阅读说明：本技术 一种股骨头坏死膏药及其制备方法 (Plaster for treating femoral head necrosis and preparation method thereof ) 是由 王福昌 于 2018-09-03 设计创作，主要内容包括：本发明涉及一种股骨头坏死膏药及其制备方法,属中医药技术领域。本发明包括下述重量份的药物组成：细辛5-15克,徐长卿15-25克,生川乌5-15克,木瓜15-25克,透骨草15-25克,红花10-20克,乳香5-15克,土元5-15克,栀子5-15克,灵仙5-15克,生大黄1-10克,赤芍10-20克,红藤5-15克,冰片1-10克,杜仲5-15克,苍耳15-25克,羌活5-15克,独活5-15克,香油200-300克,松香100-200克。本发明提供的膏药原料易得、廉价,制备方法简便,容易被患者接受。(The invention relates to a plaster for treating femoral head necrosis and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. The invention comprises the following medicines in parts by weight: 5-15 g of asarum, 15-25 g of paniculate swallowwort root, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of gardenia, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of pubescent angelica root, 300 g of sesame oil 200-containing material and 200 g of rosin. The plaster provided by the invention has the advantages of easily available and cheap raw materials, simple and convenient preparation method and easy acceptance by patients.)

1. The plaster for treating femoral head necrosis is characterized by comprising the following medicaments in part by weight: 5-15 g of asarum, 15-25 g of paniculate swallowwort root, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of gardenia, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of pubescent angelica root, 300 g of sesame oil 200-containing material and 200 g of rosin.

2. The plaster for treating femoral head necrosis according to claim 1, wherein the plaster comprises: comprises the following components in parts by weight: 10 g of asarum, 20 g of paniculate swallowwort root, 10 g of unprocessed radix aconiti, 20 g of pawpaw, 20 g of garden balsam stem, 15 g of safflower, 10 g of frankincense, 10 g of eupolyphaga, 10 g of cape jasmine fruit, 10 g of clematis root, 5 g of unprocessed rhubarb, 15 g of red peony root, 10 g of sargentgloryvine stem, 5 g of borneol, 10 g of eucommia bark, 20 g of siberian cocklebur fruit, 10 g of notopterygium root, 10 g of radix angelicae pubescentis, 280 g of sesame oil and 160 g of.

3. The plaster for treating femoral head necrosis according to claim 1, wherein the plaster comprises: the method for preparing the invention comprises the following steps:

1) taking 5-15 g of asarum, 15-25 g of cynanchum paniculatum, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of cape jasmine, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of radix angelicae pubescentis, 300 g of sesame oil 200-containing materials, 200 g of rosin 100-containing materials, crushing, and sieving by a sieve of 80-;

2) heating sesame oil to 80 ℃, adding rosin, decocting until water drops into beads, removing fire, cooling to 240-260 ℃, adding frankincense, cooling to 70 ℃ after melting, pouring the medicine powder into a pot, uniformly stirring, cooling to 40 ℃, adding borneol, and decocting to obtain the plaster.

Technical Field

The invention relates to a plaster for treating femoral head necrosis and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.

Background

The femoral head necrosis is one of the common and intractable chronic diseases in orthopedics and traumatology, and is one of the diseases caused by hip trauma, long-term application of hormone medicine, alcoholism, etc. to result in blood supply disorder of femoral head, no normal nutrients to femoral head bone tissue and necrosis of bone cell, marrow hemopoietic cell and fat cell in femoral head tissue. Because the necrotic bone tissue is fragile, and the hip joint needs to bear weight, the femoral head can collapse over time, and all the hip joints are affected. Early symptoms of femoral head necrosis are: lumbago, hip pain, groin pain on the affected side, knee joint pain on the affected limb, aversion to cold, weakness, soreness and fatigue. These symptoms cannot appear simultaneously, and a person with two or more symptoms appears, and disappears after appearing in a short time, and repeats for many times. Is easily overlooked by patients; in the middle stage of femoral head necrosis, symptoms are gradually obvious, and the symptoms mainly comprise lameness, walking pain and dysfunction, when an X-ray is taken, most of trabecular bone can be seen to disappear, the saccular change is caused, the bone is hardened, the femoral head cartilage is broken and collapsed, and the like; in late femoral head necrosis, the lameness of a patient is more serious, the patient obviously feels short legs, walking is difficult and painful, the femoral head necrosis such as the flat femoral head, collapse, the narrow or disappearance of joint gaps, obvious change of saccular shape, large sclerotin hardening area, complete fracture of femoral head cartilage, rough joint surface and the like can be seen by an X-ray, the femoral head necrosis is a pathological evolution process, and the most common symptoms are the lameness, the walking pain and the continuous pain and the resting pain. The limited movement of the femoral head brings great pain to the patient.

Therefore, a plaster which can treat femoral head necrosis and has a repairing function on the damaged femoral head is urgently needed in the market.

Disclosure of Invention

The invention provides a plaster for treating femoral head necrosis and a preparation method thereof, aiming at solving the problems.

In order to achieve the purpose, the invention adopts the following scheme:

the invention comprises the following medicines in parts by weight: 5-15 g of asarum, 15-25 g of paniculate swallowwort root, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of gardenia, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of pubescent angelica root, 300 g of sesame oil 200-containing material and 200 g of rosin.

The invention comprises the following medicine components with the preferred weight portions: 10 g of asarum, 20 g of paniculate swallowwort root, 10 g of unprocessed radix aconiti, 20 g of pawpaw, 20 g of garden balsam stem, 15 g of safflower, 10 g of frankincense, 10 g of eupolyphaga, 10 g of cape jasmine fruit, 10 g of clematis root, 5 g of unprocessed rhubarb, 15 g of red peony root, 10 g of sargentgloryvine stem, 5 g of borneol, 10 g of eucommia bark, 20 g of siberian cocklebur fruit, 10 g of notopterygium root, 10 g of radix angelicae pubescentis, 280 g of sesame oil and 160 g of.

In the components of the invention:

paniculate swallowwort root, also called ghost Potentilla chinensis, Cynanchum paniculatum, rhizoma paridis, Bianxiaozong, Xiaoyao bamboo, herba solidaginis, fishing rod, herons grass, peristrophe grass, radix bupleuri, etc. Is root and rhizome of Cynanchum paniculatum (Cynanchum paniculatum) or whole plant with root. It can be used internally or externally. Mainly produced in Zhejiang, Jiangsu, Hunan, Hubei, etc. Collected in summer and autumn, removed impurities, cut, dried and used as medicine. The invention has the functions of easing pain, inducing diuresis to alleviate edema, promoting blood circulation to remove toxin and the like.

The asarum, also called as asarum, etc., belongs to the aristolochiales, aristolochiaceae perennial herbs, and has the functions of dispelling wind, dispelling cold, promoting diuresis and inducing resuscitation.

Unprocessed radix aconiti, the English name Aconite Root, the alias of Chinese gooseberry flower and Tiehua, and is nontoxic. Growing in a mountain grass slope or irrigation clusters. Cultivated in sandy soil with fertile flat land, mainly cultivated in Sichuan. Distributed in the middle and lower reaches of the Yangtze river, from the north to the Qinling mountain, from the east of the mountain, and from the south to the north of Guangxi. The invention has the functions of dispelling wind and removing dampness, warming meridians and relieving pain.

Papaya is a dried mature fruit of chaenomeles speciosa belonging to the family Rosaceae. Collected in summer and autumn when the fruit is green and yellow, scalded in boiling water until the outer skin is grey white, split into halves and longitudinally cut, and then dried in the sun. The pawpaw has the effects of resisting bacteria and tumors, removing dampness and removing arthralgia, relaxing tendons and activating collaterals and the like.

Garden balsam stem (scientific name: Phyma leptostachya L.subsp.asitica (Hara) Kitamura) is also known as herb of Chinese Quercus, Musca et Persica, etc. Perennial herbs are selected from the whole plant. The whole herb is green, dry, tender and free of impurities. It is used for treating common cold, traumatic injury, and external application for treating toxic sore, eczema, and scabies.

Safflower, also known as Caohong thorn safflower, Du hong Hua and jin hong Hua. Dicotyledons, Compositae, have a specific fragrance and a slightly bitter taste. The preferred one is long, bright red, soft. The invention has the effects of promoting blood circulation, stimulating the menstrual flow, dissipating blood stasis, relieving pain and the like.

Frankincense, name of traditional Chinese medicine. Is called as incense of Lu. Is resin exuded from bark of Boswellia carterii Birdw of Boswellia carterii of Burseraceae and Boswellia bhauradaizha Birdw of the same genus. The product has obvious pain relieving effect, regulates qi and activates blood, relieves pain, treats toxin, and has good effects of treating stagnation of qi and blood, carbuncle sore and pyogenic infections, traumatic injury and the like.

Ground beetle, another name: eupolyphaga Seu Steleophaga, street, Eupolyphaga Seu Steleophaga, Arthropoda Kaempferi, Eupolyphaga Seu Steleophaga, and Eupolyphaga Seu Steleophaga. It belongs to insects, with flat body, brown black, male wings and female wings. Often move in the soil of the wall root of the house. Can be used as medicine. The invention has the effects of breaking blood and removing stasis, promoting reunion of fractured bones and the like.

Gardenia jasminoides is named as gardenia jasminoides ellis, gardenia grandiflorum, magnolia denudata, gardenia macrocephala, gardenia rubra and Huangguoshu. The invention has the functions of clearing heat, purging fire and cooling blood. It is indicated for sores and ulcers due to heat-toxicity, sprain, swelling and pain.

The Chinese medicine of the present invention has the functions of dispelling wind and eliminating dampness, promoting blood circulation to disperse meridian obstruction, detoxicating and eliminating mass.

The raw rhubarb is a collective name of a plurality of perennial plants in rhubarb of Polygonaceae, is also a name of traditional Chinese medicinal materials, and has the effects of clearing damp-heat, purging intense heat, cooling blood, removing blood stasis, detoxifying and the like.

Radix Paeoniae Rubra mainly comprises paeoniflorin, albiflorin, oxypaeoniflorin, benzoylpaeoniflorin, Paeoniflorin, paeoniflorin, daucosterol, and optionally radix Paeoniae Rubra extract (d-catechin), gallotannin, and benzoic acid. The invention has the functions of clearing heat, easing pain, calming, relieving spasm, promoting blood circulation to remove blood stasis, improving the oxygenation function of blood, resisting tumor and resisting pathogenic microorganism.

Caulis Sargentodoxae is the rattan of Sargentodoxa cuneata of the family Akebia, dicotyledonous. Alias: sargentgloryvine stem, homalomena occulta, sargentgloryvine stem and kadsura pepper stem. The cool and detoxicating Chinese medicine has the functions of promoting blood circulation to disperse meridian obstruction, detoxicating, dissipating blood stasis, dispelling wind and killing pests.

Borneol is a common clinical traditional Chinese medicine, has the effects of restoring consciousness, inducing resuscitation, clearing heat, relieving pain, preventing corrosion and promoting granulation, and has bidirectional regulation and protection effects on the central nervous system. Promoting wound healing, and the borneol can increase granulation tissue structure and epidermal cell regeneration, repair skin accessory organs and has stronger wound healing effect. And has antibacterial, antiinflammatory, and analgesic effects.

Eucommia ulmoides is the dried bark of eucommia ulmoides oliv of the family eucommia ulmoides and is a famous and precious Chinese medicinal material for nourishing. Growing in mountain forest or cultivating. Distributed in the middle and south provinces of the Yangtze river, Henan, Shaanxi, Gansu, etc. The invention has the functions of preventing and treating arteriosclerosis, strengthening muscles and bones, resisting tumors and the like.

The invention relates to a fructus xanthil, which belongs to a rheumatism-expelling traditional Chinese medicine and has the efficacies of dispelling wind cold, expelling wind-damp, relieving pain and the like.

Notopterygium root, Notopterygium, and black drug, all of the plants of the family Umbelliferae, genus Notopterygium, a perennial herb, 60-120 cm high, thick and long rhizome in bamboo joint shape. The neck of the root has withered leaf sheath. The stem is upright, cylindrical, hollow, has straight and thin stripes and is purple. The invention mainly plays a role in dispelling cold and dampness.

Pubescent angelica root, name of Chinese traditional medicine. Is dried root of Angelica gigas nakai of Umbelliferae, Angelica pubescens Maxim.f. biserrata Shann et Yuan. Digging when seedlings just sprout in the early spring or when stems and leaves wither in the late autumn, removing fibrous roots and silt, drying to be semi-dry, piling for 2-3 days, softening and then drying to be completely dry. The invention has the effects of dispelling wind and eliminating dampness, dispelling cold and relieving pain and the like.

The sesame oil is used as a blending agent in the traditional Chinese medicine formula and has the effect of moistening the skin.

The rosin is a transparent or semitransparent irregular block, and has the effects of dispelling wind and eliminating dampness, drawing out toxin and expelling pus, promoting granulation and relieving pain and the like.

The method for preparing the invention comprises the following steps:

1) taking 5-15 g of asarum, 15-25 g of paniculate swallowwort root, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of cape jasmine fruit, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of pubescent angelica root, 300 g of sesame oil 200-containing material and 200 g of rosin, crushing the materials and sieving the crushed materials by a sieve of 80-120 meshes.

2) Heating sesame oil to 80 ℃, adding rosin, decocting until water drops into beads, removing fire, cooling to 240-260 ℃, adding frankincense, cooling to 70 ℃ after melting, pouring the medicine powder into a pot, uniformly stirring, cooling to 40 ℃, adding borneol, and decocting to obtain the plaster.

The plaster provided by the invention has the advantages of easily available and cheap raw materials and simple and convenient preparation method. Is easily accepted by patients.

Detailed Description

The invention comprises the following medicines in parts by weight: 5-15 g of asarum, 15-25 g of paniculate swallowwort root, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of gardenia, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of pubescent angelica root, 300 g of sesame oil 200-containing material and 200 g of rosin.

The invention comprises the following medicine components with the preferred weight portions: 10 g of asarum, 20 g of paniculate swallowwort root, 10 g of unprocessed radix aconiti, 20 g of pawpaw, 20 g of garden balsam stem, 15 g of safflower, 10 g of frankincense, 10 g of eupolyphaga, 10 g of cape jasmine fruit, 10 g of clematis root, 5 g of unprocessed rhubarb, 15 g of red peony root, 10 g of sargentgloryvine stem, 5 g of borneol, 10 g of eucommia bark, 20 g of siberian cocklebur fruit, 10 g of notopterygium root, 10 g of radix angelicae pubescentis, 280 g of sesame oil and 160 g of.

The preparation method is described in detail below with reference to the pharmaceutical components of the present invention:

1) taking 5-15 g of asarum, 15-25 g of paniculate swallowwort root, 5-15 g of unprocessed radix aconiti, 15-25 g of pawpaw, 15-25 g of garden balsam stem, 10-20 g of safflower, 5-15 g of frankincense, 5-15 g of eupolyphaga, 5-15 g of cape jasmine fruit, 5-15 g of clematis root, 1-10 g of unprocessed rheum officinale, 10-20 g of red peony root, 5-15 g of sargentgloryvine stem, 1-10 g of borneol, 5-15 g of eucommia bark, 15-25 g of siberian cocklebur fruit, 5-15 g of notopterygium root, 5-15 g of pubescent angelica root, 300 g of sesame oil 200-containing material and 200 g of rosin, crushing the materials and sieving the crushed materials by a sieve of 80-120 meshes.

2) Heating sesame oil to 80 ℃, adding rosin, decocting until water drops into beads, removing fire, cooling to 240-260 ℃, adding frankincense, cooling to 70 ℃ after melting, pouring the medicine powder into a pot, uniformly stirring, cooling to 40 ℃, adding borneol, and decocting to obtain the plaster.

When the femoral head necrosis is treated, the plaster for the femoral head necrosis is coated on the femoral head necrosis part for 2-3 times a day. In recent years, tracking treatment of hundreds of patients shows that the effect rate is as high as ninety-five percent or more.

The above preferred embodiments are not intended to limit the present invention, and the present invention is not limited to the above embodiments, and those skilled in the art should also make changes, modifications, additions or substitutions within the scope of the present invention.