the fresh air pneumatic valve 41 to enter the interior of the outer isolation hood main body 11 and passes through the main exhaust pipe 53 to be exhausted.

In this embodiment, the top of the outer shield body 11 is further provided with a temperature and humidity detection assembly 6 and a pressure difference detection assembly 7, and the pressure difference detection assembly 7 comprises five digital pressure difference meters for sequentially detecting the pressure difference of the fresh air filter 42 and the 4 exhaust air filters 52, so as to ensure the filtering efficiency of the whole system; temperature and humidity detection assembly 6 provides temperature and humidity detection for the outer isolation chamber.

In order to convey the medicine into the inner isolation chamber, a feed valve 8 is further installed at the top of the outer isolation cover main body 11, a conveyor 81 communicated with the feed valve 8 is installed inside the outer isolation cover main body 11, the conveyor 81 is communicated with the inner isolation cover main body 21, after the feed valve 8 is opened, the medicine is conveyed into the inner isolation cover main body 21 through the conveyor 81, and the conveyor 81 adopts a spiral feeding mode; and a continuous bag assembly 9 at the side wall of the outer shield body 11, the continuous bag assembly 9 being used for the transfer of samples and waste.

In light of the foregoing description of the preferred embodiment of the present invention, it is to be understood that various changes and modifications may be made by one skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.