阅读说明：本技术 包含n-(1,3,4-噁二唑-2-基)芳基甲酰胺类化合物的除草组合物及其应用 (Herbicidal compositions comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides and their use ) 是由 彭学岗 张景远 赵德 崔琦 于 2020-09-11 设计创作，主要内容包括：本发明属于农药领域,具体涉及一种包含N-(1,3,4-噁二唑-2-基)芳基甲酰胺类化合物的除草组合物及其应用。所述组合物包括除草有效量的活性成分A和活性成分B,其中,活性成分A为或其盐；活性成分B选自以下化合物及其盐/酯中的一种或多种：HPPD抑制剂、PDS抑制剂、DOXP抑制剂、ALS抑制剂、ACCase抑制剂、PPO抑制剂、PSII抑制剂、微管组装抑制剂等。该组合物能有效防除作物田中的异型莎草、碎米莎草、萤蔺等莎草科杂草,稻稗、马唐、稗草、千金子等禾本科杂草,以及鸭舌草、野慈姑、丁香蓼、泽泻等阔叶杂草问题,具有扩大杀草谱、减少施用量、能够产生增效作用并解决抗性杂草等特点。(The invention belongs to the field of pesticides, and particularly relates to a weeding composition containing an N- (1,3, 4-oxadiazole-2-yl) aryl formamide compound and application thereof. The composition comprises an active ingredient A and an active ingredient B with herbicidally effective amounts, wherein the active ingredient A is)

1.A herbicidal composition comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides, which comprises a herbicidally effective amount of an active ingredient A and an active ingredient B, wherein,

the active ingredient A isOr a salt thereof;

the active ingredient B is selected from one or more of the following compounds and salts/esters thereof:

(1) HPPD inhibitors: sulcotrione, mesotrione, topramezone, tembotrione, fluroxypyr, mesotrione, bicyclosulfuron, topramezone, trazodone, triazophone, topramezone, pyrazote, pyraflutole, tolpyralate, fenquinotrione, isoxaflutole, pyraclonil, fenflurazone, topramezone,

(2) (ii) a PDS inhibitor: flurtamone, diflufenican, beflubutamid, fluroxypyr and fluridone;

(3) a DOXP inhibitor: clomazone, bixlazone;

(4) ALS inhibitors: tribenuron-methyl, thifensulfuron-methyl, bensulfuron-methyl, pyrazosulfuron-ethyl, thiencsulfuron-methyl, halosulfuron-methyl, propyrisulfuron-methyl, metrisulfuron-methyl, rimsulfuron-methyl, flucarbazone-methyl, mesosulfuron-methyl, nicosulfuron-methyl, foramsulfuron-methyl, flumetsulam-methyl, triasulfuron-methyl, fluazincarbazide-methyl, penoxsulam-methyl, cloransulam-methyl, pyroxsulam-methyl, imazamox, imazethapyr, imazapyr, pyriminobac-methyl, florasulam, pyribenzoxim-methyl, propbensulfuron-methyl, imazethapyr-methyl, chlorosulfuron, cinosulfuron, cyclosulfamuron, amidosulfuron, triasulfuron-methyl, tribenuron-methyl, iodosulfuron-methyl sodium, flazasulfuron-methyl, flucetosulfuron, metsulfuron-methyl, triflusulfuron-methyl, sulfosulfuron-methyl, pyrazosulfuron-methyl;

(5) ACCase inhibitors: clodinafop-propargyl, pinoxaden, clethodim, sethoxydim, quizalofop-p-ethyl, tralkoxydim, fluazifop-p-butyl, haloxyfop-methyl, diclofop-methyl, fenoxaprop-p-ethyl, cyhalofop-butyl, clethodim, metamifop, oxadiargyl;

(6) PPO inhibitors: oxyfluorfen, fomesafen, oxadiazon, oxadiargyl, sulfentrazone, pyraclonil, flumioxazin, pentoxazone, tiafenacil, saflufenacil, pyraflufen, carfentrazone-ethyl, butafenacil, trifluoromethoxyfen, triflumimoxazin, metribuzin, and ephedifenacil;

(7) PSII inhibitors: atrazine, prometryn, simetryn, terbuthylazine, terbutryn, ametryn, ipratron, fenfluryn, diquat, simazine, metribuzin, ethiprole, amicarbazone, metamitron, cyanazine, chlortoluron, isoproturon, diuron, fluometuron, linuron, buthiuron, sumuron, gluron, bromuron, glufosinate, pyridazinol, hexazinone, isoethazine, prodazine, bromacil, lenacil, triclopyr, thiuron, isoxauron, metoxuron, subtilon, trifluoxazine, cycloprozoximate, propanil, pyridate, desmetryn, bromoxynil octanoate, bromoxynil, ioxynil;

(8) microtubule assembly inhibitors: trifluralin, butralin, pendimethalin, dithiopyr, butyfluing, oryzalin, sulfluralin, flumetsulam, fenthizamide, natremit, chlorthal and butafosinate;

(9) microtubule combination inhibitors: diacyl urea;

(10) VLCFA inhibitors: acetochlor, butachlor, pretilachlor, metolachlor, mefenacet, s-metolachlor, flufenacet, napropamide, pyraflufen, anilofol, anilofos, xylfenamid, fentrazamide, triazolam, cafenstrole, mephos, metolachlor, propyzamide, dimethenamid, dimefluzamide, Fenoxasulfone;

(11) lipid synthesis (non-acetyl-coa carboxylase) inhibitors: prosulfocarb, molinate, prosulfocarb, furbengal, ethofumesate, triallate, dichlormate, dichlorvos, penflufen and penflufen;

(12) synthetic laserThe following elements: quinclorac, fluroxypyr, triclopyr, clopyralid, picloram, aminopyralid, dicamba, fluroxypyr, 2-methyl-4-chlorophenoxyacetic acid thioester, MCPB, 2-methyl-4-chlorophenoxypropionic acid, 2-methyl-4-sodium chlorophenoxyacetate, 2-methyl-4-chlorophenoxyacetic acid isooctyl ester, 2, 4-dichlorophenoxyacetic acid butyl ester, 2, 4-dichlorophenoxyacetic acid isooctyl ester, 2, 4-dichlorophenoxyacetic acid, chloroquinolinic acid, 2-methyl-4-chlorodimethylammonium salt, 2, 4-dichlorpropionic acid, 2, 4-dichlorbutanoic acid, benazolin, aminocyclopyrachlor, 2, 4-dichlorfenac acid,

(13) EPSPS inhibitors: glyphosate, phosphinothricin;

(14) a GS inhibitor: glufosinate, bialaphos, refined glufosinate;

(15) PSI inhibitor selected from paraquat, diquat;

(16) DHP inhibitors: asulam;

(17) cellulose synthesis inhibitors: triazinyl flufenacet, indexazine flufenacet;

(18) other herbicides: oxaziclomefone, cinmethylin, indanthrone, quinclomazone, cumyluron, tetflupyrlomet.

2. The weeding composition containing the N- (1,3, 4-oxadiazole-2-yl) aryl formamide compounds according to claim 1, wherein the weight ratio of A, B in the weeding composition is 1: 600-200: 1 and 1: 500-100: 1; preferably 1: 300-80: 1 and 1: 200-60: 1; more preferably 1:150 to 50:1 and 1:120 to 30: 1; further preferably 1: 100-20: 1 and 1: 80-15: 1; further preferred are 1:50 to 10:1, 1:30 to 5:1, 1:10 to 4:1 and 1:5 to 1: 1.

3.A herbicidal composition comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides according to claim 1 or 2, characterized in that the percentage by mass of a and B in the herbicidal composition is 1 to 95%, preferably 10 to 80% of the total.

4.A herbicidal composition comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides according to any one of claims 1 to 3, characterized in that conventional adjuvants are also included in the herbicidal composition.

5.A herbicidal composition comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides according to claim 4, characterized in that the conventional adjuvants include carriers or surfactants.

6. The herbicidal composition comprising an N- (1,3, 4-oxadiazol-2-yl) arylcarboxamide compound according to any one of claims 1 to 5, characterized in that the herbicidal composition further comprises at least one safener.

7.A herbicidal composition comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides according to claim 6, characterized in that the safener is selected from one or more of isoxadifen, cyprosulfamide, mefenpyr, cloquintocet, gibberellic acid, furilazole, mecamifen.

8. The herbicidal composition containing the N- (1,3, 4-oxadiazol-2-yl) arylcarboxamide compound according to any one of claims 1 to 7, characterized in that the specific formulation of the herbicidal composition is dispersible oil suspension, aqueous suspension, suspoemulsion, wettable powder, emulsifiable concentrate, water dispersible granules, aqueous emulsion or microemulsion.

9. Use of a herbicidal composition comprising an N- (1,3, 4-oxadiazol-2-yl) arylcarboxamide compound as claimed in any of claims 1 to 8 for controlling weeds.

10.A method for controlling unwanted plant growth, which comprises applying a herbicidal composition comprising an N- (1,3, 4-oxadiazol-2-yl) arylcarboxamide compound as claimed in any of claims 1 to 8 to a plant, to parts of a plant, to seeds of a plant or to the area where a plant is growing.

Technical Field

The invention belongs to the field of pesticides, and particularly relates to a weeding composition containing an N- (1,3, 4-oxadiazole-2-yl) aryl formamide compound and application thereof.

Background

Chemical weeding is the most economic and effective means in preventing and removing weeds in farmlands, but the problems of drug resistance and resistance evolution of weeds and the like are easily caused by using a single variety or a single action mode of chemical herbicide continuously at a high dose for a long time. The reasonable compounding or mixing of the herbicide compound has the advantages of expanding the weed spectrum, improving the control effect, delaying the occurrence and development of drug resistance and drug resistance of weeds and the like, and is one of the most effective methods for solving the problems. For example, patent CN103596946A discloses N- (1,3, 4-oxadiazole-2-yl) arylformamide and its use as herbicide, and there is still a need to develop a variety of herbicidal compositions with high safety, broad herbicidal spectrum, synergistic effect and capability of solving the problem of resistant weeds.

Disclosure of Invention

In order to solve the above problems in the prior art, the present invention provides a herbicidal composition comprising an N- (1,3, 4-oxadiazol-2-yl) arylcarboxamide compound and its use. The composition can effectively prevent and kill cyperaceae weeds such as cyperus rotundus, cyperus rotundus and irish rush, gramineae weeds such as barnyard grass, digitaria sanguinalis, barnyard grass and moleplant seed, and broadleaf weeds such as monochoria vaginalis, edible tulip, ludwigia prostrata and rhizoma alismatis in crop fields, and has the characteristics of expanding weed control spectrum, reducing application amount, generating synergistic effect, solving resistant weeds and the like.

A herbicidal composition comprising N- (1,3, 4-oxadiazol-2-yl) arylcarboxamides comprising a herbicidally effective amount of active ingredient A and active ingredient B, wherein,

the active ingredient A isOr a salt thereof;

the active ingredient B is selected from one or more of the following compounds and salts/esters thereof:

(1) HPPD inhibitors: sulcotrione (CAS number: 99105-77-8), mesotrione (CAS number: 104206-82-8), topramezone (CAS number: 210631-68-8), tembotrione (CAS number: 335104-84-2), fluroxypyr (CAS number: 352010-68-5), benzofuranone (CAS number: 473278-76-1), bicyclosulfulone (CAS number: 156963-66-5), diconazole (CAS number: 1622908-18-2), ciclopirox (CAS number: 1855929-45-1), triazophorione (CAS number: 1911613-97-2), benzoxaflutole (CAS number: 1992017-55-6), fenzopyr pyrazole (CAS number: 365400-11-9), pyrazolate (CAS number: 58011-68-0), pyroxadim (CAS number: 82692-44-2), tolpyrate (CAS number: 1101132-67-5), fenquinotrione (CAS number: 1342891-70-6), isoxaflutole (CAS number: 141112-29-0), penflufen (CAS number: 71561-11-0),

(2) (ii) a PDS inhibitor: flurtamone (CAS number: 61213-25-0), flurtamone (CAS number: 96525-23-4), diflufenican (CAS number: 83164-33-4), diflufenican (CAS number: 137641-05-5), beflubutamid (CAS number: 113614-08-7), norflurazon (CAS number: 27314-13-2), and fluridone (CAS number: 59756-60-4);

(3) a DOXP inhibitor: clomazone (CAS number: 81777-89-1), bixlozone (CAS number: 81777-95-9);

(4) ALS inhibitors: tribenuron-methyl (CAS number: 101200-48-0), thifensulfuron-methyl (CAS number: 79277-27-3), bensulfuron-methyl (CAS number: 83055-99-6), pyrazosulfuron-ethyl (CAS number: 93697-74-6), thiencarbazone-methyl (CAS number: 317815-83-1), halosulfuron-methyl (CAS number: 100784-20-1), propyrisulfuron (CAS number: 570415-88-2), metazosulfuron-methyl (CAS number: 868680-84-6), rimsulfuron-methyl (CAS number: 122931-48-0), ethoxysulfuron (CAS number: 126801-58-9), pyriminosulfuron-methyl (CAS number: 213464-77-8), flucarbazone-methyl (CAS number: 181274-17-9), mesosulfuron-methyl (CAS number: 208465-21-8), nicosulfuron (CAS number: 111991-09-4), Foramsulfuron (CAS number: 173159-57-4), flumetsulam (CAS number: 98967-40-9), triafamone (CAS number: 874195-61-6), penoxsulam (CAS number: 219714-96-2), cloransulam-methyl (CAS number: 147150-35-4), pyroxsulam (CAS number: 422556-08-9), imazamox (CAS number: 114311-32-9), imazapic (CAS number: 104098-48-8), imazethapyr (CAS number: 81385-77-5), imazapyr (CAS number: 81334-34-1), pyriminobac (CAS number: 147411-69-6), florasulam (CAS number: 145701-23-1), pyribenzoxim (CAS number: 135186-78-6), pyribenzoxim (CAS number: 168088-61-7), Tribenuron-methyl (CAS number: 145026-81-9), imazethapyr (CAS number: 81335-77-5), chlorsulfuron (CAS number: 64902-72-3), cinosulfuron (CAS number: 94593-91-6), cyclosulfamuron (CAS number: 136849-15-5), amidosulfuron (CAS number: 120923-37-7), triasulfuron (CAS number: 82097-50-5), iodosulfuron-methyl sodium salt (CAS number: 144550-36-7), flupyrsulfuron (CAS number: 144740-54-5), flucetosulfuron (CAS number: 412928-75-7), metsulfuron (CAS number: 74223-64-6), triflusulfuron (CAS number: 142469-14-5), sulfosulfuron (CAS number: 141776-32-1), pyrazosulfuron (CAS number: 122548-33-8), Bispyribac-sodium (CAS number: 125401-92-5), and sulfentrazone (CAS number: 139528-85-1);

(5) ACCase inhibitors: clodinafop-propargyl (CAS number: 105512-06-9), pinoxaden (CAS number: 243973-20-8), clethodim (CAS number: 99129-21-2), sethoxydim (CAS number: 74051-80-2), quizalofop-p-ethyl (CAS number: 100646-51-3), tralkoxydim (CAS number: 87820-88-0), fluazifop-p-butyl (CAS number: 69806-50-4), haloxyfop-R (CAS number: 72619-32-0), diclofop-p-methyl (CAS number: 51338-27-3), fenoxaprop-p-ethyl (CAS number: 113158-40-0), cyhalofop-butyl (CAS number: 122008-85-9), clethodim (CAS number: 139001-49-3), metamifop (CAS number: 256412-89-2), oxadiargyl (CAS number: 111479-05-1);

(6) PPO inhibitors: fluroxypyr ether (CAS number: 42874-03-3), fomesafen (CAS number: 72178-02-0), oxadiazon (CAS number: 19666-30-9), oxadiargyl (CAS number: 39807-15-3), sulfentrazone (CAS number: 122836-35-5), pyraclonil (CAS number: 158353-15-2), flumioxazin (CAS number: 103361-09-7), pentoxazone (CAS number: 110956-75-7), tiafenacil (CAS number: 1220411-29-9), saflufenacil (CAS number: 372137-35-4), pyraflufen (CAS number: 129630-19-9), carfentrazone (CAS number: 128621-72-7), butafenacil ester (CAS number: 134605-64-4), fluroxypyr ether ethyl ester (CAS number: 131086-42-5), Fluoroglycofen-ethyl (CAS number: 77501-60-1), fluoroglycofen-ethyl (CAS number: 50594-66-6), triflumimoxazin (CAS number: 1258836-72-4), fluazinam-methyl (CAS number: 117337-19-6), Epyrifenacin (CAS number: 353292-31-6);

(7) PSII inhibitors: atrazine (CAS number: 1912-24-9), prometryn (CAS number: 7287-19-6), simetryn (CAS number: 1014-70-6), terbuthylazine (CAS number: 5915-41-3), terbutryn (CAS number: 886-50-0), ametryn (CAS number: 834-12-8), ipratropium (CAS number: 4147-51-7), fenflurazine (CAS number: 845-52-3), prometryn (CAS number: 1014-69-3), simazine (CAS number: 122-34-9), metribuzin (CAS number: 87-21064-9), ethiprole (CAS number: 64529-56-2), amicarbazone (CAS number: 129909-90-6), metribuzin (CAS number: 41394-05-2), cyanazine (CAS number: 21725-46-2), Chlortoluron (CAS number: 15545-48-9), isoproturon (CAS number: 34123-59-6), diuron (CAS number: 330-54-1), fluometuron (CAS number: 2164-17-2), linuron (CAS number: 330-55-2), buthiuron (CAS number: 34014-18-1), cypermethron (CAS number: 42609-52-9), chlortoluron (CAS number: 1746-81-2), bromuron (CAS number: 3060-89-7), endothel (CAS number: 555-37-3), pyridazinol (CAS number: 40020-01-7), hexazinone (CAS number: 51235-04-2), isoethazine (CAS number: 22936-75-0), prodrazine (CAS number: 1912-26-1), bromacil (CAS number: 314-40-9), Cyclinadine (CAS number: 2164-08-1), terbacil (CAS number: 5902-51-2), methabenzthiazuron (CAS number: 18691-97-9), cyclosulfamuron (CAS number: 1982-49-6), isoxaben (CAS number: 55861-78-4), metoxuron (CAS number: 19937-59-8), cumuron (CAS number: 1982-47-4), trifluoxazine (CAS number: 1258836-72-4), cyclopyromate (CAS number: 499231-24-2), propanil (CAS number: 709-98-8), pyridate (CAS number: 55512-33-9), betalain (CAS number: 13684-56-5), betanin (CAS number: 13684-63-4), bentazone (CAS number: 25057-89-0), bromoxynil octanoate (CAS number: 1689-99-2), Bromoxynil (CAS number: 1689-84-5), ioxynil (CAS number: 1689-83-4);

(8) microtubule assembly inhibitors: trifluralin (CAS number: 1582-09-8), butralin (CAS number: 33629-47-9), pendimethalin (CAS number: 40487-42-1), dithiopyr (CAS number: 97886-45-8), ethambucil (CAS number: 55283-68-6), oryzalin (CAS number: 19044-88-3), flumetsulam (CAS number: 1861-40-1), thiabendazole (CAS number: 117718-60-2), propaquilate (CAS number: 23950-58-5), dichlorvos (CAS number: 1861-32-1) and phorate (CAS number: 36335-67-8);

(9) microtubule combination inhibitors: diacyl-amine (CAS number: 16118-49-3);

(10) VLCFA inhibitors: acetochlor (CAS number: 34256-82-1), butachlor (CAS number: 23184-66-9), pretilachlor (CAS number: 51218-49-6), metolachlor (CAS number: 87392-12-9), mefenacet (CAS number: 73250-68-7), s-metolachlor (CAS number: 178961-20-1), flufenacet (CAS number: 142459-58-3), alachlor (CAS number: 15299-99-7), pyriflufen (CAS number: 447399-55-5), anilofol (CAS number: 64249-01-0), xylenol oxamine (CAS number: 87674-68-8), fentrazamide (CAS number: 158237-07-1), triafamone (CAS number: 212201-70-2), cafenstrole (CAS number: 125306-83-4), Mepiquat chloride (CAS number: 24151-93-7), propisochlor (CAS number: 86763-47-5), alachlor (CAS number: 15972-60-8), diflufenican (CAS number: 67129-08-2), propachlor (CAS number: 1918-16-7), dimethenamid (CAS number: 106700-29-2), Dimesulfazet (CAS number: 1215111-77-5), Fenoxasulfone (CAS number: 639826-16-7);

(11) lipid synthesis (non-acetyl-coa carboxylase) inhibitors: prosulfocarb (CAS number: 52888-80-9), molinate (CAS number: 2212-67-1), prosulfocarb (CAS number: 28249-77-6), benfuresate (CAS number: 68505-69-1), ethofumesate (CAS number: 26225-79-6), triallate (CAS number: 2303-17-5), dichlorfon (CAS number: 1929-77-7), butamolide (CAS number: 2008-41-5), dichlorfon (CAS number: 1134-23-2), pennisetum (CAS number: 61432-55-1) and penflun (CAS number: 85785-20-2);

(12) synthesis of hormones: quinclorac (CAS number: 84087-01-4), fluroxypyr (CAS number: 69377-81-7), fluroxypyr-meptyl (CAS number: 81406-37-3), fluroxypyr (CAS number: 943831-98-9), triclopyr (CAS number: 55335-06-3), clopyralid (CAS number: 1702-17-6), picloram (CAS number: 1918-02-1), aminopyralid (CAS number: 150114-71-9), dicamba (CAS number: 1918-00-9), fluroxypyr (CAS number: 1390661-72-9), 2-methyl-4-chlorophenoxyacetic acid (CAS number: 94-74-6), 2-methyl-4-chloro-phenothiolester (CAS number: 25319-90-8), MCPB (CAS number: 94-81-5), 2-methyl-4-chlorophenoxypropionic acid (CAS number: 93-65-2), sodium 2-methyl-4-chlorophenoxyacetate (CAS number: 3653-48-3),Isooctyl 2-methyl-4-chlorophenoxyacetate (CAS number: 29450-45-1), butyl 2, 4-dichlorophenoxyacetate (CAS number: 94-80-4), isooctyl 2, 4-dichlorophenoxyacetate (CAS number: 25168-26-7), 2, 4-dichlorophenoxyacetic acid (CAS number: 94-75-7), chloroquinolinic acid (CAS number: 90717-03-6), 2-methyl-4-chlorodimethylammonium salt (CAS number: 2039-46-5), 2, 4-dichlorpropionic acid (CAS number: 120-36-5), 2, 4-dichlorbutanoic acid (CAS number: 94-82-6), benazolin (CAS number: 25059-80-7), cyprodinil (CAS number: 858956-08-8), CAS,

(13) EPSPS inhibitors: glyphosate (CAS number: 1071-83-6), phosphinothricin (CAS number: 81591-81-3);

(14) a GS inhibitor: glufosinate-ammonium (CAS number: 77182-82-2), bialaphos (CAS number: 35597-43-4), and glufosinate-ammonium (CAS number: 35597-44-5);

(15) PSI inhibitors paraquat (CAS number: 1910-42-5), diquat (CAS number: 6385-62-2);

(16) DHP inhibitors: asulam (CAS number: 3337-71-1);

(17) cellulose synthesis inhibitors: triazinyl flumioxazin (CAS number: 131475-57-5), indexazin (CAS number: 950782-86-2);

(18) other herbicides: oxaziclomefone (CAS number: 153197-14-9), cinmethylin (CAS number: 87818-31-3), indanthrone (CAS number: 133220-30-1), quinclorac (CAS number: 130901-36-8), quintocet (CAS number: 1639426-14-4), prosulfuron (CAS number: 99485-76-4), imazalone (CAS number: 150-68-5), tetflupyrlomet (CAS number: 2053901-33-8).

In the context of the present specification, if the abbreviated forms of the common name of the active compounds are used, all customary derivatives, such as esters and salts, and also isomers, in particular optical isomers, in particular one or more commercially available forms, are included in each case. If the generic name denotes esters or salts, all other customary derivatives, such as other esters and salts, free acids and neutral compounds, and also isomers, in particular optical isomers, in particular one or more commercially available forms, are also included in each case. The chemical name given for a compound means at least one compound covered by the generic name, with compounds generally being preferred. In the case of sulfonamides, such as sulfonylureas, salts also include those formed by exchange of cations with hydrogen atoms in the sulfonamide group. For example, 2-methyl-4-chloro derivatives include, but are not limited to: 2 methyl 4 chloro sodium salt, potassium salt, dimethyl ammonium salt, isopropyl amine salt, etc., and 2 methyl 4 chloromethyl ester, ethyl ester, isooctyl ester, ethyl thioester, etc.; 2,4-D derivatives include, but are not limited to: 2,4-D salts such as sodium salt, potassium salt, dimethylammonium salt, triethanolamine salt, isopropylamine salt, choline and the like, and 2,4-D esters such as methyl ester, ethyl ester, butyl ester, isooctyl ester and the like.

Wherein the A, B weight ratio is 1: 600-200: 1 and 1: 500-100: 1; preferably 1: 300-80: 1 and 1: 200-60: 1; more preferably 1:150 to 50:1 and 1:120 to 30: 1; further preferably 1: 100-20: 1 and 1: 80-15: 1; further preferred are 1:50 to 10:1, 1:30 to 5:1, 1:10 to 4:1 and 1:5 to 1: 1.

In one embodiment, the invention also lists the following specific combinations of component a and component B:

in another embodiment, each of the components A in the above tables is replaced by a corresponding salt.

In the context of the present invention, the salts of the compounds are preferably in the form of the respective alkali metal, alkaline earth metal or ammonium salts (e.g. dimethylammonium, triethanolammonium, isopropylamine, choline etc.), preferably in the form of the respective alkali metal salts, more preferably in the form of the respective sodium or potassium salts, most preferably in the form of the respective sodium salts.

The mass percentage of A, B in the weeding composition accounts for 1-95% of the total amount, and preferably 10-80%.

The weeding composition also comprises conventional auxiliaries which comprise a carrier and a surfactant.

The term "carrier" herein denotes an organic or inorganic, natural or synthetic substance. They facilitate the application of the active ingredient, the carrier being generally inert and must be agriculturally acceptable, in particular for the treated plant. The carrier may be a solid, such as a clay, natural or synthetic silicate, silica, resin, wax, solid fertilizer, or the like; or liquids such as water, alcohols, ketones, petroleum distillates, aromatic or waxy hydrocarbons, chlorinated hydrocarbons, liquefied gases, etc.

Surfactants may include emulsifying, dispersing or wetting agents, which may be ionic or non-ionic. Examples which may be mentioned are salts of polyacrylic acids, lignosulphonates, salts of phenolsulphonic or naphthalenesulphonic acids, polymers of ethylene oxide with aliphatic alcohols or with aliphatic acids or with aliphatic amines and substituted phenols, in particular alkylphenols or arylphenols, sulphosuccinates, taurine derivatives, in particular taurine alkyl esters, and phosphoric esters of alcohols or polyhydroxyethylated phenols, alkylsulfonates, alkylarylsulphonates, alkylsulfates, lauryl ether sulphates, fatty alcohol sulphates, and sulphated hexadec, heptadeca-and octadecanols and sulphated fatty alcohol glycol ethers, and furthermore condensates of naphthalene or naphthalenesulphonic acids with phenol and formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenol, octylphenol or nonylphenol, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ether, tristearylphenyl polyglycol ether, polystearylphenyl polyglycol ether, Alkylaryl polyether alcohols, alcohol and fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignosulfite waste liquors, and also proteins, denatured proteins, polysaccharides (e.g. methylcellulose), hydrophobically modified starches, polyvinyl alcohols, polycarboxylates, polyalkoxylates, polyvinylamines, polyvinylpyrrolidone and copolymers thereof. At least one surfactant is required to be present to facilitate dispersion of the active ingredients in water and to facilitate their proper application to the plant.

The compositions may also contain various other components such as protective colloids, binders, thickeners, thixotropic agents, penetrants, stabilizers, chelating agents, dyes, colorants, and polymers.

In addition, the composition of the present invention can be mixed with the following active substances, for example, known substances in "the world Wide Specification of New agricultural chemical products", the Chinese agricultural science and technology Press, 2010.9 and the references cited therein. For example, herbicidal active substances mentioned below (remarks: the name of the compound, or the generic name according to the International organization for standardization (ISO), or the chemical name, when appropriate with a code), acetochlor, butachlor, alachlor, propisochlor, metolachlor, s-metolachlor, pretilachlor, propachlor, butachlor, napropamide, R-laevo-napropamide, propanil, mefenacet, diphenoyl-oxamide, diflufenican, flumetsulam, bebutamid, dimethenamid, ethoxybenclamide, flufenacet, methoxyfenacet, metazachlor, isooxachlor, lofluvalinate, dimethenamid, butachlor, propisochlor, mefenamid, flucetochlor, propyzamide, dimethenamid, Terbutamid, dimethenamid, dimethachlor, norfluramine, trifoliamine, chlorantraniliprole, propyzamide, penflufen, napropamide, acetometazachlor, naproxen, fenacet, pyraflufen, metolachlor, clofenamide, butachlor, butamidin, fluazinam, atrazine, simazine, prometryn, cyanazine, simetryn, ametryn, prometryn, ipretryn, fluroxypyr, terbutryn, terbutazine, triazineon, cyhalofop, ganciclovir, prometryn, simazine, triazazine, dimethametrazine, isopentetryn, cycloprozine, terbutryn, sec-butyn, terbutaline, terbutryn, metolachlor, cyhalofop, metolachlor, prometryn, simazine, atrazine, dimethametryn, dimethametin, terbutryn, metolachlor, dimethachlor, dimethozin, atrazine, metolachloraz, metolachlor, metolac, Cyanuric acid, Indaziflam, chlorsulfuron, metsulfuron, bensulfuron-methyl, chlorimuron-ethyl, tribenuron-methyl, thifensulfuron-methyl, pyrazosulfuron-ethyl, mesosulfuron-methyl, iodosulfuron-methyl sodium, formamidosulfuron, cinosulfuron, triasulfuron, sulfometuron-methyl, nicosulfuron, ethametsulfuron-methyl, amidosulfuron, ethoxysulfuron, cyclosulfamuron-methyl, rimsulfuron, azimsulfuron-methyl, monosulfuron-methyl, primisulfuron-methyl, flusulfuron-methyl, flazasulfuron-methyl, propsulfuron-methyl, prosulfuron-methyl, trifloxysulfuron, triflusulfuron-methyl, metsulfuron-methyl, primisulfuron-methyl, propulsulfuron-methyl, propaferon-methyl, triflusulfuron-methyl, sulfometuron-methyl, pyrisulfuron-methyl, propalis-ethyl, thiuron-methyl, sulfometuron-methyl, sulfometuron-ethyl, sulfometuron-ethyl, sulfofluridone, sulfometuron-ethyl, sulfofluridone, sulfometuron, sulfo, Dicumyl ether, aclonifen, ethoxyfen-ethyl, bifenox, trifluoromethoxyfen, metoxyfen, trifluornitrofen, fluoroglycofen, fluridone, bifenox, dimethofen, fluazifop-butyl, Halosafen, chlortoluron, isoproturon, linuron, diuron, fenpropuron, fluometuron, methabenzthiazuron, benzuron, sulfosulfuron, clofenuron, tebuthiuron, clodinuron, meturon, metoxuron, bromuron, metoxuron, meturon, metoxuron, metoron, Betalain, asulam, tefurazol, avenacalin, anilazine, chlorpropham, dichlofenamate, imazalil, cloropham, Carboxazole, chlorerprocarb, Fenasulam, BCPC, CPPC, Carbasulam, buticarb, thiobencarb, dimethenate, triallate, dichloropetalum, ethiofen, prosulfocarb, cloquintocet, prosulfocarb, dichloropetalum, dichloropetalate, dichloropetal, 2-methyl-4-chloropropionate, 2-methyl-4-chlorobutyric acid, 2,4, 5-nasal discharge propionic acid, 2,4, 5-nasal discharge butyric acid, 2-methyl-4-chloroamine salt, dicamba, woollen boom, varparvax, cypress, triclosan, dichlorfenamic acid, metoclopramide, diclofop-p-ethyl, haloxyfop-methyl, haloxyfop-ethyl, quizalofop-p-ethyl, fenoxaprop-p-ethyl, cyhalofop-butyl, fenoxaprop-p-ethyl, cloroph-ethyl, haloxyfop-ethyl, trifoliate-ethyl, clomazone, paraquat, dixyl, asulam, flutolon, isoproturon, chlorothalofop-ethyl, cyhalofop-p-ethyl, propafen-ethyl, butyfen-ethyl, fluroxypyr, metalaxyl, propafen, propaferin, propafen, glyphosate, anilofos, glufosinate, sulfosate, piperaphos, bialaphos, bensulide, imazapyr, mepyrazine, varroa, amifostine, glufosinate, imazethapyr ammonium salt, imazethapyr, imazamethabenz ester, fluroxypyr, isooctyl fluroxypyr, clopyralid, picloram, triclopyr, dithiopyr, haloxyfen, triclopyr, thiazopyr, flurazinone, aminopyralid, flurazone, diflufenzopyr, butoxyethyl triclopyr, ciodinate, sethoxydim, clethodim, thiacet, sethoxydim, clethodim, carfenflurazone, buthiazole, metribuzin, carfenflurazone, metamitron, fenflurazone, fenpyr, benzone, iodoxynil, bromoxynil, isoflurazone, isofluroxypyr, bensulam, isofluroxypyr, clomazone, ioxynil, dichlobenil, tolfenacet, pyraclonil, Iodobonil, flumetsulam, florasulam, penoxsulam, sulfentrazone, cloransulam, diclosulam, pyroxsulam, fluralin, bispyribac, pyribenzoxim, pyriminobac-methyl, pyrithiobac-methyl, bicyclosulfuron, mesotrione, Tembotrione, Tefuryltrione, Bicyclopyrone, ketoxydipradox, isoxaflutole, fenoxasulfolane, Methiozolin, isopyrafen, pyraflufen, pyraflutole, pyrazotocide, pyraclonil, pyraclofenacetone, flumetsulcotrione, flumetsulam, fenflurazole, fentrazachlor, amicarbazone, fentrazachlor, pyrazachlor, pyraclonil, flumicloram, flumioxazone, fenflurazole, flumicloram, bexapyroxadim, flumicloram, bexadim, flumicloram, benfluroram, flumicl, Phthalidyl ether, Flumezin, pentachlorophenol (sodium), dinol, terbenol, terbutal, pendimethalin, dinitrophenol, chloronitrophenol, dimethomorph, oxadiargyl, oxadiazon, pentoxazone, flumetsulam, mefenoxaprop-p-ethyl, tetrazolyl amine, fluridazin, oxamyl, bromamine, dimethenamid, pyridaben, pyridate, pyrirfalol, quinclorac, bentazone, pyridate, oxaziclorac, benazolin, clomazone, clomeptyl, isoprox, iprodione, propamocarb, cumylfen, indoxacarb, sodium chlorate, dalton, dalapon, trichloroacetic acid, monochloroacetone, hexachloroacetone, tetrafluoropropionic acid, pasture, bromophenol oxime, triazoxide, fentrazol, furamethon, fursulam, ethon, benfurazolin, pyrimethanil, clorac, clodinafop, clorac, cumquat, cumarone, clorac, Thidiazuron, alantin, hydroxybenone, metophenone, saflufenacil, dichlorophosphoric, trichloropropionic acid, Alorac, Diethamquat, Etnipromid, Iphridam, Ipfancarbazone, Thiencarbazone-methyl, Pyrimisulfan, Chlorflurflurazone, Tripropindan, Sulglycapin, Sumbelanoline, Campandichlor, Cytopyrimidic acid, thiocyananilide, clethodim, fenclorim, cloquintocet, mequintocet, oxaziclomex, oxabetrinil, pyroxaglim, furazolidone, imazaquin, isoxadifen, dichlormid, halauxin, halauxifen, DOWF, UBH-509, D489, LS 82-556, KPP-300, NC-324, NC-330, KH-218, DPX-N8189, SC-0744, DOWCO535, DK-8910, V-53482, PP-600, MBH-001, KIH-9201, ET-751, KIH-6127 and KIH-2023.

The herbicidal composition further comprises at least one safener selected from the group consisting of:

a) dichlorophenyl pyrazoline-3-carboxylic acid (S1) compounds, preferred compounds are, for example, ethyl 1- (2, 4-dichlorophenyl) -5- (ethoxycarbonyl) -5-methyl-2-pyrazoline-3-carboxylate (S1-1 mefenpyr-diethyl, PM, p. 594-595), and related compounds described, for example, in WO91/07874 and PM (p. 594-595).

b) Dichlorophenyl pyrazole carboxylic acid derivatives, preferred compounds are, for example, ethyl 1- (2, 4-dichlorophenyl) -5-methylpyrazole-3-carboxylate (S1-2), ethyl 1- (2, 4-dichlorophenyl) -5-isopropylpyrazole-3-carboxylate (S1-3), ethyl 1- (2, 4-dichlorophenyl) -5- (1, 1-dimethyl-ethyl) pyrazole-3-carboxylate (S1-4), ethyl 1- (2, 4-dichlorophenyl) -5-phenylpyrazole-3-carboxylate (S1-5), and related compounds as described in EP-A-333131 and EP-A-269806.

c) Triazole carboxylic acids (S1) and preferred compounds are, for example, fenchlorazole (fenchlorazole), i.e. ethyl 1- (2, 4-dichlorophenyl) -5-trichloromethyl- (1H) -1,2, 4-triazole-3-carboxylate (S1-6) and related compounds (see EP-A-174562 and EP-A-346620).

d) 5-benzyl-or 5-phenyl-2-isoxazoline-3-carboxylic acids or 5, 5-diphenyl-2-isoxazoline-3-carboxylic acids, preferred compounds being, for example, ethyl 5- (2, 4-dichlorobenzyl) -2-isoxazoline-3-carboxylate (S1-7) or ethyl 5-phenyl-2-isoxazoline-3-carboxylate (S1-8) and related compounds described in WO91/08202, or ethyl 5, 5-diphenyl-2-isoxazoline-3-carboxylate (S1-9, isoxadifen-ethyl)) or 5 described in the patent application (WO-A-95/07897), n-propyl 5-diphenyl-2-isoxazoline-3-carboxylate (S1-10) or ethyl 5- (4-fluorophenyl) -5-phenyl-2-isoxazoline-3-carboxylate (S1-11).

e) 8-Quinolinyloxyacetic acids (S2) of the class of compounds, preferably 1-methylhexan-1-yl (5-chloro-8-quinolinyloxy) acetate (S2-1, cloquintocet-mexyl), such as PM (p. 195-), (1, 3-dimethylbut-1-yl) (5-chloro-8-quinolinyloxy) acetate (S2-2), 4-allyloxybutyl (5-chloro-8-quinolinyloxy) acetate (S2-3), 1-allyloxypropan-2-yl (5-chloro-8-quinolinyloxy) acetate (S2-4), (ethyl 5-chloro-8-quinolinyloxy) acetate (S2-5), (methyl 5-chloro-8-quinolinyloxy) acetate (S2-6), allyl (5-chloro-8-quinolinyloxy) acetate (S2-7), 2- (2-propyleneiminoyloxy) -1-ethyl (5-chloro-8-quinolinyloxy) acetate (S2-8), 2-oxopropan-1-yl (5-chloro-8-quinolinyloxy) acetate (S2-9), and related compounds described in EP-A-86750, EP-A-94349 and EP-A-191736 or EP-A-0492366.

f) (5-chloro-8-quinolinoxy) propanedioic acid-based compounds, preferred compounds are, for example, diethyl (5-chloro-8-quinolinoxy) malonate, (diallyl (5-chloro-8-quinolinoxy) malonate, (methylethyl (5-chloro-8-quinolinoxy) -malonate and related compounds described in EP-A-0582198.

g) Phenoxyacetic acid, phenoxypropionic acid or aromatic carboxylic acids, such as 2, 4-dichlorophenoxyacetic acid (and esters) (2,4-D), 4-chloro-2-methylphenoxypropionate (2-methyl-4-chloropropionic acid (mecoprop)), MCPA or 3, 6-dichloro-2-methoxybenzoic acid (and esters) (dicamba).

h) Pyrimidines, such as fenclorim (PM, page 386-387) (═ 4, 6-dichloro-2-phenylpyrimidine),

i) dichloroacetamide-based active compounds, which are frequently used as pre-emergence safeners (soil-working safeners), for example "dichloroallylamine (dichlormid)" (PM, page 270-271) (═ N, N-diallyl-2, 2-dichloroacetamide), "AR-29148" (-3-dichloroacetyl-2, 2, 5-trimethyl-1, 3-oxazolidinone from Stauffer), "benoxacor" (PM, page 74-75) (-4-dichloroacetyl-3, 4-dihydro-3-methyl-2H-1, 4-benzoxazine), "APPG-1292" (-N-allyl-N [ (1, 3-dioxolan-2-yl) -methyl ] dichloroacetamide, from PPG Industries), "ADK-24" (═ N-allyl-N- [ (allylaminocarbonyl) -methyl ] -dichloroacetamide, from Sagro-Chem), "AAD-67" or "AMON 4660" (═ 3-dichloroacetyl-1-oxa-3-aza-spiro [4,5] decane, from nitrkemia or Monsanto), "diclonon" or "ABAS 145138" or "ala b 145138" (═ 3-dichloroacetyl-2, 5, 5-trimethyl-1, 3-diazabicyclo [4.3.0] nonane, from BASF), and "furilazol" or "AMON 13900" (see PM, 482-483) ((RS) -3-dichloroacetyl-5- (2-furyl) -2, 2-dimethyloxazolidinone),

j) dichloroacetone derivative-based active compounds, for example, "AMG 191" (CAS registry No. 96420-72-3) (═ 2-dichloromethyl-2-methyl-1, 3-dioxolane, available from Nitrokemia),

k) oxyimino compounds as active compounds, which are referred to as seed dressing materials, for example "oxabetrinil" (PM, page 689) (═ Z) -1, 3-dioxolan-2-ylmethoxyimino (phenyl) acetonitrile), which in seed dressing is referred to as safener in order to prevent damage to metolachlor (metallachlor), "fluoroxyfen" (PM, page 467 468) (═ 1- (4-chlorophenyl) -2,2, 2-trifluoro-1-ethanone O- (1, 3-dioxolan-2-ylmethyl) -oxime, which in seed dressing is referred to as safener in order to prevent damage to metolachlor (metallachlor), and "cyanohydrin" or "a-CGA-43089" (PM, page 983) ((Z) -cyanomethoxyimino (phenyl) acetonitrile), which is called safener in seed dressing, to prevent the damage of metolachlor (metolachlor),

l) Thiazolecarboxylic acid ester active compounds, which are known as seed dressing materials, for example "flurazon" (PM, p. 450. 451), (-2-chloro-4-trifluoromethyl-1, 3-thiazole-5-carboxylic acid benzyl ester), which are known as safeners in seed dressing to prevent damage to alachlor (alachlor) and metolachlor,

m) active compounds of the naphthalenedicarboxylic acid derivative class, which are known as seed dressings, for example "naphthalic anhydride" (PM, pp 1009-1010) (═ 1, 8-naphthalic anhydride), which are known as safeners in corn seed dressings to prevent damage to thiocarbamate herbicides,

n) chromanoic acid derivatives such as "ACL 304415" (CAS registry No. 31541-57-8) (═ 2-84-carboxychroman-4-yl) acetic acid available from american cyanamid),

o) active compounds which, in addition to herbicidal action on harmful plants, also have safener action on plants, for example "penetryn (dimerate)" or "AMY-93" (PM, p.302-303) (═ S-1-methyl-1-phenylethylpiperidine-1-thiocarboxylate), "diuron (daimuron)" or "ASK 23" (PM, p.247) (═ 1- (1-methyl-1-phenylethyl) -3-p-tolylureｃA), "cumyluron (cumyluron)", "jc-940" ((3- (2-chlorophenylmethyl) -1- (1-methyl-1-phenyl-ethyl) ureｃA, see JP- ｃA-60087254), "benzophenone (methoxyphenon)" or "ANK 049" (═ 3,3' -dimethyl-4-methoxy-benzophenone), "CSB" (═ 1-bromo-4- (chloromethylsulfonyl) benzene) (CAS registry No. 54091-06-4, available from Kumiai).

The safener is preferably one or more of isoxadifen (CAS: 163520-33-0), cyprosulfamide (CAS: 221667-31-8), mefenpyr (CAS: 135590-91-9), cloquintocet (CAS: 99607-70-2), gibberellic acid (CAS: 7-06-5), furilazole (CAS: 121776-33-8) and metacamifen (CAS: 129531-12-0).

The compositions of the present invention may be diluted or used directly by the user prior to use. The formulation can be prepared by conventional processing methods, i.e., mixing the active substance with a liquid solvent or solid carrier, and adding one or more surfactants such as dispersants, stabilizers, wetting agents, binders, defoamers, etc.

The specific preparation of the weeding composition is dispersible oil suspending agent, water suspending agent, suspending emulsion, wettable powder, missible oil, water dispersible granule (dry suspending agent), emulsion in water and microemulsion.

In short, the compositions of the present invention may be mixed with solid and liquid additives conventionally used in prior art formulations. The amount of the effective ingredient to be used varies depending on external conditions such as temperature, humidity, the nature of the herbicide to be used, and the like. It may vary widely, for example between 0.001 and 1.0kg/ha, or more of active substance, but preferably between 0.005 and 750g/ha, in particular between 0.005 and 500 g/ha.

The invention also provides an application of the weeding composition in weed control; and to provide a method of controlling unwanted plant growth comprising applying the herbicidal composition to a plant, part of a plant, plant seed, or area where a plant is growing.

In addition, the compositions according to the invention can be applied by spraying to the foliage of the plants to be treated, i.e. to the weeds, in particular to surfaces infested or susceptible to infestation by weeds.

When the herbicidal composition of the present invention is applied, an unexpected synergistic effect is obtained, and the herbicidal activity is more remarkable than the expected sum of the activities using individual herbicides, and the activities of the individual herbicides. The synergistic effect is manifested by reduced application rates, a broader spectrum of weed control, and a faster and longer lasting herbicidal action, which are desirable in the practice of weed control. These new compositions are clearly superior to existing herbicides in terms of the properties described, achieving reduced use and being more environmentally friendly.

The synergistic herbicidal composition of the invention also has the following advantages:

(1) the composition of the invention is environment-friendly and is easy to degrade in the environment.

(2) The weeding composition has low cost and convenient use, and has great economic and social benefits when being popularized and applied.

Detailed Description

The following examples are not intended to limit the invention, but merely to illustrate how the invention may be carried out. These examples show particularly significant effectiveness against certain weeds. Examples are as follows:

A) examples of the embodiments

Dispersible oil-suspension concentrate of A1+ mesotrione (4+ 1: representing 4% A1+ 1% mesotrione, the same applies hereinafter)

A1+ mesotrione + 0.3% citric acid + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ topramezone (3+1)

A1+ topramezone + 5% calcium dodecyl benzene sulfonate + 6% fatty alcohol-polyoxyethylene ether + 8% cardanol-oxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ topramezone (3+1)

A1+ carfentrazone-ethyl + 0.2% citric acid + 5% calcium dodecylbenzene sulfonate + 6% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

A1+ benzoxaflutole (4+4) dispersible oil suspending agent

A1+ benzoxaflutole + 5% calcium dodecylbenzenesulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% cardanol-oxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

A1+ isoxaflutole (4+4) dispersible oil suspending agent

A1+ isoxaflutole + 0.2% citric acid + 5% calcium dodecylbenzenesulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-oxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ clomazone (4+4)

A1+ clomazone + 4% calcium dodecylbenzene sulfonate + 6% cardanol polyoxyethylene ether + 8% castor oil polyoxyethylene ether + 2.5% organobentonite + 5% 100# solvent oil + methyl oleate

A1+ pyrazosulfuron-ethyl (4+2) dispersible oil suspending agent

A1+ pyrazosulfuron-ethyl, 0.5% urea, 5% calcium dodecylbenzenesulfonate, 8% fatty alcohol-polyoxyethylene ether, 5% castor oil-polyoxyethylene ether, 2.5% organobentonite, 2% fumed silica, 5% 100# solvent oil and methyl oleate

8, A1+ penoxsulam (4+1) dispersible oil suspending agent

A1+ penoxsulam + 5% calcium dodecylbenzene sulfonate + 6% sorbitan monooleate polyoxyethylene ether + 5% castor oil oxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

Dispersible oil suspending agent of A1+ imazamox (4+1)

A1+ metoclopramide, 5% calcium dodecyl benzene sulfonate, 8% fatty alcohol-polyoxyethylene ether, 6% cardanol-oxyethylene ether, 2.5% organobentonite, 2% fumed silica, 5% 100# solvent oil and methyl oleate

Dispersible oil suspension agent containing A1 and mebendazole nicotinic acid (4+1)

A1+ mebendazole nicotinic acid + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% cardanol-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ bispyribac-sodium (4+1)

A1+ Bispyribac-sodium, 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 5% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

12, A1+ clethodim (4+2) dispersible oil suspending agent

A1+ clethodim + 5% calcium dodecylbenzene sulfonate + 8% sorbitan monooleate polyoxyethylene ether + 6% castor oil polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 20% 100# solvent oil + methyl oleate

A1+ sethoxydim (4+2) dispersible oil suspension

A1+ sethoxydim, 5% calcium dodecylbenzene sulfonate + 8% polyoxyethylene sorbitan monooleate + 7% castor oil polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 6% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ quizalofop-p-ethyl (4+2)

A1+ quizalofop-p-ethyl + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 5% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 10% 100# solvent oil + methyl oleate

Dispersible oil suspending agent of A1+ oxyfluorfen (3+1)

A1+ oxyfluorfen + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 20% 100# solvent oil + methyl oleate

16, A1+ oxadiazon (3+1) dispersible oil suspending agent

A1+ oxadiazon + 5% calcium dodecylbenzene sulfonate + 8% cardanol polyoxyethylene ether + 6% castor oil polyoxyethylene ether + 2.5% organobentonite + 5% 100# solvent oil + methyl oleate

17, A1+ oxadiargyl (3+1) dispersible oil suspending agent

A1, oxadiargyl, 5 percent calcium dodecyl benzene sulfonate, 8 percent fatty alcohol-polyoxyethylene ether, 6 percent castor oil-polyoxyethylene ether, 2.5 percent organic bentonite, 2 percent fumed silica, 15 percent 100# solvent oil and methyl oleate

Aqueous suspension of A1+ atrazine (3+5)

A1+ atrazine + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.25% xanthan gum + 2.5% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

19, A1+ terbuthylazine (3+3) aqueous suspension

A1+ terbuthylazine + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.25% xanthan gum + 2.5% magnesium aluminium silicate + 0.1% defoamer + 3% ethylene glycol + water

Aqueous suspension of A1+ propanil (2+20)

A1+ propanil + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.16% xanthan gum + 1.6% magnesium aluminium silicate + 0.1% defoamer + 3% ethylene glycol + water

21, A1+ bentazone (4+30) aqueous suspension

A1+ bentazone + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.1% xanthan gum + 1.2% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

Dispersible oil suspending agent of A1+ butralin (4+21)

A1+ butralin + 10% decanamide + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 7% castor oil-polyoxyethylene ether + 1% organic bentonite + 1% fumed silica + 15% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ pendimethalin (4+21)

A1+ pendimethalin + 10% capramide + 6% calcium dodecylbenzenesulfonate + 8% fatty alcohol-polyoxyethylene ether + 5% castor oil-oxyethylene ether + 1% organobentonite + 1% fumed silica + 10% 100# solvent oil + methyl oleate

Dispersible oil suspending agent of A1+ butachlor (4+6)

A1+ butachlor + 6% calcium dodecylbenzene sulfonate + 6% fatty alcohol-polyoxyethylene ether + 8% cardanol-polyoxyethylene ether + 3% organobentonite + 3% fumed silica + methyl oleate

25, A1+ pretilachlor (2+4) dispersible oil suspending agent

A1+ pretilachlor + 5% calcium dodecylbenzene sulfonate + 6% fatty alcohol-polyoxyethylene ether + 8% cardanol-oxyethylene ether + 3% organobentonite + 3% fumed silica + methyl oleate

26, A1+ anilofos (4+2) dispersible oil suspension

A1+ anilofos + 5% calcium dodecylbenzenesulfonate + 8% cardanol polyoxyethylene ether + 7% castor oil oxyethylene ether + 3% organobentonite + 3% fumed silica + 12% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A1+ quinclorac (2+10)

A1+ quinclorac + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 2.0% organobentonite + 2.0% fumed silica + 10% 100# solvent oil + methyl oleate

A1+ fluroxypyr (2+3) dispersible oil suspension

A1+ fluroxypyr, 5% calcium dodecylbenzene sulfonate, 8% phenethylphenol polyoxyethylene ether, 6% castor oil oxyethylene ether, 3% organobentonite, 3% fumed silica, 10% 100# solvent oil and methyl oleate

29, A1+ Chlorofluoropyridine ester (3+1) dispersible oil suspension

A1+ fluroxypyridine ester + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-oxyethylene ether + 2.5% organobentonite + 2% fumed silica + methyl oleate

Dispersible oil suspension agent of A1+ 2-methyl-4-chlorophenoxyacetic acid (3+10)

A1+ 2-methyl-4-chlorophenoxyacetic acid + 6% calcium dodecylbenzene sulfonate + 8% cardanol polyoxyethylene ether + 6% castor oil oxyethylene ether + 2% organobentonite + 2.5% fumed silica + 12% 100# solvent oil + methyl oleate

Aqueous suspension of A1+ glyphosate (4+16)

A1+ glyphosate + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 3% propylene glycol block polyether + 0.2% salt tolerant xanthan gum + 2.0% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

32, A1+ glufosinate-ammonium (3+15) aqueous suspension

A1+ glufosinate-ammonium + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 3% propylene glycol block polyether + 0.2% salt tolerant xanthan gum + 2.0% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

Aqueous suspension of A1+ diquat (4+15)

A1+ diquat + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 3% propylene glycol block polyether + 0.2% salt tolerant xanthan gum + 2.0% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

34, A1+ cinmethylin (4+1) dispersible oil suspending agent

A1+ cycloheptane ether + 5% calcium dodecyl benzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 3% organic bentonite + 2% fumed silica + 12% 100# solvent oil + methyl oleate

35, A2+ mesotrione (4+1) dispersible oil suspension agent

A2+ mesotrione + 0.2% citric acid + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

36, A2+ topramezone (3+1) dispersible oil suspending agent

A2+ topramezone + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 7% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

37, A2+ topramezone (3+1) dispersible oil suspending agent

A2+ carfentrazone-ethyl, 0.2% citric acid, 5% calcium dodecyl benzene sulfonate, 9% fatty alcohol-polyoxyethylene ether, 6% castor oil-polyoxyethylene ether, 2.5% organobentonite, 2% fumed silica, 5% 100# solvent oil and methyl oleate

38, A2+ benzoxaflutole (4+4) dispersible oil suspending agent

A2+ benzoxaflutole + 0.2% citric acid + 5% calcium dodecylbenzenesulfonate + 9% cardanol polyoxyethylene ether + 6% castor oil polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

Dispersible oil suspension agent containing A2 and isoxaflutole (4+4)

A2+ isoxaflutole + 0.3% citric acid + 5% calcium dodecylbenzenesulfonate + 9% fatty alcohol-polyoxyethylene ether + 6% castor oil-oxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

A2+ clomazone (4+4) dispersible oil suspension

A2+ clomazone + 6% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 7% castor oil-polyoxyethylene ether + 2.5% organobentonite + 10% 100# solvent oil + methyl oleate

41, A2+ pyrazosulfuron (4+2) dispersible oil suspending agent

A2+ pyrazosulfuron-ethyl, 0.5% urea, 5% calcium dodecylbenzenesulfonate, 7% fatty alcohol-polyoxyethylene ether, 8% castor oil-polyoxyethylene ether, 2.5% organobentonite, 2% fumed silica, 5% 100# solvent oil and methyl oleate

42, A2+ penoxsulam (4+1) dispersible oil suspending agent

A2+ penoxsulam + 5% calcium dodecylbenzene sulfonate + 9% sorbitan monooleate polyoxyethylene ether + 5% castor oil oxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

43, A2+ imazamox (4+1) dispersible oil suspending agent

A2+ metopimox, 5% calcium dodecylbenzene sulfonate, 9% fatty alcohol-polyoxyethylene ether, 5% castor oil-polyoxyethylene ether, 2.5% organobentonite, 2% fumed silica, 5% 100# solvent oil and methyl oleate

Dispersible oil suspension agent containing A2+ mebendazole nicotinic acid (4+1)

A2+ mebendazole nicotinic acid + 5% calcium dodecylbenzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 5% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

45.A2+ bispyribac-sodium (4+1) dispersible oil suspending agent

A2+ Bispyribac-sodium, 5% calcium dodecylbenzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 5% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 5% 100# solvent oil + methyl oleate

46, A2+ clethodim (4+2) dispersible oil suspending agent

A2+ clethodim + 5% calcium dodecyl benzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 3% organobentonite + 2% fumed silica + 20% 100# solvent oil + methyl oleate

Dispersible oil suspension agent of A2+ sethoxydim (4+2)

A2+ sethoxydim, 5% calcium dodecylbenzene sulfonate + 9% fatty alcohol polyoxyethylene ether + 7% castor oil polyoxyethylene ether + 3% organobentonite + 2% fumed silica + 6% 100# solvent oil + methyl oleate

Dispersible oil suspending agent containing A2 and quizalofop-p-ethyl (4+2)

A2+ quizalofop-p-ethyl + 5% calcium dodecylbenzene sulfonate + 8% fatty alcohol-polyoxyethylene ether + 8% castor oil-polyoxyethylene ether + 2.5% organobentonite + 2% fumed silica + 6% 100# solvent oil + methyl oleate

49, A2+ oxyfluorfen (3+1) dispersible oil suspending agent

A2+ oxyfluorfen + 5% calcium dodecylbenzene sulfonate + 8% cardanol polyoxyethylene ether + 6% castor oil polyoxyethylene ether + 3% organobentonite + 2% fumed silica + 20% 100# solvent oil + methyl oleate

50, A2+ oxadiazon (3+1) dispersible oil suspension

A2, oxadiazon, 5 percent calcium dodecyl benzene sulfonate, 8 percent fatty alcohol-polyoxyethylene ether, 6 percent castor oil-polyoxyethylene ether, 3 percent organic bentonite, 5 percent 100# solvent oil and methyl oleate

51, A2+ oxadiargyl (3+1) dispersible oil suspending agent

A2, oxadiargyl, 5 percent calcium dodecyl benzene sulfonate, 8 percent fatty alcohol-polyoxyethylene ether, 6 percent castor oil-polyoxyethylene ether, 2.5 percent organic bentonite, 2 percent fumed silica, 15 percent 100# solvent oil and methyl oleate

52, A2+ atrazine (3+5) aqueous suspension

A2+ atrazine + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.22% xanthan gum + 2.2% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

53.A2+ terbuthylazine (3+3) water suspension agent

A2+ terbuthylazine + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.26% xanthan gum + 2.2% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

A2+ propanil (2+20) aqueous suspension

A2+ propanil + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.18% xanthan gum + 1.8% magnesium aluminium silicate + 0.1% defoamer + 3% ethylene glycol + water

55, A2+ bentazone (4+30) aqueous suspension

A2+ bentazone + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 0.12% xanthan gum + 1.5% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

56.A2+ butralin (4+21) dispersible oil suspending agent

A2+ butralin + 10% decanamide + 5% calcium dodecylbenzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 7% castor oil-polyoxyethylene ether + 1% organic bentonite + 1% fumed silica + 10% 100# solvent oil + methyl oleate

57, A2+ pendimethalin (4+21) dispersible oil suspending agent

A2+ pendimethalin + 10% capramide + 6% calcium dodecylbenzenesulfonate + 9% fatty alcohol-polyoxyethylene ether + 5% castor oil-oxyethylene ether + 1% organobentonite + 1% fumed silica + 10% 100# solvent oil + methyl oleate

58.A2+ butachlor (4+6) dispersible oil suspending agent

A2+ butachlor + 6% calcium dodecylbenzene sulfonate + 9% cardanol polyoxyethylene ether + 7% castor oil polyoxyethylene ether + 3% organobentonite + 2% fumed silica + methyl oleate

59, A2+ pretilachlor (2+4) dispersible oil suspending agent

A2+ pretilachlor + 5% calcium dodecylbenzene sulfonate + 9% anacardol polyoxyethylene ether + 7% castor oil polyoxyethylene ether + 3% organobentonite + 2% fumed silica + methyl oleate

Dispersible oil suspension agent of A2+ anilofos (4+2)

A2+ anilofos + 5% calcium dodecylbenzenesulfonate + 9% fatty alcohol-polyoxyethylene ether + 7% castor oil-polyoxyethylene ether + 3% organobentonite + 2% fumed silica + 12% 100# solvent oil + methyl oleate

61.A2+ quinclorac (2+10) dispersible oil suspending agent

A2+ quinclorac + 5% calcium dodecylbenzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 2.5% organobentonite + 10% 100# solvent oil + methyl oleate

62, A2+ fluroxypyr (2+3) dispersible oil suspension

A2+ fluroxypyr, 5% calcium dodecylbenzene sulfonate, 9% phenethylphenol polyoxyethylene ether, 6% castor oil oxyethylene ether, 3% organobentonite, 3% fumed silica, 10% 100# solvent oil and methyl oleate

63.A2+ cyhalopyridine ester (3+1) dispersible oil suspending agent

A2+ fluroxypyridine ester + 5% calcium dodecylbenzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 6% castor oil-oxyethylene ether + 3% organobentonite + 2% fumed silica + 12% 100# solvent oil + methyl oleate

64, A2+ 2-methyl-4-chlorophenoxyacetic acid (3+10) dispersible oil suspending agent

A2+ 2-methyl-4-chlorophenoxyacetic acid + 6% calcium dodecylbenzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 6% castor oil-oxyethylene ether + 2% organobentonite + 1% fumed silica + 12% 100# solvent oil + methyl oleate

65.A2+ glyphosate (4+16) aqueous suspension

A2+ glyphosate + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 3% propylene glycol block polyether + 0.2% salt tolerant xanthan gum + 1% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

66.A2+ glufosinate (3+15) aqueous suspension

A2+ glufosinate-ammonium + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 3% propylene glycol block polyether + 0.2% salt tolerant xanthan gum + 1% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

A2+ diquat (4+15) aqueous suspension

A2+ diquat + 5% polycarboxylate + 2% phenethylphenol polyoxyethylene ether phosphate triethanolamine salt + 3% propylene glycol block polyether + 0.2% salt tolerant xanthan gum + 1% magnesium aluminum silicate + 0.1% defoamer + 3% ethylene glycol + water

68.A2+ cinmethylin (4+1) dispersible oil suspending agent

A2+ cycloheptane ether + 5% calcium dodecyl benzene sulfonate + 9% fatty alcohol-polyoxyethylene ether + 6% castor oil-polyoxyethylene ether + 3% organic bentonite + 2% fumed silica + 10% 100# solvent oil + methyl oleate

The processing equipment of the aqueous suspending agent comprises: mixing kettles, colloid mills, sand mills, shearing machines and the like.

The processing process of the aqueous suspending agent comprises the following steps: putting all materials into a mixing kettle, stirring and mixing, passing through a colloid mill, then entering a sand mill for three-stage sand milling, finally uniformly shearing in a shearing machine, and transferring to a storage tank for filling after the test is qualified.

The processing equipment of the dispersible oil suspending agent comprises the following steps: mixing kettles, colloid mills, sand mills, shearing machines and the like.

The processing process of the dispersible oil suspending agent comprises the following steps: putting all materials into a mixing kettle, stirring and mixing, passing through a colloid mill, then entering a sand mill for three-stage sand milling, finally uniformly shearing in a shearing machine, and transferring to a storage tank for filling after the test is qualified.

B) Test of drug efficacy

Spraying treatment of stems and leaves after seedling:

1) test conditions

1.1) test target

The shaped Cyperus is obtained from Hubei Jingzhou, the shredded Cyperus is obtained from Jiangxi Shang, the monochoria vaginalis is obtained from Hunan Changsha, the rice barnyard grass is obtained from Heilongjiang chang, the edible tulip is obtained from Liaoning Yingkou, the Chinese iris is obtained from Heilongjiang tiger forest, the ludwigia prostrata is obtained from Hunan Changsha, the digitaria is obtained from Anglo-hui, and the oriental waterplantain rhizome is obtained from Liaoning Shenyang. The weeds are cultured by a pot culture method, plastic nutrition bowls with the size of 180 х 140mm are placed in an enamel tray, surface soil (4/5) which is collected from a farmland and is dried and sieved is filled in the enamel tray, the soil humidity is controlled to be 20% at the initial stage, weed seeds with full and uniform seeds are selected, the weed seeds are soaked in warm water with the temperature of 25 ℃ for 6 hours, germination is accelerated in a biochemical incubator (dark) with the temperature of 28 ℃, the weed seeds which are just exposed to the white are uniformly placed on the surface of the soil, and then the enamel tray is covered with 0.5-1cm of soil according to the particle size of the seeds.

1.2) culture conditions

The method is carried out in a controllable sunlight greenhouse, the temperature is 20-30 ℃, the natural illumination is carried out, and the relative humidity is 57-72%. The soil type is loam, the organic matter content is 1.63%, the pH value is 7.1, the alkaline hydrolysis nitrogen is 84.3mg/kg, the quick-acting phosphorus is 38.5mg/kg, and the quick-acting potassium is 82.1 mg/kg.

1.3), instrumentation

3WP-2000 model walking spray tower, Minn Jing agricultural machinery research institute of agricultural department. Ten thousandth electronic balance type GA10 (germany); ZDR2000 intelligent data recorder (hangzhou ze large instruments ltd); SPX type intelligent biochemical incubator (Ningbo Jiangnan Instrument factory).

2) Design of experiments

2.1), reagents

The desired active ingredient a comes from patent CN201911014193.5, and its specific preparation process is as follows:

(1) synthesis of compound a 1:

(1.1) sequentially adding Cpd 1(3g,16mmol,1.0eq) and NaOH (0.72g,18mmol,1.1eq) to 30ml of DMF and then adding Cpd 2(1.28g,16.8mmol,1.05eq) dropwise at 0 ℃ followed by stirring the reaction at 0 ℃ for 1 hour. LCMS detection showed the starting material was essentially reacted to completion with a major new peak. The reaction was poured into 30ml of water, the layers separated, the aqueous phase extracted once with 50ml of ethyl acetate and the organic phase washed three times with saturated brine (50ml), dried, spin dried and isolated by column chromatography to give Cpd 3(3.6g, 91% yield) (colourless oil).

(1.2) Cpd 3(3.1g,13mmol,1.0eq) was added to 30ml of THF followed by slow addition of n-BuLi (6.42ml,2.5M,16mmol,1.2eq) at-78 deg.C and stirring of the reaction mixture at-78 deg.C for 0.5 h followed by slow CO addition₂After 10min, the reaction solution was slowly warmed to room temperature. LCMS detected product. To the reaction mixture was poured 20ml of water, the layers were separated, the aqueous phase was extracted once with 30ml of ethyl acetate, the aqueous phase was gradually adjusted to pH 4-5 with concentrated hydrochloric acid, filtered and dried to give Cpd 4(3.2g, 87% yield) (white solid).

(1.3) to 30ml of pyridine were added sequentially Cpd 4(3.1g,11mmol,1.0eq), Cpd 5(1.66g,16.8mmol,1.5eq) and DMAP (0.13g,1.1mmol,0.1 eq). Then slowly adding SOCl at the temperature of 0 DEG C₂(2.0g,16.8mmol,1.5eq), and the reaction was stirred at room temperature for 3 hours. LCMS detected product. After removal of pyridine by concentration, 30ml of water was poured into the reaction mixture, the mixture was separated, the aqueous phase was extracted three times with 30ml of ethyl acetate, the organic phase was washed three times with saturated brine (50ml), dried, spin-dried, and isolated by column chromatography to give compound Cpd 6(2.5g, 63% yield) (white solid).

(1.4) to 10ml of dichloromethane were added sequentially Cpd 6(1g,2.8mmol,1.0eq) and m-CPBA (0.54g,3.1mmol,1.1 eq). The reaction was then stirred at room temperature for 1 hour. The LCMS detects the product and the raw materials are basically reacted completely. The reaction was poured into 10ml of water, quenched with sodium bisulfite, separated, the aqueous phase extracted three times with 30ml of dichloromethane, the organic phase washed once with saturated brine (30ml), dried, spun-dried and isolated by column chromatography to give compound a1(0.85g, 82% yield) (off-white solid).

¹H NMR(500MHz,DMSO-d₆)12.57(s,1H),8.07(dd,J＝8.0,7.0Hz,1H),7.82(d,J＝8.0Hz,1H),3.57-3.47(m,2H),2.48(s,3H),1.70-1.52(m,2H),1.08-0.93(m,3H).

(2) Synthesis of compound a 2:

compound A1(0.5g, 98% purity) was resolved by chiral HPLC (Column: CHIRALPAK IG; Column Size: 3 cm. times.25 cm,5 um; Injection: 3.0 ml; Mobile phase: Hex (0.2% FA): IPA 50: 50; Flow rate: 28 ml/min; Wavelength: UV 254 nm; Temperature:25 ℃; Sample solution: 70mg/ml in EtOH/DCM; Run time 60mins) and concentrated after single crystal diffraction to give A2(R configuration) (0.16g, Rt 10.51min, 100% purity ee, 98%).

The active ingredients B required are diconazole, bicyclopyrone, topramezone, triazophone,For the company, others were purchased by the reagent company. The raw medicines are all diluted by using an emulsifier Tween-80 aqueous solution with the content of 0.1 percent and taking acetone as a solvent.

Wherein the content of the first and second substances,from patent CN201911321469.4, the preparation method is as follows:

1) compound a (0.5g, 2.13mmol), compound b (313mg, 2.55mmol), a catalytic amount of TBAB (10mg), DMF (10mL) was placed in a round bottom flask and stirred at room temperature 15 ℃ for 24 h. And (5) detecting a small amount of residual raw materials by liquid quality, and then treating. The reaction was poured into 50mL of water, extracted 2 times with methyl tert-butyl ether (50mL × 2), the organic phase was dried, concentrated, and purified by column chromatography to give compound c (300mg, yield 50%). Compound c is a white solid.

(2) Compound c (0.3g, 1.06mmol) and methanol (20mL) were placed in a 100mL single-neck flask, and lithium hydroxide (44.5mg, 1.06mmol) was dissolved in 2mL of water, and slowly added dropwise to the single-neck flask at room temperature, followed by stirring at room temperature for 12 hours. After the reaction of the raw materials is finished, adjusting the pH to 5-6 with 0.5M dilute hydrochloric acid, concentrating, and extracting with water and ethyl acetate. The organic phase was dried and concentrated to give compound d (200mg, yield 70%) as a white solid.

(3) Compound d (200mg, 0.74mmol), compound e (75mg, 0.74mmol), DCC (152mg, 0.74mmol), and anhydrous DCM (20mL) were placed in a 100mL round-bottomed flask and reacted at room temperature for 12 hours. After the reaction of the starting materials was completed, the reaction solution was concentrated and separated by column chromatography to give the objective compound (200mg, yield 77%) as a white solid.

¹H NMR(500MHz,Chloroform-d)δ5.28(q,J＝7.0Hz,1H),5.15(s,2H),4.27–4.07(m,3H),3.91–3.73(m,2H),2.04–1.82(m,3H),1.66(d,J＝7.0Hz,3H),1.59-1.54(m,1H).

2.2) test treatment

2.2.1), dose setting

When determining the ratio or content of the component A and the component B, the main use purpose of the formula is also considered according to the action characteristics of the two medicaments and the measurement of toxicity and the like. On the basis of preliminary experiments, A, B active ingredients are respectively used singly and mixed in different amounts. Water without drug, containing the same solvent and emulsifier was used as a blank.

2.2.2), test repetition

Each treatment was repeated 4 times, 3 pots each time, and 20 weed seeds were sown per pot for 60 plants each time.

2.3) treatment method

2.3.1), treatment time and number of times

The test was performed 1 time in total. And (3) thinning after 1-1.5 leaf period of weeds, keeping 15 weeds in each pot, keeping 45 weeds in each treatment, and then continuously culturing until 2-3 leaves are treated.

2.3.2), instruments and methods of use

Uniformly placing the cultured test material on a 0.5m area²Spraying stem and leaf by using a 3WP-2000 model walking spray tower on the platform, wherein the liquid spraying amount is 450 kg/hectare, and the spraying pressure is 0.3 MPa. And after all the liquid medicine is sprayed, closing the air valve, opening the spraying tower door after 30 seconds, and taking out the nutrition pot. Then the air valve is opened, 50mL of clean water is sprayed, and the liquid spraying pipe is cleaned.

3) Test method

The potting method is adopted. The weed cultivation is shown in 1.1), and the method is carried out according to 'herbicide in pesticide indoor bioassay test guidelines'. The application method is shown in 2.3.2), and stem and leaf treatment method is adopted. After treatment, the cells were transferred to a greenhouse for conventional culture.

4) Data investigation and statistical analysis

4.1) investigation method

The complete survival weed seedlings are cut off along the soil surface by a blade by adopting an absolute number survey method, and the fresh weight of the weeds is weighed by an analytical balance. For the weeds that have died, the fresh weight is zero.

4.2), investigation time and number of surveys

The investigation was carried out 15 days after the treatment, and was carried out 1 time in total.

4.3), statistical analysis of data

The theoretical fresh weight inhibition rate (E0 ═ X + Y-X Y/100) of each treatment mixed combination is calculated by a Gowing method, and then compared with the actually measured inhibition rate (E), the combined action type of the two mixed combinations on the weeds is evaluated, and when the E-E0 value is more than 10 percent, the effect is synergistic, when the E-E0 value is less than-10 percent, the effect is antagonistic, and when the E-E0 value is between-10 percent and 10 percent, the effect is additive. And the optimal proportion is determined according to factors such as actual control effect, characteristics of the herbicide, balance of the formula and the like. Wherein X is the fresh weight inhibition rate when the dosage of the active component A is P; y is the fresh weight inhibition rate of the active component B when the dosage is Q. The statistical results are shown in tables 1-223 below.

Table 1A 1 evaluation of the actual control and combination of mesotrione mixed to cyperus rotundus

Table 2A 1 evaluation of the actual control and combination of topramezone on sedge heterotypii

Table 3A 1 evaluation of the actual control and combination of the Cyclofonone mixtures on the action of Cyperus rotundus

Table 4A 1 evaluation of the actual control and combination of fluroxypyr and Cyperus rotundus

TABLE 5A 1 evaluation of the actual control and combination of Fusulcotrione on Cyperus rotundus

TABLE 6A 1 evaluation of the actual control and combination of the Doxodim with the mixture of Cyperus rotundus for Cyperus rotundus

Table 7A 1 evaluation of the actual control and combination of topramezone on sedge heterotypii

TABLE 8A 1 evaluation of the actual control and Combined Effect of Cyclopyraflutole on Cyperus rotundus

TABLE 9A 1 evaluation of the actual control and combination of mesotrione mixed with cyperus rotundus

TABLE 10A 1 evaluation of the actual control and combination of isoxaflutole with the blended benzoxaflutole on cyperus rotundus

TABLE 11A 1 evaluation of the actual control and combination of isoxaflutole on sedge heterotypic

TABLE 12A 1 evaluation of the actual control and combination of diflufenican on sedge heterotypii with the compounding of diflufenican

TABLE 13A 1 evaluation of the actual control and combination of diflufenican on sedge heterotypii with compounding of diflufenican

TABLE 14A 1 evaluation of the actual control and combination of clomazone on cyperus alternifolius

TABLE 15A 1 evaluation of actual control and combination of thifensulfuron methyl on monochoria vaginalis

TABLE 16A 1 evaluation of the actual control and joint action of the mixed bensulfuron methyl on the monochoria vaginalis

TABLE 17A 1 evaluation of the actual control and joint action of pyrazosulfuron-ethyl on monochoria vaginalis

TABLE 18A 1 evaluation of the actual control and combination of thidiazuron on monochoria vaginalis

TABLE 19A 1 evaluation of the actual control and joint action of halosulfuron-methyl on monochoria vaginalis

TABLE 20A 1 evaluation of the actual control and combination of rimsulfuron on Ottelia communis

TABLE 21A 1 evaluation of the actual control and combination of Flucarbazone-sodium for herba Monochoriae

TABLE 22A 1 evaluation of actual control and combination of Mesosulfuron-methyl on monochoria vaginalis

TABLE 23A 1 evaluation of actual control and joint action of nicosulfuron on monochoria vaginalis

TABLE 24A 1 evaluation of the actual control and combination of the foramsulfuron against monochoria vaginalis

TABLE 25A 1 evaluation of the actual control and combined action of flumetsulam on monochoria vaginalis

TABLE 26A 1 evaluation of the actual control and combination of the Fluoroketofonamide on monochoria vaginalis

TABLE 27A 1 evaluation of the actual control and combined action of penoxsulam on monochoria vaginalis

TABLE 28A 1 evaluation of the actual control and combination of the Oncorhynchus vaginalis by the Mixed cloransulam-methyl

TABLE 29A 1 evaluation of the actual control and combination of pyribenzoxim on monochoria vaginalis

TABLE 30A 1 evaluation of actual control and combination of imazamox blended with monochoria herb on monochoria vaginalis

TABLE 31A 1 evaluation of the actual control and combination of imazapic with the compounding of imazapic

TABLE 32A 1 evaluation of actual control and combination of the sodium iodosulfuron for monochoria vaginalis

TABLE 33A 1 evaluation of actual control and combination of Bispyribac-sodium by compounding Bispyribac-sodium

TABLE 34A 1 evaluation of the actual control and combination of pinoxaden with the compound pinoxaden

TABLE 35A 1 evaluation of the actual control and Combined action of the compounded clethodim on rice Echinochloa crusgalli

TABLE 36A 1 evaluation of the actual control and Combined action of mixed sethoxydim on Echinochloa crusgalli

TABLE 37A 1 evaluation of the actual control and combined action of quizalofop-p-ethyl on rice barnyard grass

TABLE 38A 1 evaluation of the actual control and combined action of haloxyfop-R-methyl compounded with haloxyfop-R-methyl on rice barnyard grass

TABLE 39A 1 evaluation of the actual control and combination of topramezone on rice barnyard grass

TABLE 40A 1 evaluation of the actual control and combination of metamifop for rice barnyard grass

TABLE 41A 1 evaluation of the actual control and combination of oxyfluorfen in Cyperus rotundus

TABLE 42A 1 evaluation of the actual control and combination of fomesafen to cyperus alternifolius

TABLE 43A 1 evaluation of the actual control and combination of oxadiazon on cyperus rotundus

TABLE 44A 1 evaluation of the actual control and combination of oxadiargyl on cyperus alternifolius

TABLE 45A 1 evaluation of the actual control and combination of sulfentrazone on cyperus rotundus

TABLE 46A 1 evaluation of the actual control and combination of pyraclonil with cypermethrin for cyperus rotundus

TABLE 47A 1 evaluation of the actual control and combination of flumioxazin on cyperus heterotropoides

TABLE 48A 1 evaluation of the actual control and combination of the effect of the clomazone on sedges of allotype

TABLE 49 evaluation of the actual control and combination of tiafenacil mixed with nutgrass flatsedge

Table 50A 1 evaluation of actual control effect and combined effect of mixed saflufenacil on profiled cyperus rotundus

TABLE 51A 1 evaluation of the actual control and Combined action of Mixed carfentrazone-ethyl on sedge heterotypii

TABLE 52A 1 evaluation of the actual control and combination of acifluorfen-ethyl to sedge heterotypium

TABLE 53 evaluation of actual control and Combined action of acifluorfen mixed with 1 on cyperus alternifolius

TABLE 54A 1 evaluation of the actual control and combination of triflumimoxazin against Cyperus rotundus

TABLE 55A 1 evaluation of the actual control and combination of atrazine mixed with cyperus alternifolius

TABLE 56A 1 evaluation of the actual control and combination of terbuthylazine in the formulation of Cyperus rotundus

TABLE 57A 1 evaluation of the actual control and Combined action of the Mixed ametryn against sedges heterotypic

TABLE 58A 1 evaluation of the actual control and Combined action of Mixed metribuzin on sedges of allotype

TABLE 59A 1 evaluation of the actual control and Combined action of amicarbazone on Cyperus rotundus

TABLE 60 evaluation of the actual control and combination of Chloroluron mixed with Cyperus rotundus for cyperus esculentus

TABLE 61A 1 evaluation of the actual control and combination of isoproturon compounded on Cyperus rotundus

TABLE 62 evaluation of the actual control and Combined action of the herbicidal composition of A1 on cyperus rotundus

TABLE 63A 1 evaluation of the actual control and Combined action of trifluoxazine on cyperus alternifolius

TABLE 64A 1 evaluation of the actual control and combination of cycloprominate mixtures on cyperus alternifolius

TABLE 65A 1 evaluation of the actual control and combination of propanil with cyperus rotundus

TABLE 66A 1 evaluation of the actual control and combination of pyridate on cyperus alternifolius

TABLE 67A 1 evaluation of the actual control and combination of bentazon blends on sedges of abnormal shape

TABLE 68A 1 evaluation of the actual control and combination of bromoxynil compounds on cyperus alternifolius

TABLE 69 evaluation of the actual control and combination of butralin blended with Cyperus rotundus in Table 69A 1

TABLE 70A 1 evaluation of the actual control and combination of pendimethalin blended with cyperus rotundus

TABLE 71A 1 evaluation of the actual control and combination of butachlor in mixed form for cyperus alternifolius

TABLE 72 evaluation of the actual control and combination of pretilachlor mixed with Cyperus rotundus in Table 72A 1

TABLE 73A 1 evaluation of the actual control and combination of S-metolachlor on cyperus alternifolius

TABLE 74A 1 evaluation of the actual control and combination of flufenacet in combination with Cyperus rotundus

TABLE 75A 1 evaluation of the actual control and Combined action of Mixed Sulfoxaden on sedges

TABLE 76A 1 evaluation of the actual control and combination of anilofos when blending with anilofos for cyperus rotundus

TABLE 77A 1 evaluation of the actual control and combination of prosulfocarb on Chufa

TABLE 78A 1 evaluation of the actual control and Combined action of the blended crop of Bisodafop masam

TABLE 79 evaluation of the actual control and Combined action of the Mixed Liaodan to the Cyperus rotundus of Table 79A 1

TABLE 80A 1 evaluation of the actual control and combination of quinclorac on edible tulip

TABLE 81A 1 evaluation of the actual control and Combined Effect of fluroxypyr-compounded on Pseudobulbus Cremastrae seu pleiones

TABLE 82A 1 evaluation of the actual control and combination of halopyridyl fluoroate on Pseudobulbus Cremastrae seu pleiones

TABLE 83A 1 evaluation of the actual control and combination of triclopyr on Pseudobulbus Cremastrae seu pleiones

TABLE 84A 1 evaluation of the actual control and combination of clopyralid on edible tulip

TABLE 85A 1 evaluation of the actual prevention and combination of Picloram against Pseudobulbus Cremastrae seu pleiones

TABLE 86A 1 evaluation of the actual control and combination of aminopyralid on Pseudobulbus Cremastrae seu pleiones

TABLE 87A 1 evaluation of the actual efficacy and combined action of dicamba compounded on edible tulip

TABLE 88A 1 evaluation of the actual control and combination of fluroxypyr meptyl on Pseudobulbus Cremastrae seu pleiones

TABLE 89A 1 evaluation of the actual controlling effect and combined action of 2-methyl-4-chlorophenoxyacetic acid compounded on edible tulip

TABLE 90A 1 evaluation of the actual control and combination of aminocyclopyrachlor in Pseudobulbus Cremastrae seu pleiones

TABLE 91A 1 evaluation of actual control and Combined action of Glyphosate mixture on Ottelia communis

TABLE 92A 1 evaluation of actual control and Combined action of the mixed glufosinate-ammonium on monochoria vaginalis

TABLE 93A 1 evaluation of actual control and Combined action of the Mixed glufosinate-ammonium on monochoria vaginalis

TABLE 94 evaluation of actual control and joint action of diquat mixed with diquat on monochoria vaginalis

TABLE 95A 1 evaluation of the actual control and combined action of triazineone flumioxazin on monochoria vaginalis

TABLE 96A 1 evaluation of the actual control and combination of the hybrid indoxazine-flumetsulam on monochoria vaginalis

TABLE 97A 1 evaluation of the actual control and combination of oxaziclomefone on monochoria vaginalis

TABLE 98A 1 evaluation of the actual control and combination of the Rohdea japonica with the mixed cinmethylin

TABLE 99A 2 evaluation of the actual control and combination of mesotrione mixed to Fluoritum

TABLE 100A 2 evaluation of the actual control and combined action of topramezone on Fluoritum

TABLE 101A 2 evaluation of the actual prevention and combination of Fluoritum by blending with Ring Sulfonone

TABLE 102A 2 evaluation of the actual control and combined action of Fluoritone on Fluoritum

TABLE 103A 2 evaluation of the actual control and combination of Fusulone on Fluoritum

TABLE 104A 2 evaluation of the actual control and combination of Fluoritone on Fluoritum by blending with benzobicylon

TABLE 105A 2 evaluation of the actual control and combined action of mixedly diazolone on Fluoritum

TABLE 106A 2 evaluation of the actual control and combined action of Fluoritone on Fluoritum by blending Cyclopyraflutole

TABLE 107A 2 evaluation of the actual control and combination of Fluoritum with mixed triazasulam

Table 108A 2 evaluation of actual control effect and combined effect of blended benzoxaflutole on firefly iris

TABLE 109A 2 evaluation of the actual control and combination of isoxaflutole on Fluoritum

TABLE 110A 2 evaluation of the actual control and joint action of Fluoritan on Fluoritan

TABLE 111A 2 evaluation of the actual control and combination of Fluorum by compounding Fluopyram

TABLE 112A 2 evaluation of the actual control and combination of Dioscorea Opposita Linne by mixing with clomazone

TABLE 113A 2 evaluation of actual control and combination of thifensulfuron methyl

TABLE 114A 2 evaluation of actual control and combination of bensulfuron methyl for ludwigia prostrata

TABLE 115A 2 evaluation of actual control and combination of pyrazosulfuron-ethyl for ludwigia prostrata

TABLE 116A 2 evaluation of actual control and combination of thifensulfuron methyl on ludwigia prostrata

TABLE 117A 2 evaluation of actual control and combination of halosulfuron-methyl on ludwigia prostrata

TABLE 118A 2 evaluation of actual control and combination of rimsulfuron with ludwigia prostrata

TABLE 119A 2 evaluation of actual control effect and combined action of Flucarbazone-sodium on ludwigia prostrata

TABLE 120A 2 evaluation of actual prevention and combination of Disulfuron methyl for cloves and Polygonum hydropiper

TABLE 121A 2 evaluation of actual control effect and joint action of nicosulfuron on ludwigia prostrata

TABLE 122A 2 evaluation of actual control and combination of coumarone for ludwigia prostrata

TABLE 123A 2 evaluation of the actual control and combined action of flumetsulam on ludwigia prostrata

TABLE 124A 2 evaluation of actual control and combination of Symphytum officinale by compounding triafamone

TABLE 125A 2 evaluation of actual control and combined action of penoxsulam on ludwigia prostrata

TABLE 126A 2 evaluation of actual prevention and combination of cloransulam-methyl for ludwigia prostrata

TABLE 127A 2 evaluation of the actual control and combination of Liquidambaris syringae with Pyrithiobac sodium

TABLE 128A 2 evaluation of actual prevention and combination of imazamox blended with ludwigia prostrata

TABLE 129A 2 evaluation of actual control and combination of Dioscorea bulbifera with Memidazolinin

TABLE 130A 2 evaluation of actual control and combination of Lonicera caryophyllata with iodosulfuron-methyl sodium

TABLE 131A 2 evaluation of actual prevention and combination of Bispyribac-sodium for Diospyros hydropiper

TABLE 132A 2 evaluation of the actual control and Combined Effect of pinoxaden blended with Datang

TABLE 133A 2 evaluation of the actual control and Combined Effect of the Compound clethodim on crabgrass

TABLE 134A 2 evaluation of the actual control and Combined Effect of Mixed sethoxydim on crab and Tang

TABLE 135A 2 evaluation of the actual control and Combined action of quizalofop-p-ethyl on large crabgrass

TABLE 136A 2 evaluation of the actual control and joint action of haloxyfop-R-methyl on large crabgrass

TABLE 137A 2 evaluation of the actual control and combination of cycloxydim on large crabgrass

TABLE 138 evaluation of actual prevention and combination of metamifop mixed with 2 for crab

TABLE 139A 2 evaluation of the actual control and joint action of Fluoritan on Fluoritan

TABLE 140A 2 evaluation of the actual control and combination of Fluoritan to Fluoritan

TABLE 141A 2 evaluation of the actual control and combination of the effect of compounding oxadiazon on firefly iris

TABLE 142A 2 evaluation of the actual control and combination of oxadiargyl on Fluoritum

TABLE 143A 2 evaluation of the actual control and combined action of mixed sulfentrazone on Fluoritum

TABLE 144A 2 evaluation of the actual control and combination of pyraclonil with respect to Fluoritum

TABLE 145A 2 evaluation of the actual control and combination of flumioxazin on Fluoritum

TABLE 146A 2 evaluation of the actual control and combination of Fluoritum by blending pentoxazone

TABLE 147A 2 evaluation of the actual control and combination of the Fluoritum by blending tiafenacil

TABLE 148A 2 evaluation of the actual control and joint action of saflufenacil on Fluorita was

TABLE 149A 2 evaluation of the actual control and combined action of Mixed Toxolone on Fluorita

TABLE 150A 2 evaluation of actual prevention and combination of Fluoritum with Fluoritum

TABLE 151A 2 evaluation of the actual control and combination of Fluoritum with mixed acifluorfen

Evaluation of actual control and combined action of triflumimoxazin mixed with table 152A 2 on firefly iris

TABLE 153A 2 evaluation of the actual prevention and combination of the Oxydazine mixture on Iris lactuca

TABLE 154A 2 evaluation of actual control and joint action of Fluoritum by blending terbuthylazine

TABLE 155A 2 evaluation of the actual control and combination of ametryn against Flutter

TABLE 156A 2 evaluation of the actual control and combined action of metribuzin on Fluoritum

TABLE 157A 2 evaluation of the actual control and combination of amicarbazone on Fluoritum

TABLE 158A 2 evaluation of the actual control and combination of Luceruron on Fluoritum

TABLE 159A 2 evaluation of the actual control and combination of isoproturon on Flutter

TABLE 160A 2 evaluation of actual control and joint action of herbicide mixture on Fluorita pallida

TABLE 161A 2 evaluation of the actual control and combination of trifluoxazine on Fluoritum

TABLE 162A 2 evaluation of the actual control and combination of action of cyclopyromate on Fluoritum

Table 163A 2 evaluation of actual control and combination of Diphenna with propanil

TABLE 164A 2 evaluation of the actual control and combination of pyridate on Fluoritan

TABLE 165A 2 evaluation of the actual control and joint action of bentazon on Fluoritum

TABLE 166A 2 evaluation of the actual control and combination of bromoxynil compounds on Fluoritum

TABLE 167A 2 evaluation of the actual control and joint action of butralin mixed on Fluoritum

TABLE 168A 2 evaluation of the actual control and joint action of pendimethalin mixed on Fluoritum

TABLE 169A 2 evaluation of the actual control and combined action of butachlor mixed with Fluoritan on Fluorita

TABLE 170A 2 evaluation of the actual control and combination of pretilachlor on Fluoritum

TABLE 171A 2 evaluation of the actual control and combination of S.ophrax by the mixed s.metolachlor

TABLE 172A 2 evaluation of the actual control and combined action of flufenacet mixed with Fluticacet on Fluoritum

TABLE 173A 2 evaluation of the actual control and combination of Sulfuron pyraflufen-ethyl on Fluoritum

TABLE 174A 2 evaluation of the actual control and combination of Shabarbus-grass phosphorus on Fluorita

TABLE 175A 2 evaluation of the actual control and combination of the blended prosulfocarb on Flutter

TABLE 176A 2 evaluation of the actual control and combination of the Eben-Dip-Fluoritum

TABLE 177A 2 evaluation of the actual control and joint action of mixed pellet on Fluorita (L.) Linnaeus

TABLE 178A 2 evaluation of the actual prevention and combination of Quinclorac on Alisma orientale

TABLE 179A 2 evaluation of actual control and Combined Effect of fluroxypyr on Alisma orientale compounded

TABLE 180A 2 evaluation of actual prevention and combination of Fluoropicolide against Alismatis rhizoma

TABLE 181A 2 evaluation of the actual prevention and combination of triclopyr on Alismatis rhizoma

TABLE 182A 2 evaluation of the actual prevention and combination of clopyralid to Alisma orientale

TABLE 183A 2 evaluation of actual prevention and combination of Aminopyric acid to Alismatis rhizoma

TABLE 184A 2 evaluation of actual prevention and combination of Lophathernalin for Alismatis rhizoma

TABLE 185A 2 evaluation of the actual prevention and combination of Dicamba compounded with Alisma orientale

TABLE 186A 2 evaluation of actual control and combination of CfCPDO to Alismatis rhizoma

TABLE 187A 2 evaluation of actual prevention and combination of Alismatis rhizoma with 2-methyl-4-chlorophenoxyacetic acid

TABLE 188A 2 evaluation of the actual prevention and combination of Cytosporanic acid on Alisma orientale

TABLE 189A 2 evaluation of actual control and combination of Glyphosate blends on ludwigia prostrata

TABLE 190A 2 evaluation of actual control and combination of glufosinate-ammonium for ludwigia prostrata

Evaluation of actual prevention effect and combined effect of table 191A 2 mixed with glufosinate-ammonium on ludwigia prostrata

TABLE 192A 2 evaluation of actual control and combination of Dimox to ludwigia prostrata

TABLE 193A 2 evaluation of the actual control and combination of triazineammoniol on ludwigia prostrata

TABLE 194 evaluation of the actual control and combination of indoxazin-flutolanil to ludwigia prostrata by compounding 194A 2

Evaluation of actual control effect and combined effect of mixed oxaziclomefone in table 195A 2 on ludwigia prostrata

TABLE 196A 2 evaluation of actual control and Combined action of Polygala crotalarioides on Ludwigia prostrata

TABLE 197A 1 evaluation of the actual control and Combined Effect of sodium salt compounded with Triazolesulfonylvanine on Cyperus rotundus

TABLE 198A 1 evaluation of the actual control and combination of halopyridyl chlorofluoride with sodium salt to Pseudobulbus Cremastrae seu pleiones

TABLE 199A 2 evaluation of the actual control and combination of propanil with Fluoritum

TABLE 200A 2 evaluation of the actual control and combination of Shabarnyard grass phosphorus mixed with potassium salt on Fluoritum

TABLE 201 evaluation of actual prevention and combination of potassium salt 2 with 2-methyl-4-chlorophenoxyacetic acid to Alismatis rhizoma

TABLE 202A 2 evaluation of actual control and combination of Fenquinotrione on Alismatis rhizoma

TABLE 203A 2 evaluation of the actual prevention and combination of beflubutamid to Alisma orientale

TABLE 204A 2 evaluation of the actual prevention and combination of Fluazinone to Alismatis rhizoma

TABLE 205A 2 evaluation of actual control and combination of fluorescent lights with Bixlozone

TABLE 206A 2 evaluation of the actual control effect and combined action of mixed oxazine pyrazosulfuron-ethyl on Fluiseed

TABLE 207A 2 evaluation of the actual control and combination of fenoxaprop-p-ethyl on large crabgrass

Table 208A 2 evaluation of actual control and combined action of cyhalofop-butyl on crab grass

TABLE 209 evaluation of actual prevention and combination of prometryn-A2 for Alismatis rhizoma

TABLE 210A 2 evaluation of actual prevention and combination of Xicaojing with Alisma orientale

TABLE 211A 2 evaluation of actual control and combination of bromoxynil octanoate on ludwigia prostrata

TABLE 212 evaluation of actual prevention and combination of Flufotiapyr-methyl and Alismatis rhizoma with A2 mixture

TABLE 213A 2 evaluation of the actual control and combination of the Benthiazamide on Fluoritum

TABLE 214A 2 evaluation of the actual control and combination of Fluoritan with tetrazolyl oxamide

TABLE 215A 2 evaluation of the actual control and combination of fluroxypyr-meptyl ester as a blended ingredient for syringy knotweed

TABLE 216 evaluation of actual prevention and combination of Alisma orientale by compounding 2, 4-Dichlorophenoxyacetic acid with A2

TABLE 217A 2 evaluation of the actual control and combination of asulam to large crabgrass

TABLE 218A 2 evaluation of the actual control and Combined Effect of Tetflupyrolomet on crab

TABLE 219 evaluation of actual prevention and combination of Fenoxasulfolane with Alismatis rhizoma by compounding with Feroxasulfolane in A2

TABLE 220A 2 compoundingEvaluation of actual prevention effect and combined action of alisma orientale

TABLE 221A 2 compoundingEvaluation of actual prevention effect and combined action of alisma orientale

TABLE 222A 2 evaluation of the actual prevention and combination of Dimesufazet for Fluoritum

Table 223A 2 evaluation of actual control effect and combined effect of Ephrifenacil mixed with fluorescent strip

C) Demonstration of field

The herbicidal compositions prepared in examples 1 to 68 were used for field weed effect tests. An exemplary promotional trial was conducted in 2017 at the Jiangxi Poyang test point. The weeds in the field are mainly: barnyard grass, moleplant seed, monochoria vaginalis, cyperus rotundus, ludwigia prostrata and the like.

The test method comprises the following steps: treating stem and leaf until the weeds are in the 2-3 leaf stage, manually spraying with a sprayer, and adding water with the amount of 30 kg/667 m²The stem and leaf are sprayed evenly. The specific test agents and dosages are detailed in table 224, with a cell area of 20 square meters, repeated 3 times per treatment. The control effect 20 days after application is shown in Table 224.

Table 224 shows exemplary field effects of the formulated compositions

Through a large number of tests and explorations, the invention unexpectedly discovers that the composition is used for preventing and killing weeds such as heterotype nutgrass flatsedge, cyperus rotundus, monochoria vaginalis, barnyard grass, edible tulip, japanese iris, ludwigia prostrata, digitaria sanguinea, rhizoma alismatis, barnyard grass, moleplant seed and the like, has a surprising and unexpected synergistic effect, is more obvious in performance under low dosage, can reduce the dosage and the pollution to the environment, is reasonably compounded, reduces the agricultural cost, is efficient to ALS and ACCase inhibitor resistant weeds, and has a good application prospect. Meanwhile, the herbicide composition shows good selectivity and excellent synergistic effect in wheat fields, corn fields, paddy fields, peanuts, sugarcane, sorghum, millet, potatoes, rape, soybeans, cotton, vegetables, bluegrass, tall fescue, zoysia japonica and other plants through tests, and can be developed into herbicide mixtures with wide market value.