阅读说明：本技术 一种肌少症患者的肠内营养制剂 (Enteral nutrition preparation for sarcopenia patients ) 是由 罗蔓 李希 任卫英 胡予 崔怡婷 刘楚 韦怡超 陈玲燕 姜立经 高键 于 2021-07-14 设计创作，主要内容包括：本发明公开了一种肌少症患者的肠内营养制剂。本发明的肌少症患者的肠内营养制剂包括乳清蛋白、亮氨酸,β-羟基-β-甲基丁酸(β-hydroxy-β-methylbutyrate,HMB),维生素D、其他维生素和微量元素。本发明的配方中以乳清蛋白为主,并辅以亮氨酸及其代谢物HMB作为主要营养素,患者服用后体内吸收消化速度快,餐后促蛋白质合成作用好,可以增加患者肌肉的强度。本发明的肠内营养制剂富含乳清蛋白、亮氨酸、HMB、维生素D,可以改善肌少症患者的肌肉质量和力量,可作为治疗肌少症的专用营养补充剂。(The invention discloses an enteral nutrition preparation for patients with sarcopenia. The enteral nutrition preparation for sarcopenia patients comprises lactalbumin, leucine, beta-hydroxy-beta-methylbutyrate (HMB), vitamin D, other vitamins and trace elements. The formula of the invention takes whey protein as the main ingredient and leucine and metabolite HMB thereof as the main nutrient, so that the absorption and digestion speed in vivo of a patient is high after taking the formula, the protein synthesis promotion effect is good after eating, and the muscle strength of the patient can be increased. The enteral nutrition preparation of the invention is rich in whey protein, leucine, HMB and vitamin D, can improve the muscle quality and strength of patients with sarcopenia, and can be used as a special nutritional supplement for treating sarcopenia.)

1. An enteral nutritional preparation for patients with sarcopenia, wherein the enteral nutritional preparation comprises whey protein, leucine, beta-hydroxy-beta-methylbutyrate HMB, vitamins and trace elements; the vitamin comprises vitamin D.

2. The enteral nutritional formulation for sarcopenia patients according to claim 1, wherein the vitamins further comprise vitamin C, vitamin a, vitamin E, carotenoids, microorganism K1, folic acid, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, pantothenic acid and biotin.

3. An enteral nutritional formulation for patients with sarcopenia as claimed in claim 1 wherein the trace elements comprise sodium, potassium, chloride, calcium, zinc, magnesium, phosphorus, selenium and molybdenum.

4. The enteral nutritional formulation for sarcopenia patients according to claim 1, wherein the ingredients of the enteral nutritional formulation further comprise carbohydrates, fats, dietary fibers and choline.

5. Enteral nutritional formulation for patients with sarcopenia according to claim 1, the enteral nutrition preparation contains 50-60 g of whey protein, 5-6 g of leucine, 5-6 g of beta-hydroxy-beta-methylbutyrate HMB, 15-30 g of carbohydrate, 5-6 g of fat, 2000U of vitamin, 4g of dietary fiber, 420mg of sodium, 650mg of potassium, 520mg of chlorine, 200mg of calcium, 5mg of zinc, 84mg of magnesium, 250mg of phosphorus, 22 μ g of selenium, 39 μ g of molybdenum, 40mg of vitamin C, 420 μ g of RE of vitamin A, 5.2mg of alpha-TE of vitamin E, 0.95mg of carotenoid, 116 μ g of vitamin K, 220 μ g of folic acid, 10.81mg of vitamin B, 20.72mg of vitamin B, 61.1mg of vitamin B, 121 μ g of vitamin B, 11mg of nicotinic acid, 4mg of pantothenic acid, 14 μ g of biotin and 110mg of choline per 100 g.

Technical Field

The invention relates to an enteral nutrition preparation for sarcopenia patients, belonging to the technical field of nutritional supplements.

Background

The nutritional therapy is an important treatment means for the sarcopenia patients, but the conventional oral enteral nutritional preparation formula on the market has low protein content, mainly contains casein, is not suitable for the sarcopenia patients, and has no enteral nutritional preparation specially for the sarcopenia patients at home at present.

Disclosure of Invention

The technical problem solved by the invention is as follows: the conventional oral enteral nutrition preparation formula on the market has low protein content, mainly contains casein, and is not suitable for sarcopenia patients.

In order to solve the above technical problems, the present invention provides an enteral nutritional preparation for sarcopenia patients, the enteral nutritional preparation comprising whey protein, leucine, HMB, β -hydroxy- β -methylbutyrate, vitamins and trace elements; the vitamin comprises vitamin D.

Preferably, the vitamins further comprise vitamin C, vitamin A, vitamin E, carotenoids, microorganism K1, folic acid, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, pantothenic acid, and biotin.

Preferably, the trace elements include sodium, potassium, chloride, calcium, zinc, magnesium, phosphorus, selenium and molybdenum.

Preferably, the enteral nutritional formulation further comprises carbohydrates, fat, dietary fiber and choline.

Preferably, the enteral nutrition preparation contains 50-60 g of whey protein, 5-6 g of leucine, 5-6 g of beta-hydroxy-beta-methylbutyrate HMB, 15-30 g of carbohydrate, 5-6 g of fat, vitamin D2000U, 4g of dietary fiber, 420mg of sodium, 650mg of potassium, 520mg of chlorine, 200mg of calcium, 5mg of zinc, 84mg of magnesium, 250mg of phosphorus, 22 μ g of selenium, 39 μ g of molybdenum, 40mg of vitamin C, 420 μ g of RE of vitamin A, 5.2mg of alpha-TE of vitamin E, 0.95mg of carotenoid, 116 μ g of vitamin K, 220 μ g of folic acid, 10.81mg of vitamin B, 20.72mg of vitamin B, 61.1mg of vitamin B, 121 μ g of vitamin B, 11mg of nicotinic acid, 4mg of pantothenic acid, 14 μ g of biotin and 110mg of choline per 100g of the enteral nutrition preparation.

Compared with the prior art, the invention has the following beneficial effects:

1. the enteral nutrition preparation is rich in whey protein, leucine, HMB and vitamin D, can improve the muscle quality and strength of patients with sarcopenia, and can be used as a special nutritional supplement for treating sarcopenia;

2. the formula of the invention takes whey protein as the main ingredient and leucine and a metabolite HMB thereof as a main nutrient, wherein the leucine can activate a signal path of protein synthesis, the protein synthesis promoting capability of the leucine is 10 times higher than that of other amino acids, and the stability of skeletal muscle mass mainly depends on the dynamic balance of muscle protein synthesis and catabolism, so that the in-situ nutrient preparation of the invention has high leucine content, high in-vivo absorption and digestion speed, good in postprandial protein synthesis promoting effect and capability of increasing the muscle strength of a patient.

Detailed Description

In order to make the invention more comprehensible, preferred embodiments are described in detail below.

Example 1

An enteral nutrition preparation for patients with sarcopenia, comprising the following nutrients per 100g of enteral nutrition preparation: 60 g of lactalbumin, 6 g of leucine, 6 g of HMB (beta-hydroxy-beta-methylbutyrate), 15 g of carbohydrate, 6 g of fat, 2000U of vitamin, 4g of dietary fiber, 420mg of sodium, 650mg of potassium, 520mg of chlorine, 200mg of calcium, 5mg of zinc, 84mg of magnesium, 250mg of phosphorus, 22 μ g of selenium, 39 μ g of molybdenum, 40mg of vitamin C, 420 μ g of RE of vitamin A, 5.2mg of alpha-TE of vitamin E, 0.95mg of carotenoid, 116 μ g of vitamin K, 220 μ g of folic acid, 10.81mg of vitamin B, 20.72mg of vitamin B, 61.1mg of vitamin B, 121 μ g of vitamin B, 11mg of nicotinic acid, 4mg of pantothenic acid, 14 μ g of biotin and 110mg of choline.

Example 2

An enteral nutrition preparation for patients with sarcopenia, comprising the following nutrients per 100g of enteral nutrition preparation: 50 g of whey protein, 5 g of leucine, 5 g of HMB (beta-hydroxy-beta-methylbutyrate), 28 g of carbohydrate, 5 g of fat, 2000U of vitamin, 4g of dietary fiber, 420mg of sodium, 650mg of potassium, 520mg of chlorine, 200mg of calcium, 5mg of zinc, 84mg of magnesium, 250mg of phosphorus, 22 μ g of selenium, 39 μ g of molybdenum, 40mg of vitamin C, 420 μ g of RE of vitamin A, 5.2mg of alpha-TE of vitamin E, 0.95mg of carotenoid, 116 μ g of vitamin K, 220 μ g of folic acid, 10.81mg of vitamin B, 20.72mg of vitamin B, 61.1mg of vitamin B, 121 μ g of vitamin B, 11mg of nicotinic acid, 4mg of pantothenic acid, 14 μ g of biotin and 110mg of choline.

Example 3

An enteral nutrition preparation for patients with sarcopenia, comprising the following nutrients per 100g of enteral nutrition preparation: 54 g of lactalbumin, 5.4 g of leucine, 5.4 g of HMB (beta-hydroxy-beta-methylbutyrate), 22.8 g of carbohydrate, 5.4 g of fat, 2000U of vitamin D, 4g of dietary fiber, 420mg of sodium, 650mg of potassium, 520mg of chlorine, 200mg of calcium, 5mg of zinc, 84mg of magnesium, 250mg of phosphorus, 22 μ g of selenium, 39 μ g of molybdenum, 40mg of vitamin C, 420 μ g of RE of vitamin A, 5.2mg of alpha-TE of vitamin E, 0.95mg of carotenoid, 116 μ g of vitamin K, 220 μ g of folic acid, 10.81mg of vitamin B, 20.72mg of vitamin B, 61.1mg of vitamin B, 121 μ g of vitamin B, 11mg of nicotinic acid, 4mg of pantothenic acid, 14 μ g of biotin and 110mg of choline.

While the invention has been described with respect to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention.