阅读说明：本技术 一种可调节植入深度的发射器 (Emitter capable of adjusting implantation depth ) 是由 丁建林 杨清刚 陈玮 于 2020-05-22 设计创作，主要内容包括：本发明提供一种可调节植入深度的发射器,包括探针、深度调节装置与调节锁片,探针与深度调节装置连接,深度调节装置包括定位组件与滑动组件,定位组件与滑动组件相互配合,能够调节探针伸出长度；调节锁片被配置为能够锁定定位组件,使探针伸出长度保持不变。定位组件包括卡筋与凹槽；滑动组件包括滑轨与滑块,滑块能够在滑轨中滑动。本发明中卡筋和凹槽,滑轨和滑块的设置,有利于调节探针伸出底座的长度大小,从而适宜于植入不同厚度皮肤的人体皮下,提高检测结果的准确性。本发明能够适用于多种皮肤厚度的人群。本发明的发射器还能够锁住探针伸出底座的长度,避免其他外力作用改变探针伸出底座的长度。(The invention provides a transmitter capable of adjusting implantation depth, which comprises a probe, a depth adjusting device and an adjusting locking plate, wherein the probe is connected with the depth adjusting device, the depth adjusting device comprises a positioning component and a sliding component, and the positioning component and the sliding component are matched with each other and can adjust the extending length of the probe; the adjustment locking piece is configured to lock the positioning component, so that the extending length of the probe is kept constant. The positioning component comprises a clamping rib and a groove; the sliding assembly comprises a sliding rail and a sliding block, and the sliding block can slide in the sliding rail. The arrangement of the clamping ribs, the grooves, the sliding rails and the sliding blocks is favorable for adjusting the length of the probe extending out of the base, so that the probe is suitable for being implanted into the subcutaneous parts of the human body with skin of different thicknesses, and the accuracy of a detection result is improved. The invention can be suitable for people with various skin thicknesses. The emitter of the invention can also lock the length of the probe extending out of the base, thereby avoiding the change of the length of the probe extending out of the base under the action of other external forces.)

1. The emitter capable of adjusting the implantation depth is characterized by comprising a probe, a depth adjusting device and an adjusting locking plate, wherein the probe is connected with the depth adjusting device, the depth adjusting device comprises a positioning assembly and a sliding assembly, and the positioning assembly is matched with the sliding assembly to adjust the extending length of the probe; the adjustment locking piece is configured to lock the positioning component, so that the extending length of the probe is kept constant.

2. The transmitter of claim 1, wherein the positioning assembly comprises a rib and a groove, and the rib can be combined with or separated from the groove.

3. The transmitter of claim 1, wherein the sliding assembly comprises a sliding track and a sliding block, and the sliding block can slide in the sliding track.

4. The transmitter of claim 1, wherein the depth adjusting means comprises a bracket and a base, the bracket being connected to the base.

5. The emitter of claim 4, wherein said bracket has a rib and a rail.

6. The emitter of claim 4, wherein the base has a sliding block and a groove.

7. The adjustable implantation depth transmitter of claim 1, wherein the locking plate is provided with a stop.

8. The emitter of claim 1, wherein the bottom of the adjusting locking plate is provided with a handle.

9. The transmitter of claim 2, wherein the rib has a protrusion.

10. The transmitter capable of adjusting the implantation depth according to claim 1, further comprising an upper cover, a circuit board assembly, a supporting member and a transmission member, wherein the upper cover is provided with an implantation channel and a shift position.

Technical Field

The invention relates to the field of continuous monitoring of blood sugar, in particular to a transmitter capable of adjusting implantation depth.

Background

The subcutaneous implanted continuous blood glucose monitoring system (CGMS) can be used as a beneficial supplement or even a substitute for the traditional blood glucose monitoring product, provides the map information of blood glucose change and reduces or avoids pain caused by finger blood collection of a patient. CGMS is a monitoring technology that reflects the blood glucose level by monitoring the glucose concentration in the interstitial fluid of the subcutaneous tissue using a glucose sensor, can provide continuous and comprehensive blood glucose information, can visually compare it with a "blood glucose electrogram", is similar to an electrocardiogram, can obtain a blood glucose fluctuation map of a patient during wearing, and is a tool for understanding the relationship between factors such as food type, exercise type, drug variety, mental factor, lifestyle and the like and blood glucose fluctuation of the patient, helping to formulate an individualized treatment scheme, improving treatment compliance, and performing visual diabetes education.

CGMS generally consists of a GOx-based "needle-type" electrochemical glucose sensor that can be implanted subcutaneously in a human body with minimal trauma, a set of wireless or wired signal detection and transmission/recording devices (transmitters), and an algorithm (usually placed in an App or receiver) that converts the detected current signal into glucose concentration, often with the need for a needle assist device to implant the sensor subcutaneously. The sensor (i.e. the probe) is penetrated into the subcutaneous part by the needle assisting device, the sensor forms an electric signal when the sensor is oxidized and reacts with glucose in the body in the tissue fluid of a patient, and the electric signal is converted into a blood glucose reading and then transmitted to the receiver by the transmitter. Under the guidance of the data and the visual chart, a clinician can comprehensively understand the 24-hour blood sugar fluctuation condition of the patient, and can be matched with an insulin pump to inject insulin to the patient when necessary.

Generally, CGM sensor working electrodes consist of a surface metal layer, an inner layer, an enzyme layer, and an outer membrane. Dissolved oxygen and glucose in Interstitial Fluid (ISF) enter an enzyme layer through an outer membrane, glucose molecules react with the enzyme to generate electroactive reaction products, namely hydrogen peroxide and gluconic acid, the hydrogen peroxide diffuses inwards and outwards respectively, the inwards diffused part reaches the surface of an electrode, electrode reaction is carried out, and electrode current is formed. The current and the glucose concentration have an approximate linear relationship within a certain range, so that the glucose concentration can be converted by the magnitude of the current value.

At present, except that a Dexcom company uses a flexible noble metal alloy wire as a sensor substrate material, other companies basically adopt a flexible substrate material PI or PET, then metallization and patterning are carried out on the flexible substrate material PI or PET to realize preparation of an electrode, a sensor probe is sleeved in a semi-closed needle before implantation, the semi-closed needle wraps the sensor probe and enters the subcutaneous space under the action of a needle booster, the needle booster is taken down, the semi-closed needle is also taken off, and the sensor probe is smoothly implanted into the subcutaneous space.

CGMS can correctly reflect the change of blood sugar of human body, which is based on the assumption that the concentration of glucose in intercellular fluid is very similar to the concentration of blood sugar, and is basically based on the fact that the glucose in tissue fluid derived from capillary vessels of human body has higher correlation with blood sugar, and the current generated by biochemical reaction of glucose in tissue fluid can be converted into blood sugar detection value by referring to the calibration of blood sugar value. This requires that the sensor be closer to the site of capillary abundance, with greater accuracy. Since the CGM sensor is usually required to be implanted into the subcutaneous fat layer, different individuals have different body conditions, different thicknesses of the fat layer and different degrees of abundance of capillary vessels, and different implantation depth adjustment mechanisms are helpful for obtaining the maximum effective area of the sensor and ensuring the sensitivity of the sensor. Human fat generally has both a white and brown color, of which: white fat accumulates under the skin, responsible for storing excess energy, and also forms unsightly fat proud; the brown fat cell contains a large amount of mitochondria and is rich in capillary vessels, so that a brown fat part or a joint of white fat and brown fat is a recommended implantation part of the CGM sensor.

The implantation depth of the sensor in the continuous blood sugar monitoring products which are released in the market at present is not adjustable, so that when a patient with too thick or too thin skin uses the continuous blood sugar monitoring products, the probe of the sensor cannot reach a proper monitoring position, and the accuracy of a test result is influenced.

Disclosure of Invention

The technical problem to be solved by the present invention is to provide a transmitter capable of adjusting the implantation depth, aiming at the problems in the background art.

Therefore, the technical scheme adopted by the invention is as follows:

a transmitter capable of adjusting implantation depth comprises a probe, a depth adjusting device and an adjusting locking plate, wherein the probe is connected with the depth adjusting device, the depth adjusting device comprises a positioning assembly and a sliding assembly, and the positioning assembly is matched with the sliding assembly to adjust the extending length of the probe; the adjustment locking piece is configured to lock the positioning component, so that the extending length of the probe is kept constant.

Further, the locating component comprises a clamping rib and a groove, and the clamping rib can be combined with or separated from the groove.

Further, the sliding assembly comprises a sliding rail and a sliding block, and the sliding block can slide in the sliding rail.

Further, the depth adjusting device comprises a bracket and a base, and the bracket is connected with the base.

Furthermore, the bracket is provided with a clamping rib and a sliding rail.

Furthermore, a sliding block and a groove are arranged on the base.

Furthermore, a blocking piece is arranged on the adjusting locking piece.

Further, a handle is arranged at the bottom of the adjusting locking plate.

Further, the clamping rib is provided with a convex part.

Furthermore, the transmitter also comprises an upper cover, a circuit board assembly, a supporting piece and a transmission component, wherein the upper cover is provided with an implantation channel and a gear.

The invention has the beneficial effects that:

(1) the emitter capable of adjusting the implantation depth is provided with the positioning component (the clamping ribs and the grooves) and the sliding component (the sliding rails and the sliding blocks), and the positioning component and the sliding component are matched with each other, so that the length of the probe extending out of the base can be adjusted, the emitter is suitable for being implanted into the subcutaneous parts of the human body with skins of different thicknesses, and the accuracy of a detection result is improved. The invention can be suitable for people with various skin thicknesses.

(2) In the invention, the clamping ribs are made of elastic materials, so that the clamping ribs can conveniently enter the grooves or be separated from the grooves; the recess is big-end-up's trapezium structure, sets up like this and plays the guide effect, and the card muscle of being convenient for gets into the recess, and the card muscle of being convenient for breaks away from the recess moreover for the card muscle can remove between a plurality of recesses more in a flexible way, conveniently adjusts the length that the probe stretches out the base.

(3) In the invention, the outer side wall of the upper cover is provided with gears, different gears correspond to different lengths of the probe extending out of the base, different gears correspond to gear lines with different lengths, and the length of the gear line represents the length of the probe extending out of the base; therefore, the implantation depth can be adjusted by a user, and the length of the probe extending out of the base can be accurately judged by the user according to the length of the gear line.

(4) The emitter also comprises an adjusting locking plate, when the adjusting locking plate is in a locking state, the clamping ribs can be prevented from jumping among the grooves, so that the bracket and the base cannot rotate relatively, namely, the length of the probe extending out of the base is locked, and the length of the probe extending out of the base is prevented from being changed by other external force.

Drawings

Fig. 1 is an exploded view of the structure of the transmitter of the present invention.

Fig. 2 is a schematic structural view of the upper cover.

Fig. 3 is a schematic structural view of the bracket.

Fig. 4 is a schematic structural diagram of the base.

Fig. 5 is a cross-sectional view of an emitter of the present invention.

Fig. 6 is a schematic diagram of the probe implanted in the skin of a human body after the transmitter of the present invention is adjusted to different gears.

Fig. 7 is a schematic view of the internal structure of the upper cover.

Fig. 8 is a schematic view of the internal structure of the bracket.

Fig. 9 is a schematic structural view of the supporting member.

FIG. 10 is a schematic view of the structure of the probe.

FIG. 11 is a schematic view of the structure of the support member, probe and transport member mounted in the receptacle.

Fig. 12 is a schematic structural view of the emitter of the present invention after the upper cover is opened.

Figure 13 is a schematic view of the support, probe and transport assembly mounted in the receptacle (showing the ramp configuration).

Fig. 14 is a schematic view of the structure of the emitter of the present invention with the semi-closed needle installed in the implantation channel.

Fig. 15 is an exploded view of the structure of the transmitter in example 2.

Fig. 16 is a schematic structural view of the adjusting locking piece in embodiment 2.

Fig. 17 is a schematic structural view of a base in embodiment 2.

Fig. 18 is a bottom perspective view of the transmitter of embodiment 2 with the adjustment locking tab in an unlocked position.

Fig. 19 is a schematic view showing the structure of the transmitter in embodiment 2 when the adjusting lock plate is unlocked (a part of the upper cover is hidden to show the relative position of the locking rib and the adjusting lock plate).

Fig. 20 is a bottom perspective view of the launcher with the locking tab adjusted in the locked position according to embodiment 2.

Fig. 21 is a schematic view showing the structure of the transmitter in embodiment 2 when the adjusting locking piece is in the locked state (a part of the upper cover is hidden to show the relative position relationship between the locking rib and the adjusting locking piece).

Detailed Description

The following detailed description of the embodiments of the present invention is provided in conjunction with the accompanying drawings, and it should be noted that the embodiments are merely illustrative of the present invention and should not be construed as limiting the present invention.