阅读说明：本技术 适用于自动化生产的培养袋 (Culture bag suitable for automated production ) 是由 胡祥 刘沐芸 梁晓 吕新志 于 2018-06-26 设计创作，主要内容包括：本发明公开一种适用于自动化生产的培养袋,包括：上壳,所述上壳的一端形成有盖接部；下壳,所述下壳与上壳围成收纳空间,所述下壳的一端对应上壳的盖接部形成有承接部,所述承接部与盖接部盖接配合且承接部与盖接部之间形成有管道槽,所述管道槽贯穿盖接部和/或承接部；培养袋,所述培养袋位于收纳空间内,且培养袋对应承接部的一端形成有收纳于管道槽内的导引管道,所述导引管道的中间设有挤压部；管道封堵组件,所述管道封堵组件紧压于导引管道的挤压部,以使培养袋内外空间隔离,在管道封堵组件外力时,管道封堵组件与导引管道的挤压部分离,以使培养袋内外空间相通。本发明的技术方案能够方便机器夹取培养袋,有利于实现自动化生产。(The invention discloses a culture bag suitable for automatic production, which comprises: the upper shell, one end of the said upper shell has cover the joint part; the lower shell and the upper shell form a containing space in a surrounding mode, one end of the lower shell is provided with a bearing part corresponding to the covering and connecting part of the upper shell, the bearing part is in covering and matching with the covering and connecting part, a pipeline groove is formed between the bearing part and the covering and connecting part, and the pipeline groove penetrates through the covering and connecting part and/or the bearing part; the culture bag is positioned in the accommodating space, a guide pipeline accommodated in the pipeline groove is formed at one end of the culture bag corresponding to the bearing part, and a squeezing part is arranged in the middle of the guide pipeline; the pipeline plugging component is tightly pressed on the extrusion part of the guide pipeline so as to isolate the inner space and the outer space of the culture bag, and when external force is applied to the pipeline plugging component, the pipeline plugging component is separated from the extrusion part of the guide pipeline so as to communicate the inner space and the outer space of the culture bag. The technical scheme of the invention can facilitate the clamping of the culture bag by a machine, and is beneficial to realizing automatic production.)

1. A culture bag adapted for automated production, comprising:

the upper shell, one end of the said upper shell has cover the joint part;

the lower shell and the upper shell form a containing space in a surrounding mode, one end of the lower shell is provided with a bearing part corresponding to the covering and connecting part of the upper shell, the bearing part is in covering and matching with the covering and connecting part, a pipeline groove is formed between the bearing part and the covering and connecting part, and the pipeline groove penetrates through the covering and connecting part and/or the bearing part;

the culture bag is positioned in the accommodating space, a guide pipeline accommodated in the pipeline groove is formed at one end of the culture bag corresponding to the bearing part, and a squeezing part is arranged in the middle of the guide pipeline;

the pipeline plugging component is tightly pressed on the extrusion part of the guide pipeline so as to isolate the inner space and the outer space of the culture bag, and when external force is applied to the pipeline plugging component, the pipeline plugging component is separated from the extrusion part of the guide pipeline so as to communicate the inner space and the outer space of the culture bag.

2. The culture bag adapted for automated production according to claim 1, wherein the tube blocking member comprises a blocking piece abutting against the pressing portion of the guide tube, and an elastic member abutting against the blocking piece and the lower case at both ends thereof, respectively.

3. The cultivation bag suitable for automatic production as claimed in claim 2, wherein the lower case is provided with a receiving groove for receiving the pipeline plugging assembly, and the receiving groove is vertically intersected with the pipeline groove.

4. The culture bag suitable for automated production according to claim 3, wherein the bottom of the container is provided with at least one fixing pin;

the elastic piece is a spring which is sleeved on the fixing pin.

5. The culture bag suitable for automated production according to claim 4, wherein the lower case is formed at opposite sides thereof with at least one open groove for the robot to grip.

6. The culture bag suitable for automated production according to claim 4, wherein the upper and lower shells are respectively provided with a plurality of strip-shaped grooves.

7. The culture bag suitable for automated production according to claim 1, wherein a first groove is formed on one side of the upper case, and the first groove penetrates through the covering part;

a second groove is formed in one side, in contact with the upper shell, of the lower shell, the second groove penetrates through the bearing part, and the first groove and the second groove form a pipeline groove.

8. The culture bag according to claim 1, wherein the upper shell is bent, and the bent portion of the upper shell is formed with at least one through hole;

the bottom of the culture bag is provided with a positioning hole corresponding to the through hole of the bent part;

at least one positioning column is arranged on one side of the lower shell, which corresponds to the bending part of the upper shell, so that the bottom of the culture bag is clamped between the upper shell and the lower shell when the upper shell and the lower shell are matched.

9. The culture bag suitable for automated production according to claim 8, wherein the upper case and the lower case are fixed by screwing.

10. The culture bag suitable for automated production according to claim 9, wherein a two-dimensional code is provided on any one of the upper shell, the lower shell or the culture bag.

Technical Field

The invention relates to the technical field of cell culture consumables, in particular to a culture bag suitable for automatic production.

Background

With the continuous development of biotechnology, the development of cell culture consumables is also driven by the change of industrialized cell culture technology, and a cell culture bag is one of numerous consumables. At present, the cell culture bag is mostly made of soft plastic or resin, and the whole bag body is relatively soft and is suitable for manual operation. With the requirement of automatic production, manual operation is gradually replaced by machine operation, but in mechanical operation, because the cell culture bag is softer, the cell culture bag is easy to slip when the machine is used for taking goods, the cell culture bag is difficult to clamp, or the cell culture bag is pressed when the machine is used for taking goods, and when the machine is used for taking goods for many times, the bag body of the cell culture bag is easy to damage, even the cell culture bag is punctured, and the service life of the cell culture bag is shortened.

In view of the above, there is a need to provide further improvements to the structure of current cell culture bags.

Disclosure of Invention

In order to solve at least one of the above technical problems, the main object of the present invention is to provide a culture bag suitable for automated production.

In order to achieve the purpose, the invention adopts a technical scheme that: there is provided a culture bag suitable for automated production, comprising:

the upper shell, one end of the said upper shell has cover the joint part;

the lower shell and the upper shell form a containing space in a surrounding mode, one end of the lower shell is provided with a bearing part corresponding to the covering and connecting part of the upper shell, the bearing part is in covering and matching with the covering and connecting part, a pipeline groove is formed between the bearing part and the covering and connecting part, and the pipeline groove penetrates through the covering and connecting part and/or the bearing part;

the culture bag is positioned in the accommodating space, a guide pipeline accommodated in the pipeline groove is formed at one end of the culture bag corresponding to the bearing part, and a squeezing part is arranged in the middle of the guide pipeline;

the pipeline plugging component is tightly pressed on the extrusion part of the guide pipeline so as to isolate the inner space and the outer space of the culture bag, and when external force is applied to the pipeline plugging component, the pipeline plugging component is separated from the extrusion part of the guide pipeline so as to communicate the inner space and the outer space of the culture bag.

Wherein, pipeline shutoff subassembly includes the shutoff piece of the extrusion portion of butt guide pipeline to and the elastic component of both ends butt shutoff piece and inferior valve respectively.

The lower shell is provided with a containing groove for containing the pipeline plugging component, and the containing groove is vertically intersected with the pipeline groove.

At least one fixed pin is arranged at the bottom of the accommodating groove;

the elastic piece is a spring which is sleeved on the fixing pin.

Wherein, the opposite side of inferior valve forms at least an open slot that supplies the arm to press from both sides and get respectively.

Wherein, a plurality of bar-shaped grooves are respectively arranged on the upper shell and the lower shell.

A first groove is formed in one side of the upper shell and penetrates through the covering part;

a second groove is formed in one side, in contact with the upper shell, of the lower shell, the second groove penetrates through the bearing part, and the first groove and the second groove form a pipeline groove.

The upper shell is arranged in a bent shape, and at least one through hole is formed in the bent part of the upper shell;

the bottom of the culture bag is provided with a positioning hole corresponding to the through hole of the bent part;

at least one positioning column is arranged on one side of the lower shell, which corresponds to the bending part of the upper shell, so that the bottom of the culture bag is clamped between the upper shell and the lower shell when the upper shell and the lower shell are matched.

Wherein, the upper shell is fixed with the lower shell by screw joint.

Wherein, be equipped with the two-dimensional code on any one of epitheca, inferior valve or culture bag.

The technical scheme of the invention mainly comprises an upper shell, a lower shell, a culture bag and a pipeline plugging component, wherein the upper shell and the lower shell enclose a containing space for containing the culture bag, so that when the culture bag is clamped, a machine does not need to directly act on the culture bag, the clamping is convenient, the culture bag is not damaged, and the automatic operation of cell culture is favorably realized; when the pipeline plugging assembly is not under the action of external force, the pipeline plugging assembly is directly abutted against and extrudes the extrusion part of the guide pipeline, so that the isolation of the inner space and the outer space of the culture bag is realized, the air pressure in the culture bag is constant, the liquid in the culture bag cannot swing out, and the culture bag is suitable for transportation; when the pipeline plugging component is acted by external force, the internal space and the external space of the culture bag are communicated and are suitable for being injected with cell sap.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the structures shown in the drawings without creative efforts.

FIG. 1 is a schematic perspective view of a culture bag suitable for automated production according to an embodiment of the present invention;

FIG. 2 is an exploded view of a view of FIG. 1;

fig. 3 is an exploded view of fig. 1 from another perspective.

The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

It should be noted that the description of the invention relating to "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying any relative importance or implicit indication of the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.

FIG. 1 is a schematic perspective view of a culture bag suitable for automated production according to an embodiment of the present invention; FIG. 2 is an exploded view of a view of FIG. 1; fig. 3 is an exploded view of another view in fig. 1. In an embodiment of the present invention, the cultivation bag suitable for automated production comprises:

an upper case 10, one end of the upper case 10 is formed with a capping part 11;

a lower shell 20, the lower shell 20 and the upper shell 10 enclosing a receiving space, a receiving portion 27 is formed at one end of the lower shell 20 corresponding to the capping portion 11 of the upper shell 10, the receiving portion 27 is in capping fit with the capping portion 11, and a duct channel is formed between the receiving portion 27 and the capping portion 11, the duct channel penetrates through the capping portion 11 and/or the receiving portion 27;

a culture bag 30, wherein the culture bag 30 is positioned in the accommodating space, a guide pipeline 33 accommodated in the pipeline groove is formed at one end of the culture bag 30 corresponding to the bearing part 27, and a squeezing part 32 is arranged in the middle of the guide pipeline 33;

the pipeline plugging component 40 is tightly pressed on the squeezing part 32 of the guide pipeline 33 to isolate the inner space and the outer space of the culture bag 30, and when the pipeline plugging component 40 is applied with external force, the pipeline plugging component 40 is separated from the squeezing part 32 of the guide pipeline 33, so that the inner space and the outer space of the culture bag 30 are communicated.

In the above embodiment, by arranging the culture bag 30 between the upper shell 10 and the lower shell 20, the shell formed by the hard lower shell 20 and the upper shell 10 is directly clamped by a machine when clamping is performed, so that the culture bag 30 is not damaged, the clamping is convenient, and the automatic operation is convenient to realize. The upper case 10 is substantially plate-shaped, the lower case 20 is substantially formed with a recess at one side, and the upper case 10 and the lower case 20 form a framework. The pipeline plugging component 40 plays a plugging role when the culture bag 30 moves and has no external force, and the problem of liquid leakage cannot occur. When injecting liquid, the pipeline plugging component 40 is extruded, and plugging can be cancelled. Here, the culture bag 30 is provided with at least one spout for easy filling.

After the cell sap is injected into the culture bag 30, the culture bag 30 is fixed in a culture shell, so that the culture bag 30 is converted from the soft characteristic to the hard characteristic, the culture bag 30 is automatically injected with culture substances for culture, and then the automatic production requirements are met according to the automatic operation requirements of grabbing, placing and the like of related robots.

The technical scheme of the invention mainly comprises an upper shell 10, a lower shell 20, a culture bag 30 and a pipeline plugging component 40, wherein the upper shell 10 and the lower shell 20 enclose a containing space for containing the culture bag 30, so that when the culture bag 30 is clamped, a machine does not need to directly act on the culture bag 30, the clamping is convenient, the culture bag 30 cannot be damaged, and the automatic operation of cell culture is favorably realized; when no external force is applied to the pipeline plugging assembly 40, the pipeline plugging assembly directly abuts against and extrudes the extrusion part 32 of the guide pipeline 33, so that the isolation of the inner space and the outer space of the culture bag 30 is realized, the air pressure in the culture bag 30 is constant, the liquid in the culture bag 30 cannot be shaken out, and the pipeline plugging assembly is suitable for transportation; when the pipeline plugging assembly 40 is acted by external force, the internal space and the external space of the culture bag 30 are communicated and are suitable for being injected with cell sap.

Referring to fig. 2 and 3, in one embodiment, the pipe-blocking assembly 40 includes a blocking block 41 abutting against the pressing portion 32 of the guide pipe 33, and an elastic member 42 having two ends abutting against the blocking block 41 and the lower case 20, respectively. The elastic member 42 may be a spring, a pressure spring, etc., and the blocking block 41 may be a strip, and the blocking block 41 is made of a hard material to adapt to a proper extrusion force.

Further, the lower shell 20 is provided with a containing groove 24 for containing the pipeline plugging component 40, and the containing groove 24 is vertically intersected with the pipeline groove. The receiving groove 24 is located below the duct groove, and forms a receiving space after the upper case 10 is covered on the lower case 20, so as to receive the elastic member 42 and the blocking block 41. Specifically, the track grooves are provided along the longitudinal direction of the culture bag 30, and correspond to the direction of the storage tank 24 and the width direction of the culture bag 30. And the depth of the receiving groove 24 is greater than that of the rail groove to form a sufficient receiving space.

Further, at least one fixed pin 25 is arranged at the bottom of the accommodating groove 24;

the elastic member 42 is a spring, and the spring is sleeved on the fixing pin 25. The fixing pin 25 can be replaced by a limit post for the spring to sleeve. Specifically, the number of the fixing pins 25 is two, the number of the springs is also two, and the two springs abut against the blocking block 41 at the same time, so that the blocking block 41 is stressed uniformly. It will be appreciated that the number of fixing pins 25 may also be other numbers.

Further, at least one opening groove 21 for the robot arm to grip is formed at opposite sides of the lower case 20, respectively. The open slot 21 may facilitate mechanical arm gripping. The open slot 21 is a clamping portion with a simple structure, and it can be understood that the open slot 21 may be replaced by other structures, such as a concave portion, a convex portion, etc., without limitation.

Further, a plurality of strip-shaped grooves (14,23) are respectively formed in the upper case 10 and the lower case 20. The design of the strip-shaped grooves (14,23) reduces the weight of the upper and lower cases (10, 20), greatly increasing the air permeability of the culture bag (30) inside.

In a specific embodiment, a first groove is formed on one side of the upper shell 10, and the first groove penetrates through the covering part 11;

a second groove 26 is formed on one side of the lower shell 20, which is in contact with the upper shell 10, the second groove 26 penetrates through the bearing part 27, and the first groove and the second groove 26 form a pipeline groove. Considering that the guide duct 33 needs to pass through between the upper case 10 and the lower case 20, the first groove and the second groove 26 are the most preferable solutions, and the guide duct 33 is fixed by the first groove of the upper case 10 and the second groove 26 of the lower case 20 at the same time, so that a better fixing effect is achieved. Of course, in consideration of the specific thickness of the upper case 10 and the lower case 20, duct grooves may be formed on the upper case 10 or the lower case 20.

In a specific embodiment, the upper shell 10 is bent, and the bent portion 12 of the upper shell 10 is formed with at least one through hole 13;

the bottom of the culture bag 30 is provided with a positioning hole 31 corresponding to the through hole 13 of the bending part 12;

at least one positioning column 22 is disposed on one side of the lower case 20 corresponding to the bending part 12 of the upper case 10, so as to clamp the bottom of the culture bag 30 between the upper case 10 and the lower case 20 when the upper case 10 and the lower case 20 are mated.

In the above embodiment, the upper case 10 is bent, the upper case 10 can be hooked on the lower case 20, and when the upper case 10 is hooked on the lower case 20, the culture bag 30 is clamped between the upper case 10 and the lower case 20, so that the bag bottom of the culture bag 30 is fixed, and the bag opening of the culture bag 30 is fixed between the upper case 10 and the lower case 20, so that the culture bag 30 is more stably fixed and more conveniently clamped, and the culture bag 30 is protected.

Further, the upper case 10 is fixed to the lower case 20 by screwing. The upper shell 10 and the lower shell 20 are provided with stainless steel threaded holes, and the stainless steel threaded holes can be fastened and connected through stainless steel screws. It can be pointed out that other fixing structures can be adopted in the scheme to realize the fixed connection between the two.

Further, any one of the upper case 10, the lower case 20 or the culture bag 30 is provided with a two-dimensional code. The culture bag 30 is marked with the two-dimensional code, so that the two-dimensional code can be clearly seen and can be scanned by a code scanning gun, the management of material information is convenient, the temperature range can be borne to be 0-70 ℃, and the expansion of the use environment of the culture bag 30 is facilitated.

The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all modifications and equivalents of the present invention, which are made by the contents of the present specification and the accompanying drawings, or directly/indirectly applied to other related technical fields, are included in the scope of the present invention.