阅读说明：本技术 一种室温制备四硼化钇纳米粒子的方法 (Method for preparing yttrium tetraboride nanoparticles at room temperature ) 是由 童东革 向桓冬 周瑞 于 2019-12-18 设计创作，主要内容包括：本发明公开了一种四硼化钇纳米粒子的制备方法。本发明通过液相等离子体,在室温于1-丁基-2,3-二甲基咪唑双(三氟甲烷磺酰)亚胺盐离子液体中,通过硼烷还原YCl<Sub>3</Sub>合成出四硼化钇纳米粒子。与商用四硼化钇相比,本发明所制备的四硼化钇纳米粒子比表面积更大,抑菌效果更强。与丁胺卡那霉素和硫酸威替米星相比,本发明所制备的四硼化钇纳米粒子对类鼻疽假单胞菌表现出了更强的抗菌活性。其优异的类鼻疽假单胞菌抑菌功能使四硼化钇有望在人和动物等创伤临床治疗领域方面得到广泛应用。(The invention discloses a preparation method of yttrium tetraboride nanoparticles. The YCl is reduced by borane in 1-butyl-2, 3-dimethyl imidazole bis (trifluoromethanesulfonyl) imide salt ionic liquid at room temperature through liquid-phase plasma 3 Synthesizing the yttrium tetraboride nano particles. Compared with commercial yttrium tetraboride, the yttrium tetraboride nanoparticles prepared by the method have larger specific surface area and stronger antibacterial effect. Compared with amikacin and wittigmine sulfate, the yttrium tetraboride nanoparticles prepared by the invention have stronger antibacterial activity on pseudomonas pseudomelioidea. The excellent bacteriostatic function of the pseudomonas pseudomelioidis enables the yttrium tetraboride to be expected to be widely applied in the field of clinical treatment of wounds of human beings, animals and the like.)

1. A method for preparing yttrium tetraboride nanoparticles at room temperature is characterized by comprising the following steps: the preparation method comprises the following specific steps:

(1) mixing 2.7mmol YCl₃Adding 33mL of 1-butyl-2, 3-dimethylimidazolium bis (trifluoromethanesulfonyl) imide salt ionic liquid, and stirring for 27 minutes under the protection of argon to form a solution;

(2) transferring the mixed solution obtained in the step (1) into a 50mL reaction kettle under the protection of argon, introducing borane into the reaction kettle, and enabling the borane and YCl to react₃The molar ratio of (1) to (6-10), and sealing the reaction kettle;

(3) starting liquid phase plasma with the power of 400-;

(4) washing the product with deionized water for three times, then washing the product with absolute ethyl alcohol for three times, and drying the product for later use.

2. The method of preparing yttrium tetraboride nanoparticles according to claim 1, wherein: in the step (2), the borane and YCl are introduced₃Is 8: 1.

3. The method of preparing yttrium tetraboride nanoparticles according to claim 1, wherein: in the step (3), the power of the liquid phase plasma is 600W.

4. The method of preparing yttrium tetraboride nanoparticles according to claim 1, wherein: in the step (3), the reaction time is 45 min.

Technical Field

The invention relates to a method for preparing yttrium tetraboride nanoparticles at room temperature, and belongs to the technical field of advanced nano material preparation.

Background

The yttrium tetraboride is a high-temperature thermoelectric material and is widely used in the fields of hypersonic aircrafts, rockets and the like. It is generally prepared by a high-temperature sintering method, and is not only energy-consuming, but also time-consuming. Therefore, it is very necessary to develop a new green synthesis method or a new technical approach to prepare yttrium tetraboride.

Disclosure of Invention

The invention adopts liquid phase plasma technology to prepare 1-butyl at room temperature for the first timeReduction of YCl by borane in (2, 3-dimethyl) imidazolium bis (trifluoromethanesulfonyl) imide salt ionic liquids₃The synthesized yttrium tetraboride nano particles have the average particle size of about 3.3nm and simultaneously have excellent bacteriostatic activity of pseudomonas pseudomelioidis. Pseudomonas pseudomelioidis can cause gangrene of the human body through trauma and infect animals such as horses, cattle, sheep, pigs, dogs, cats and the like. For human beings, pseudomonas pseudomelioidis can invade every organ in the human body, and the misdiagnosis rate is extremely high. With the lungs being the most common type of infection, manifested as primary or disseminated pneumonia of blood origin.

The invention adopts the following technical scheme:

the preparation method of the yttrium tetraboride nano particles comprises the following specific steps:

(1) mixing 2.7mmol YCl₃Adding 33mL of 1-butyl-2, 3-dimethylimidazolium bis (trifluoromethanesulfonyl) imide salt ionic liquid, and stirring for 27 minutes under the protection of argon to form a solution;

(2) transferring the mixed solution obtained in the step (1) into a 50mL reaction kettle under the protection of argon, introducing borane into the reaction kettle, and enabling the borane and YCl to react₃The molar ratio of (1) to (6-10), and sealing the reaction kettle;

(3) starting liquid phase plasma with the power of 400-;

(4) washing the product with deionized water for three times, then washing the product with absolute ethyl alcohol for three times, and drying the product for later use.

In step (2), preferably under argon atmosphere and with borane and YCl₃Introducing borane into the mixed liquid in the step (1) at a molar ratio of 8:1, and sealing the reaction kettle.

In the step (3), the power of the liquid phase plasma is preferably 600W.

In the step (3), the reaction time is preferably 45 min.

The invention has the following positive effects:

1) the invention successfully synthesizes the yttrium tetraboride nano particles at room temperature for the first time by adopting a liquid phase plasma technology.

2) Compared with commercial yttrium tetraboride, the yttrium tetraboride nano particles synthesized by the method have larger specific surface area.

3) Compared with commercial yttrium tetraboride, the yttrium tetraboride nanoparticles synthesized by the method have stronger antibacterial activity.

4) Compared with amikacin and wittigmine sulfate, the yttrium tetraboride nanoparticles synthesized by the method have stronger antibacterial activity on pseudomonas pseudomelioidea.

Drawings

FIG. 1 is a TEM photograph of yttrium tetraboride nanoparticles prepared in example 1.

FIG. 2 is an X-ray diffraction pattern of yttrium tetraboride nanoparticles prepared in example 1.

FIG. 3 is a Y3dXPS spectrum of yttrium tetraboride nanoparticles prepared in example 1.

FIG. 4 is a B1sXPS spectrum of yttrium tetraboride nanoparticles prepared in example 1.

Detailed Description

The following examples are further detailed descriptions of the present invention.

The experimental procedures used in the following examples are all conventional procedures unless otherwise specified.

Materials, reagents and the like used in the following examples are commercially available unless otherwise specified.