阅读说明：本技术 一种完全湿性愈合的抗感染物理方法 (Anti-infection physical method for complete wet healing ) 是由 岳晋君 张奇 刘欢莲 于 2020-12-11 设计创作，主要内容包括：本发明提供了一种完全湿性愈合的抗感染物理方法。该抗感染物理方法包括：(1)高电位,增强凝血酶活性,加快纤维蛋白酶去掉电子,形成纤维蛋白,阻挡聚集血小板,快速形成血凝块；同时形成高电势梯度,促进生长因子受体与因子结合、促进细胞加速分裂、促进组织修复。本发明护理时创造接近生理状态的完全湿性愈合环境,就有利于止血止疼、肉芽的生长,便于皮肤细胞的分裂,从而促使伤口的完整愈合；1100mv以上的高电位和正电荷,接触到微生物的瞬间,夺取电子,干扰其膜的平衡,改变了细胞膜内外电位差、膜的通透性和膜内外的渗透压,穿透细胞膜引起细胞膜的破裂,细胞质外溢以及超微结构的改变,从而电死病菌,不会导致耐药性,反复使用效果不会降低。(The present invention provides a physical method of infection resistance for total wet healing. The anti-infective physical method comprises: (1) the high potential enhances the activity of thrombin, accelerates the removal of electrons by the fibrin, forms fibrin, blocks platelet aggregation and quickly forms blood clots; meanwhile, a high potential gradient is formed, so that the combination of a growth factor receptor and a factor is promoted, the accelerated division of cells is promoted, and the tissue repair is promoted. The invention creates a completely wet healing environment close to the physiological state during nursing, is beneficial to stopping bleeding and pain, promoting the growth of granulation and facilitating the division of skin cells, thereby promoting the complete healing of wounds; the high potential and positive charge above 1100mv capture electrons at the moment of contacting with microbes, disturb the balance of the membrane, change the potential difference inside and outside the cell membrane, the permeability of the membrane and the osmotic pressure inside and outside the membrane, penetrate the cell membrane to cause the rupture of the cell membrane, the overflow of cytoplasm and the change of the ultrastructure, thereby electrocuting the germs, causing no drug resistance and not reducing the repeated use effect.)

1. A completely wet healing anti-infective physical method characterized by: the anti-infective physical method comprises:

(1) the high potential is over 1100mv, the activity of thrombin is enhanced, the removal of electrons by the fibrin is accelerated, fibrin is formed, platelet aggregation is prevented, and blood clots are quickly formed; meanwhile, a high potential gradient is formed, so that the combination of a growth factor receptor and a factor is promoted, the accelerated division of cells is promoted, and the tissue repair is promoted;

(2) the positive charge has anti-infection performance, and can capture pathogenic microorganism electrons instantly, change membrane osmotic pressure, and pierce a biological membrane to inactivate a slightly acidic environment;

(3) hydrogen ions form a slightly acidic environment, so that a hydrogen ion biomembrane is formed, a slightly acidic environment is produced, macrophages are stimulated to produce angiogenesis factors, the growth of fibroblasts is promoted, and the growth of blood vessels is stimulated; meanwhile, pathogenic microorganisms lose the living environment;

(4) active oxygen can regulate the oxidation tension of the wound surface, form a hydrogen ion biomembrane, create a slightly acidic environment, stimulate macrophages to produce angiogenesis factors, promote the growth of fibroblasts and stimulate the growth of blood vessels; meanwhile, pathogenic microorganisms can be inactivated;

(5) the sterile ionic solution provides proper moisture for wound cells; accelerating cell arrangement, avoiding scar growth and accelerating wound healing;

(6) the slightly acid moist environment, the continuous biological membrane protection, the complete moist environment of the wound surface, the continuous action, the complete wound healing.

2. The anti-infective physical method of total wet healing according to claim 1, wherein the anti-infective physical method comprises: the physiological process of wound healing is mainly shown in the following aspects:

(1) blood coagulation;

(2) resisting infection;

(3) reducing inflammatory mediator pain;

(4) regeneration of cellular blood vessels;

(5) proliferation of immune cells;

(6) the cells swim;

(7) the scar is reduced;

(8) the wound heals completely.

3. The anti-infective physical method of total wet healing according to claim 1, wherein the anti-infective physical method comprises: the voltage of the high potential in the method (1) is more than 1100 mv.

Technical Field

The invention belongs to the technical field of wound healing, and particularly relates to an anti-infection physical method for complete wet healing.

Background

The epithelial cells need to grow rapidly under the wet mixed well, under the environment, the release of various growth factors for promoting wound healing is facilitated, the cell proliferation is stimulated, the cell activity is maintained, the contents of fibroblast growth factors, epidermal growth factors, platelet-derived growth factors and the like in wound exudate are higher than those in a non-wet environment, and the exudate can also promote the growth of fibroblasts, keratinocytes and endothelial cells cultured in vitro.

The traditional medicine has the side effects of medicines, medicine residues, deviation of effective fruits, incomplete wet healing, scabbing and high scar probability when the traditional medicine interferes with healing wounds, and in addition, the antibiotics kill the bacteria to cause drug resistance when the traditional medicine is used, and the effect is greatly reduced when the traditional medicine is repeatedly used.

Disclosure of Invention

In view of the above, the present invention is directed to a physical method of infection resistance for fully wet healing. The anti-infection physical method for completely moist healing has the advantages of physical anti-infection, drug resistance, no residue, no chemical addition, easy biodegradation and low cost, and solves the problems that the existing chemical anti-infection agent and the accelerating wet healing agent can not be combined, are difficult to biodegrade, have poor compatibility, large side effect and high cost.

In order to achieve the purpose, the technical scheme of the invention is realized as follows: a completely wet healing anti-infective physical method, comprising:

(1) the high potential enhances the activity of thrombin, accelerates the removal of electrons by the fibrin, forms fibrin, blocks platelet aggregation and quickly forms blood clots; meanwhile, a high potential gradient is formed, so that the combination of a growth factor receptor and a factor is promoted, the accelerated division of cells is promoted, and the tissue repair is promoted;

(2) the positive charge has anti-infection performance, and can capture pathogenic microorganism electrons instantly, change membrane osmotic pressure, and pierce a biological membrane to inactivate a slightly acidic environment;

(3) hydrogen ions form a slightly acidic environment, so that a hydrogen ion biomembrane is formed, a slightly acidic environment is produced, macrophages are stimulated to produce angiogenesis factors, the growth of fibroblasts is promoted, and the growth of blood vessels is stimulated; meanwhile, pathogenic microorganisms lose the living environment;

(4) active oxygen can regulate the oxidation tension of the wound surface, form a hydrogen ion biomembrane, create a slightly acidic environment, stimulate macrophages to produce angiogenesis factors, promote the growth of fibroblasts and stimulate the growth of blood vessels; meanwhile, pathogenic microorganisms can be inactivated;

(5) the sterile ionic solution provides proper moisture for wound cells; accelerating cell arrangement, avoiding scar growth and accelerating wound healing;

(6) the slightly acid moist environment, the continuous biological membrane protection, the complete moist environment of the wound surface, the continuous action, the complete wound healing.

Further, the physiological process of wound healing is mainly expressed in the following aspects:

(1) blood coagulation;

(2) resisting infection;

(3) reducing inflammatory mediator pain;

(4) regeneration of cellular blood vessels;

(5) proliferation of immune cells;

(6) the cells swim;

(7) the scar is reduced;

(8) the wound heals completely.

Further, the high potential is more than 1100 mv.

Compared with the prior art, the anti-infection physical method for completely wet healing has the following advantages:

1. the invention creates a complete wet healing condition close to the physiological state during nursing, which is beneficial to resisting infection, stopping bleeding and pain, promoting the growth of granulation and facilitating the division of skin cells, thereby promoting the complete healing of wounds;

2. the high potential of the invention is more than 1100mv, capture electrons at the moment of contacting with the microorganism, disturb the balance of the membrane, change the potential difference inside and outside the cell membrane, the permeability of the membrane and the osmotic pressure inside and outside the membrane, penetrate the cell membrane to cause the rupture of the cell membrane, the cytoplasm overflows and the change of the ultramicro structure, thereby electrocuting the germ without causing drug resistance and reducing the repeated use effect;

3. the invention has the advantages of rapid blood coagulation, anti-infection, enhancement of the binding capacity of healing factors, acceleration of cell division and growth, improvement of immunity, reduction of scars and promotion of wound healing.

Drawings

FIG. 1 is a diagram of the surface model of "electrocuted" bacteria according to the present invention;

FIG. 2 is a report of data from clinical trials of "electrocuted" bacteria according to the present invention;

FIG. 3 is a schematic diagram of the completely wet healing of the present invention.

Detailed Description

The present invention will be described in detail with reference to examples.

A completely wet healing anti-infective physical method, comprising:

(1) the high potential enhances the activity of thrombin, accelerates the removal of electrons by the fibrin, forms fibrin, blocks platelet aggregation and quickly forms blood clots; meanwhile, a high potential gradient is formed, so that the combination of a growth factor receptor and a factor is promoted, the accelerated division of cells is promoted, and the tissue repair is promoted;

(2) the positive charge has anti-infection performance, and can capture pathogenic microorganism electrons instantly, change membrane osmotic pressure, and pierce a biological membrane to inactivate a slightly acidic environment;

(3) hydrogen ions form a slightly acidic environment, so that a hydrogen ion biomembrane is formed, a slightly acidic environment is produced, macrophages are stimulated to produce angiogenesis factors, the growth of fibroblasts is promoted, and the growth of blood vessels is stimulated; meanwhile, pathogenic microorganisms lose the living environment;

(4) active oxygen can regulate the oxidation tension of the wound surface, form a hydrogen ion biomembrane, create a slightly acidic environment, stimulate macrophages to produce angiogenesis factors, promote the growth of fibroblasts and stimulate the growth of blood vessels; meanwhile, pathogenic microorganisms can be inactivated;

(5) the sterile ionic solution provides proper moisture for wound cells; accelerating cell arrangement, avoiding scar growth and accelerating wound healing;

(6) the slightly acid moist environment, the continuous biological membrane protection, the complete moist environment of the wound surface, the continuous action, the complete wound healing.

In this embodiment, the physiological process of wound healing is mainly shown in the following aspects:

(1) blood coagulation;

(2) resisting infection;

(3) reducing inflammatory mediator pain;

(4) regeneration of cellular blood vessels;

(5) proliferation of immune cells;

(6) the cells swim;

(7) the scar is reduced;

(8) the wound heals completely.

In the embodiment, a completely wet healing environment close to a physiological state is created during nursing, so that the nursing bed is beneficial to stopping bleeding and pain, promoting granulation growth and facilitating skin cell division, and further promoting complete healing of wounds.

In the embodiment, the high potential is more than 1100mv, electrons are captured at the moment of contacting with the microorganisms, the balance of the membrane is disturbed, the potential difference inside and outside the membrane, the permeability of the membrane and the osmotic pressure inside and outside the membrane are changed, the membrane is penetrated to cause the rupture of the membrane, the overflow of cytoplasm and the change of the ultrastructure, so that the germs are electrocuted, the drug resistance cannot be caused, and the repeated use effect cannot be reduced.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.