阅读说明：本技术 一种动物液压损伤造模装置 (Animal hydraulic damage molding device ) 是由 郭衍俊 何雪永 郑楠 徐林 于 2019-10-15 设计创作，主要内容包括：本发明公开了一种动物液压损伤造模装置,包括底座和位于底座顶面的固定板,所述固定板的前端面通过固定座和连接件固定连接有液压管,所述液压管的一端安装有连接板,所述液压管的另一端可拆卸连接有打击管,所述打击管、连接板与液压管对应的一侧均安装有活塞,且两个所述活塞均位于液压管内,两个所述活塞之间填充有生理盐水,且所述液压管上安装有水压传感器；该方法制造的动物模型,受外界因素如动物头颅发育的差异影响小,致伤力定量准确,稳定性和重复性好,致伤量可测定,伤情可分级,可模拟出出较理想的轻、中、重度脑损伤,在峰压3.0atm时可复制出脑干损伤模塑。(The invention discloses an animal hydraulic damage molding device, which comprises a base and a fixed plate positioned on the top surface of the base, wherein the front end surface of the fixed plate is fixedly connected with a hydraulic pipe through a fixed seat and a connecting piece, one end of the hydraulic pipe is provided with a connecting plate, the other end of the hydraulic pipe is detachably connected with a striking pipe, pistons are respectively arranged on the striking pipe, the connecting plate and one side corresponding to the hydraulic pipe, the two pistons are positioned in the hydraulic pipe, physiological saline is filled between the two pistons, and a water pressure sensor is arranged on the hydraulic pipe; the animal model manufactured by the method is slightly influenced by external factors such as differences of animal skull development, the wound capacity is accurate in quantification, the stability and the repeatability are good, the wound capacity can be measured, the wound condition can be graded, ideal light, medium and severe brain injuries can be simulated, and brain stem injury molding can be copied when the peak pressure is 3.0 atm.)

1. The utility model provides an animal hydraulic pressure damage molding device, includes base (1) and fixed plate (2) that are located base (1) top surface, its characterized in that: the front end face of the fixing plate (2) is fixedly connected with a hydraulic pipe (3) through a fixing seat (4) and a connecting piece, one end of the hydraulic pipe (3) is provided with a connecting plate (7), the other end of the hydraulic pipe (3) is detachably connected with a striking pipe (6), pistons (13) are arranged on one sides of the striking pipe (6), the connecting plate (7) and the hydraulic pipe (3) corresponding to each other, the two pistons (13) are located in the hydraulic pipe (3), physiological saline (14) is filled between the two pistons (13), a water pressure sensor (5) is arranged on the hydraulic pipe (3), a support (8) is arranged on the upper end face of the base (1), an arc-shaped guide rail (9) is rotatably connected on the support (8), an impact hammer (12) is arranged on the support (8), and the top of the impact hammer (12) is rotatably connected with the support (8), the striking hammer (12) can swing along an arc-shaped guide rail (9) at a position close to the bottom, and a photoelectric sensor (10) is mounted on the upper end face of the support (8).

2. The animal hydraulic injury molding device according to claim 1, characterized in that: the information recording and displaying device is characterized in that an information recording and displaying mechanism is installed on the base (1), and the information recording and displaying mechanism is composed of a data recording module and a data displaying module.

3. The animal hydraulic injury molding device according to claim 1, characterized in that: the photoelectric sensor (10) is positioned on one side of the joint of the impact hammer (12) and the bracket (8).

4. The animal hydraulic injury molding device according to claim 1, characterized in that: the striking pipe (6) is L-shaped, and the bending part is vertical to the horizontal plane.

5. The animal hydraulic injury molding device according to claim 2, characterized in that: the data recording module can be a data acquisition device, and the data display module can be a display screen.

6. The animal hydraulic injury molding device according to claim 1 or 2, characterized in that: the data recording module, the data display module and the hydraulic pipe (3) are electrically connected, and the data recording module, the data display module and the photoelectric sensor (10) are electrically connected.

Technical Field

The invention belongs to the technical field of experimental instruments, and particularly relates to a hydraulic injury molding device for animals.

Background

The hydraulic impact injury model is one of the most widely used experimental models for traumatic brain injury at present, can be used for researching various aspects of pathology, physiology, pharmacology and the like of the brain injury, and researches related mechanisms of the brain injury on the basis of animal models. Lindgren et al first established a hydraulic impact rabbit craniocerebral injury model. Dixon et al established a hydraulic craniocerebral trauma model of rats, which directly measured the pressure borne by brain tissue with a pressure sensor on a hydraulic impact device, and replicated a light, medium and heavy weight model for relieving craniocerebral trauma.

The influence factors of the success or failure of the mold making are many, the friction between the impact hammer and the bracket, the impact position between the impact hammer and the hydraulic pipe, air bubbles in the hydraulic pipe and the like. When the existing hydraulic impact damage model is used, as no effective means is available for monitoring the molding process, the problem of uncertain accurate injury strength is caused, and therefore the hydraulic damage molding device for the animals is provided.

Disclosure of Invention

The invention aims to provide a hydraulic injury molding device for animals, which aims to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: a hydraulic injury molding device for animals comprises a base and a fixed plate positioned on the top surface of the base, wherein the front end surface of the fixed plate is fixedly connected with a hydraulic pipe through a fixed seat and a connecting piece, one end of the hydraulic pipe is provided with a connecting plate, the other end of the hydraulic pipe is detachably connected with a striking pipe, pistons are arranged on the striking pipe and one side of the connecting plate corresponding to the hydraulic pipe, and the two pistons are both positioned in the hydraulic pipe, and the physiological saline is filled between the two pistons, a hydraulic pressure sensor is arranged on the hydraulic pipe, a bracket is arranged on the upper end surface of the base, an arc-shaped guide rail is rotatably connected on the bracket, and the support is provided with an impact hammer, the top of the impact hammer is rotatably connected with the support, the position of the impact hammer close to the bottom can swing along an arc-shaped guide rail, and the front end face of the support is provided with a photoelectric sensor.

Preferably, the base is provided with an information recording and displaying mechanism, and the information recording and displaying mechanism consists of a data recording module and a data displaying module.

Preferably, the photoelectric sensor is positioned on one side of the joint of the impact hammer and the bracket.

Preferably, the striking pipe is L-shaped, and the bent portion is perpendicular to the horizontal plane.

Preferably, the data recording module may be an information collector, and the data display module may be a display screen.

Preferably, the data recording module, the data display module and the pressure sensor on the hydraulic pipe are electrically connected, and the data recording module, the data display module and the photoelectric sensor are electrically connected.

Compared with the prior art, the invention has the beneficial effects that:

the animal model manufactured by the method has accurate wound-causing capacity quantification, good stability and repeatability, measurable wound amount, small influence by external factors such as differences of animal skull development, gradable wound condition and capability of simulating more ideal light, medium and severe brain injuries.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention.

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view showing the internal structure of the hydraulic pipe according to the present invention;

FIG. 3 is a graphical representation of the impact process of the present invention;

in the figure: 1. a base; 2. a fixing plate; 3. a hydraulic tube; 4. a fixed seat; 5. a water pressure sensor; 6. a striking tube; 7. a connecting plate; 8. a support; 9. an arc-shaped guide rail; 10. a photosensor; 12. an impact hammer; 13. a piston; 14. physiological saline.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "vertical", "upper", "lower", "horizontal", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.

In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly and may, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; either directly or indirectly through intervening media, or through the communication between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

Referring to fig. 1-3, the present invention provides a technical solution: a hydraulic injury molding device for animals comprises a base 1 and a fixing plate 2 positioned on the top surface of the base 1, wherein the front end surface of the fixing plate 2 is fixedly connected with a hydraulic tube 3 through a fixing seat 4 and a connecting piece, a round hole convenient for installing the hydraulic tube 3 is formed in the fixing seat 4, the connecting piece is a screw, a connecting plate 7 is installed at one end of the hydraulic tube 3, a striking tube 6 is detachably connected with the other end of the hydraulic tube 3, the striking tube 6 is L-shaped, the bent part of the striking tube 6 is vertical to the horizontal plane, pistons 13 are installed at one sides of the striking tube 6, the connecting plate 7, corresponding to the hydraulic tube 3, and the two pistons 13 are both positioned in the hydraulic tube 3, normal saline 14 is filled between the two pistons 13, a hydraulic pressure sensor 5 is installed on the hydraulic tube 3, a support 8 is installed on the upper end surface of the base 1, the top of the impact hammer 12 is rotatably connected with the bracket 8, the position of the impact hammer 12 close to the bottom can swing along the arc-shaped guide rail 9, and a photoelectric sensor 10 is arranged on the front end face of the bracket 8.

In this embodiment, preferably, the base 1 is provided with an information recording and displaying mechanism, and the information recording and displaying mechanism is composed of a data recording module and a data displaying module, in this embodiment, the data recording module is an information collector, the data displaying module is a display screen, the data recording module, the data displaying module and the hydraulic pipe 3 are electrically connected, and the data recording module, the data displaying module and the photoelectric sensor 10 are electrically connected.

In the embodiment, it is preferable that the photoelectric sensor 10 is located at one side of the connection part of the striking hammer 12 and the bracket 8, so that the photoelectric sensor 10 can count the number of times of the striking hammer 12 and the connecting plate 7 and record the swing angle of the striking hammer 12.

The working principle and the using process of the invention are as follows: the striking pipe 6 is connected with the hydraulic pipe 3 through a connector, a pressure sensor and a water injection and air exhaust hole are arranged on the striking pipe, a syringe can be arranged on the water injection and air exhaust hole, water and air bubbles are added, the water injection and air exhaust hole is arranged in the middle of the hydraulic pipe 3, the syringe can be arranged on the water injection and air exhaust hole, water and air bubbles are added, the arc-shaped guide rail 9 is provided with scales carved by laser, the scale is 0-90 degrees, the hydraulic pipe 3 is made of organic glass, toughened glass and other materials, the striking pipe 6 is made of stainless steel, aluminum, copper and other materials, and the striking;

when the device is used, the impact hammer 12 is stirred upwards along the arc-shaped guide rail 9, the photoelectric sensor 10 detects the initial swing angle of the impact hammer 12, then the impact hammer 12 is loosened, the impact hammer 12 can swing downwards under the action of gravity and impact the connecting plate 7, after impact, the connecting plate 7 can move to one side of the impact tube 6, the pressure of the physiological saline 14 is increased, the water pressure sensor 5 starts to record the pressure at the moment, the impact tube 6 moves to one side far away from the connecting plate 7, if the animal brain is placed at one side of the impact tube 6, the impact tube 6 and the animal brain can be damaged, meanwhile, the data recording module records the initial swing angle information of the impact hammer 12 detected by the photoelectric sensor 10 and the corresponding pressure information detected by the water pressure sensor 5, and data display is carried out by the data display module, the quantitative accuracy of the injury force can be realized by adjusting the starting swing angle of the impact hammer 12 so as to adjust the pressure on the physiological saline 14, the injury amount can be measured, the injury condition can be graded, the ideal light, medium and heavy brain injuries can be simulated, the brain stem injury molding can be copied when the peak pressure is 3.0atm, the impact process curve can be displayed in real time through an oscilloscope, upper computer software and a liquid crystal display, and the impact force peak value and the impact duration time can be automatically identified through a program.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.