阅读说明：本技术 一种具有清洁、杀菌、保湿作用的药液及其应用 (A medicinal liquid with cleaning, sterilizing and moisturizing effects, and its application ) 是由 洪滔 谢雨 刘莉 李守明 刘志勇 雷丹 丁龙艳 付宜谦 于 2020-01-19 设计创作，主要内容包括：本发明涉及中药与卫生技术领域,具体公开了一种具有清洁、杀菌、保湿作用的药液及其应用。所述的药液以质量百分比计,包含0.5-5.0%的江香薷提取物；所述的江香薷提取物以质量百分比计,含有不少于0.2%江香薷种籽提取物,该江香薷种籽提取物是对江香薷种籽采用超临界CO<Sub>2</Sub>萃取方式而获得的油性成分,所述的江香薷提取物还含有江香薷精油和/或江香薷水提液。该药液在制备卫生用品中具有广泛的应用,尤其是用该药液所制备的湿巾具有清洁、杀菌、保湿的三合一功能,并具有独特的中草药清香,纯植物提取不含人工合成香精,广大用户更易接受,具有较好的市场前景。(The invention relates to the technical field of traditional Chinese medicine and sanitation, and particularly discloses a liquid medicine with cleaning, sterilizing and moisturizing effects and application thereof. The liquid medicine comprises 0.5-5.0% of herba elsholtziae extract by mass percent; the elsholtzia splendens extract contains not less than 0.2 percent of elsholtzia splendens seed extract by mass percent, and the elsholtzia splendens seed extract adopts supercritical CO for elsholtzia splendens seeds 2 The elsholtzia extract also contains elsholtzia essential oil and/or elsholtzia water extract. The liquid medicine has wide application in preparing sanitary articles, especially wet tissue prepared from the liquid medicine has three-in-one functions of cleaning, sterilizing and moisturizing, has unique Chinese herbal medicine faint scent, is extracted from pure plants without artificially synthesized essence, is more acceptable by wide users, and has better market prospect.)

1. A liquid medicine with cleaning, sterilizing and moisturizing functions is characterized in that: the liquid medicine comprises 0.5-5.0% of herba elsholtziae extract by mass percent; the elsholtzia splendens extract contains not less than 0.2 percent of elsholtzia splendens seed extract by mass percent.

2. The liquid medicine with cleaning, sterilizing and moisturizing functions as claimed in claim 1, wherein the liquid medicine comprises the following components: the elsholtzia extract also contains elsholtzia essential oil and/or elsholtzia water extract.

3. The liquid medicine with cleaning, sterilizing and moisturizing effects as claimed in claim 1, wherein the extraction method of the seed extract comprises: by using supercritical CO₂Extracting the oily component.

4. The liquid medicine with cleaning, sterilizing and moisturizing effects as claimed in claim 3, wherein the supercritical CO is₂The extraction process specifically comprises the following steps: cleaning mature seeds, drying, pulverizing, sieving with 30-50 mesh sieve, weighing 1 weight part of seed powder, placing in extraction tank capable of accommodating 4-8 weight parts of seed powder, sealing system, and introducing CO₂As an extracting agent, opening after the extraction temperature reaches 54-56 DEG CExtracting at 54-56 deg.C and 49-51 deg.C respectively, controlling pressure of separation I at 6.8-7.2 MPa and pressure of separation II at 4.8-5.2 MPa, and separating I and II to obtain oily components, i.e. Elsholtzia splendens seed extract.

5. The liquid medicine with cleaning, sterilizing and moisturizing functions as claimed in claim 2, wherein the extraction method of the elsholtzia essential oil is as follows: dried whole grass of elsholtzia splendens is soaked in saline water, heated and cooked, circularly distilled, distilled and cooled to obtain oil phase fraction of elsholtzia splendens essential oil.

6. The liquid medicine with cleaning, sterilizing and moisturizing functions as claimed in claim 2, wherein the extraction method of the elsholtzia water extract is as follows: taking kilogram-liter or gram-milliliter as a weight-volume unit, soaking, boiling, concentrating and the like 5 parts by weight of dried whole grass of elsholtzia splendens to finally obtain 1 part by volume of elsholtzia splendens fluid extract.

7. The liquid medicine with cleaning, sterilizing and moisturizing functions as claimed in claim 2, wherein the liquid medicine comprises, by mass: 0.5 percent of Jiangxiang elsholtzia seed extract, 0.5 percent of Jiangxiang elsholtzia essential oil and 1 percent of Jiangxiang elsholtzia water extract.

8. Use of a liquid medicine having cleaning, sterilizing and moisturizing effects according to any one of claims 1 to 7 in the preparation of a hygienic article.

9. The use of a liquid medicine having cleaning, sterilizing and moisturizing effects as claimed in claim 8, wherein the sanitary product is a wet wipe.

Technical Field

The invention belongs to the technical field of traditional Chinese medicine and sanitation, and particularly relates to a liquid medicine with cleaning, sterilizing and moisturizing effects and application thereof.

Background

The wet tissue is a disposable cleaning sanitary article prepared by selecting a wet-strength soft-fiber high-permeability base material, folding, humidifying and packaging, and becomes an essential cleaning article in daily life of people due to the characteristics of basic functions of cleaning and moisturizing skin, convenience in carrying and the like. The antibacterial wet tissue is prepared by adding metals such as silver, copper and lead sulfite, benzalkonium chloride, benzethonium chloride, triclosan, chlorhexidine, alcohol and other chemical agents for inhibiting bacterial reproduction, but the components are often strong in smell and strong in irritation and can influence the health of human bodies. The addition of traditional Chinese medicine components is the most intensive place of wet tissue products in recent years, and medicines are reasonably designed according to different use objects.

Many ingredients in traditional Chinese medicines have the effects of resisting bacteria and diminishing inflammation, and gradually become the concerned field of adding liquid medicine into wet tissues, a plurality of wet tissues are using the ingredients of the traditional Chinese medicines to replace chemical ingredients or metal ingredients, for example, the application number is CN201410766023.3, the invention name is a private part cleaning and sanitary wet tissue and a preparation method thereof, the invention discloses the wet tissue which is developed and used for private parts by using the water extracts of panax notoginseng, day lily, sophora japonica branch, soya bean, licorice, artemisia rupestris, and the essential oil of geranium, lavender, frankincense, myrrh, chamomile, juniper and the like; also, for example, the application number is CN201510843842.8, the invention name is an antibacterial hand wiping wet tissue, and the invention discloses an antibacterial hand wiping wet tissue prepared by adding green tea essence or jasmine flower essence into extract of chamomile, aloe and calendula; the invention also discloses a tissue for disinhibiting and disinfecting for the small intestine and a preparation method thereof, and the tissue is prepared from magnolia officinalis alcohol extract, cnidium fruit volatile oil, senecio scandens alcohol extract, usnic acid and the like, wherein the application number is CN 201610081987.3; the invention discloses an organic anti-inflammatory and anti-allergy sanitary wet tissue prepared from fresh extract liquid of geranium, chamomile, purslane and aloe and a preparation method thereof, wherein the extract liquid of the fresh geranium, the chamomile, the purslane and the aloe are used for preparing the anti-inflammatory and anti-allergy sanitary wet tissue; however, the added combination of the wet tissues needs the synergy of a plurality of traditional Chinese medicines, the combination of the traditional Chinese medicines has difficult sources and complex process, some of the traditional Chinese medicines need fresh herbs, the difficulty is increased, and the formed liquid medicine has single function and generally mainly has the antibacterial and anti-inflammatory effects, so the application range is narrow and the universality is not realized.

At present, no wet tissue product containing the elsholtzia splendens extract exists in the market.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: aiming at the requirements of people on skin and hair cleaning and moistening at the same time and overcoming the defects of products in the market, the invention provides a medicinal liquid containing a elsholtzia haichowensis extract and an application thereof, wherein the medicinal liquid can improve the disinfection and sterilization performance and the moisture retention performance. The medicinal liquid contains Elsholtzia splendens extract. Can effectively moisturize and moisten skin and smooth and repair dry hair; can effectively clean skin and hair, and keep the skin and the hair clean and dry; can effectively resist and inhibit bacteria and maintain the health state of skin; the plant essence has unique Chinese herbal medicine faint scent, is extracted from pure plants without artificially synthesized essence, is more acceptable by wide users, and has better market application prospect.

The invention uses a traditional Chinese medicine of Jiang Xiang Moslae which can be used as medicine and food as a main medicine, and can obtain the liquid medicine for the wet tissue with three-in-one functions of cleaning, antibiosis, anti-inflammation and moisture retention by combining the seed extract, the water extract of the whole herb of the seed extract and volatile essential oil.

The invention adopts the following technical scheme to achieve the purpose of the invention.

Firstly, the invention discloses a liquid medicine with the functions of cleaning, sterilizing and moisturizing. The liquid medicine has three functions of cleaning, sterilizing and moisturizing.

A liquid medicine with cleaning, sterilizing and moisturizing effects comprises 0.5-5.0% of herba Elsholtziae seu Moslae extract by mass percent; the elsholtzia splendens extract contains not less than 0.2 percent of elsholtzia splendens seed extract by mass percent.

Furthermore, the elsholtzia extract also contains elsholtzia essential oil and/or elsholtzia water extract.

Preferably, the liquid medicine contains, by mass: 0.5 percent of Jiangxiang elsholtzia seed extract, 0.5 percent of Jiangxiang elsholtzia essential oil and 1 percent of Jiangxiang elsholtzia water extract.

Herba Moslae is Labiatae plant herba MoslaeMoslachinensisMax-imakOr herba MoslaeM.chinensis- jiangxiangru．Dried aerial parts of (1). It is recorded in the Ming Yi Bie Lu (miscellaneous records of famous physicians), listed as a middle-grade food, and has the actions of inducing sweat to relieve exterior syndrome, inducing diuresis to alleviate edema, regulating the middle warmer to resolve dampness, etc., with pungent and mild taste. The elsholtzia splendens extract contains aromatic substances, the aromatic substances can inhibit the activities of bacteria, viruses, anaerobes and acidogenesis, and can play a role in accelerating sweat volatilization, removing oil and sweatThe wet tissue keeps the theory of moist and dry state in the process of cleaning skin and hair and has good skin and hair care effect.

The fatty acid components such as linolenic acid in the elsholtzia seeds have the functions of effectively moisturizing, moistening skin and smoothing and repairing dry hair, so the three-effect liquid medicine for cleaning, sterilizing and moisturizing can be formed by adding the whole grass of the elsholtzia and the extract of the seeds.

Further, the extraction method of the seed extract comprises the following steps: by using supercritical CO₂Extracting the oily component.

Further, the supercritical CO₂The extraction process specifically comprises the following steps: cleaning mature seeds, drying, pulverizing, sieving with 30-50 mesh sieve, weighing 1 weight part of seed powder, placing in extraction tank capable of accommodating 4-8 weight parts of seed powder, sealing system, and introducing CO₂The preparation method comprises the steps of taking the extract as an extractant, starting extraction after the extraction temperature reaches 54-56 ℃, controlling the temperature of a separation I and the temperature of a separation II to be 54-56 ℃ and 49-51 ℃, respectively, controlling the pressure of the separation I to be 6.8-7.2 MPa, controlling the pressure of the separation II to be 4.8-5.2 MPa, and obtaining oily components by the separation I and the separation II after the extraction is finished, namely the elsholtzia splendens seed extract.

Compared with conventional squeezing extraction, the supercritical CO is adopted₂The extraction technology for extracting the elsholtzia seed extract can not only obviously improve the yield of the elsholtzia seed fatty oil, the yield of the elsholtzia seed fatty oil can be improved by more than 30 percent, but also can treat various active substances with the functions of cleaning, sterilizing and moisturizing, such as unsaturated fatty acids with rare content in seeds and the like in the elsholtzia seed by supercritical CO₂The extract can be more completely introduced into the seed extract of herba Elsholtziae seu Moslae, and can be subjected to supercritical CO extraction₂The quality of the elsholtzia splendens seed extract obtained by extraction is far superior to that of elsholtzia splendens seed fatty oil obtained by conventional squeezing extraction, and the elsholtzia splendens seed extract is subjected to supercritical CO treatment₂The obtained herba Elsholtziae seu Moslae seed extract has cleaning, sterilizing and moisture keeping effects.

Furthermore, the extraction method of the elsholtzia essential oil comprises the following steps: dried whole grass of elsholtzia splendens is soaked in saline water, heated and cooked, circularly distilled, distilled and cooled to obtain oil phase fraction of elsholtzia splendens essential oil.

Furthermore, the extraction method of the elsholtzia water extract comprises the following steps: taking kilogram-liter or gram-milliliter as a weight-volume unit, soaking, boiling, concentrating and the like 5 parts by weight of dried whole grass of elsholtzia splendens to finally obtain 1 part by volume of elsholtzia splendens fluid extract.

The invention also discloses application of the liquid medicine with the functions of cleaning, sterilizing and moisturizing in preparation of sanitary products.

The sanitary article is a wet tissue. The wet tissue has the three-in-one functions of cleaning, sterilizing and moisturizing. The invention uses a Chinese traditional medicine of Jiang Xiang Moslae which can be used as medicine and food as a main medicine, and can obtain the three-in-one liquid medicine for the wet tissue with the functions of cleaning, antibiosis, anti-inflammation and moisture preservation by combining the seed extract, the water extract of the whole herb of the seed extract and volatile essential oil, thereby having the capability of forming the multi-purpose wet tissue.

A wet towel with three-in-one functions of cleaning, sterilizing and moisturizing comprises wet towel medicinal liquid and base material carrying the medicinal liquid; the wet tissue liquid medicine comprises 0.5-5.0% of elsholtzia extract by mass percent, and the pH value of the liquid medicine is 3.5-8.5; the elsholtzia splendens extract contains not less than 0.2 percent of elsholtzia splendens seed extract by mass percent.

Furthermore, the elsholtzia extract also contains elsholtzia essential oil and/or elsholtzia water extract.

Further, the base material is non-woven fabric; the non-woven fabric is spunlace non-woven fabric or bamboo fiber non-woven fabric.

Furthermore, the wet tissue liquid medicine also comprises 0.01 to 2.0 percent of preservative, 0 to 10.0 percent of humectant, 0 to 5.0 percent of skin care agent, 0 to 0.5 percent of stabilizer, 0.01 to 2.0 percent of surfactant and a proper amount of acidity regulator in percentage by mass.

Still further, the preservative is selected from: geogard Ultra preservative, benzalkonium chloride, sodium methyl p-hydroxybenzoate and sodium salt thereof, ethyl p-hydroxybenzoate and sodium salt thereof, polyhexamethylene monoguanidine, polyhexamethylene biguanidine hydrochloride, phenoxyethanol, methylisothiazolinone, potassium sorbate, dehydroacetic acid, benzyl alcohol, dichlorobenzene, methanol, ethylhexyl glycerol, octanediol and the like, or a mixture of any one or more of the common preservatives. The antiseptic is added into the wet tissue liquid medicine for antisepsis.

Furthermore, the humectant is a polyhydric alcohol humectant, an amino acid humectant or other humectants; the polyalcohol humectant is any one or mixture of propylene glycol, glycerol and the like; the amino acid humectant is any one or mixture of glycine, sarcosine, alanine, proline, hydroxyproline and mixture thereof; the other moisturizers are any one or a mixture of more of collagen, milk protein, hyaluronic acid, sodium hyaluronate, oat glucan, oat protein, urea and derivatives thereof. The humectant is added into the wet tissue liquid medicine for keeping moisture.

Furthermore, the skin care agent is an oily skin care agent and/or a water-soluble skin care agent; the oily skin care agent is selected from one or more of vitamin E acetate, coenzyme Co-Q10, D-panthenol, wheat germ oil, mineral oil, castor oil, shea butter, sweet almond oil, pear oil, lanolin and derivatives thereof, methyl isostearate, isopropyl isostearate, vaseline and polydimethylsiloxane; the water-soluble skin care agent is selected from one or more of folium Artemisiae Argyi extract, fructus Actinidiae chinensis extract, soybean isoflavone extract, flos Lonicerae extract, grape seed extract, green tea extract, radix Puerariae extract, and flos Nelumbinis extract. The oily skin care agent and/or water-soluble skin care agent is added into the wet tissue liquid medicine for skin care.

Furthermore, the surfactant is selected from one or more of sodium cocoamphoacetate, disodium cocoamphodiacetate, cocobetaine and cocamidopropyl betaine. The surfactant is added into the wet tissue liquid medicine to reduce the surface tension.

Furthermore, the acidity regulator is selected from one or more of citric acid, sodium citrate, malic acid and lactic acid. The organic acid is used as acidity regulator in the wet tissue liquid medicine, so that the pH value is regulated, and irritation is avoided.

Further, the stabilizer is disodium EDTA or tetrasodium EDTA. The stabilizer is added into the wet tissue liquid medicine for stabilizing the product.

Further, the preparation method of the wet tissue comprises the following steps:

s1, preparing solution A and solution B:

solution A: respectively weighing herba Moslae chinensis extract (volatile oil or seed extract), oily skin caring agent, and surfactant according to wet towel liquid medicine ratio, mixing, heating to 50-60 deg.C for dissolving, and stirring for 10-15 min;

and B, liquid B: respectively weighing and mixing the water extract of elsholtzia splendens, the humectant and the preservative according to the proportion of the wet tissue liquid medicine, heating to 40-50 ℃ for dissolution, and uniformly stirring for 10-15 minutes;

s2, preparing wet tissue liquid medicine: according to the proportion of the wet tissue liquid medicine, firstly adding pure water into a stirring kettle, adding the liquid A under the stirring state, and slowly adding the liquid B after the pure water is completely dissolved; respectively adding the water-based skin care agent and the stabilizer under stirring until the skin care agent and the stabilizer are completely dissolved to form wet tissue liquid medicine, and regulating and controlling the pH value of the prepared wet tissue liquid medicine to be between 3.5 and 8.5 by using the acidity regulator;

s3, preparing wet tissues: humidifying the base material by using the wet tissue liquid medicine prepared in the step S2, controlling the liquid content of the wet tissue to be 3-6 times of the mass of the base material, and packaging by quality inspection to obtain the wet tissue containing the elsholtzia splendens.

Has the advantages that:

(1) the invention provides a medicinal liquid with cleaning, sterilizing and moisturizing functions, which contains Elsholtzia splendens seed extract component which adopts supercritical CO₂The elsholtzia seed extract has high-percentage linolenic acid component, and can effectively moisturize and moisten skin and smooth and repair dry hair.

(2) By using supercritical CO₂Extraction technology for extracting elsholtzia splendensSupercritical CO compared to conventional extraction by pressing₂The extraction technology can not only obviously improve the yield of the elsholtzia splendens seed fatty oil, the yield can be improved by more than 30 percent, but also can treat various active substances with the functions of cleaning, sterilizing and moisturizing in the elsholtzia splendens seeds, such as unsaturated fatty acids with rare content in the seeds and the like by supercritical CO₂The extract can be more completely introduced into the seed extract of herba Elsholtziae seu Moslae, and can be subjected to supercritical CO extraction₂The quality of the elsholtzia splendens seed extract obtained by extraction is far superior to that of elsholtzia splendens seed fatty oil obtained by conventional squeezing extraction, and the elsholtzia splendens seed extract is subjected to supercritical CO treatment₂The obtained herba Elsholtziae seu Moslae seed extract has cleaning, sterilizing and moisture keeping effects.

(3) The medicinal liquid with the functions of cleaning, sterilizing and moisturizing provided by the invention can effectively clean skin and hair and keep the skin and the hair in a clean and dry state due to the fact that the contained elsholtzia splendens extract contains water extract components.

(4) The medicinal liquid with the functions of cleaning, sterilizing and moisturizing provided by the invention contains volatile essential oil and water extract components in the elsholtzia haichowensis extract, so that the medicinal liquid can effectively resist and inhibit bacteria and maintain the health state of skin.

(5) The liquid medicine with the functions of cleaning, sterilizing and moisturizing provided by the invention has unique Chinese herbal medicine faint scent, and is extracted from pure plants without artificially synthesized essence, so that the liquid medicine is more acceptable to users.

(6) The wet tissue prepared by the liquid medicine containing the elsholtzia haichowensis extract fills the blank that the traditional Chinese medicine wet tissue product in the market has single function and no three-in-one function, and has better market prospect.

(7) The invention uses a Chinese traditional medicine of Jiang Xiang Moslae which can be used as medicine and food as a main medicine, and the liquid medicine for the wet tissue with three-in-one functions of cleaning, antibiosis, anti-inflammation and moisture retention can be obtained by combining the seed extract, the water extract of the whole herb of the seed extract and volatile essential oil.

(8) The preparation method of the wet tissue with the three-in-one functions of cleaning, sterilizing and moisturizing provided by the invention has the advantages of simple and convenient process method, conventional and universal equipment, stable and reliable product quality, and convenience for industrial, continuous and intelligent production.

Detailed Description

The present invention will be further described with reference to specific examples, but the present invention is not limited to the following examples. The method is a conventional method unless otherwise specified. The starting materials are commercially available from the open literature unless otherwise specified.