Medicine for treating cirrhosis and liver cancer and preparation method thereof

文档序号:1399661 发布日期:2020-03-06 浏览:31次 中文

阅读说明:本技术 一种治疗肝硬化、肝癌的药物及其制备方法 (Medicine for treating cirrhosis and liver cancer and preparation method thereof ) 是由 熊兴宣 于 2019-11-17 设计创作,主要内容包括:本发明公开了一种治疗肝硬化、肝癌的药物及其制备方法,该肝硬化、肝癌的药物,按重量份计,包括以下原料:制黄芪18-22份、瓜蒌皮13-17份、白芍38-42份、鳖甲8-12份、茵陈13-17份、柴胡13-17份、鸡内金28-32份、九香虫8-12份、合欢皮28-32份、乌梅13-17份、白花蛇草13-17份、全蝎5-7份、白蒺藜13-17份、蜈蚣2.5-3.5份、水獭5-7份、岩黄莲7-9份。其制备方法是按重量份取各原料药;将原料药用冷水浸泡18-22min,武火烧开后,文火熬35-45min,取水煎液即得。本发明的药物治疗肝硬化、肝癌具有起效快、疗效好、安全无毒副作用的特点。临床125例使用,总有效率94%。(The invention discloses a medicine for treating liver cirrhosis and liver cancer and a preparation method thereof, wherein the medicine for treating liver cirrhosis and liver cancer comprises the following raw materials in parts by weight: 18-22 parts of prepared astragalus membranaceus, 13-17 parts of trichosanthes kirilowii Maxim, 38-42 parts of radix paeoniae alba, 8-12 parts of turtle shell, 13-17 parts of oriental wormwood, 13-17 parts of radix bupleuri, 28-32 parts of endothelium corneum gigeriae galli, 8-12 parts of aspongopus, 28-32 parts of cortex albiziae, 13-17 parts of dark plum fruit, 13-17 parts of oldenlandia diffusa, 5-7 parts of scorpion, 13-17 parts of tribulus terrestris, 2.5-3.5 parts of centipede, 5-7 parts of otter and 7-9 parts of corydalis saxicola. The preparation method comprises the following steps of taking the raw material medicines in parts by weight; soaking the raw materials in cold water for 18-22min, boiling with strong fire, decocting with slow fire for 35-45min, and collecting water decoction. The medicine for treating liver cirrhosis and liver cancer has the characteristics of quick response, good curative effect, safety and no toxic or side effect. 125 clinical cases are used, and the total effective rate is 94%.)

1. A medicine for treating liver cirrhosis and liver cancer comprises the following raw materials in parts by weight:

18-22 parts of prepared astragalus membranaceus, 13-17 parts of trichosanthes kirilowii Maxim, 38-42 parts of radix paeoniae alba, 8-12 parts of turtle shell, 13-17 parts of oriental wormwood, 13-17 parts of radix bupleuri, 28-32 parts of endothelium corneum gigeriae galli, 8-12 parts of aspongopus, 28-32 parts of cortex albiziae, 13-17 parts of dark plum fruit, 13-17 parts of oldenlandia diffusa, 5-7 parts of scorpion, 13-17 parts of tribulus terrestris, 2.5-3.5 parts of centipede, 5-7 parts of otter and 7-9 parts of corydalis saxicola.

2. The medicine for treating liver cirrhosis and liver cancer as claimed in claim 1, comprises the following raw materials by weight:

20 parts of prepared astragalus membranaceus, 15 parts of trichosanthes peel, 40 parts of radix paeoniae alba, 10 parts of turtle shell, 15 parts of oriental wormwood, 15 parts of radix bupleuri, 30 parts of endothelium corneum gigeriae galli, 10 parts of aspongopus, 30 parts of cortex albiziae, 15 parts of dark plum fruit, 15 parts of oldenlandia diffusa, 6 parts of scorpion, 15 parts of tribulus terrestris, 3 parts of centipede, 6 parts of otter and 8 parts of corydalis saxicola.

3. The medicine for treating liver cirrhosis and liver cancer as claimed in claim 1 or 2, wherein the preparation method comprises the following steps:

(1) taking the raw materials in parts by weight;

(2) soaking the raw materials in cold water for 18-22min, boiling with strong fire, decocting with slow fire for 35-45min, and collecting water decoction.

Technical Field

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a medicine for treating liver cirrhosis and liver cancer, and a preparation method of the medicine for treating liver cirrhosis and liver cancer.

Background

Cirrhosis is a clinically common chronic progressive liver disease, a diffuse hepatic lesion formed by long-term or repeated action of one or more etiologies. In China, the majority of the patients are posthepatitic cirrhosis, and the minority of the patients are alcoholic cirrhosis and schistosomiasis cirrhosis. Histopathology includes extensive hepatocyte necrosis, nodular regeneration of residual hepatocytes, connective tissue hyperplasia and fibrosepta formation, which results in structural destruction of hepatic lobules and formation of pseudolobules, and the liver gradually deforms and hardens to develop cirrhosis. The liver compensation function is strong in the early stage, no obvious symptom exists, liver function damage and portal hypertension are mainly shown in the later stage, multiple systems are involved, and complications such as upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection, splenic hyperfunction, ascites, canceration and the like often appear in the later stage.

Liver cancer, a malignant tumor of the liver, can be divided into primary and secondary types. The primary liver malignant tumor originates from the epithelium or mesenchymal tissue of the liver, the former is called primary liver cancer, which is a highly-developed malignant tumor with great harm in China; the latter is called sarcoma, and is less common than primary liver cancer. Secondary or metastatic liver cancer refers to the invasion of malignant tumors of multiple organ origins in the whole body to the liver. Liver metastasis of malignant tumors of stomach, biliary tract, pancreas, colon, ovary, uterus, lung, and breast is common.

At present, the clinical treatment methods mainly comprise surgical treatment, chemical drug treatment, radiation treatment, biological treatment, traditional Chinese medicine treatment and the like. However, most western medicines have the defects of large side effect, high cost, difficulty in radical treatment and the like. The traditional Chinese medicine has small adverse reaction during treatment, but the existing traditional Chinese medicines are various in types, but the effects are different and not ideal.

Disclosure of Invention

The invention aims to provide a medicament for treating liver cirrhosis and liver cancer, which has the advantages of quick response, good curative effect and no toxic or side effect.

The invention also aims to provide a preparation method of the medicine for treating liver cirrhosis and liver cancer.

The invention relates to a medicine for treating liver cirrhosis and liver cancer, which comprises the following raw materials in parts by weight:

18-22 parts of prepared astragalus membranaceus, 13-17 parts of trichosanthes kirilowii Maxim, 38-42 parts of radix paeoniae alba, 8-12 parts of turtle shell, 13-17 parts of oriental wormwood, 13-17 parts of radix bupleuri, 28-32 parts of endothelium corneum gigeriae galli, 8-12 parts of aspongopus, 28-32 parts of cortex albiziae, 13-17 parts of dark plum fruit, 13-17 parts of oldenlandia diffusa, 5-7 parts of scorpion, 13-17 parts of tribulus terrestris, 2.5-3.5 parts of centipede, 5-7 parts of otter and 7-9 parts of corydalis saxicola.

The medicine for treating liver cirrhosis and liver cancer is prepared from the following raw materials in parts by weight:

20 parts of prepared astragalus membranaceus, 15 parts of trichosanthes peel, 40 parts of radix paeoniae alba, 10 parts of turtle shell, 15 parts of oriental wormwood, 15 parts of radix bupleuri, 30 parts of endothelium corneum gigeriae galli, 10 parts of aspongopus, 30 parts of cortex albiziae, 15 parts of dark plum fruit, 15 parts of oldenlandia diffusa, 6 parts of scorpion, 15 parts of tribulus terrestris, 3 parts of centipede, 6 parts of otter and 8 parts of corydalis saxicola.

The invention relates to a preparation method of a medicine for treating liver cirrhosis and liver cancer, which comprises the following steps:

(1) taking the raw materials in parts by weight;

(2) soaking the raw materials in cold water for 18-22min, boiling with strong fire, decocting with slow fire for 35-45min, and collecting water decoction. Compared with the prior art, the invention has obvious beneficial effects, and the technical scheme can show that: the invention adopts the processed astragalus root, snakegourd peel, white peony root, turtle shell, oriental wormwood, radix bupleuri, endothelium corneum gigeriae galli, aspongopus, cortex albiziae, dark plum fruit, oldenlandia diffusa, scorpion, tribulus terrestris, centipede, otter and corydalis saxicola bunting as raw materials, and achieves the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, soothing the liver and strengthening the spleen through the synergistic effect of the medicines, thereby achieving the purpose of treating cirrhosis and liver cancer. The medicine for treating liver cirrhosis and liver cancer has the characteristics of quick response, good curative effect, safety and no toxic or side effect. The traditional Chinese medicine is used in 43 clinical cases, and the total effective rate is 90%.

Detailed Description

The beneficial effects of the drug of the present invention are further illustrated by the following test examples.

Test example: clinical observations of the drug of the invention

1. Clinical data:

all 43 cases, of which: age 28-83 years, 26 men and 17 women.

2. Diagnostic criteria:

the standard of curative effect for diagnosing the diseases of the traditional Chinese medicine.

3. The treatment method comprises the following steps:

the medicine obtained by the invention is taken orally 3 times a day, each dose is one day, and 15 days are a treatment course.

4. The curative effect standard is as follows:

the effect is shown: disappearance of symptoms;

the method has the following advantages: the symptoms are obviously relieved;

and (4) invalidation: the symptoms are not obviously improved.

5. The treatment results are as follows:

the patients use the medicine of the invention, and the medicine has 32 cases of obvious effect, 7 cases of effective effect and 4 cases of ineffective effect. The significant efficiency is 74 percent, and the total effective rate is 90 percent.

The preparation of the present medicament is illustrated by the following examples.

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