阅读说明：本技术 治疗滑膜炎的药物及其制备方法 (The drug and preparation method thereof for treating synovitis ) 是由 孔祥鹏 于 2019-09-30 设计创作，主要内容包括：本发明公开了一种治疗滑膜炎的药物及其制备方法,制备所述药物的原料包括白芥子、葶苈子和辅料；所述辅料包括轻粉、蜂蜡、白米醋和油脂性基质；制备所述药物的方法包括步骤：(1)将白芥子、葶苈子和其他药材粉碎混合,加入白米醋调匀,备用；(2)将油脂性基质加热至沸腾,加入步骤(1)中得到的物质,继续加热至溶液呈红黄色,加入蜂蜡混匀,冷却；(3)加入轻粉,搅拌均匀即得所述治疗滑膜炎的药物。本发明的治疗滑膜炎的药物具有温经活络、祛风除湿、行水消肿、活血止痛的作用,所选材料易得,制备方法简单,制备的中药药膏直接涂抹于关节患病处,使得膏药的有效成分能直接被皮肤吸收,对治疗滑膜炎具有显著的功效。(The invention discloses a kind of drugs and preparation method thereof for treating synovitis, and the raw material for preparing the drug includes semen brassicae, lepidium seed and auxiliary material；The auxiliary material includes calomel mercurous chloride, beeswax, white rice vinegar and oleaginous base；The method of the drug is prepared comprising steps of (1) mixes semen brassicae, lepidium seed and other pulverizing medicinal materials, addition white rice vinegar is mixed well, spare；(2) oleaginous base is heated to boiling, substance obtained in step (1) is added, continued to be heated to solution in reddish yellow, beeswax is added and mixes, it is cooling；(3) calomel mercurous chloride is added, stirs evenly up to the drug of the treatment synovitis.The drug for the treatment of synovitis of the invention has the function of promoting flow of qi by warming channel, dispelling wind and eliminating dampness, line water detumescence, promoting blood circulation and stopping pain, selected materials are easy to get, preparation method is simple, the Chinese medicine ointment of preparation is applied directly to joint site of disease, cream the effective elements of the medicine is directly absorbed by the skin, there is significant effect to treatment synovitis.)

1. a kind of drug for treating synovitis, which is characterized in that the raw material for preparing the drug includes semen brassicae, lepidium seed and auxiliary Material；The auxiliary material includes calomel mercurous chloride, beeswax, white rice vinegar and oleaginous base.

2. drug according to claim 1, which is characterized in that the oleaginous base is animal oil, vegetable oil, hydrogenation plant The mixture of one or more of object oil, lanolin, insect wax, spermaceti.

3. drug according to claim 1, which is characterized in that the oleaginous base is butter, prepares the drug Raw material includes following parts by weight of component:

4. drug according to claim 3, which is characterized in that the raw material for preparing the drug includes following parts by weight group Point: 60 parts of semen brassicae, 60 parts of lepidium seed, 6 parts of calomel mercurous chloride, 50 parts of beeswax, 200 parts of white rice vinegar, 400 parts of butter.

5. drug according to any one of claims 1-4, which is characterized in that prepare the drug raw material further include as Lower parts by weight of component: 25-40 parts of Radix Notoginseng, 15-30 parts of cape jasmine.

6. drug according to claim 5, which is characterized in that the raw material for preparing the drug includes following parts by weight group Point: 70 parts of semen brassicae, 70 parts of lepidium seed, 8 parts of calomel mercurous chloride, 55 parts of beeswax, 220 parts of vinegar, 450 parts of butter, 30 parts of Radix Notoginseng, cape jasmine 20 Part.

7. the preparation method of drug described in claim 1-6, which is characterized in that comprising steps of

(1) semen brassicae, lepidium seed and other pulverizing medicinal materials are mixed, white rice vinegar is added and mixes well, it is spare；

(2) oleaginous base is heated to boiling, substance obtained in step (1) is added, continue to be heated to solution to be in reddish yellow, Beeswax is added, stirs evenly, it is cooling；

(3) calomel mercurous chloride is added, stirs evenly up to the drug of the treatment synovitis.

8. preparation method according to claim 8, which is characterized in that be added white rice vinegar in step (1) treated system Lipophilic solvent is added to extract, extracting solution is concentrated into after paste, lipophilic solvent processing is added.

9. preparation method according to claim 8, which is characterized in that the granularity of smashed medicinal material is 10-24 mesh.

10. application of the drug as claimed in any one of claims 1 to 6 in the external drug of preparation treatment synovitis.

Technical field

The invention belongs to the field of Chinese medicines, and in particular to a kind of drug and preparation method thereof for treating synovitis.

Background technique

For the site of pathological change of synovitis mainly in knee joint, knee joint is that most human body synovial membrane, articular surface and structure are most complicated Joint, the shallower position of limbs table extensively and is located at due to knee joint synovial membrane, therefore the chance damaged and infected is more.Knee closes Section synovitis is primarily due to syndrome caused by sprain of knee joint and a variety of intraarticular damages.Synovitis be easy to cause patient temporary When or long term portion disability, no matter to patient and to society harm it is all larger.

The method of Modern medical therapy arthritis is broadly divided into drug therapy and operative treatment.General use takes orally non-steroid The treatment of body antiinflammatory drugs, but drug cannot go directly affected part when oral drug therapy, drug effect is slow and ideal effect is not achieved Fruit.And it takes anti-inflammatory drug for a long time and organ is caused to damage.Although and such as drawing liquid, flushing treatment method obtain one Satisfied curative effect a bit, but treatment is not thorough, and is damaged to knee joint.In recent decades, tcm syndrome differentiation and treatment knee closes Section synovitis makes great progress, and with traditional Chinese medical theory to the clinical manifestation dialectical analysis of gonarthromeningitis, proposes Warming yang for dispelling cold, clearing heat and promoting diuresis, the treatment methods such as activating microcirculation and removing stasis medicinal, and achieve good curative effect.

Patent application 2017107967033 discloses a kind of plaster for treating synovitis, plaster using Semen Strychni as monarch drug in a prescription, Toad Skin and kaempferia galamga are ministerial drug, and cape jasmine, the raw root of gansui, asafoetide and lactogenesis perfume (or spice) are adjutant, and Radix Angelicae Sinensis etc. is to make medicine.Plaster arc ingredient seeps Transdermal undertissue goes directly lesion, stimulates nerve endings, promotes qi-blood circulating, and eliminate hydrops, diminishes inflammation.

Summary of the invention

For the defects in the prior art, the present invention provides a kind of drug of external application that can effectively treat synovitis.

The present invention also provides a kind of methods for preparing said medicine.

To solve the above-mentioned problems, present invention employs the following technical solutions；

A kind of drug for treating synovitis, the raw material for preparing the drug includes semen brassicae, lepidium seed and auxiliary material；It is described auxiliary Material includes calomel mercurous chloride, beeswax, white rice vinegar and oleaginous base.

Preferably, the oleaginous base is animal oil, in vegetable oil, hydrogenated vegetable oil, lanolin, insect wax, spermaceti One or more kinds of mixtures.

Semen brassicae: warm lung slit phlegm benefit gas, dissipating bind are removed obstruction in channels to relieve pain；For phlegm asthma cough of trembling with fear, distending pain in the chest and hypochondrium, the stagnant channels and collaterals of phlegm, joint Numb, pain, phlegm-damp oozing in the body, negative subcutaneous ulcer pyogenic infections；Select the dry mature seed of biennial plant sinapsis alba Sinapis alba L.；

Lepidium seed: removing heat from lung and relieving asthma, line water detumescence.It is pungent, bitter, Great Cold, lepidium seed seed (sinapic acid) containing sinapic acid, Strophan- thidins (strophanthidin), yellowish-white erysimoside (helveticoside), evomonoside (evomonoside), Winged euonymus disaccharide glucoside (evobioside), glucose erysimoside (erysimo-side), sinapine (sinapine).

Preferably, the oleaginous base is butter, and the raw material for preparing the drug includes following parts by weight of component:

Preferably, the raw material for preparing the drug includes following parts by weight of component:

Further, the raw material for preparing the drug includes following parts by weight of component: 60 parts of semen brassicae, 60 parts of lepidium seed, 6 parts of calomel mercurous chloride, 50 parts of beeswax, 200 parts of white rice vinegar, 400 parts of butter.

Further, the raw material for preparing the drug further includes following parts by weight of component: 25-40 parts of Radix Notoginseng, cape jasmine 15-30 Part.

It is particularly preferred that the raw material for preparing the drug includes following parts by weight of component: 70 parts of semen brassicae, lepidium seed 70 Part, 8 parts of calomel mercurous chloride, 55 parts of beeswax, 220 parts of white rice vinegar, 450 parts of butter, 30 parts of Radix Notoginseng, 20 parts of cape jasmine.

A kind of preparation method of above-mentioned drug, comprising steps of

(1) semen brassicae, lepidium seed and other pulverizing medicinal materials are mixed, white rice vinegar is added and mixes well, it is spare；

(2) oleaginous base is heated to boiling, substance obtained in step (1) is added, continue to be heated to solution in red Yellow is added beeswax, stirs evenly, cooling；

(3) calomel mercurous chloride is added, stirs evenly up to the drug of the treatment synovitis.

It is added white rice vinegar in step (1) treated system lipophilic solvent is added and extract, extracting solution is concentrated into paste Lipophilic solvent processing is added afterwards.

Preferably, the granularity of smashed medicinal material is 10-24 mesh.

If semen brassicae and lepidium seed are extracted without lipophilic solvent, the system after beeswax is added is filtered after processing again Calomel mercurous chloride is added to mix.

Application of the above-mentioned drug in the external drug of preparation treatment synovitis.The external drug can be emplastrum Or ointment, it is contacted on non-woven fabrics with disease sites by smearing or being applied to.

The beneficial effects of the present invention are embodied in:

The drug for the treatment of synovitis of the invention have promoting flow of qi by warming channel, dispelling wind and eliminating dampness, line water detumescence, promoting blood circulation and stopping pain work With, selected materials are easy to get, and preparation method is simple, and semen brassicae and lepidium seed are first handled through white rice vinegar, there is promoting blood circulation, line water detumescence, And enhancing the effect of analgesic effect, the Chinese medicine ointment that plaster substrate preparation is then added is applied directly to joint site of disease, plaster Effective component can directly by skin absorb, to treatment synovitis have significant effect.

Specific embodiment

The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer Ground illustrates technical solution of the present invention, therefore is only used as example, and not intended to limit the protection scope of the present invention.

It should be noted that unless otherwise indicated, technical term or scientific term used in this application should be this hair The ordinary meaning that bright one of ordinary skill in the art are understood.