Chlorine-containing disinfectant and preparation method thereof

文档序号:1723154 发布日期:2019-12-20 浏览:32次 中文

阅读说明:本技术 一种含氯消毒液及制备方法 (Chlorine-containing disinfectant and preparation method thereof ) 是由 仇曼茜 于 2019-08-22 设计创作,主要内容包括:本发明公开了一种含氯消毒液及制备方法,其包括以下原料:对氯间二甲苯酚PCMX 1.5-3%、聚六亚甲基胍2.8-6%、表面活性剂1-2.2%、稳定剂1.2-2.8%、助剂2-4%、余下成分为去离子水;制备步骤包括:先将助剂和对氯间二甲苯酚PCMX加入容器中,在室温下搅拌混合均匀,制得混合液A;然后向上述所得的混合液A中加入表面活性剂、稳定剂和去离子水,升温至30-38℃搅拌混合均匀,制得混合液B;最后向混合液B中加入聚六亚甲基胍,搅拌混合均匀,冷却至室温,灌装制得含氯消毒液。本发明的消毒液采用无毒或低毒的原料,其对环境和人体安全友好环保,且具有见效快、广谱高效、低毒乃至无毒等优势。(The invention discloses a chlorine-containing disinfectant and a preparation method thereof, wherein the chlorine-containing disinfectant comprises the following raw materials: 1.5-3% of parachlorometaxylenol PCMX, 2.8-6% of polyhexamethylene guanidine, 1-2.2% of surfactant, 1.2-2.8% of stabilizer, 2-4% of auxiliary agent and the balance of deionized water; the preparation method comprises the following steps: adding the auxiliary agent and parachlorometaxylenol PCMX into a container, and stirring and mixing uniformly at room temperature to prepare a mixed solution A; then adding a surfactant, a stabilizer and deionized water into the obtained mixed solution A, heating to 30-38 ℃, and uniformly stirring and mixing to obtain mixed solution B; and finally, adding polyhexamethylene guanidine into the mixed solution B, stirring and mixing uniformly, cooling to room temperature, and filling to obtain the chlorine-containing disinfectant. The disinfectant disclosed by the invention adopts nontoxic or low-toxicity raw materials, is safe, environment-friendly and environment-friendly to the environment and human bodies, and has the advantages of quick response, broad spectrum, high efficiency, low toxicity, no toxicity and the like.)

1. The chlorine-containing disinfectant is characterized by comprising the following preparation raw materials in parts by mass: 1.5-3% of parachlorometaxylenol PCMX, 2.8-6% of polyhexamethylene guanidine, 1-2.2% of surfactant, 1.2-2.8% of stabilizer, 2-4% of assistant and the balance of deionized water.

2. The chlorine-containing disinfection solution as claimed in claim 1, wherein the mass ratio of the parachlorometaxylenol PCMX to the polyhexamethylene guanidine is 1: (1-4).

3. The chlorine-containing disinfection solution of claim 1, wherein the surfactant is an amphoteric surfactant.

4. The chlorine-containing disinfection solution as claimed in claim 1, wherein the stabilizing agent is polyethylene glycol and guar gum, and the mass ratio of polyethylene glycol to guar gum is (0.8-2.4): 1.

5. the chlorine-containing disinfection solution as claimed in claim 1, wherein the auxiliary agent is an 80 vol% ethanol solution.

6. The method for preparing chlorine-containing disinfection solution as claimed in any one of claims 1-5, comprising the following steps:

(1) adding the auxiliary agent and parachlorometaxylenol PCMX into a container according to the formula amount, and stirring and mixing uniformly at room temperature to prepare a mixed solution A;

(2) adding a surfactant, a stabilizer and deionized water in a formula amount into the mixed solution A obtained in the step (1), heating to 30-38 ℃, and uniformly stirring and mixing to obtain mixed solution B;

(3) adding the polyhexamethylene guanidine with the formula amount into the mixed solution B, stirring and mixing uniformly, cooling to room temperature, and filling to obtain the chlorine-containing disinfectant.

Technical Field

The invention relates to the technical field of disinfectant, in particular to chlorine-containing disinfectant and a preparation method thereof.

Background

Nosocomial infections refer to infections acquired within a medical facility. Including patients, medical staff, patients accompanying and visitors, all infections acquired in hospitals are nosocomial infections. In our country, however, this refers in particular to infections acquired by the patient during hospitalization. Hospital infection is a serious threat to the life and health of patients and also an important factor affecting the quality of medical treatment. The best way to deal with nosocomial infections is to take a good prescription for disinfection and sterilization, including medical equipment, ward environment, various articles, and the like. It has been demonstrated that the incidence of nosocomial infections can be greatly reduced by simply grasping the device for sterilization.

The disinfection solution in the current market generally contains chlorine components, and is generally divided into inorganic chlorine disinfection solution and organic chlorine disinfection solution, but the inorganic chlorine is unstable in property, is easily influenced by light, heat and humidity, loses effective components, and the organic chlorine is relatively stable, but is generally unstable after being dissolved in water. Therefore, in view of the above problems, an object of the present invention is to provide a chlorine-containing disinfectant that can stably exist in an aqueous solution, is stable in storage of the aqueous solution, has good stability and bactericidal effect, is safe, nontoxic or low-toxic, and can be widely popularized and applied, and a preparation method thereof.

Disclosure of Invention

In view of the above, the present invention aims to provide a disinfectant and a preparation method thereof, which can stably exist organic chlorine in an aqueous solution and achieve more efficient sterilization performance by improving components.

In order to achieve the purpose, the invention adopts the technical scheme that: a chlorine-containing disinfection solution comprises the following preparation raw materials in parts by mass: 1.5-3% of parachlorometaxylenol PCMX, 2.8-6% of polyhexamethylene guanidine, 1-2.2% of surfactant, 1.2-2.8% of stabilizer, 2-4% of assistant and the balance of deionized water.

The mass ratio of the parachlorometaxylenol PCMX to the polyhexamethylene guanidine is 1: (1-4), the reasonable compounding of the parachlorometaxylenol PCMX and the polyhexamethylene guanidine enhances the disinfection effect.

The surfactant is an amphoteric surfactant.

The stabilizing agent is polyethylene glycol and guar gum, wherein the mass ratio of the polyethylene glycol to the guar gum is (0.8-2.4): 1, the stabilizer not only enhances the stability of the organic chlorine in the aqueous solution, but also has the function of water retention and dispersion, so that hydrogen bonds are easily formed with water and the molecules are connected with each other.

The auxiliary agent is an ethanol solution with the volume fraction of 80%.

The preparation method of the chlorine-containing disinfectant comprises the following steps:

(1) adding the auxiliary agent and parachlorometaxylenol PCMX into a container according to the formula amount, and stirring and mixing uniformly at room temperature to prepare a mixed solution A;

(2) adding a surfactant, a stabilizer and deionized water in a formula amount into the mixed solution A obtained in the step (1), heating to 30-38 ℃, and uniformly stirring and mixing to obtain mixed solution B;

(3) adding the polyhexamethylene guanidine with the formula amount into the mixed solution B, stirring and mixing uniformly, cooling to room temperature, and filling to obtain the chlorine-containing disinfectant.

The invention adopts the ethanol solution with the volume fraction of 80% as the auxiliary agent, on one hand, the ethanol solution with the volume fraction of 80% is used for promoting the effective dissolution of the parachlorometaxylenol PCMX, on the other hand, the ethanol solution with the volume fraction of 80% has better sterilization effect, and the sterilization effect is further enhanced after the ethanol solution is mixed with the parachlorometaxylenol PCMX.

The invention has the beneficial effects that: the disinfectant disclosed by the invention adopts nontoxic or low-toxicity raw materials, is safe, environment-friendly and environment-friendly to the environment and human bodies, and has the advantages of quick response, broad spectrum, high efficiency, low toxicity, no toxicity and the like.

Detailed Description

The present invention will be described in detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. These are all within the scope of the present invention (all of the starting components may be commercially available products well known to those skilled in the art).

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