Mildew-proof traditional Chinese medicine beverage packaging bag and processing method thereof

文档序号：899422 发布日期：2021-02-26 浏览：22次中文

阅读说明：本技术 一种防霉型中药饮品包装袋及其加工方法 (Mildew-proof traditional Chinese medicine beverage packaging bag and processing method thereof ) 是由陈绍武陈泽丽洪美芸于 2020-11-16 设计创作，主要内容包括：本发明公开一种防霉型中药饮品包装袋,包括如下重量份原料：聚合物基质100-200份、马来酸酐接枝聚乙烯5-10份和防霉剂10-12份；该防霉型中药饮品包装袋的加工方法包括如下步骤：第一步、将聚合物基质和马来酸酐接枝聚乙烯搅拌均匀后通过双螺杆挤出机共混,熔融挤出,然后用切粒机切成颗粒,第二步、将第一步制备的颗粒和防霉剂混合均匀后通过单螺杆挤出机与流延机相连,熔融挤出后,制得包装袋薄膜,之后进行分切、制袋,即得一种防霉型中药饮品包装袋；在保证包装袋防霉效果的前提下,偶联剂与微纤化纤维素和线性低密度聚乙烯的双向反应,实现了微纤化纤维素和线性低密度聚乙烯的结合,提高了包装袋的力学性能。(The invention discloses a mildew-proof traditional Chinese medicine beverage packaging bag which comprises the following raw materials in parts by weight: 100-200 parts of polymer matrix, 5-10 parts of maleic anhydride grafted polyethylene and 10-12 parts of mildew preventive; the processing method of the mildew-proof traditional Chinese medicine beverage packaging bag comprises the following steps: uniformly stirring a polymer matrix and maleic anhydride grafted polyethylene, blending through a double-screw extruder, carrying out melt extrusion, cutting into particles by using a granulator, uniformly mixing the particles prepared in the first step and a mildew preventive, connecting the particles with a casting machine through a single-screw extruder, carrying out melt extrusion to obtain a packaging bag film, and then slitting and bag making to obtain the mildew-proof type traditional Chinese medicine beverage packaging bag; on the premise of ensuring the mildew-proof effect of the packaging bag, the coupling agent reacts with the microfibrillated cellulose and the linear low-density polyethylene in a two-way manner, so that the combination of the microfibrillated cellulose and the linear low-density polyethylene is realized, and the mechanical property of the packaging bag is improved.)

1. The mould-proof traditional Chinese medicine beverage packaging bag is characterized by comprising the following raw materials in parts by weight: 100-200 parts of polymer matrix, 5-10 parts of maleic anhydride grafted polyethylene and 10-12 parts of mildew preventive;

the mildew-proof traditional Chinese medicine beverage packaging bag is processed by the following steps:

step one, uniformly stirring a polymer matrix and maleic anhydride grafted polyethylene, blending through a double-screw extruder, melting and extruding, and cutting into particles by using a granulator, wherein the heating temperatures from a first area to an eighth area of the double-screw extruder are that the temperature of the first area of the double-screw extruder is 110-; the rotating speed of the screw is 30-40 r/min;

step two, uniformly mixing the particles prepared in the step one with a mildew preventive, connecting the mixture with a casting machine through a single-screw extruder, carrying out melt extrusion to obtain a packaging bag film, and then slitting and making bags to obtain the mildew-proof traditional Chinese medicine beverage packaging bag; the temperatures of all sections of the single-screw extruder are respectively 170 ℃ for the feeding section 165, 180 ℃ for the melting section 170, 170 ℃ for the metering section 160, 40-50r/min for the rotating speed and 3-4r/min for the rolling speed of the casting machine.

2. The mold-proof packaging bag for Chinese herbal medicine drink as claimed in claim 1, wherein the head temperature of the twin-screw extruder is 150-.

3. The mold-proof Chinese medicinal beverage packaging bag according to claim 1, wherein the polymer matrix is prepared by the following steps:

step S11, adjusting the pH value of 95% ethanol water solution by using glacial acetic acid to 2-4, then adding vinyltriethoxysilane and microfibrillated cellulose, reacting at the temperature of 55-65 ℃ for 2-3h, carrying out vacuum filtration after the reaction is finished, washing the obtained filter residue with deionized water for three times, and freeze-drying the washed filter residue at the low temperature of-70 ℃ for 10-16h to obtain a mixture a;

step S12, mixing the mass ratio of 1: 100, uniformly stirring the mixture a and deionized water to obtain a suspension, and mixing the span 80 and the polyglycerol fatty acid ester according to the mass ratio of 1; 1, adding the mixture into a three-neck flask, stirring for 6-10min under the conditions that the temperature is 40-60 ℃ and the rotating speed is 300-400r/min, then adding the suspension into the three-neck flask, keeping the temperature and the rotating speed unchanged, continuously stirring for 26-30min to obtain an emulsion, and drying the obtained emulsion for 3-5d at 50 ℃ to obtain a mixture b;

step S13, adding the mixture b into dimethylbenzene, stirring for 18-24min at the temperature of 80 ℃ and the rotation speed of 200-300r/min, then adding linear low-density polyethylene, raising the temperature to 140 ℃ and keeping the rotation speed unchanged, continuing stirring for 20-30min, then placing the reaction liquid in a ventilation cabinet for 10-12h to obtain a mixture, washing the mixture for three times by using an ethanol water solution with the volume fraction of 95%, and after washing is finished, drying in vacuum at 80 ℃ to constant weight to obtain a polymer matrix.

4. The mildew-proof traditional Chinese medicine beverage packaging bag according to claim 3, wherein in step S11, the vinyltriethoxysilane accounts for 3-5% of the weight of the microfibrillated cellulose, and the ratio of the amount of the microfibrillated cellulose to the 95% volume fraction ethanol aqueous solution is 1g: 10-15 mL; the mass ratio of the mixture a to the span 80 in the step S12 is 10: 1; the using ratio of the mixture b, the xylene and the linear low density polyethylene in the step S13 is 8-10 g:100mL of: 85 g.

5. The mildew-proof traditional Chinese medicine beverage packaging bag according to claim 1, wherein the mildew-proof agent is prepared by the following steps:

step S22, mixing the emulsion c and the emulsion d obtained in the step S21 according to the mass ratio of 1: 1, mixing, stirring for 5-7min under the conditions that the temperature is 40-50 ℃ and the rotating speed is 4000r/min, then adjusting the pH value of the reaction liquid to 3-4 by using an acetic acid solution, continuing stirring for 30min, stopping heating, naturally cooling to room temperature, then reducing the temperature of the reaction liquid to 2-4 ℃ by using ice water, keeping the temperature unchanged, continuing stirring for 50-60min at the rotating speed of 2000-3000r/min, adjusting the pH value to 8-10 by using a sodium hydroxide solution with the mass fraction of 40% in the stirring process, and obtaining a mixed liquid e after stirring;

6. The mildew-proof traditional Chinese medicine beverage packaging bag according to claim 5, wherein the dosage ratio of gelatin, gum arabic and deionized water in step S21 is 1g:80-100 mL; the mass ratio of the clove essential oil to the gelatin is 3: 1; the mass ratio of the wormwood essential oil to the gum arabic is 3: 1; the volume ratio of the mixed solution e, the glutaraldehyde and the tannic acid solution with the mass fraction of 16-20% in the step S23 is 20: 1: 4.

7. the processing method of the mould-proof traditional Chinese medicine beverage packaging bag according to claim 1, characterized by comprising the following steps:

Technical Field

The invention belongs to the technical field of medicine packaging, and particularly relates to a mildew-proof traditional Chinese medicine beverage packaging bag and a processing method thereof.

Background

At present, the traditional Chinese medicine is generally taken by patients by adopting traditional Chinese medicine hospitals to prepare various traditional Chinese medicines for the patients, and the patients can not achieve the medical effect due to various reasons by decocting according to the advice of doctors. Some medical units can be filled with the traditional Chinese medicine by using plastic bottles after decocting the traditional Chinese medicine, and the traditional Chinese medicine is convenient to carry but not easy to store.

The invention discloses a patent CN107385991A, which mainly relates to the technical field of packaging paper processing and discloses antibacterial and mildewproof packaging paper, which is prepared from the following raw materials: corn straw, wheat straw, scandent hop, mulberry leaf, madder, Chinese mosla herb, volcanic rock, activated carbon, chitosan, dipotassium glycyrrhizinate, sodium selenite and lipase; the raw materials are easy to obtain, the preparation is simple, the price is low, the antibacterial rate can reach 88%, the antibacterial property is strong, the antibacterial agent is safe and nontoxic to human bodies, and the health of human bodies can be guaranteed when packaged articles are used; corn stalk and wheat straw are extensive in source, and low price makes the wrapping paper quality light, easily transports and uses, and corn stalk and wheat straw's crushing particle diameter is great, increases fiber length, and the interfibrous connection of being convenient for improves wrapping paper intensity, avoids the wrapping paper to fall hair, and the lipase of adding not only can decompose the fat composition in the raw materials, is convenient for copy paper, can also increase the cross-linking effect between the fibre, increases paper intensity and smoothness, and the packing of being convenient for is used, improves the protect function to article.

Disclosure of Invention

In order to overcome the technical problems, the invention provides a mildew-proof traditional Chinese medicine beverage packaging bag and a processing method thereof.

The technical problems to be solved by the invention are as follows:

the traditional Chinese medicine is generally taken by patients by adopting traditional Chinese medicine hospitals to prepare various traditional Chinese medicines, and the patients can take the traditional Chinese medicine by decoction according to the advice of doctors, and the medical effect can not be achieved due to various reasons. Some medical units can be filled with the traditional Chinese medicine by using plastic bottles after decocting the traditional Chinese medicine, and the traditional Chinese medicine is convenient to carry but not easy to store.

The purpose of the invention can be realized by the following technical scheme:

a mildew-proof traditional Chinese medicine beverage packaging bag comprises the following raw materials in parts by weight:

100-200 parts of polymer matrix, 5-10 parts of maleic anhydride grafted polyethylene and 10-12 parts of mildew preventive;

the mildew-proof traditional Chinese medicine beverage packaging bag is processed by the following steps:

Further, the head temperature of the double-screw extruder is 150-170 ℃, and the die temperature is 160-170 ℃.

Further, the polymer matrix is prepared by the following steps:

Step S12, mixing the mass ratio of 1: 100, uniformly stirring the mixture a and deionized water to obtain a suspension, and mixing the span 80 and the polyglycerol fatty acid ester according to the mass ratio of 1; 1, adding the mixture into a three-neck flask, stirring for 6-10min under the conditions that the temperature is 40-60 ℃ and the rotating speed is 300-400r/min, then adding the suspension into the three-neck flask, keeping the temperature and the rotating speed unchanged, continuously stirring for 26-30min to obtain an emulsion, and drying the obtained emulsion for 3-5d at 50 ℃ to obtain a mixture b; the pyrolysis temperature of the mixture a is improved after the surface of the mixture a is treated by the span 80, the span 80 contains a plurality of C-H bonds, the span 80 can coat the mixture a in the reaction process, the dispersibility of the mixture a is improved, the polyglycerol fatty acid ester has an amphiphilic molecular structure, after the polyglycerol fatty acid ester is uniformly dispersed, the hydrophilic groups are outward, the hydrophobic groups are inward, when water vapor generated after the traditional Chinese medicine drink is heated is attached to the surface of the packaging bag, the surface of the packaging bag is hydrophilic, the surface tension of the packaging bag is reduced, and the formation of water mist is prevented.

Step S13, adding the mixture b into dimethylbenzene, stirring for 18-24min at the temperature of 80 ℃ and the rotation speed of 200-300r/min, then adding linear low-density polyethylene, raising the temperature to 140 ℃ and keeping the rotation speed unchanged, continuing stirring for 20-30min, then placing the reaction liquid in a ventilation cabinet for 10-12h to obtain a mixture, washing the mixture for three times by using an ethanol water solution with the volume fraction of 95%, and after washing is finished, drying in vacuum at 80 ℃ to constant weight to obtain a polymer matrix. After the mixture b is dissolved in toluene, the mixture b treated by the surfactant and linear low-density polyethylene can be better crosslinked, the pyrolysis temperature of the prepared polymer matrix is increased, the mixture b is left open and stands overnight, the solvent toluene can be removed, and the ethanol solution with the volume fraction of 95 can remove the redundant surfactant span 80.

Further, in step S11, the vinyltriethoxysilane accounts for 3-5% by mass of the microfibrillated cellulose, and the ratio of the amount of the microfibrillated cellulose to the 95% by volume of the ethanol aqueous solution is 1g: 10-15 mL; the mass ratio of the mixture a to the span 80 in the step S12 is 10: 1; the using ratio of the mixture b, the xylene and the linear low density polyethylene in the step S13 is 8-10 g:100mL of: 85 g.

Further, the mildewcide is prepared by the following steps:

step S21, mixing the mass ratio of 1: adding gelatin and Arabic gum of 1 into deionized water, stirring at 40-60 deg.C until completely dissolving to obtain gelatin solution and Arabic gum solution, dripping clove essential oil into the gelatin solution, stirring at 50-60 deg.C and 3900-; the essential oil is dispersed into small oil drops under the high-speed shearing force, and then the small oil drops are coated on the surfaces of the oil drops under the emulsification action of gelatin and Arabic gum;

step S23, adding glutaraldehyde into the mixed solution e at the temperature of 2-4 ℃, stirring for 20-40min at the rotation speed of 600r/min for 500 plus materials, then raising the temperature to 35-45 ℃, keeping the rotation speed unchanged, continuing to stir for 2h, then adding tannic acid solution with the mass fraction of 16-20%, keeping the temperature and the rotation speed unchanged, continuing to stir for 3h, centrifuging for 9-11min to remove supernatant after stirring is finished at the condition of 5000r/min, washing the obtained solid with deionized water for 3-5 times, and carrying out vacuum freeze drying on the washed solid at the temperature of-70 ℃ to obtain the mildew preventive. When glutaraldehyde is cured independently, powder particles cannot be obtained and are easy to form blocks, the mildew inhibitor obtained by composite curing of glutaraldehyde and tannic acid is powdery, essential oil cannot be released in the low-temperature drying process, the essential oil is slowly released in the use process of the traditional Chinese medicine beverage packaging bag, and the durability of antibiosis and mildew resistance is improved.

Further, the dosage ratio of the gelatin, the gum arabic and the deionized water in the step S21 is 1g:80-100 mL; the mass ratio of the clove essential oil to the gelatin is 3: 1; the mass ratio of the wormwood essential oil to the gum arabic is 3: 1; the volume ratio of the mixed solution e, the glutaraldehyde and the tannic acid solution with the mass fraction of 16-20% in the step S23 is 20: 1: 4.

further, a processing method of the mildew-proof traditional Chinese medicine beverage packaging bag comprises the following steps:

The invention has the beneficial effects that:

the antibacterial property is enhanced along with the increase of the mildew preventive, but the overall quality of the packaging bag is affected when the mildew preventive is increased, the surface of cellulose molecules contains a plurality of hydroxyl groups, hydrogen bonds are easily formed in the process of compounding the cellulose molecules with a thermoplastic polymer matrix to cause agglomeration, the enhancement effect is not added, in addition, the cellulose is polar molecules, the polymer matrix is generally non-polar molecules, the compatibility of the cellulose and the polymer matrix is poor, the application of the cellulose in the enhanced polyolefin composite material is limited, the vinyltriethoxysilane and the microfibrillated cellulose are combined together, the phenomenon of the microfibrillated cellulose in the synthesized polymer matrix is reduced, the pyrolysis temperature of the surface of the mixture a is improved after the agglomeration of the mixture a is treated by the span 80, the span 80 contains a plurality of C-H bonds, the span 80 can coat the mixture a in the reaction process, and the dispersibility of the mixture a is improved, after the mixture b is dissolved in toluene, the mixture b treated by the surfactant and linear low-density polyethylene can be better crosslinked, the pyrolysis temperature of the prepared polymer matrix is increased, the mixture b is left open and stands overnight, the solvent toluene can be removed, and the ethanol with the volume fraction of 95 can remove the redundant surfactant span 80. The linear low-density polyethylene can generate unsaturated double bonds in the melt extrusion process, at the moment, the unsaturated double bonds react with vinyl in the vinyl triethoxysilane, and the combination of the microfibrillated cellulose and the linear low-density polyethylene is realized through the bidirectional reaction of the coupling agent, the microfibrillated cellulose and the linear low-density polyethylene, and the mechanical property of the packaging bag is improved.

The clove essential oil extracted from clove has excellent antibacterial and antioxidant capabilities, the wormwood essential oil is extracted from stems and leaves of wormwood and has antibacterial and antiviral effects, the essential oil is dispersed into small oil drops under high-speed shearing force and then coated on the surfaces of the oil drops under the emulsification effect of gelatin and gum arabic; after the emulsion c and the emulsion d are mixed, the gum arabic is polyelectrolyte and has charges, so that oil droplets have the same charges, and electrostatic repulsion occurs, so that the oil droplets can exist stably; when glutaraldehyde is cured independently, powder particles cannot be obtained and are easy to form blocks, the mildew inhibitor obtained by composite curing of glutaraldehyde and tannic acid is powdery, essential oil cannot be released in the low-temperature drying process, the essential oil is slowly released in the use process of the traditional Chinese medicine beverage packaging bag, and the durability of antibiosis and mildew resistance is improved.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A mildew-proof traditional Chinese medicine beverage packaging bag comprises the following raw materials in parts by weight: 100 parts of polymer matrix, 5 parts of maleic anhydride grafted polyethylene and 10 parts of mildew preventive;

the mildew-proof traditional Chinese medicine beverage packaging bag is processed by the following steps:

step one, uniformly stirring a polymer matrix and maleic anhydride grafted polyethylene, blending by a double-screw extruder, carrying out melt extrusion, and then cutting into particles by a granulator, wherein the heating temperature of a first zone to an eighth zone of the double-screw extruder is that the temperature of a first zone of the double-screw extruder is 110 ℃, the temperature of a second zone is 130 ℃, the temperature of a third zone is 140 ℃, the temperature of a fourth zone is 150 ℃, the temperature of a fifth zone is 160 ℃, the temperature of a sixth zone is 170 ℃, the temperature of a seventh zone is 160 ℃ and the temperature of an eighth zone is 150 ℃; the rotating speed of the screw is 30 r/min;

step two, uniformly mixing the particles prepared in the step one with a mildew preventive, connecting the mixture with a casting machine through a single-screw extruder, carrying out melt extrusion to obtain a packaging bag film, and then slitting and making bags to obtain the mildew-proof traditional Chinese medicine beverage packaging bag; the temperatures of all sections of the single-screw extruder are respectively 165 ℃ in the feeding section, 170 ℃ in the melting section, 160 ℃ in the metering section, 40r/min in rotation speed and 3r/min in the rolling speed of the casting machine.

Wherein the head temperature of the double-screw extruder is 150 ℃, and the neck mold temperature is 160 ℃.

Wherein the polymer matrix is prepared by the following steps:

step S11, adjusting the pH value of 95% ethanol water solution by using glacial acetic acid to 2, then adding vinyltriethoxysilane and microfibrillated cellulose, reacting for 2 hours at the temperature of 55 ℃, performing vacuum filtration after the reaction is finished, washing the obtained filter residue with deionized water for three times, and freeze-drying the washed filter residue for 10 hours at the low temperature of-70 ℃ to obtain a mixture a;

step S12, mixing the mass ratio of 1: 100, uniformly stirring the mixture a and deionized water to obtain a suspension, and mixing the span 80 and the polyglycerol fatty acid ester according to the mass ratio of 1; 1, adding the mixture into a three-neck flask, stirring for 6min at the temperature of 40 ℃ and the rotating speed of 300r/min, adding the suspension into the three-neck flask, keeping the temperature and the rotating speed unchanged, continuously stirring for 26min to obtain emulsion, and drying the obtained emulsion at the temperature of 50 ℃ for 3d to obtain a mixture b;

and step S13, adding the mixture b into dimethylbenzene, stirring for 18min at the temperature of 80 ℃ and the rotation speed of 200r/min, then adding linear low-density polyethylene, raising the temperature to 130 ℃, keeping the rotation speed unchanged, continuing stirring for 20min, then placing the reaction solution in a fume hood for 10h in an open manner to obtain a mixture, washing the mixture for three times by using an ethanol water solution with the volume fraction of 95%, and after washing is finished, drying in vacuum at the temperature of 80 ℃ to constant weight to obtain a polymer matrix.

Wherein, in the step S11, the vinyltriethoxysilane accounts for 3% of the weight of the microfibrillated cellulose, and the dosage ratio of the microfibrillated cellulose to the 95% ethanol aqueous solution by volume fraction is 1g:10 mL; the mass ratio of the mixture a to the span 80 in the step S12 is 10: 1; the amount ratio of the mixture b, xylene and linear low density polyethylene in step S13 was 8 g:100mL of: 85 g.

The mildew preventive is prepared by the following steps:

step S21, mixing the mass ratio of 1: adding gelatin and gum arabic of 1 into deionized water, stirring at 40 deg.C until completely dissolved to obtain gelatin solution and gum arabic solution, dripping clove essential oil into the gelatin solution, stirring at 50 deg.C and 3900r/min for 3min to obtain emulsion c, dripping folium Artemisiae Argyi essential oil into the gum arabic solution, stirring at 40 deg.C and 3900r/min for 5min to obtain emulsion d;

step S22, mixing the emulsion c and the emulsion d obtained in the step S21 according to the mass ratio of 1: 1, mixing, stirring for 5min at the temperature of 40 ℃ and the rotation speed of 4000r/min, then adjusting the pH value of a reaction solution to 3 by using an acetic acid solution, continuing stirring for 30min, stopping heating, naturally cooling to room temperature, then reducing the temperature of the reaction solution to 2 ℃ by using ice water, keeping the temperature unchanged, continuing stirring for 50min at the rotation speed of 2000r/min, adjusting the pH value to 8 by using a sodium hydroxide solution with the mass fraction of 40% in the stirring process, and obtaining a mixed solution e after the stirring is finished;

step S23, adding glutaraldehyde into the mixed solution e at the temperature of 2 ℃, stirring for 20min at the rotating speed of 500r/min, then raising the temperature to 35 ℃, keeping the rotating speed unchanged, continuing to stir for 2h, then adding a tannic acid solution with the mass fraction of 16%, keeping the temperature and the rotating speed unchanged, continuing to stir for 3h, centrifuging for 9min to remove supernatant after stirring is finished at the speed of 5000r/min, washing the obtained solid with deionized water for 3 times, and performing vacuum freeze drying on the washed solid at the temperature of-70 ℃ to obtain the mildew preventive.

Wherein the dosage ratio of the gelatin, the gum arabic and the deionized water in the step S21 is 1g:80 mL; the mass ratio of the clove essential oil to the gelatin is 3: 1; the mass ratio of the wormwood essential oil to the gum arabic is 3: 1; the volume ratio of the mixed solution e, the glutaraldehyde and the tannic acid solution with the mass fraction of 16% in the step S23 is 20: 1: 4.

example 2

A mildew-proof traditional Chinese medicine beverage packaging bag comprises the following raw materials in parts by weight: 150 parts of polymer matrix, 8 parts of maleic anhydride grafted polyethylene and 11 parts of mildew preventive;

the mildew-proof traditional Chinese medicine beverage packaging bag is processed by the following steps:

step one, uniformly stirring a polymer matrix and maleic anhydride grafted polyethylene, blending by a double-screw extruder, carrying out melt extrusion, and then cutting into particles by a granulator, wherein the heating temperature of a first zone to an eighth zone of the double-screw extruder is 115 ℃ at a first zone temperature, 140 ℃ at a second zone temperature, 150 ℃ at a third zone temperature, 160 ℃ at a fourth zone temperature, 170 ℃ at a fifth zone temperature, 185 ℃ at a sixth zone temperature, 165 ℃ at a seventh zone temperature and 160 ℃ at an eighth zone temperature; the rotating speed of the screw is 35 r/min;

step two, uniformly mixing the particles prepared in the step one with a mildew preventive, connecting the mixture with a casting machine through a single-screw extruder, carrying out melt extrusion to obtain a packaging bag film, and then slitting and making bags to obtain the mildew-proof traditional Chinese medicine beverage packaging bag; the temperatures of all sections of the single-screw extruder are respectively 165 ℃ in the feeding section, 175 ℃ in the melting section, 165 ℃ in the metering section, 45r/min in rotation speed and 3r/min in the rolling speed of the casting machine.

Wherein the head temperature of the double-screw extruder is 160 ℃, and the neck mold temperature is 165 ℃.

Wherein the polymer matrix is prepared by the following steps:

step S11, adjusting the pH value of 95% ethanol water solution by using glacial acetic acid to 3, then adding vinyltriethoxysilane and microfibrillated cellulose, reacting at the temperature of 60 ℃ for 2.5h, performing vacuum filtration after the reaction is finished, washing the obtained filter residue with deionized water for three times, and freeze-drying the washed filter residue at the low temperature of-70 ℃ for 13h to obtain a mixture a;

step S12, mixing the mass ratio of 1: 100, uniformly stirring the mixture a and deionized water to obtain a suspension, and mixing the span 80 and the polyglycerol fatty acid ester according to the mass ratio of 1; 1, adding the mixture into a three-neck flask, stirring for 8min under the conditions that the temperature is 50 ℃ and the rotating speed is 350r/min, then adding the suspension into the three-neck flask, keeping the temperature and the rotating speed unchanged, continuing stirring for 28min to obtain an emulsion, and drying the obtained emulsion at 50 ℃ for 4d to obtain a mixture b;

and step S13, adding the mixture b into dimethylbenzene, stirring for 20min at the temperature of 80 ℃ and the rotating speed of 250r/min, then adding linear low-density polyethylene, raising the temperature to 135 ℃, keeping the rotating speed unchanged, continuing stirring for 25min, then placing the reaction solution in a fume hood in an open manner for 11h to obtain a mixture, washing the mixture for three times by using an ethanol water solution with the volume fraction of 95%, and after washing is finished, drying in vacuum at the temperature of 80 ℃ to constant weight to obtain a polymer matrix.

Wherein, in the step S11, the vinyltriethoxysilane accounts for 4% of the weight of the microfibrillated cellulose, and the dosage ratio of the microfibrillated cellulose to the 95% ethanol aqueous solution by volume fraction is 1g: 12 mL; the mass ratio of the mixture a to the span 80 in the step S12 is 10: 1; the amount ratio of the mixture b, xylene and linear low density polyethylene in step S13 was 9 g:100mL of: 85 g.

The mildew preventive is prepared by the following steps:

step S21, mixing the mass ratio of 1: adding gelatin and gum arabic of 1 into deionized water, stirring at 50 deg.C until completely dissolved to obtain gelatin solution and gum arabic solution, dripping clove essential oil into the gelatin solution, stirring at 55 deg.C and 4000r/min for 4min to obtain emulsion c, dripping folium Artemisiae Argyi essential oil into the gum arabic solution, stirring at 45 deg.C and 4000r/min for 6min to obtain emulsion d;

step S22, mixing the emulsion c and the emulsion d obtained in the step S21 according to the mass ratio of 1: 1, mixing, stirring for 6min under the conditions that the temperature is 45 ℃ and the rotating speed is 4000r/min, then adjusting the pH value of a reaction solution to 3 by using an acetic acid solution, continuing stirring for 30min, stopping heating, naturally cooling to room temperature, then reducing the temperature of the reaction solution to 3 ℃ by using ice water, keeping the temperature unchanged, continuing stirring for 55min at the rotating speed of 2500r/min, adjusting the pH value to 9 by using a sodium hydroxide solution with the mass fraction of 40% in the stirring process, and obtaining a mixed solution e after the stirring is finished;

and S23, adding glutaraldehyde into the mixed solution e at the temperature of 3 ℃, stirring for 30min at the rotating speed of 550r/min, then increasing the temperature to 40 ℃, keeping the rotating speed unchanged, continuing to stir for 2h, then adding a tannic acid solution with the mass fraction of 18%, keeping the temperature and the rotating speed unchanged, continuing to stir for 3h, centrifuging for 10min at the speed of 5000r/min after stirring is finished to remove a supernatant, washing the obtained solid with deionized water for 4 times, and performing vacuum freeze drying on the washed solid at the temperature of-70 ℃ to obtain the mildew preventive.

Wherein the dosage ratio of the gelatin, the gum arabic and the deionized water in the step S21 is 1g:90 mL; the mass ratio of the clove essential oil to the gelatin is 3: 1; the mass ratio of the wormwood essential oil to the gum arabic is 3: 1; the volume ratio of the mixed solution e, the glutaraldehyde and the tannic acid solution with the mass fraction of 18% in the step S23 is 20: 1: 4.

example 3

A mildew-proof traditional Chinese medicine beverage packaging bag comprises the following raw materials in parts by weight: 200 parts of polymer matrix, 10 parts of maleic anhydride grafted polyethylene and 12 parts of mildew preventive;

the mildew-proof traditional Chinese medicine beverage packaging bag is processed by the following steps:

step one, uniformly stirring a polymer matrix and maleic anhydride grafted polyethylene, blending by a double-screw extruder, carrying out melt extrusion, and then cutting into particles by a granulator, wherein the heating temperature of a first zone to an eighth zone of the double-screw extruder is that the first zone temperature of the double-screw extruder is 120 ℃, the second zone temperature is 150 ℃, the third zone temperature is 160 ℃, the fourth zone temperature is 170 ℃, the fifth zone temperature is 180 ℃, the sixth zone temperature is 200 ℃, the seventh zone temperature is 170 ℃ and the eighth zone temperature is 170 ℃; the rotating speed of the screw is 40 r/min;

step two, uniformly mixing the particles prepared in the step one with a mildew preventive, connecting the mixture with a casting machine through a single-screw extruder, carrying out melt extrusion to obtain a packaging bag film, and then slitting and making bags to obtain the mildew-proof traditional Chinese medicine beverage packaging bag; the temperatures of all sections of the single-screw extruder are respectively 170 ℃ in the feeding section, 180 ℃ in the melting section, 170 ℃ in the metering section, 50r/min in rotation speed and 4r/min in the rolling speed of the casting machine.

Wherein the head temperature of the double-screw extruder is 170 ℃, and the neck mold temperature is 170 ℃.

Wherein the polymer matrix is prepared by the following steps:

step S11, adjusting the pH value of 95% ethanol water solution by using glacial acetic acid to 4, then adding vinyltriethoxysilane and microfibrillated cellulose, reacting for 3 hours at the temperature of 65 ℃, performing vacuum filtration after the reaction is finished, washing the obtained filter residue with deionized water for three times, and freeze-drying the washed filter residue for 16 hours at the temperature of-70 ℃ to obtain a mixture a;

step S12, mixing the mass ratio of 1: 100, uniformly stirring the mixture a and deionized water to obtain a suspension, and mixing the span 80 and the polyglycerol fatty acid ester according to the mass ratio of 1; 1, adding the mixture into a three-neck flask, stirring for 10min at the temperature of 60 ℃ and the rotating speed of 400r/min, adding the suspension into the three-neck flask, keeping the temperature and the rotating speed unchanged, continuously stirring for 30min to obtain emulsion, and drying the obtained emulsion at the temperature of 50 ℃ for 5d to obtain a mixture b;

and step S13, adding the mixture b into dimethylbenzene, stirring for 24min at the temperature of 80 ℃ and the rotating speed of 300r/min, then adding linear low-density polyethylene, raising the temperature to 140 ℃, keeping the rotating speed unchanged, continuing stirring for 30min, then placing the reaction solution in a fume hood in an open manner for 12h to obtain a mixture, washing the mixture for three times by using an ethanol water solution with the volume fraction of 95%, and after washing is finished, drying in vacuum at the temperature of 80 ℃ to constant weight to obtain a polymer matrix.

Wherein, in the step S11, the vinyltriethoxysilane accounts for 5% of the weight of the microfibrillated cellulose, and the dosage ratio of the microfibrillated cellulose to the 95% ethanol aqueous solution by volume fraction is 1g: 15 mL; the mass ratio of the mixture a to the span 80 in the step S12 is 10: 1; the amount ratio of the mixture b, xylene and linear low density polyethylene in step S13 was 10 g:100mL of: 85 g.

The mildew preventive is prepared by the following steps:

step S21, mixing the mass ratio of 1: adding gelatin and Arabic gum of 1 into deionized water, stirring at 60 deg.C until completely dissolved to obtain gelatin solution and Arabic gum solution, adding oleum Caryophylli dropwise into the gelatin solution, stirring at 60 deg.C and 4100r/min for 5min to obtain emulsion c, adding oleum Artemisiae Argyi dropwise into the Arabic gum solution, stirring at 50 deg.C and 4100r/min for 7min to obtain emulsion d;

step S22, mixing the emulsion c and the emulsion d obtained in the step S21 according to the mass ratio of 1: 1, mixing, stirring for 7min at the temperature of 50 ℃ and the rotation speed of 4000r/min, then adjusting the pH value of a reaction solution to 4 by using an acetic acid solution, continuing stirring for 30min, stopping heating, naturally cooling to room temperature, then reducing the temperature of the reaction solution to 4 ℃ by using ice water, keeping the temperature unchanged, continuing stirring for 60min at the rotation speed of 3000r/min, adjusting the pH value to 10 by using a sodium hydroxide solution with the mass fraction of 40% in the stirring process, and obtaining a mixed solution e after the stirring is finished;

and S23, adding glutaraldehyde into the mixed solution e at the temperature of 4 ℃, stirring for 40min at the rotating speed of 600r/min, then increasing the temperature to 45 ℃, keeping the rotating speed unchanged, continuing stirring for 2h, then adding a tannic acid solution with the mass fraction of 20%, keeping the temperature and the rotating speed unchanged, continuing stirring for 3h, centrifuging for 11min to remove supernatant after stirring is finished at the speed of 5000r/min, washing the obtained solid for 5 times with deionized water, and performing vacuum freeze drying on the washed solid at the temperature of-70 ℃ to obtain the mildew preventive.

Wherein the dosage ratio of the gelatin, the gum arabic and the deionized water in the step S21 is 1g:100 mL; the mass ratio of the clove essential oil to the gelatin is 3: 1; the mass ratio of the wormwood essential oil to the gum arabic is 3: 1; the volume ratio of the mixed solution e, the glutaraldehyde and the 20% by mass tannic acid solution in the step S23 is 20: 1: 4.

comparative example 1

The fungicide of example 1 was not added, and the rest of the preparation process and the raw materials were kept unchanged.

Tests the mildew-proof and antibacterial performance and the acute toxicity of the mildew inhibitor,

acute oral toxicity test:

80 white mice are randomly divided into 4 groups, each group comprises 20 mice, each half of the mice is male and female, and three groups of the white mice are experimental groups; the mildewcide prepared in examples 1 to 3 and the physiological saline 1: 10 mixing, and after mixing, orally gavage the mixture to test white rats, wherein the mixture is administered once every 4h, and after four times, 7d is observed to see whether any toxic symptom exists; control group a group of white mice: the normal saline was orally administered to the test group of white mice by gavage, and the mice were observed in the same time as the test group.

Test results of acute oral toxicity test: none of the rats died in both the experimental and control groups.

And (3) testing the mildew-proof antibacterial performance:

first, 1X 10 of⁶±2×10⁵Spore suspension of spore count/mL, then the packaging film prepared in examples 1-3 and comparative example 1 was laid flat on the culture medium, and an equal amount of spore suspension was sprayed so as to be sufficiently and uniformly sprayed on the surface of the culture medium and the packaging film prepared in examples 1-3 and comparative example 1, at a temperature ofCulturing the Chinese medicinal drink packaging bags at the temperature of 28 ℃ and the relative humidity of more than 90% for 30 days, wherein the test results are shown in the following table, and performing mechanical property test on the mildew-proof Chinese medicinal drink packaging bags prepared in the examples 1-3 and the comparative example 1, wherein the test results are shown in the following table 1;

TABLE 1

Detecting items	Example 1	Example 2	Example 3	Comparative example 1
					Coli reduction (%)	99.45	99.51	99.11	77.8
Reduction of Staphylococcus aureus (%)	99.88	99.12	99.23	81.2
					Growth of mold	Not long	Not long	Not long	The area of the long mold is less than 10 percent
Tensile strength N/10mm	28.1	27.2	27.5	27.8
					Elongation at break/%	243	251	248	241

From the above table 1, it can be seen that the mechanical properties of the mildew-proof traditional Chinese medicine beverage packaging bag prepared by the invention are maintained on the premise of ensuring the antibacterial and mildew-proof properties.

The foregoing is illustrative and explanatory only and is not intended to be exhaustive or to limit the invention to the precise embodiments described, and various modifications, additions, and substitutions may be made by those skilled in the art without departing from the scope of the invention or exceeding the scope of the claims.

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Mildew-proof traditional Chinese medicine beverage packaging bag and processing method thereof

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