阅读说明：本技术 一种含有二甲氨基二硫代甲酸钠的杀线虫颗粒剂及其制备方法 (Nematicidal granules containing sodium dimethyldithiocarbamate and preparation method thereof ) 是由 张文树 张少飞 唐兴敏 王成彬 高永民 任丽颖 李影 柴方堃 贾成国 于 2020-11-13 设计创作，主要内容包括：本发明公开了一种含有二甲氨基二硫代甲酸钠的杀线虫颗粒剂及其制备方法,按质量百分比计算,包括如下原料:二甲氨基二硫代甲酸钠原药1～20%,氟吡菌酰胺原药：1～20%,溶剂：0.1～20%,成膜剂Ⅰ：0.1～5%,成膜剂Ⅱ：0.1～5%,载体：余量,本发明可与种子同施,且不会影响种子发芽,而且杀线虫持效期长。(The invention discloses a nematicidal granule containing sodium dimethyldithiocarbamate and a preparation method thereof, and the nematicidal granule comprises the following raw materials by mass percent, 1-20% of sodium dimethyldithiocarbamate and fluopyram: 1-20%, solvent: 0.1-20%, film-forming agent I: 0.1-5%, film-forming agent II: 0.1-5%, carrier: and the invention can be applied with the seeds simultaneously, does not affect the germination of the seeds, and has long duration of killing the nematodes.)

1. A nematicidal granule containing sodium dimethyldithiocarbamate, which is characterized in that: the composition comprises 1-20% of a sodium dimethyldithiocarbamate technical material and a fluopyram technical material by mass percent: 1-20%, solvent: 0.1-20%, film-forming agent I: 0.1-5%, film-forming agent II: 0.1-5%, carrier: and (4) the balance.

2. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 1, wherein: the effective components of the granules are sodium dimethyldithiocarbamate and fluopyram.

3. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 2, wherein: the mass ratio of the effective components of sodium dimethyldithiocarbamate to fluopyram is 1: 0.05-20.

4. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 3, wherein: the mass ratio of the effective component sodium dimethyldithiocarbamate to the fluopyram is 10: 2.

5. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 1, wherein: the solvent is absolute ethyl alcohol.

6. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 1, wherein: the film forming agent I is polyvinyl alcohol.

7. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 1, wherein: the film forming agent II is polyvinylpyrrolidone.

8. The nematicidal granule comprising sodium dimethyldithiocarbamate according to claim 1, wherein: the carrier is porous red sand which is formed by processing, granulating, high-temperature burning and swelling and crushing clay, and the surface and the inside of the carrier are provided with a plurality of pores, so that the adsorption capacity is strong.

9. A preparation method of nematicidal granules containing sodium dimethyldithiocarbamate is characterized in that: the method comprises the following steps:

(1) dissolving sodium dimethyldithiocarbamate and film-forming agent I polyvinyl alcohol by using solvent absolute ethyl alcohol according to weight percentage, adding the dissolved solution into carrier red sand, uniformly stirring, and simultaneously air-drying by cold air for later use;

(2) according to the weight percentage, the fluopyram raw pesticide is airflow crushed to D90 of 10 mu m for standby;

(3) dissolving film-forming agent II polyvinylpyrrolidone in water according to weight percentage, pouring into the porous red sand air-dried in the step (1), uniformly stirring, then pouring the crushed fluopyram raw material, continuously stirring, simultaneously air-drying with cold air, stirring to uniformly adhere the medicinal powder on the surface of the porous red sand, and obtaining the finished product.

Technical Field

The invention relates to a nematicidal granule containing sodium dimethyldithiocarbamate and a preparation method thereof, belonging to the technical field of pesticide compositions and preparation thereof.

Background

The sodium dimethyldithiocarbamate is a carbamate bactericide, has good nematicidal activity, is decomposed into methyl isothiocyanate with high toxicity in wet soil, has high toxicity to plant seedlings and seeds, is covered by a film after drip irrigation in the conventional use, fumigates soil, and seeds are sown after the soil is completely drained. The use process is complicated, plastic pollution is generated, and certain toxicity is caused to human bodies.

Fluopyram is a succinate dehydrogenase inhibitor with low toxicity, can interfere the respiration of nematodes, rapidly reduces the activity of the nematodes, shows obviously different mobility in soil, can be slowly and uniformly distributed on the upper layer in the soil, and cannot kill the nematodes in the soil for a long time.

Therefore, a nematicidal granule which can kill the nematodes in the soil for a long time, has small environmental pollution and low toxicity is needed.

Disclosure of Invention

The invention aims to solve the technical problem of providing the nematicidal granules containing the sodium dimethyldithiocarbamate and the preparation method thereof, and the sodium dimethyldithiocarbamate and the fluopyram are compounded for use, so that the quick-acting property and the lasting period of the product for killing the insects are improved, the use method is simplified, and the harm to human bodies and unnecessary pollution are reduced.

In order to solve the technical problems, the technical scheme adopted by the invention is as follows:

the nematicidal granules containing the sodium dimethylaminodithiocarboxylate comprise, by mass, 1-20% of a sodium dimethylaminodithiocarboxylate raw material and 1-20% of a fluopyram raw material: 1-20%, solvent: 0.1-20%, film-forming agent I: 0.1-5%, film-forming agent II: 0.1-5%, carrier: and (4) the balance.

The technical scheme of the invention is further improved as follows: the effective components of the granules are sodium dimethyldithiocarbamate and fluopyram.

The technical scheme of the invention is further improved as follows: the mass ratio of the effective components of sodium dimethyldithiocarbamate to fluopyram is 1: 0.05-20.

The technical scheme of the invention is further improved as follows: the mass ratio of the effective component sodium dimethyldithiocarbamate to the fluopyram is 10: 2.

The technical scheme of the invention is further improved as follows: the solvent is absolute ethyl alcohol.

The technical scheme of the invention is further improved as follows: the film forming agent I is polyvinyl alcohol.

The technical scheme of the invention is further improved as follows: the film forming agent II is polyvinylpyrrolidone.

The technical scheme of the invention is further improved as follows: the carrier is porous red sand which is formed by processing, granulating, high-temperature burning and swelling and crushing clay, has more pores on the surface and inside, has strong adsorption capacity, and can be crushed into particles with the particle size or density similar to that of the seeds applied at the same time.

The technical scheme of the invention is further improved as follows: the method comprises the following steps:

(1) dissolving sodium dimethyldithiocarbamate and film-forming agent I polyvinyl alcohol by using solvent absolute ethyl alcohol according to weight percentage, adding the dissolved solution into carrier red sand, uniformly stirring, and simultaneously air-drying by cold air for later use;

(2) according to the weight percentage, the fluopyram raw pesticide is airflow crushed to D90 of 10 mu m for standby;

(3) dissolving film-forming agent II polyvinylpyrrolidone in water according to weight percentage, pouring into the porous red sand air-dried in the step (1), uniformly stirring, then pouring the crushed fluopyram raw material, continuously stirring, simultaneously air-drying with cold air, stirring to uniformly adhere the medicinal powder on the surface of the porous red sand, and obtaining the finished product.

Due to the adoption of the technical scheme, the invention has the technical progress that:

1. the nematicidal granules prepared by the invention can be applied together with seeds, at the initial stage of sowing, moist soil enables the film-forming agent II polyvinyl pyrrolidone on the surface of the granules to be opened to release fluopyram, and the nematodes are killed rapidly, while sodium dimethyldithiocarbamate in the granules cannot be released under the protection of the film-forming agent I polyvinyl alcohol; along with the rise of the air temperature, the polyvinyl alcohol of the film forming agent I is gradually dissolved and degraded, after the seeds germinate to strong seedlings, sodium dimethyldithiocarbamate can be slowly released from the interior of the porous red sand particles, and a small amount of methyl isothiocyanate can be slowly decomposed to continuously kill nematodes in the soil, so that the purpose of long-acting protection is achieved.

2. The film forming agent I is polyvinyl alcohol, has good biodegradability, can be degraded by 80% in 40 days, and can be isolated from water at low temperature, so that the speed of decomposing sodium dimethyldithiocarbamate into methyl isothiocyanate can be effectively reduced, the nematode killing aging is prolonged, and the risk of poisoning crops is reduced.

3. The film forming agent II is polyvinylpyrrolidone, has good water solubility, no toxicity to skin, good thermal stability and particle lubricity, and can effectively reduce the shedding rate and degradation of fluopyram.

Detailed Description

The present invention will be described in further detail with reference to the following examples:

in order to solve the problems that sodium dimethyldithiocarbamate needs to be fumigated in advance and poisoned to seeds and the lasting period of fluopyram is prolonged when the sodium dimethyldithiocarbamate is used, the invention provides sodium dimethyldithiocarbamate and fluopyram compound granules which can be applied together with seeds, at the initial stage of sowing, moist soil enables a film-forming agent polyvinyl pyrrolidone on the surface of the granules to be opened to release fluopyram, nematodes are killed quickly, and the sodium dimethyldithiocarbamate in the granules cannot be released under the protection of the film-forming agent polyvinyl alcohol. Along with the rise of the air temperature, the film-forming agent polyvinyl alcohol gradually degrades the dissolving agent, and after the seeds germinate to strong seedlings, sodium dimethyldithiocarbamate can be slowly released from the interior of the porous red sand particles, and a small amount of methyl isothiocyanate can be slowly decomposed to continuously kill nematodes in the soil, so that the purpose of long-acting protection is achieved.

Example 11% Dimethylaminodithioformic acid sodium 20% Fluopyram granules

Weighing the following components in percentage by weight:

the preparation method of the granules comprises the following steps: weighing sodium dimethyldithiocarbamate and a film-forming agent I according to the percentage content, dissolving the sodium dimethyldithiocarbamate and the film-forming agent I by using a proper amount of absolute ethyl alcohol, pouring the mixture into a carrier after the sodium dimethyldithiocarbamate and the film-forming agent I are completely dissolved, continuously stirring the mixture until the liquid and the solid are uniformly mixed, and air-drying the mixture by cold air for standby; dissolving the film forming agent II in water according to the percentage, pouring the solution into air-dried red sand, uniformly stirring, then pouring the fluopyram raw material with the crushed particle size D90-10 mu m, stirring until the surface of the red sand is uniformly adhered with the medicinal powder, and continuously stirring and simultaneously air-drying the red sand by cold wind to prepare the finished product.

Example 220% Dimethylaminodithiocarbamic acid sodium 1% Fluopyram granules

Weighing the following components in percentage by weight:

the preparation is as in example 1.

Example 310% sodium Dimethylaminodithioformate.2% Fluopyram granules

Weighing the following components in percentage by weight:

the preparation is as in example 1.

Comparative example 1 granules of 10% sodium Dimethylaminodithioformate 2% Fluopyram without addition of film I

Weighing the following components in percentage by weight:

the preparation is as in example 1.

Comparative example 2 granules of 10% sodium Dimethylaminodithioformate.2% Fluopyram without addition of film II

Weighing the following components in percentage by weight:

the preparation is as in example 1.

Comparative example 3 film-Forming agent-free 10% sodium Dimethylaminodithioformate.2% Fluopyram granules

Weighing the following components in percentage by weight:

sodium dimethylaminodithiocarboxylate 10%

Fluopyram 2%

Balance of carrier

The preparation is as in example 1.

Experimental example 1 germination percentage experiment

The germination rates of three seeds of wheat, corn and peanut in the simulated soil of a laboratory are tested, and the germination rates are calculated by simultaneously applying the seeds of example 3, comparative example 1, comparative example 2 and comparative example 3.

The experimental method comprises the following steps: respectively selecting a plurality of plump wheat seeds, corn seeds and peanut seeds for later use; digging park sandy soil, selecting surface dishes with different specifications, and sterilizing at high temperature for later use; uniformly spreading sandy soil on a watch glass, sowing seeds in the same hole according to the proportion of 1 seed and 2 medicaments, wherein the number of each cultured seed is not less than 50, spraying sterile water, placing in a constant-temperature incubator, keeping the temperature at 25 ℃, the humidity at 70-80% and culturing for 15 days. Three groups were tested in parallel.

The calculation method comprises the following steps: germination rate%

TABLE 1 germination rates of different seeds

As can be seen from the above table, the germination rate of the experimental group with the two film forming agents is significantly higher than that of the comparative example with no or little film forming agent. Therefore, the film-forming agent is added to effectively prevent the toxicity of the methyl isothiocyanate decomposed from the sodium dimethyldithiocarbamate to the seeds and inhibit the germination of the seeds.

EXAMPLE 2 prevention of nematodes

Experiments are carried out in a greenhouse vegetable planting base in a certain village of Shijiazhuang, the average temperature of the greenhouse is 25 ℃, tomatoes with short growth period are selected as experimental objects in soil fertility, previous crops are cucumbers, and serious insect pests occur along with the lines.

The experimental method comprises the following steps: a total of 5 treatments were set up in the experiment: the seed-drug co-application experiments were carried out using example 3, comparative example 1, comparative example 2, comparative example 3 and the control group, respectively, 5 seeds per well were 5 drugs, and the drug-to-seed interval was kept at 1 cm. The area of each cell is 50 square meters, and is not less than 100 holes. The experiment was repeated 3 times.

Effect investigation:

germination percentage at 10 days was investigated: germination rate%

Investigation of prevention and treatment effects: the method comprises respectively investigating 50 plants in each cell by drawing out the plant and counting the tumors 10 days, 15 days, 30 days and 55 days after the application, and calculating disease index and preventing and treating effect according to the disease degree.

Disease severity grading standard:

level 0: the root is complete without knots;

level 1: a small amount of knots accounts for less than 25%;

and 2, stage: the number of knots accounts for 26-50%;

and 3, level: the number of knots accounts for 51-75%;

4, level: the number of knots is 75-100%.

Disease incidence%

Disease index is the sum of (number of diseased plants at each stage x relative stage value) ÷ (survey total plants x highest stage) × 100

The control effect%

Comparison after administration

TABLE 210 days after germination Experimental data

TABLE 3 comparison of drug effects of different drug treatments

As can be seen from the table above, the agent without the film forming agent not only affects the seed germination, but also has a short duration, and the agent with the film forming agent has a little difference from the quick-acting property of the agent without the film forming agent, but has a long duration and does not affect the seed germination.

Alternative materials for the various components are listed in the description of the invention, but it will be understood by those skilled in the art that: the above list of component materials is not intended to be limiting and non exhaustive, and the various components may be replaced by other equivalent materials not mentioned in the present description, while still achieving the objects of the present invention. The specific embodiments mentioned in the description are to be construed as merely illustrative, and not limitative of the remainder of the disclosure in any way whatsoever.

In addition, the range of the amount of each component of the present invention includes any combination of any lower limit and any upper limit mentioned in the specification, and also includes any range where the specific content of the component in each specific example is made up as a combination of the upper limit or the lower limit: all such ranges are intended to be included within the scope of the present invention for brevity and clarity only and are not intended to be exhaustive or to limit the scope of the invention to the precise forms disclosed. Each feature of the invention described in this specification may be combined with any other feature of the invention which combination is not specifically disclosed in the specification for the sake of brevity.