Kit and reagent dish device

文档序号:1693654 发布日期:2019-12-10 浏览:31次 中文

阅读说明:本技术 一种试剂盒及试剂盘装置 (Kit and reagent dish device ) 是由 陶文 王锐 于 2018-05-30 设计创作,主要内容包括:本发明公开了一种试剂盒及试剂盘装置,该试剂盒包括:试剂盒主体,其可拆卸连接在与该试剂盒主体配套的试剂盘上,包括第一试剂瓶区域和第二试剂容纳区域,该第一试剂瓶区域在第一分度圆上设置有第一试剂瓶装配圆孔,该第二试剂容纳区域在第二分度圆上设置有多个第二试剂容纳腔。通过上述方式,能够简化对待测样品的吸取动作流程。(The invention discloses a kit and a reagent tray device, wherein the kit comprises: the reagent box main body is detachably connected to a reagent disc matched with the reagent box main body and comprises a first reagent bottle area and a second reagent accommodating area, the first reagent bottle area is provided with a first reagent bottle matching round hole on a first graduated circle, and the second reagent accommodating area is provided with a plurality of second reagent accommodating cavities on a second graduated circle. By the mode, the suction action process of the sample to be detected can be simplified.)

1. a kit, comprising:

The reagent box main body is detachably connected to a reagent plate matched with the reagent box main body and comprises a first reagent bottle area and a second reagent containing area, the first reagent bottle area is provided with a first reagent bottle matching round hole on a first graduated circle, and the second reagent containing area is provided with a plurality of second reagent containing cavities on a second graduated circle.

2. The reagent cartridge of claim 1, wherein the reagent cartridge body has a fan shape, the first reagent bottle region is located near a center of the fan shape, and the second reagent bottle region is located away from the center of the fan shape.

3. The reagent cartridge according to claim 1, wherein the number of the second reagent holding chambers is 4.

4. The reagent kit of claim 1, wherein the two sides of the first reagent bottle region are respectively provided with a circular arc concave surface, and when the reagent kit is assembled into the reagent disk, the two circular arc concave surfaces are matched with the convex surfaces of any two adjacent guide pillars for positioning arranged on the reagent disk component.

5. The reagent kit of claim 4, wherein the first reagent bottle region is provided with a ring groove at the bottom of the two arc concave surfaces, and the ring grooves are snapped into ring-shaped protrusions at the bottom of the guide pillars.

6. the reagent kit according to claim 1, wherein the bottom parts of the two sides of the second reagent containing area are respectively provided with a first positioning boundary, when the reagent kit is assembled into the reagent disk, the two first positioning boundaries are matched with the second positioning boundaries of any two adjacent limiting blocks for positioning arranged on the reagent disk assembly.

7. The kit of claim 1, further comprising:

And the kit cover plate is covered on the tops of the second reagent accommodating cavities and is provided with a plurality of corresponding second reagent sampling ports.

8. The kit of claim 7, further comprising: the first reagent bottle of assembly in this first reagent bottle joins in marriage the round hole, and the lid is established the first silica gel cover and a plurality of second silica gel cover of establishing at the opening part in second reagent holding chamber on the bottleneck that first reagent holds the chamber.

9. The kit of claim 1, wherein the second reagent holding area is provided with anti-slip projections on both sides.

10. A reagent disk apparatus comprising a plurality of reagent cartridges as claimed in any one of claims 1 to 9 and a reagent disk for mounting a plurality of the reagent cartridges, wherein the reagent disk is detachably attached to the reagent cartridges.

11. The reagent disk apparatus of claim 10, wherein the reagent disk comprises a reagent cartridge positioning means for holding a plurality of reagent cartridges, the reagent cartridge positioning means being removably attachable to the reagent cartridges.

12. the reagent disk apparatus of claim 10, wherein when the reagent cassette is provided with arc-shaped concave surfaces on both sides of the first reagent bottle region, the reagent disk is provided with a plurality of guide posts for positioning at intervals along the first circumferential direction, and the convex surfaces of any two adjacent guide posts are matched with the two arc-shaped concave surfaces.

13. the reagent disk device of claim 12, wherein when the first reagent bottle region is provided with ring grooves at the bottoms of the two circular arc concave surfaces, the bottoms of the guide pillars are correspondingly provided with annular protrusions, and the ring grooves can be clamped into the annular protrusions.

14. The reagent disk apparatus of claim 10, wherein when the bottom portions of the two sides of the second reagent holding area are respectively provided with a first positioning boundary, the reagent disk is correspondingly provided with a plurality of positioning stoppers at intervals along the second circumferential direction, each stopper has a second positioning boundary, and two first positioning boundaries are matched with the second positioning boundaries of any two adjacent stoppers.

Technical Field

The invention relates to the technical field of medical instruments, in particular to a kit and a reagent tray device.

Background

The medical reagent analyzer is an instrument for detecting and analyzing samples, and can provide important data support for the diagnosis, treatment and prevention processes of diseases.

the existing medical reagent analyzer usually comprises a reagent kit part and a reagent kit tray matched with the reagent kit, the reagent kit usually comprises a plurality of reagent samples to be detected, correspondingly, a sample sucking needle needs to move for a plurality of times along the radial direction to respectively suck the samples in different reagent bottles, and the action flow is complex.

The inventor of the application provides a novel reagent kit and a reagent disk device, which can simplify the action flow of a sample sucking needle.

Disclosure of Invention

The invention mainly solves the technical problem of providing a kit and a reagent tray device, which can simplify the absorption action process of a medical analyzer to a sample to be detected.

In order to solve the technical problems, the invention adopts a technical scheme that: a kit is provided.

Wherein, this kit includes:

The reagent box main body is detachably connected to a reagent plate assembly matched with the reagent box main body and comprises a first reagent bottle area and a second reagent accommodating area, the first reagent bottle area is provided with a first reagent bottle matching round hole on a first graduated circle, and the second reagent accommodating area is provided with a plurality of second reagent accommodating cavities on a second graduated circle.

In order to solve the technical problem, the invention adopts another technical scheme that: a reagent disk apparatus is provided.

Wherein, this reagent dish device includes:

A plurality of said reagent cartridges and a reagent tray for mounting a plurality of said reagent cartridges, said reagent tray being removably attached to said reagent cartridges.

The invention has the beneficial effects that: in contrast to the prior art, the present invention provides that the first reagent bottle region is arranged on the first pitch circle and the second reagent holding region comprising a plurality of the second reagent holding chambers is arranged on the second pitch circle, and that the sampling needle only needs to be moved radially from the first pitch circle to the second pitch circle during sampling. When a plurality of samples to be detected in the second reagent accommodating cavities on the same reference circle are sampled, only the kit main body needs to move circumferentially, so that the motion time sequence of the sampling process can be effectively reduced.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts. Wherein:

FIG. 1 is a schematic diagram of the structure of one embodiment of a kit according to the present invention;

FIG. 2 is a top view of the reagent cartridge of FIG. 1 according to the invention;

FIG. 3 is a schematic diagram of a first embodiment of a reagent bottle of the present invention;

FIG. 4 is a cross-sectional view of the first reagent bottle of FIG. 3;

FIG. 5 is a schematic configuration diagram of one embodiment of a reagent disk apparatus of the present invention;

FIG. 6 is a schematic diagram of the construction of one embodiment of a reagent disk assembly of the present invention;

FIG. 7 is a schematic structural view of an embodiment of the reagent disk of FIG. 6.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

referring to fig. 1 and 2, fig. 1 is a schematic structural diagram of an embodiment of a kit, and fig. 2 is a top view of the kit of fig. 1 according to the present invention, the kit including:

The reagent box main body is detachably connected to a reagent disc matched with the reagent box main body and comprises a first reagent bottle area 100 and a second reagent bottle area 200, wherein the first reagent bottle area 100 is provided with a first reagent bottle matching circular hole 110 on a first graduated circle, and the second reagent bottle area 200 is provided with a plurality of second reagent accommodating cavities 210 on a second graduated circle.

In this embodiment, by arranging the first reagent bottle zone 100 on the first pitch circle and the second reagent holding zone 200 comprising a plurality of the second reagent holding chambers 210 on the second pitch circle, the sampling needle only needs to move radially from the first pitch circle to the second pitch circle during sampling. When a plurality of samples to be detected in the second reagent accommodating cavities on the same reference circle are sampled, only the kit main body needs to move circumferentially, so that the motion time sequence of the sampling process can be effectively reduced.

In one embodiment, the kit further comprises: a first reagent bottle 120 accommodated in the first reagent bottle fitting circular hole 110; the second reagent holding chamber 210 holds a reagent. The first sampling port and the second sampling port are respectively arranged at the positions of the first reference circle and the second reference circle, and the reagent disk matched with the reagent kit main body is rotated, so that the plurality of second reagent bottles are aligned with the second sampling port at the position of the second reference circle for sampling.

further, since the reagent cartridge body has a rectangular or fan-shaped outer shape, in one embodiment, the reagent cartridge body has a fan-shaped outer shape, in which case, the first reagent bottle region 100 is located near the center of the fan-shaped circle, and the second reagent bottle region 200 is located far from the center of the fan-shaped circle. Like this, can make full use of this reagent dish space, be convenient for hold more this reagent boxes on this reagent dish, further improve detection efficiency.

In another embodiment, the number of the second reagent bottle accommodating cavities 210 is multiple, for example, 3, 4, 6, 8, etc., and of course, the number may also be set according to the structure of the detecting apparatus and the needs of the user, which is beneficial to better meet the detection requirements. In one embodiment, the number of the second reagent holding chambers 210 is 4.

In one embodiment, the first reagent bottle area 100 is provided with a circular arc concave surface 130 on each side, and when the reagent kit is assembled into the reagent disk, two circular arc concave surfaces 130 are matched with the convex surfaces of any two adjacent guide pillars for positioning provided on the reagent disk assembly. Because the arc concave surface 130 is matched with the convex surface of the guide post, the reagent kit is clamped between the adjacent guide posts, the reagent kit can be conveniently mounted on the reagent tray, and the operation efficiency is improved.

further, the first reagent bottle area 100 is provided with a ring groove 140 at the bottom of the two arc concave surfaces 130, and the ring groove 140 is snapped into a ring-shaped protrusion at the bottom of the guide pillar. The ring groove 140 is clamped in the annular bulge at the bottom of the guide pillar, so that the reagent kit can be reliably positioned, and the reagent kit is prevented from moving in the circumferential direction in the rotating process.

Furthermore, the bottom of the two sides of the second reagent holding area 200 are respectively provided with a first positioning boundary 230, when the reagent kit is assembled into the reagent disk, two first positioning boundaries 230 are matched with the second positioning boundaries of any two adjacent limiting blocks for positioning arranged on the reagent disk assembly. This stopper sets up in the periphery department of this reagent dish, holds regional 200 through carrying out the block to the second reagent of this reagent box at first locating boundary 230 and avoids this second reagent of this reagent box to hold regional 200 and take place circumferential movement at rotatory process, makes the hybrid process of waiting to examine test agent more reliable, high-efficient.

In this embodiment, the first reagent bottle area 100 and the second reagent holding area 200 of the reagent kit are engaged and limited by the guide post and the limiting block, respectively, so that the reagent bottles can be firmly fixed.

in another embodiment, the kit further comprises: and a reagent cartridge cover 240 covering the top of the reagent containing chambers 210 so that the reagent containing chambers 210 and the reagent cartridge cover 240 are integrated. Specifically, the reagent cartridge cover 240 is fixedly connected to the boundaries of the plurality of second reagent holding chambers 210 by ultrasonic welding.

In one embodiment, the kit further comprises: a plurality of second silica gel covers 250 covering the openings of the second reagent holding cavities 210, and the second silica gel covers 250 are fixed at the openings of the second reagent holding cavities 210 by using a hot melting process. The opening is covered with aluminum foil to seal the second reagent holding chamber 210. Furthermore, a plurality of cross-shaped notches are further formed in the second silica gel sleeve 250, so that a sampling needle can be conveniently inserted, and the volatilization of the reagent can be slowed down.

Further, both sides of the second reagent holding region 200 are provided with anti-slip protrusions 260. The anti-slip protrusions 260 are arranged at the opening of the second reagent holding area 200 close to the second reagent holding cavity 210, so that the friction coefficient can be improved, and the reagent box is prevented from slipping off when an operator grabs and places the reagent box. The number of the nonslip protrusions 260 is plural, and each of the nonslip protrusions 260 has a cylindrical shape.

In another embodiment, referring to fig. 1, fig. 3 and fig. 4, fig. 3 is a schematic structural diagram of an embodiment of a first reagent bottle in the present invention, fig. 4 is a cross-sectional view of the first reagent bottle in fig. 3, the first reagent bottle 120 includes a first reagent bottle body 211, and a first reagent bottle mouth 122 and a first reagent bottle bottom 123 respectively disposed at two ends of the first reagent bottle body 121; the outer diameter of the first reagent bottle opening 122 is larger than the inner diameter of the first reagent bottle receiving cavity 110, so that the first reagent bottle 120 can be conveniently placed and taken out. Further, the first reagent bottle 120 is a fluorescent reagent bottle, at least one rib 124 is arranged in the first reagent bottle 120, and the rib 124 is arranged on the first reagent bottle body 121 and has the same extending direction as the first reagent bottle body 121, so that in the process that the sample to be detected in the first reagent bottle 120 rotates along with the first reagent bottle 120, the turbulence of the sample to be detected is promoted, and the mixing uniformity of the sample to be detected is improved.

Furthermore, the first reagent bottle 120 further includes a first silicone sleeve 150 covering the opening of the first reagent bottle, the first silicone sleeve 150 is fixed on the opening of the first reagent bottle by using a hot melting process, and the opening is covered with aluminum foil to seal the first reagent bottle 120. Furthermore, the first silicone sleeve 150 is provided with a cross-shaped notch, so that the insertion of a sampling needle is facilitated, and the volatilization of the reagent can be slowed down.

In another embodiment, the reagent disk and the reagent kit are driven by a motor to rotate during the use of the reagent kit. The first reagent bottle bottom 123 is provided with a transmission member 125 for receiving power from the driven gear on the reagent tray and driving the first reagent bottle 120 to rotate. Therefore, the reagent kit revolves along with the reagent disk and also rotates to form a planetary gear train structure, so that the reagent kit and a sample to be detected in the reagent kit are mixed more uniformly, and the accuracy of a detection result is improved.

In order to solve the technical problem, the invention adopts another technical scheme that: a reagent disk apparatus is provided.

referring to fig. 5 and 6, fig. 5 is a schematic structural view of an embodiment of a reagent disk apparatus of the present invention, and fig. 6 is a schematic structural view of an embodiment of a reagent disk assembly of the present invention, wherein the reagent disk apparatus includes:

A plurality of said reagent cartridges 10 and a reagent tray 20 for mounting a plurality of said reagent cartridges 10, said reagent tray 20 being detachably connected to said reagent cartridges 10. Further, the reagent tray 20 includes a plurality of reagent cartridge positioning devices (not shown) detachably connected to the reagent cartridges 10 for fixing a plurality of the reagent cartridges 10. Further, the reagent disk assembly of fig. 5 includes the reagent disk 20 and one of the reagent cartridges 10 mounted on the reagent disk 20.

in one embodiment, referring to fig. 7, fig. 7 is a schematic structural diagram of an embodiment of the reagent disk in fig. 6, the reagent disk 20 further includes a fixed motor (not shown) and a fixed gear 21 disposed at a central position of the reagent disk, and the reagent cassette positioning device includes: a guide post 22 fixedly provided on the outer periphery of the fixed gear 21; a driven gear 23 disposed between adjacent guide posts 22 and engaged with the fixed gear 21; and a stopper 24 provided at the outer periphery of the reagent disk 20 and corresponding to the guide post 22. Further, the motor drives the reagent disk 20 to rotate, and the fixed gear 21 does not move. The driven gear 23 revolves and moves relative to the fixed gear 21, so as to drive the transmission member 125 of the first reagent bottle bottom 123, and the first reagent bottle 120 rotates.

In one embodiment, with continuing reference to fig. 7, when the reagent container has arc concave surfaces 130 on two sides of the first reagent bottle area 100, the reagent container is provided with a plurality of guide pillars 22 for positioning at intervals along the first circumferential direction, and the convex surfaces of any two adjacent guide pillars 22 are matched with two arc concave surfaces 130; the guide post 22 includes a cylindrical sub-component 221 fixedly connected to the test tray and a tapered sub-component 222 disposed on the cylindrical sub-component 221. The end of the conical sub-member 222 remote from the cylindrical sub-member 221 is pointed to facilitate insertion of the cartridge.

Further, when the first reagent bottle area 100 is provided with the ring grooves 140 at the bottoms of the two arc-shaped concave surfaces 130, the bottoms of the guide pillars 22 are correspondingly provided with the annular protrusions 223, and the ring grooves 140 can be clamped into the annular protrusions 223; the ring groove 120 is engaged with the ring-shaped protrusion 223 at the bottom of the guide post 22, so that the reagent cartridge can be reliably positioned, and the reagent cartridge is prevented from moving in the circumferential direction in the rotating process.

Furthermore, when the bottom of the two sides of the second reagent holding area 200 are respectively provided with the first positioning boundaries 230, the reagent tray is correspondingly provided with a plurality of positioning limiting blocks 24 at intervals along the second circumferential direction, each limiting block 24 is provided with a second positioning boundary (not shown), and two first positioning boundaries 230 are matched with the second positioning boundaries of any two adjacent limiting blocks 24. This stopper 24 sets up in the periphery department of this reagent dish, carries out the block to this second reagent of this reagent box and holds regional 200 and avoid this second reagent of this reagent box to hold regional 200 and take place circumferential movement at the rotation process at first locating boundary 230, makes the hybrid process of waiting to examine test agent more reliable, high-efficient.

In the present embodiment, the first reagent bottle region 100 and the second reagent holding region 200 of the reagent cartridge are engaged and limited by the guide column 22 and the stopper 24, respectively, so that the reagent cartridge can be firmly fixed.

In addition, the kit and the reagent disk device disclosed by the invention are used for a medical reagent analyzer, in particular a chemiluminescence analyzer, and further the chemiluminescence analyzer is a chemiluminescence immunoassay analyzer.

In summary, the present invention discloses a reagent kit and a reagent tray device, wherein the reagent kit comprises: the reagent box main body is detachably connected to a reagent plate assembly matched with the reagent box main body and comprises a first reagent bottle area and a second reagent accommodating area, wherein the first reagent bottle area is provided with a first reagent bottle matching round hole on a first graduated circle, and the second reagent accommodating area is provided with a plurality of second reagent accommodating cavities on a second graduated circle. Through the mode, the medical analyzer can simplify the absorption action process of the medical analyzer on the sample to be detected.

The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes performed by the present specification and drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

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