阅读说明：本技术 一种化学发光免疫分析仪 (Chemiluminescence immunoassay appearance ) 是由 余正洋 黄先桃 黄跃东 于 2019-11-14 设计创作，主要内容包括：本发明涉及医疗器械,具体涉及一种化学发光免疫分析仪,包括：反应杯加载装置,包括容纳腔、与容纳腔连接的输送通道、与输送通道下端配合连接的进杯部；样本试剂装置；孵育清洗装置,包括用于放置反应杯并对反应杯中的样本进行孵育的孵育盘、用于对反应杯中的磁微粒进行清洗的清洗盘、用于带动孵育盘和清洗盘转动的第二驱动组件；孵育盘和清洗盘上均设有用于放置反应杯的放置位,孵育盘和清洗盘同心设置,孵育盘位于进杯部的下方；采样装置；反应杯抓取装置；检测装置；控制系统；机架。本发明能够简化现有结构,缩小仪器体积。(The invention relates to a medical apparatus, in particular to a chemiluminescence immunoassay analyzer, which comprises: the reaction cup loading device comprises an accommodating cavity, a conveying channel connected with the accommodating cavity and a cup entering part connected with the lower end of the conveying channel in a matching way; a sample reagent device; the incubation cleaning device comprises an incubation disc, a cleaning disc and a second driving assembly, wherein the incubation disc is used for placing the reaction cup and incubating a sample in the reaction cup, the cleaning disc is used for cleaning magnetic particles in the reaction cup, and the second driving assembly is used for driving the incubation disc and the cleaning disc to rotate; the incubation disc and the cleaning disc are both provided with placing positions for placing reaction cups, the incubation disc and the cleaning disc are concentrically arranged, and the incubation disc is positioned below the cup inlet part; a sampling device; a reaction cup gripping device; a detection device; a control system; and a frame. The invention can simplify the existing structure and reduce the volume of the instrument.)

1. A chemiluminescent immunoassay analyzer, comprising:

the reaction cup loading device is used for loading a reaction cup and comprises an accommodating cavity, a conveying channel connected with the accommodating cavity and a cup inlet part matched and connected with the lower end of the conveying channel;

the sample reagent device comprises a sample disc for placing a sample, a reagent disc for placing a reagent, and a first driving assembly for driving the sample disc and the reagent disc to rotate;

the incubation cleaning device comprises an incubation disc, a cleaning disc and a second driving assembly, wherein the incubation disc is used for placing the reaction cup and incubating a sample in the reaction cup, the cleaning disc is used for cleaning magnetic particles in the reaction cup, and the second driving assembly is used for driving the incubation disc and the cleaning disc to rotate; the incubation disc and the cleaning disc are both provided with placing positions for placing reaction cups, the incubation disc and the cleaning disc are concentrically arranged, and the incubation disc is positioned below the cup inlet part;

the sampling device comprises a sampling arm, a sampling needle, a sampling driving assembly and a cleaning pool, wherein the sampling needle is arranged on the sampling arm, the sampling driving assembly is used for driving the sampling arm and the sampling needle to move, the cleaning pool is used for cleaning the sampling needle, and the movement track of the sampling needle is intersected with the sample disc, the reagent disc, the incubation disc and the cleaning pool;

the reaction cup grabbing device is used for grabbing and transferring the reaction cups between the incubation disc and the cleaning disc;

the detection device is positioned on the side of the incubation disc;

the reaction cup loading device, the sample reagent device, the incubation cleaning device, the sampling device, the reaction cup grabbing device and the detection device are all electrically connected with the control system;

the reaction cup loading device, the sample reagent device, the sampling device, the incubation cleaning device, the detection device and the control system are all arranged on the frame.

2. The chemiluminescent immunoassay analyzer of claim 1, wherein: a lifting assembly for pushing the reaction cup to ascend is arranged in the accommodating cavity of the reaction cup loading device, and comprises a lifting plate capable of sliding in the accommodating cavity and a lifting plate driving assembly for driving the lifting plate to move; the side surface of the conveying channel and the side surface of the lifting plate are arranged side by side, one side, close to the conveying channel, of the upper surface of the lifting plate is lower than the other side, so that the reaction cups on the lifting plate can slide into the conveying channel; the conveying channel is obliquely arranged.

3. The chemiluminescent immunoassay analyzer of claim 1, wherein: a lifting assembly for pushing the reaction cup to ascend is arranged in the accommodating cavity of the reaction cup loading device, and comprises a lifting plate capable of sliding in the accommodating cavity and a lifting plate driving assembly for driving the lifting plate to move; the end part of the conveying channel and the end part of the lifting plate are arranged side by side, a groove is formed in the upper surface of the lifting plate, and the height of one end, close to the conveying channel, of the groove is lower than that of the other end of the groove.

4. The chemiluminescent immunoassay analyzer of claim 2 or 3, wherein: the width of the lifting plate is matched with that of the reaction cup.

5. The chemiluminescent immunoassay analyzer of claim 1, wherein: the outer surface of the reaction cup is provided with a cup edge, and the width of the conveying channel is greater than that of the reaction cup and smaller than that of the cup edge; the cup edge divides the reaction cup into two sections, and the weight of one section of the reaction cup close to the bottom is larger than that of the other section.

6. The chemiluminescent immunoassay analyzer of claim 1, wherein: the reaction cup loading device further comprises a first sensor and a second sensor which are used for detecting the reaction cups, the first sensor and the second sensor are both arranged on the conveying channel, the position of the first sensor is higher than that of the second sensor, and the first sensor and the second sensor are both electrically connected with the control system.

7. The chemiluminescent immunoassay analyzer of claim 1, wherein: the bottom of the accommodating cavity is provided with a slot, the bottom of the accommodating cavity is obliquely arranged, the slot is positioned at the lowest position of the bottom of the accommodating cavity, and the lifting plate is arranged at the bottom of the accommodating cavity through the slot; the accommodating cavity is internally provided with a partition board which divides the accommodating cavity into a storage area and a screening area, the upper end of the storage area is provided with an opening for the reaction cup to enter, the lower end of the storage area is communicated with the lower end of the screening area, and the upper end of the conveying channel and the lifting plate are both positioned in the screening area; the outer wall of the accommodating cavity is further provided with a guide plate, the guide plate is provided with a guide groove, the guide plate is arranged above the conveying channel, and an opening of the guide groove is opposite to the conveying channel.

8. The chemiluminescent immunoassay analyzer of claim 1, wherein: the cup feeding part is provided with a cup feeding opening, a placing part for placing a reaction cup, a pushing part sliding between the cup feeding opening and the placing part, and an electromagnet for controlling the movement of the pushing part, the placing part is positioned at the lower end part of the conveying channel, and the electromagnet is electrically connected with a control system.

9. The chemiluminescent immunoassay analyzer of claim 1, wherein: the sample disc and the reagent disc are coaxially arranged, and the sample disc is positioned on the outer ring of the reagent disc; the first driving assembly comprises a sample disc driving assembly for driving the sample disc to rotate and a reagent disc driving assembly for driving the reagent disc to rotate.

10. The chemiluminescent immunoassay analyzer of claim 1, wherein: the incubation disc is arranged on the outer ring of the cleaning disc, or the cleaning disc is arranged on the outer ring of the incubation disc.

Technical Field

The invention relates to a medical instrument, in particular to a chemiluminescence immunoassay analyzer.

Background

With the improvement of living standard and the progress of health consciousness, IVD (in vitro diagnosis) service is more and more integrated into families of people to detect the health condition of people. At present, the demand for automated and integrated instruments with high efficiency, high throughput and high precision is increasing, and chemiluminescence immunoassay is a typical instrument.

The chemiluminescence immunoassay analyzer is an instrument for detecting samples by a chemiluminescence method, and is applied to detection and analysis of various antigens, haptens, antibodies, hormones, enzymes, fatty acids, vitamins and medicines. The specific principle is as follows: the sample is labeled with a luminescent substance, the chemiluminescent substance is catalyzed by a catalyst and oxidized by an oxidant to form an excited intermediate, when the excited intermediate returns to a stable ground state, photons are emitted, and an optical signal measuring instrument receives an optical signal, so that the condition of the labeled substance (such as an antigen or an antibody) in the sample is reflected.

The prior chemiluminescence immunoassay analyzer comprises components such as a reaction cup loading mechanism, a sample unit, a sample separate-injection mechanism, a reagent unit, a reagent separate-injection mechanism, a reaction disc, a uniform mixing mechanism, a measuring unit, a magnetic separation unit, a transfer mechanism and the like, even some instruments comprise more than two magnetic separation units, the structure is complex, and the space required by each component is larger, for example, the transfer mechanism is used for scheduling the reaction cup at least among the reaction cup loading mechanism, the reaction disc, the uniform mixing mechanism and the magnetic separation unit, and larger space is inevitably required in order to ensure that the transfer mechanism moves smoothly in a large range.

In conclusion, the existing chemiluminescence immunoassay analyzer has large volume, complex structure and high product price.

Disclosure of Invention

The invention provides a chemiluminescence immunoassay analyzer, which is used for simplifying the existing structure and reducing the volume of the analyzer.

In order to achieve the purpose, the invention adopts the following specific technical scheme:

a chemiluminescent immunoassay analyzer comprising:

the reaction cup loading device is used for loading a reaction cup and comprises an accommodating cavity, a conveying channel connected with the accommodating cavity and a cup inlet part matched and connected with the lower end of the conveying channel;

the sample reagent device comprises a sample disc for placing a sample, a reagent disc for placing a reagent, and a first driving assembly for driving the sample disc and the reagent disc to rotate;

the incubation cleaning device comprises an incubation disc, a cleaning disc and a second driving assembly, wherein the incubation disc is used for placing the reaction cup and incubating a sample in the reaction cup, the cleaning disc is used for cleaning magnetic particles in the reaction cup, and the second driving assembly is used for driving the incubation disc and the cleaning disc to rotate; the incubation disc and the cleaning disc are both provided with placing positions for placing reaction cups, the incubation disc and the cleaning disc are concentrically arranged, and the incubation disc is positioned below the cup inlet part;

the sampling device comprises a sampling arm, a sampling needle, a sampling driving assembly and a cleaning pool, wherein the sampling needle is arranged on the sampling arm, the sampling driving assembly is used for driving the sampling arm and the sampling needle to move, the cleaning pool is used for cleaning the sampling needle, and the movement track of the sampling needle is intersected with the sample disc, the reagent disc, the incubation disc and the cleaning pool;

the reaction cup grabbing device is used for grabbing and transferring the reaction cups between the incubation disc and the cleaning disc;

the detection device is positioned on the side of the incubation disc;

the reaction cup loading device, the sample reagent device, the incubation cleaning device, the sampling device, the reaction cup grabbing device and the detection device are all electrically connected with the control system;

the reaction cup loading device, the sample reagent device, the sampling device, the incubation cleaning device, the detection device and the control system are all arranged on the frame.

A lifting assembly for pushing the reaction cup to ascend is arranged in the accommodating cavity of the reaction cup loading device, and comprises a lifting plate capable of sliding in the accommodating cavity and a lifting plate driving assembly for driving the lifting plate to move; the side surface of the conveying channel and the side surface of the lifting plate are arranged side by side, one side, close to the conveying channel, of the upper surface of the lifting plate is lower than the other side, so that the reaction cups on the lifting plate can slide into the conveying channel; the conveying channel is obliquely arranged.

A lifting assembly for pushing the reaction cup to ascend is arranged in the accommodating cavity of the reaction cup loading device, and comprises a lifting plate capable of sliding in the accommodating cavity and a lifting plate driving assembly for driving the lifting plate to move; the end part of the conveying channel and the end part of the lifting plate are arranged side by side, a groove is formed in the upper surface of the lifting plate, and the height of one end, close to the conveying channel, of the groove is lower than that of the other end of the groove.

The width of the lifting plate is matched with that of the reaction cup. The term "fit" as used herein means that two or more reaction cups can be placed on the lifting plate, but not simultaneously.

The outer surface of the reaction cup is provided with a cup edge, and the width of the conveying channel is greater than that of the reaction cup and smaller than that of the cup edge; the cup edge divides the reaction cup into two sections, and the weight of one section of the reaction cup close to the bottom is larger than that of the other section.

The reaction cup loading device further comprises a first sensor and a second sensor which are used for detecting the reaction cups, the first sensor and the second sensor are both arranged on the conveying channel, the position of the first sensor is higher than that of the second sensor, and the first sensor and the second sensor are both electrically connected with the control system. The term "for detecting reaction cups" as used herein refers to detecting whether there are reaction cups at the position, and the sensor may be any of various conventional sensors, such as an optical coupling sensor.

The bottom of the accommodating cavity is provided with a slot, the bottom of the accommodating cavity is obliquely arranged, the slot is positioned at the lowest position of the bottom of the accommodating cavity, and the lifting plate is arranged at the bottom of the accommodating cavity through the slot; the accommodating cavity is internally provided with a partition board which divides the accommodating cavity into a storage area and a screening area, the upper end of the storage area is provided with an opening for the reaction cup to enter, the lower end of the storage area is communicated with the lower end of the screening area, and the upper end of the conveying channel and the lifting plate are both positioned in the screening area; the outer wall of the accommodating cavity is further provided with a guide plate, the guide plate is provided with a guide groove, the guide plate is arranged above the conveying channel, and an opening of the guide groove is opposite to the conveying channel.

The cup feeding part is provided with a cup feeding opening, a placing part for placing a reaction cup, a pushing part sliding between the cup feeding opening and the placing part, and an electromagnet for controlling the movement of the pushing part, the placing part is positioned at the lower end part of the conveying channel, and the electromagnet is electrically connected with a control system.

The sample disc and the reagent disc are coaxially arranged, and the sample disc is positioned on the outer ring of the reagent disc; the first driving assembly comprises a sample disc driving assembly for driving the sample disc to rotate and a reagent disc driving assembly for driving the reagent disc to rotate.

The incubation disc is arranged on the outer ring of the cleaning disc, or the cleaning disc is arranged on the outer ring of the incubation disc.

The invention has the beneficial effects that:

firstly, the invention aims to achieve the technical effects of simplifying the structure and reducing the volume of the equipment by improving the structure; mainly embodied in the following aspects: (1) the reagent disc and the sample disc are concentric discs, and the incubation disc and the cleaning disc are concentric discs, so that the volume is reduced; (2) the reaction cups are conveyed to the upper part of the incubation plate by the conveying channel, and the reaction cups directly fall into the incubation plate, so that the problem that the reaction cups are arranged in a specific position by using a hand grip when entering the reaction cups is avoided, and the reaction cups do not need to be sequenced according to the arrangement of the hand grip; in addition, the reaction cup can be directly placed in the containing cavity, so that the reaction cup loading system can be flexibly arranged in space as required; the automatic sequencing device in the prior art needs a large space, and has requirements on the position of the sequencing device due to the fact that the automatic sequencing device needs to be transferred by a hand; (3) the reagent and the sample both adopt a sampling needle, the requirement on space is further reduced, and the cleaning position of the cleaning needle is on the motion track of the cleaning needle so as to be convenient for operation; (4) the reaction cup gripping device only completes the direct transfer between the incubation disc and the cleaning disc, and the space required by the movement is small;

secondly, the reaction cup loading mechanism is provided with the cup edge, and the weight of the reaction cup is utilized in the sequencing process, so that the reaction cup sequencing device can rapidly sequence, and the reaction cup cannot be inverted.

Third, since the present invention has the first sensor and the second sensor, the number of cuvettes in the transfer passage can be controlled within a certain range.

Drawings

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic structural view of a loading device for cuvettes according to the present invention;

FIG. 3 is a schematic view of the interior of the receiving chamber of FIG. 2;

FIG. 4 is a schematic view of the structure of the other state of FIG. 3;

FIG. 5 is a schematic view of the structure in which the partition is installed in the accommodation chamber;

FIG. 6 is a partial cross-sectional view of FIG. 4;

FIG. 7 is a schematic structural view of another embodiment of the reaction cup loading apparatus of the present invention;

FIG. 8 is a schematic view of the structure of the reaction cup;

FIG. 9 is a schematic view of the construction of the cuvette holding means;

fig. 10 is a schematic view of the structure of fig. 9 from another angle.

The reference numbers in the figures denote:

the reaction cup loading device 1, the accommodating chamber 11, the lifting plate 112, the lifting plate driving assembly 114, the slot 115, the partition plate 116, the groove 117, the guide plate 118, the conveying channel 12, the cup entering part 13, the first sensor 14, the second sensor 15 and the reaction cup 16;

sample reagent device 2, sample tray 21, reagent tray 22, first housing 23, sample tray drive assembly 24;

the incubation and cleaning device 3, the second shell 34, the disc cover 35, the via hole 351, the liquid injection blending component 36 and the liquid suction component 37;

the sampling device 4, the sampling driving component 41, the sampling arm 42, the sampling needle 43 and the cleaning pool 44;

the device comprises a reaction cup gripping device 5, a fixed seat 51, a traverse motor 511, a traverse guide rail 512, a traverse belt 513, a traverse plate 52, a lifting motor 521, a lifting guide rail 522, a lifting belt 523, a lifting plate 53, an elastic finger 5, a blending motor 5, a cup-releasing push rod 5 and a cup-releasing motor 534;

a frame 7;

a waste liquid tank 8;

the liquid tank 9 is excited.

Detailed Description

As shown in fig. 1, a chemiluminescent immunoassay analyzer comprises:

the reaction cup loading device 1 is used for loading reaction cups and comprises a containing cavity 11, a conveying channel 12 connected with the containing cavity and a cup entering part 13 connected with the lower end of the conveying channel 12 in a matching way;

the sample reagent device 2 comprises a sample disc 21 for placing a sample, a reagent disc 22 for placing a reagent, and a first driving component for driving the sample disc 21 and the reagent disc 22 to rotate;

the incubation cleaning device 3 comprises an incubation disc, a cleaning disc and a second driving assembly, wherein the incubation disc is used for placing the reaction cup and incubating a sample in the reaction cup, the cleaning disc is used for cleaning magnetic particles in the reaction cup, and the second driving assembly is used for driving the incubation disc and the cleaning disc to rotate; the incubation disc and the cleaning disc are both provided with placing positions for placing reaction cups, the incubation disc and the cleaning disc are concentrically arranged, and the incubation disc is positioned below the cup inlet part 13;

the sampling device 4 comprises a sampling arm 42, a sampling needle 43 arranged on the sampling arm 42, a sampling driving assembly 41 for driving the sampling arm 42 and the sampling needle 43 to move, and a cleaning pool 44 for cleaning the sampling needle, wherein the movement track of the sampling needle 43 is intersected with the sample disc 21, the reagent disc 22, the incubation disc and the cleaning pool 44;

a reaction cup gripping device 5 for gripping and transferring the reaction cup between the incubation tray and the washing tray;

the detection device is positioned on the side of the incubation disc;

the reaction cup loading device 1, the sample reagent device 2, the incubation cleaning device 3, the sampling device 4, the reaction cup grabbing device 5 and the detection device are all electrically connected with the control system;

the device comprises a rack 7, wherein the reaction cup loading device 1, the sample reagent device 2, the sampling device 4, the incubation cleaning device 3, the detection device and the control system are all arranged on the rack 7.

The working process of the invention is as follows:

placing the reaction cups into the accommodating cavity 11, automatically sequencing the reaction cups, directly dropping the reaction cups into the incubation disc through the cup inlet part 13 by the conveying channel 12, and driving the incubation disc to rotate to the next station by the second driving component;

the sampling driving component 41 drives the sampling needle 43 to move, so that a sample and a reagent are sucked in the sample reagent device 2 and added into a reaction cup on an incubation disc for incubation, and before the sample or the reagent is sucked every time, the sampling needle 43 needs to be cleaned in the cleaning pool 44, so that pollution is avoided;

after the incubation is finished, the reaction cup gripping device 5 transfers the reaction cup 16 from the incubation disc to the cleaning disc for cleaning; after cleaning, the reaction cup gripping device 5 transfers the reaction cup 16 from the cleaning disc to the incubation disc, and the detection device is used for detecting the light emitting condition in the reaction cup.

As shown in fig. 2 to 7, the reaction cup loading device has the following specific structure:

the accommodating cavity 11 of the reaction cup loading device 1 is internally provided with a lifting assembly for pushing the reaction cup to ascend, and the lifting assembly comprises a lifting plate 112 capable of sliding in the accommodating cavity 11 and a lifting plate driving assembly 114 for driving the lifting plate 112 to move; the side surface of the conveying channel 12 and the side surface of the lifting plate 112 are arranged side by side, and one side of the upper surface of the lifting plate 112 close to the conveying channel 12 is lower than the other side, so that the reaction cups on the lifting plate 112 can slide into the conveying channel 12; the conveying channel 12 is arranged obliquely; the width of the lifting plate 112 is adapted to the reaction cup. The phrase "the width of the elevating plate 112 is adapted to the reaction cup" as used herein means that the elevating plate 112 can accommodate the reaction cup, but cannot accommodate two or more reaction cups at the same time.

The sequencing process of the reaction cups 16 by the reaction cup loading device 1 is as follows:

the lifting plate driving assembly 114 drives the lifting plate 112 to lift in the accommodating cavity 11, the reaction cups on the upper surface of the lifting plate 112 are pushed by the lifting plate 112 to rise, and when the upper surface of the lifting plate is higher than the upper edge of the conveying channel 12, the reaction cups slide down to the conveying channel 12. In order to ensure that the lifting plate 112 pushes only one reaction cup at a time into the transport channel, the width of the lifting plate is adapted to the reaction cup.

As shown in fig. 8, a cup rim 161 is provided on the outer surface of the reaction cup 16, and the width of the conveying channel 12 is greater than the width of the reaction cup 16 and less than the width of the cup rim 161; the rim 161 divides the reaction cup 16 into two sections, and the weight of one section of the reaction cup 16 near the bottom is greater than that of the other section.

The invention can ensure that the cup opening of the reaction cup 16 is upward: when the reaction cup 16 slides down from the lifting plate 112 to the conveying channel 12, the cup rim 161 is blocked by the upper edge of the conveying channel 12, and the bottom of the reaction cup falls into the conveying channel under the action of gravity, so that the cup opening faces upwards; the cup rim 161 slides along the upper edge of the transfer passage 12, keeping the reaction cup stable. It should be noted that the rim 161 is located at the rim of the reaction cup, i.e. the weight of the reaction cup away from the bottom is zero, which also falls within the protection scope of the present invention.

The reaction cup loading device 1 further comprises a first sensor 14 and a second sensor 15 for detecting the reaction cups, wherein the first sensor 14 and the second sensor 15 are both arranged on the conveying channel 12, the position of the first sensor 14 is higher than that of the second sensor 15, and the first sensor 14 and the second sensor 15 are both electrically connected with the control system. The term "for detecting reaction cups" as used herein refers to detecting whether there are reaction cups at the position, and the sensor may be any of various conventional sensors, such as an optical coupling sensor.

When the first sensor 14 detects that there is a reaction cup, the control system controls the lift plate driving assembly 114 to stop moving, and when the second sensor 15 detects that there is no reaction cup, the control system controls the lift plate driving assembly 114 to start moving, so that the number of reaction cups in the transportation path 12 is controlled within a certain range.

The bottom of the accommodating cavity 11 is provided with a slot 115, the bottom of the accommodating cavity 11 is arranged in an inclined manner, the slot 115 is located at the lowest position of the bottom of the accommodating cavity 11, and the lifting plate 112 is arranged at the bottom of the accommodating cavity 11 through the slot 115; a partition plate 116 is arranged in the accommodating cavity 11, the accommodating cavity 11 is divided into a storage area and a screening area by the partition plate 116, an opening for the reaction cup to enter is formed in the upper end of the storage area, the lower end of the storage area is communicated with the lower end of the screening area, and the upper end of the conveying channel 12 and the lifting plate 112 are both positioned in the screening area; the outer wall of the accommodating cavity is further provided with a guide plate 118, the guide plate is provided with a guide groove, the guide plate is arranged above the conveying channel, and an opening of the guide groove is opposite to the conveying channel.

The lifter plate is located and holds the chamber 11 bottom minimum position to holding the chamber and dividing into storage area and screening area, this kind of structure is favorable to reaction cup 16 to place on the upper surface of lifter plate, can improve the efficiency of sequencing.

The guide plate 118 serves as a guide for the reaction cups when they are moved in the conveyance path 12, and can prevent the reaction cups from sliding out of the conveyance path 12.

The upper end of the receiving chamber 11 is larger than the lower end thereof in order to facilitate the addition of the reaction cup.

The cup feeding part 13 is provided with a cup feeding opening, a placing part for placing reaction cups, a pushing part sliding between the cup feeding opening and the placing part, and an electromagnet for controlling the movement of the pushing part, the placing part is positioned at the lower end part of the conveying channel 12, and the electromagnet is electrically connected with a control system.

Reaction cups on the conveying channel 12 slide to the placing part, and when the reaction cups enter the reaction cups, the pushing part pushes the reaction cups positioned on the placing part to the cup inlet, and the reaction cups fall into the incubation tray from the cup inlet.

The cup inlet portion 13 may have any other conventional structure, and the reaction cup may be dropped onto the incubation plate.

In another embodiment, the internal structure of the reaction cup loading device 1 is as shown in fig. 7, a lifting assembly for pushing the reaction cup to ascend is arranged in the accommodating cavity 11 of the reaction cup loading device 1, and the lifting assembly comprises a lifting plate 112 capable of sliding in the accommodating cavity 11, and a lifting plate driving assembly 114 for driving the lifting plate 112 to move; the end part of the conveying channel 12 and the end part of the lifting plate 112 are arranged side by side, a groove 117 is arranged on the upper surface of the lifting plate 112, and the height of one end, close to the conveying channel 12, of the groove 117 is lower than that of the other end.

The structure of the reagent sample reagent device is as follows:

as shown in fig. 1, the sample tray 21 and the reagent tray 22 are coaxially arranged, and the sample tray is located at the outer ring of the reagent tray; the first drive assembly includes a sample tray drive assembly 24 for driving rotation of the sample tray 21, and a reagent tray drive assembly for driving rotation of the reagent tray 22.

The sample reagent device 2 further comprises a first casing 23, the reagent tray 22 is positioned inside the first casing 23, and a reagent aspirating port is formed in the first casing 23.

The sample tray 21 and the reagent tray 22 are coaxially arranged, and the structure is simple, and the volume occupied by the sample tray 21 and the reagent tray 22 can be reduced.

The incubation and cleaning device has the following structure:

the incubation disc is arranged on the outer ring of the cleaning disc, or the cleaning disc is arranged on the outer ring of the incubation disc, and the two modes have the same principle.

The second drive assembly comprises an incubation drive assembly 2 and a washing drive assembly 3. The incubation driving assembly 2 and the cleaning driving assembly 3 are both motors.

The incubation and washing device 3 further comprises a heating assembly for temperature control of the incubation and washing plates. The heating assembly is positioned below the incubation disc and the cleaning disc and used for heating the incubation disc and the cleaning disc. The heating assembly can maintain the incubation disc and the cleaning disc at the same stable temperature, and heat incubation is carried out on the reaction cup carried by the incubation disc and the cleaning disc.

Incubation cleaning device 3 still includes second shell 34, second shell 34 is fixed in frame 7, second shell 34 is including being located the dish of incubating and wasing the dish lid 35 of dish top, set up on the lid 35 and be used for respectively advancing the cup, advance the appearance, the reaction cup removes, annotate a plurality of via holes 351 of liquid mixing and imbibition.

A liquid injection and mixing component 36 for injecting cleaning liquid and a liquid suction component 37 for sucking the cleaning liquid are arranged above the cleaning disc; and the liquid injection blending assembly 36 and the liquid suction assembly 37 are both arranged on the plate cover 35 and are positioned above the plate cover 35.

Both the homogenizing assembly 36 and the wicking assembly 37 are prior art and will not be described further herein.

The driving mode of the second driving component can be belt driving belt wheels, gear transmission, or the direct connection transmission of a motor shaft and a rotating shaft of the disc body, and the like.

The incubation cleaning device adopts an inner-outer double-disc layout and coaxial driving mode, so that the structure is more compact, the overall volume ratio is smaller, and the overall design of the immunoassay analyzer can be more miniaturized and lightened.

As shown in fig. 9 and 10, the structure of the reaction cup gripping device is as follows:

comprises a fixed seat 51, a traverse moving plate 52 and a lifting plate 53;

the fixed seat 51 is provided with a traverse motor 511, a traverse guide rail 512 and a traverse belt 513 which is in fit connection with an output shaft of the traverse motor through a belt wheel;

the traverse moving plate 52 is provided with a lifting motor 521, a lifting guide rail 522 and a lifting belt 523 which is in fit connection with an output shaft of the lifting motor through a belt wheel;

the lifting plate 53 is provided with an elastic finger 5 positioned below the lifting plate 53, a blending motor 5 for driving the elastic finger 5 to rotate, a hollow cup-releasing push rod 5 penetrating through the elastic finger, and a cup-releasing motor 534 connected with the cup-releasing push rod and used for driving the cup-releasing push rod to move up and down;

the traverse plate 52 is arranged on the traverse guide rail 512 and is in fit connection with the traverse belt 513, and the lifting plate 53 is arranged on the lifting guide rail 522 and is in fit connection with the lifting belt 523.

The cup-removing motor 534 is a linear motor.

The specific structure of the reaction cup gripping device is the prior art, and the details are not repeated here.

The rotation of the traverse motor 511 will drive the traverse belt 513 to rotate, thereby driving the traverse plate 52 to slide on the traverse guide 512, so that the elastic finger 5 moves transversely to the designated station.

The rotation of the lifting motor 521 drives the lifting belt 523 to rotate, so as to drive the lifting plate 53 to slide on the lifting guide rail 522, so that the elastic finger 5 moves up and down, and the reaction cup is grabbed.

The rotation of the blending motor 5 can drive the elastic finger 5 to rotate, and the blending of the liquid in the reaction cup is realized. The cup-removing motor 534 drives the cup-removing push rod 5 to move, so that the reaction cup is ejected out of the elastic finger 5.

As shown in fig. 1, a waste liquid tank 8 for containing waste liquid and an excitation liquid tank 9 for placing an excitation liquid reagent bottle are further mounted on the frame 7.

The invention aims to achieve the technical effects of simplifying the structure and reducing the volume of the equipment by improving the structure; mainly embodied in the following aspects:

1. the reagent disc and the sample disc are concentric discs, and the incubation disc and the cleaning disc are concentric discs;

2. the reaction cups are conveyed to the upper part of the incubation plate by the conveying channel, and the reaction cups directly fall into the incubation plate, so that the problem that the reaction cups are arranged at a specific position by using a hand grip when entering the reaction cups is avoided, and the reaction cups are not required to be arranged according to the arrangement of the hand grip; in addition, the reaction cup can be directly placed in the containing cavity, so that the reaction cup loading system can be flexibly arranged in space as required; the automatic sequencing device in the prior art needs a large space, and has requirements on the position of the sequencing device due to the fact that the automatic sequencing device needs to be transferred by a hand;

3. the reagent and the sample both adopt a sampling needle, the requirement on space is further reduced, and the cleaning position of the cleaning needle is on the motion track of the cleaning needle so as to be convenient for operation;

4. the cuvette holding means only performs a direct transfer between the incubation tray and the washing tray, and the space required for the movement is small.