Traditional Chinese medicine composition for clearing heat and purging fire and preparation method thereof

文档序号:1512186 发布日期:2020-02-11 浏览:33次 中文

阅读说明:本技术 一种清热泻火的中药组合物及其制备方法 (Traditional Chinese medicine composition for clearing heat and purging fire and preparation method thereof ) 是由 张丽慧 万韬 王俊 李威 黄彦辉 于 2019-11-07 设计创作,主要内容包括:本发明公开了一种清热泻火的中药组合物及其制备方法,要解决的是现有清热泻火药物效果不佳的问题。本发明包括以下重量份的原料:大黄膏250~300份、黄芩膏175~200份、黄连膏82.5~115.2份、淀粉200~255份、羧甲淀粉钠20~26份、硬脂酸镁5.2~5.9份和包衣剂11~13.4份。本产品通过黄连、大黄、黄芩的配合,具有清热泻火解毒和化瘀凉血止血的作用,用于火毒血热所致的身热烦燥,目赤口疮,咽喉、牙龈肿痛,大便秘结、吐血,咯血、衄血,痔血等症;可以治疗咽炎、扁体炎和牙龈炎。(The invention discloses a traditional Chinese medicine composition for clearing heat and purging fire and a preparation method thereof, and aims to solve the problem that the traditional heat-clearing and purging fire medicine is poor in effect. The invention comprises the following raw materials in parts by weight: 250-300 parts of rhubarb ointment, 175-200 parts of scutellaria ointment, 82.5-115.2 parts of coptis ointment, 200-255 parts of starch, 20-26 parts of carboxymethyl starch sodium, 5.2-5.9 parts of magnesium stearate and 11-13.4 parts of coating agent. The product has the effects of clearing heat, purging fire, detoxifying, removing blood stasis, cooling blood and stopping bleeding by matching the coptis, the rhubarb and the scutellaria, and is used for treating fever, fantod, conjunctival congestion, aphtha, sore throat, gum swelling and pain, constipation, hematemesis, hemoptysis, epistaxis blood, hemorrhoidal bleeding and other symptoms caused by fire toxin and blood heat; can be used for treating pharyngitis, tonsillitis and gingivitis.)

1. The traditional Chinese medicine composition for clearing heat and purging fire is characterized by comprising the following raw materials in parts by weight: 250-300 parts of rhubarb ointment, 175-200 parts of scutellaria ointment, 82.5-115.2 parts of coptis ointment, 200-255 parts of starch, 20-26 parts of carboxymethyl starch sodium, 5.2-5.9 parts of magnesium stearate and 11-13.4 parts of coating agent.

2. The heat-clearing fire-purging traditional Chinese medicine composition according to claim 1, wherein the preparation methods of the rhubarb ointment, the scutellaria ointment and the coptis ointment are as follows: decocting the raw materials with water twice, adding water 10 times of the weight of the raw materials for the first time, decocting for 1-2 hours, adding water 8 times of the weight of the raw materials for the second time, decocting for 0.8-1.4 hours, filtering, combining the decoction, and concentrating the decoction under reduced pressure to obtain thick paste with the relative density of 1.25 at 70 ℃.

3. The heat-clearing fire-purging traditional Chinese medicine composition according to claim 1, wherein the starch is corn starch.

4. The heat-clearing fire-purging traditional Chinese medicine composition according to claim 2, characterized in that the raw materials are selected, cleaned and soaked before being decocted with water.

5. The heat-clearing and fire-purging traditional Chinese medicine composition according to claim 2 or 4, wherein the temperature of the reduced pressure concentration is 70-80 ℃, the vacuum degree is-0.05-0.08 MPa, and the steam pressure is 0.05-0.2 MPa.

6. A preparation method of the traditional Chinese medicine composition for clearing heat and purging fire according to any one of claims 1 to 5 is characterized by comprising the following specific steps:

step one, weighing raw materials according to a formula for later use;

step two, mixing starch and part of carboxymethyl starch sodium to obtain a first mixture, adding rheum officinale paste, scutellaria baicalensis paste and coptis chinensis paste into the first mixture, and uniformly mixing to obtain a second mixture;

step three, mixing the second mixture, magnesium stearate and the residual carboxymethyl starch sodium to obtain a third mixture;

and step four, tabletting the third mixture, matching a coating agent and a proper amount of water into a coating solution, adding the coating solution into the tabletted third product, cooling, and then inspecting and packaging to obtain a finished product.

7. The preparation method of the traditional Chinese medicine composition for clearing heat and purging fire according to claim 6, wherein the weight ratio of the coating agent to water is 6: 36.5-39.2.

Technical Field

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for clearing heat and purging fire.

Background

Traditional Chinese medicine is a magnificent wonderful flower in various gardens of world medicine, and in the long rivers of thousands of years of history, the traditional Chinese medicine once made an outstanding contribution to the health career of our nationality, and nowadays when various diseases are increased day by day, the traditional Chinese medicine is a medicine mainly based on herbaceous plant and human medicine, and has unique effects on disease prevention and health preservation of people.

Clearing heat is a term of traditional Chinese medicine, referring to various therapeutic methods for clearing pathogenic heat or deficiency heat, and the heat syndrome includes the difference of heat in qi system, nutrient system, blood system, deficiency heat, excess heat and so on, so the clearing method can be divided into four kinds of herbs for clearing heat and purging fire, clearing heat and cooling blood, clearing heat and removing toxicity, and clearing heat and drying dampness. Heat clearing and fire purging are needed by many people, but no heat clearing and fire purging medicine with good use effect exists at present, and people also carry out research on relevant aspects.

Disclosure of Invention

The embodiment of the invention aims to provide a traditional Chinese medicine composition for clearing heat and purging fire, which is used for solving the problems in the background technology.

In order to achieve the above purpose, the embodiments of the present invention provide the following technical solutions:

a traditional Chinese medicine composition for clearing heat and purging fire comprises the following raw materials in parts by weight: 250-300 parts of rhubarb ointment, 175-200 parts of scutellaria ointment, 82.5-115.2 parts of coptis ointment, 200-255 parts of starch, 20-26 parts of carboxymethyl starch sodium, 5.2-5.9 parts of magnesium stearate and 11-13.4 parts of coating agent.

As a further scheme of the embodiment of the invention: the preparation methods of the rhubarb ointment, the scutellaria ointment and the coptis ointment are as follows: decocting the raw materials with water twice, adding water 10 times of the weight of the raw materials for the first time, decocting for 1-2 hours, adding water 8 times of the weight of the raw materials for the second time, decocting for 0.8-1.4 hours, filtering, combining the decoction, and concentrating the decoction under reduced pressure to obtain thick paste with the relative density of 1.25 at 70 ℃.

As a further scheme of the embodiment of the invention: the starch is corn starch, and the filling and bonding effects are good.

As a further scheme of the embodiment of the invention: the raw materials are carefully selected, cleaned and soaked before being decocted with water, so that the purity of the thick paste is ensured.

As a further scheme of the embodiment of the invention: the temperature of the reduced pressure concentration is 70-80 ℃, the vacuum degree is-0.05-0.08 MPa, and the steam pressure is 0.05-0.2 MPa.

A preparation method of a traditional Chinese medicine composition for clearing heat and purging fire comprises the following specific steps:

step one, weighing raw materials according to a formula for later use;

step two, mixing starch and part of carboxymethyl starch sodium to obtain a first mixture, adding rheum officinale paste, scutellaria baicalensis paste and coptis chinensis paste into the first mixture, and uniformly mixing to obtain a second mixture;

step three, mixing the second mixture, magnesium stearate and the residual carboxymethyl starch sodium to obtain a third mixture;

and step four, tabletting the third mixture, matching a coating agent and a proper amount of water into a coating solution, adding the coating solution into the tabletted third product, cooling, and then inspecting and packaging to obtain a finished product.

As a further scheme of the embodiment of the invention: the magnesium stearate is sieved by a sieve of 80 meshes before use, and the starch and the sodium carboxymethyl starch are sieved by a sieve of 100 meshes before use, so that the uniformity of all raw materials in a finished product is ensured.

As a further scheme of the embodiment of the invention: the weight ratio of the coating agent to the water is 6: 36.5-39.2.

Compared with the prior art, the embodiment of the invention has the beneficial effects that:

the product has the effects of clearing heat, purging fire, detoxifying, removing blood stasis, cooling blood and stopping bleeding by matching the coptis, the rhubarb and the scutellaria, and is used for treating fever, fantod, conjunctival congestion, aphtha, sore throat, gum swelling and pain, constipation, hematemesis, hemoptysis, epistaxis blood, hemorrhoidal bleeding and other symptoms caused by fire toxin and blood heat; can be used for treating pharyngitis, tonsillitis and gingivitis.

Detailed Description

The technical solution of the present patent will be described in further detail with reference to the following embodiments.

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