阅读说明：本技术 绞股蓝植物提取物溶液及其在制备促进毛发生长药物中的应用 (Gynostemma pentaphylla plant extract solution and application thereof in preparing medicine for promoting hair growth ) 是由 刘小锦 王本阳 于 2020-06-01 设计创作，主要内容包括：本发明涉及毛发生长药物制备技术领域,尤其涉及绞股蓝植物提取物溶液及其在制备促进毛发生长药物中的应用。本发明选用绞股蓝植物提取物应用于生发研究,具体的可促进人真皮乳头细胞的增殖,可增加毛囊细胞个数,增大毛囊生长长度,增加毛发生长长度,即绞股蓝植物提取物表现出了显著的生发效果。(The invention relates to the technical field of hair growth medicine preparation, in particular to a gynostemma pentaphylla plant extract solution and application thereof in preparing a medicine for promoting hair growth. The gynostemma pentaphylla plant extract is applied to hair growth research, and specifically can promote the proliferation of human dermal papilla cells, increase the number of hair follicle cells, increase the growth length of hair follicles and increase the growth length of hairs, namely the gynostemma pentaphylla plant extract shows a remarkable hair growth effect.)

1. Application of herba Gynostemmatis plant extract solution in preparing medicine for promoting hair growth is provided.

2. The application of claim 1, wherein the application method comprises: the gynostemma pentaphylla plant extract is dissolved in tween 80 to prepare a gynostemma pentaphylla plant extract solution, and the solution can be applied to promoting hair growth.

3. The use of claim 2, wherein the concentration of the gynostemma pentaphyllum plant extract solution is 50mg/ml to 800 mg/ml.

4. Use according to claim 1 or 2, wherein the hair comprises hair.

5. A Gynostemma pentaphyllum extract solution for use in any one of claims 1 to 4.

Technical Field

The invention relates to the technical field of hair growth medicine preparation, in particular to a gynostemma pentaphylla plant extract solution and application thereof in preparing a medicine for promoting hair growth.

Background

The hair of people plays an important role in social interaction, and the alopecia not only affects the personal image, but also has a plurality of obstacles to life and work. Under great demand, scientists at home and abroad have done much work to study the mechanism of alopecia and solutions.

Currently, only two chemically synthesized drugs are approved by the FDA for the treatment of androgenetic alopecia, finasteride orally and minoxidil topically. But the side effects of both drugs are also very significant, finasteride has the potential risk of external genital malformations in the male fetus and is therefore contraindicated in fertility or pregnant women. The effect of minoxidil is temporary and several adverse effects have been reported, such as itching, dermatitis and irritation.

Gynostemma pentaphylla is a plant in the genus of Gynostemma belonging to the family Cucurbitaceae, with thin and weak stem, branch, longitudinal edge and groove, and no hair or short hair. The main effective components of gynostemma pentaphylla include gypenoside, gypenoside (polysaccharide), water soluble amino acid, flavone, vitamins, trace elements, minerals, etc. The product has effects of relieving inflammation, removing toxic substances, relieving cough and eliminating phlegm, and can be used for treating hypertension, hyperlipemia, hyperglycemia, fatty liver, etc. Has effects of protecting liver, removing toxic substances, lowering blood pressure, and reducing blood lipid and blood glucose.

In recent years, many herbal external products for preventing hair loss or promoting hair growth are sold worldwide, and these natural drugs have many advantages including strong adaptability, less side effects, easy availability, low cost, etc. compared with a single biochemical mode of action. However, the effect of plant extracts for alopecia treatment is still unsatisfactory and lacks novelty.

Disclosure of Invention

The invention aims to provide application of a gynostemma pentaphylla plant extract in preparing a medicine for promoting hair growth.

In order to achieve the above object, the present invention provides the following technical solutions:

the invention provides an application of a gynostemma pentaphylla plant extract solution in preparing a medicine for promoting hair growth.

Preferably, the application method comprises the following steps: the gynostemma pentaphylla plant extract is dissolved in tween 80 to prepare a gynostemma pentaphylla plant extract solution, and the solution can be applied to promoting hair growth.

Preferably, the concentration of the gynostemma pentaphylla plant extract solution is 50 mg/ml-800 mg/ml.

Preferably, the hair comprises hair.

The invention also provides a gynostemma pentaphylla plant extract solution used in the application.

The invention has the beneficial effects that: the gynostemma pentaphylla plant extract is applied to hair growth research, and specifically can promote the proliferation of human dermal papilla cells, increase the number of hair follicle cells, increase the growth length of hair follicles and increase the growth length of hairs, namely the gynostemma pentaphylla plant extract shows a remarkable hair growth effect.

Detailed Description

The invention provides an application of a gynostemma pentaphylla plant extract solution in preparing a medicine for promoting hair growth.

In the present invention, the application method is preferably: the gynostemma pentaphylla plant extract is dissolved in tween 80 to prepare a gynostemma pentaphylla plant extract solution, and the solution can be applied to promoting hair growth.

In the invention, the gynostemma pentaphylla plant extract is purchased from Shaanxi Baicao extraction Biotech Co., Ltd, and the Tween 80 is purchased from Nantong Orno chemical Co., Ltd.

In the present invention, the concentration of the gynostemma pentaphyllum plant extract solution is preferably 50mg/ml to 800mg/ml, more preferably 100mg/ml to 400mg/ml, and still more preferably 200mg/ml to 300 mg/ml.

In the present invention, the hair comprises hair.

The invention also provides a gynostemma pentaphylla plant extract solution used in the application.

The technical solutions provided by the present invention are described in detail below with reference to examples, but they should not be construed as limiting the scope of the present invention.