阅读说明：本技术 一种含苯唑草酮、异噁唑草酮和氨唑草酮的除草剂组合物 (Herbicide composition containing topramezone, isoxaflutole and amicarbazone ) 是由 于晓静 张建建 吴磊 李玉艳 王祥传 李洪侠 张帅 于 2020-11-09 设计创作，主要内容包括：本发明涉及农药技术领域,具体涉及一种含苯唑草酮、异噁唑草酮和氨唑草酮的除草剂组合物。其活性组分由苯唑草酮、异噁唑草酮和氨唑草酮按照质量比为1-8:5-30:10-30组成。三种活性成分复配具有明显的增效作用,能够减少农药的使用量,降低用药成本,还能延缓杂草的抗药性,扩大防除谱,同时提高对作物的使用安全性。(The invention relates to the technical field of pesticides, and particularly relates to a herbicide composition containing topramezone, isoxaflutole and amicarbazone. The active components of the topramezone-containing compound comprise topramezone, isoxaflutole and amicarbazone according to the mass ratio of 1-8:5-30: 10-30. The compounding of the three active ingredients has obvious synergistic effect, can reduce the use amount of pesticides, reduce the pesticide cost, delay the drug resistance of weeds, expand the prevention and control spectrum and improve the use safety of crops.)

1. The herbicide composition containing topramezone, isoxaflutole and amicarbazone is characterized in that the active components of the herbicide composition consist of topramezone, isoxaflutole and amicarbazone according to the mass ratio of 1-8:5-30: 10-30.

2. The herbicide composition containing topramezone, isoxaflutole and amicarbazone as claimed in claim 1, wherein the active components thereof consist of topramezone, isoxaflutole and amicarbazone in a mass ratio of 3:10: 15.

3. The herbicidal composition comprising topramezone, isoxaflutole, and amicarbazone according to claim 1, wherein the herbicidal composition is formulated as one of a dispersible oil-based suspension, a suspension, or granules.

4. The herbicidal composition comprising topramezone, isoxaflutole and amicarbazone according to claim 3, wherein the formulation is a dispersible oil-suspendable formulation.

5. The herbicide composition containing topramezone, isoxaflutole and amicarbazone according to claim 4, wherein the dispersible oil-based suspension agent comprises the following components: 20-50% of active ingredients, 5-15% of emulsifying agents, 4-8% of dispersing agents, 1-5% of wetting agents, 3-5% of thickening agents, 3-10% of anti-freezing agents and the balance of dispersing media.

6. The herbicide composition containing topramezone, isoxaflutole and amicarbazone according to claim 5, wherein the dispersant is prepared by mixing a sodium polycarboxylate salt and calcium lignosulfonate in a mass ratio of 1-1.5: 1; emulsifier Tween-60 #; the wetting agent is sodium dodecyl sulfate; the thickening agent is formed by mixing bentonite and xanthan gum according to the mass ratio of 1-2: 1; the antifreezing agent is propylene glycol; the dispersion medium is methyl esterified vegetable oil.

7. Use of a herbicidal composition comprising topramezone, isoxaflutole and amicarbazone according to any one of claims 1 to 6 for the control of weeds in corn fields.

Technical Field

The invention relates to the technical field of pesticides, and particularly relates to a herbicide composition containing topramezone, isoxaflutole and amicarbazone.

Background

With the improvement of the drug resistance of weeds, the use of a single herbicide cannot achieve ideal weeding effect, and the development of reasonable binary compound and ternary compound preparations is beneficial to reducing the use of pesticides and improving the drug effect.

Topramezone, an English name, a chemical name of [3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4- (methylsulfonyl) phenyl ] (5-hydroxy-1-methyl-1H-pyrazol-4-yl) ketone (shown in the following formula) is a contact-killing type selective herbicide, under the condition of light, in the chlorophyll biosynthesis process, topramezone can inhibit protoporphyrinogen oxidase to cause the accumulation of toxic intermediates, so that the cell membranes of weeds are damaged, the leaves are rapidly dried and dead, carfentrazone is easily absorbed and is slightly influenced by severe weather, and the weeds die after 2-4 days of application.

Isoxaflutole, having the english name isoxaflutole and the chemical name 5-cyclopropyl-1, 2-oxazol-4-yl-a, a, a-trifluoro-2-methylhydrazinesulfonyl-p-toluenone (formula below). The isoxaflutole belongs to a p-hydroxyphenylpyruvate dioxygenase inhibitor, namely an HPPD inhibitor, and the synthesis of the p-hydroxyphenylpyruvate dioxygenase is inhibited, so that the accumulation of tyrosine is caused, the biosynthesis of plastoquinone and tocopherol is hindered, the biosynthesis of carotene is further influenced, and the weed is whitened and died. The isoxaflutole has wide herbicidal spectrum and can be used before and after seedling. However, there is a risk of crop safety, for example, in 1999, in the united states, when isoxaflutole is used to control 400 million hectares of corn, there is a phytotoxicity in about 6% to 7% of the area, so that rational formulation can improve the safety of the product to crops.

Amicarbazone, the english name is amicarbazone, the chemical name is: 4-amino-5-oxo-3-isopropyl-N-tert-butyl-1, 2, 4-triazole-1-carboxamide (see formula below) is a triazolinone herbicide. The action mechanism is that protoporphyrinogen oxidase in the chlorophyll biosynthesis process is inhibited to cause cell membrane damage, so that leaves are rapidly dried and dead. The amicarbazone can be used for soil treatment, stem leaf spraying, root system and leaf surface absorption, and can be used for preventing and treating corn field, sugarcane field and lawn

The above annual broadleaf weeds and gramineous weeds.

The reasonable mixing of the herbicides is an effective measure for improving the field weeding effect of the herbicides and delaying the occurrence and development of the drug resistance of the herbicides, and the applicant finds that no composite patent of the combination of topramezone, isoxaflutole and amicarbazone exists at present through search. Meanwhile, tests prove that the three components have obvious synergistic effect, the control effect on weeds in corn and sugarcane fields is obviously improved, the weed control spectrum is expanded, the dosage is reduced, the control and medication cost is reduced, and the safety on crops is improved.

Disclosure of Invention

Aiming at the problems in the prior art, the invention provides the herbicide composition containing topramezone, isoxaflutole and amicarbazone, and the three active ingredients are compounded to have obvious synergistic action, so that the control spectrum is enlarged, and the use safety of crops is improved.

The technical scheme of the invention is as follows:

the active components of the herbicide composition comprise topramezone, isoxaflutole and amicarbazone according to the mass ratio of 1-8:5-30: 10-30.

Preferably, the active component of the topramezone-containing compound comprises topramezone, isoxaflutole and amicarbazone according to the mass ratio of 3:10: 15.

The weeding composition can be prepared into one of dispersible oil suspending agent, suspending agent or granules.

The preferred formulation is a dispersible oil suspension formulation.

The dispersible oil suspending agent comprises the following components: 20-50% of active ingredients, 5-15% of emulsifying agents, 4-8% of dispersing agents, 1-5% of wetting agents, 3-5% of thickening agents, 3-10% of anti-freezing agents and the balance of dispersing media.

Preferably, the dispersing agent is formed by mixing sodium polycarboxylate and calcium lignosulfonate according to the mass ratio of 1.5: 1; emulsifier Tween-60 #; the wetting agent is sodium dodecyl sulfate; the thickening agent is formed by mixing bentonite and xanthan gum according to the mass ratio of 1.2: 1; the antifreezing agent is propylene glycol; the dispersion medium is methyl esterified vegetable oil.

The dispersing agent, the emulsifying agent, the wetting agent, the thickening agent, the antifreezing agent and the dispersion medium in the formula are subjected to high-speed shearing and uniform mixing, the topramezone, the isoxaflutole and the amicarbazone are added, the high-speed shearing and dispersion are carried out, and the sand mill is used for sanding to prepare the dispersible oil suspending agent containing the topramezone, the isoxaflutole and the amicarbazone.

The weeding composition can be used for preventing and treating weeds in corn fields such as large crabgrass, green bristlegrass herb, purslane, cocklebur or quinoa and the like.

Chemical weeding in corn fields mainly adopts post-emergence stem and leaf treatment, most of the prior stem and leaf treatment agents have certain requirements on the growth period of corn and the age of weeds and grasses in the using process, and otherwise, the prevention and control effects are poor and phytotoxicity is easy to generate. The active components, dosage and application period of the weeding mixture have important influence on the safety of crops and the control effect of weeds.

The beneficial effect of the invention is that,

according to the herbicide composition containing topramezone, isoxaflutole and amicarbazone, provided by the invention, the three active ingredients are compounded to have an obvious synergistic effect, so that the use amount of pesticides can be reduced, the drug cost is reduced, the drug resistance of weeds can be delayed, the control spectrum is expanded, and the use safety of crops is improved.

Detailed Description

In order to make those skilled in the art better understand the technical solutions in the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A weeding composition containing topramezone, isoxaflutole and amicarbazone comprises the following components in percentage by mass: 2% of topramezone, 7% of isoxaflutole, 14% of amicarbazone, 3% of sodium polycarboxylate, 3% of calcium lignosulfonate, 10% of tween-60 #, 1% of sodium dodecyl sulfate, 2% of bentonite, 1% of xanthan gum, 3% of propylene glycol and the balance of methyl esterified vegetable oil.

The dispersible oil suspension agent containing topramezone, isoxaflutole and amicarbazone is prepared by uniformly shearing and mixing the dispersing agent, the emulsifying agent, the wetting agent, the thickening agent, the antifreezing agent and the methyl esterified vegetable oil in the formula at a high speed, adding topramezone, isoxaflutole and amicarbazone, shearing and dispersing at a high speed, and sanding by using a sand mill.

Example 2

A weeding composition containing topramezone, isoxaflutole and amicarbazone comprises the following components in percentage by mass: 3% of topramezone, 10% of isoxaflutole, 15% of amicarbazone, 4% of sodium polycarboxylate, 3% of calcium lignosulfonate, 10% of tween-60 #, 2% of sodium dodecyl sulfate, 2% of bentonite, 1% of xanthan gum, 4% of propylene glycol and the balance of methyl esterified vegetable oil.

The preparation method is the same as example 1.

Example 3

A weeding composition containing topramezone, isoxaflutole and amicarbazone comprises the following components in percentage by mass: 3% of topramezone, 14% of isoxaflutole, 24% of amicarbazone, 2% of sodium polycarboxylate, 2% of calcium lignosulfonate, 15% of tween-60 #, 4% of sodium dodecyl sulfate, 2% of bentonite, 1% of xanthan gum, 8% of propylene glycol and the balance of methyl esterified vegetable oil.

The preparation method is the same as example 1.

Example 4

A weeding composition containing topramezone, isoxaflutole and amicarbazone comprises the following components in percentage by mass: 8% of topramezone, 22% of isoxaflutole, 14% of amicarbazone, 3% of sodium polycarboxylate, 2% of calcium lignosulfonate, 5% of tween-60 #, 2% of sodium dodecyl sulfate, 2% of bentonite, 2% of xanthan gum, 3% of propylene glycol and the balance of methyl esterified vegetable oil.

The preparation method is the same as example 1.

Example 5

A topramezone-containing weeding composition comprises the following components in percentage by mass: 2% of topramezone, 16% of isoxaflutole, 30% of amicarbazone, 3% of sodium polycarboxylate, 2% of calcium lignosulfonate, 7% of tween-60 #, 3% of sodium dodecyl sulfate, 1% of bentonite, 1% of xanthan gum, 4% of propylene glycol and the balance of methyl esterified vegetable oil.

The preparation method is the same as example 1.

Comparative example 1

A weeding composition comprises the following components in percentage by mass: 10% of isoxaflutole, 15% of topramezone, 3% of sodium polycarboxylate, 2% of calcium lignosulfonate, 10% of tween-60 #, 1% of sodium dodecyl sulfate, 2% of bentonite, 1% of xanthan gum, 5% of propylene glycol and the balance of methyl esterified vegetable oil.

Uniformly shearing and mixing the dispersing agent, the emulsifying agent, the wetting agent, the thickening agent, the antifreezing agent and the methyl esterified vegetable oil in the formula at a high speed, adding isoxaflutole and amicarbazone, shearing and dispersing at a high speed, and sanding by using a sand mill to prepare the dispersible oil suspending agent containing isoxaflutole and topramezone.

Comparative example 2

A weeding composition comprises the following components in percentage by mass: 15% of amicarbazone, 3% of topramezone, 3% of sodium polycarboxylate, 2% of calcium lignosulfonate, 10% of tween-60 #, 1% of sodium dodecyl sulfate, 2% of bentonite, 1% of xanthan gum, 5% of propylene glycol and the balance of methyl-esterified vegetable oil.

Uniformly shearing and mixing the dispersing agent, the emulsifying agent, the wetting agent, the thickening agent, the antifreezing agent and the methyl esterified vegetable oil in the formula at a high speed, adding isoxaflutole and amicarbazone, shearing and dispersing at a high speed, and sanding by using a sand mill to prepare the dispersible oil suspending agent containing isoxaflutole and topramezone.

Test examples

Example of field efficacy test: and (4) field efficacy test for preventing and removing annual weeds in the corn field.

Test agents and application doses: the dispersible oil suspending agent prepared in the examples 1-5 and the herbicide prepared in the comparative examples 1-2 are selected, and 4% of topramezone dispersible oil suspending agent, 26% of isoxaflutole dispersible oil suspending agent and 30% of amicarbazone dispersible oil suspending agent are independently used, and the dosage of active ingredients per mu is 4 g.

Test site: binzhou city, Boxing county, Shandong province.

The main grass phases in the field are as follows: green bristlegrass herb, siberian cocklebur fruit, purslane, large crabgrass herb and chenopodium glaucum. In the 3-5 leaf stage of corn and the 3-4 leaf stage of weed, the weeding composition is mixed with 30 liters of water per mu according to the dosage of the preparation per mu, and the mixture is sprayed on the stem leaves of the whole field uniformly. According to the investigation result, the fresh weight control effect of the weeds is calculated, and the specific result is shown in table 1.

The combined action evaluation method comprises the following steps: the herbicide combinations were evaluated according to Colby, which is formulated as follows:

E₀＝A×B×C/100²，

wherein the content of the first and second substances,

a: (ii) the actual deterrent value of topramezone used in a single dose at a certain dosage;

b: the actual deterrent value of isoxaflutole at a dose when used as a single dose;

c: (ii) the actual deterrent value of amicarbazone at a dose when used as a single dose;

E₀: theoretical prevention values of topramezone, isoxaflutole and amicarbazone when used in a mixed manner;

e: the actual prevention value of the topramezone, the isoxaflutole and the amicarbazone during mixing;

evaluation criteria: when E-E₀When the content is more than 10 percent, the synergistic effect is shown; when-10% < E-E₀When the concentration is less than 10%, the additive effect is shown; when E-E₀When the content is less than-10%, antagonism is shown. The test results are shown in Table 2.

Analysis and discussion of test results:

TABLE 1 field test results of annual weed control in corn field (21 days after application)

Tests show that the average control effect of the three effective component weeding compositions on annual weeds in corn fields reaches above 87.27%, the three effective component weeding compositions are obviously better than that of a comparative example and a single agent, the synergistic effect is obvious, the weeding spectrum is expanded, adverse phenomena such as yellowing, curling and whitening of the corn are not caused during the test, and the fact that the three agents are mixed has certain safety on the corn is demonstrated.

TABLE 2 results of topramezone, isoxaflutole, amicarbazone and combinations thereof on the control of eleusine

Compared with the single use of the topramezone, the isoxaflutole and the amicarbazone, the mixed topramezone, the isoxaflutole and the amicarbazone have very good control effect on the eleusine indica, have obvious synergistic effect and are worthy of popularization and application in production.

Although the present invention has been described in detail by way of preferred embodiments, the present invention is not limited thereto. Various equivalent modifications or substitutions can be made on the embodiments of the present invention by those skilled in the art without departing from the spirit and scope of the present invention, and these modifications or substitutions are within the scope of the present invention/any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.