阅读说明：本技术 一种清洗奶垢、污渍的清洗消毒片及其制备方法 (A kind of cleaning milk dirt, cleaning and sterilizing piece of spot and preparation method thereof ) 是由 阎昭良 于 2019-08-26 设计创作，主要内容包括：本发明涉及一种清洗奶垢污渍的清洗消毒片。包括有以下按重量份的配比原料：碳酸钠5-35份、酒石酸5-30份。元明粉5-40份、零水偏硅酸钠0.5-25份。氨基磺酸5-30份、氯化钠1-5份。聚乙二醇粉5-20份、硬脂酸镁0.1-3份。阴离子表面活性剂0.5-15份。聚六亚甲基胍盐0.01-8份、过碳酸钠0.5-5份。乙二胺四乙酸二钠0.1-5份。聚乙烯吡咯烷酮0.5-5份。蛋白酶0.1-5份、胞壁质酶0.1-5份。本发明所述消毒片溶解速度快,清洗奶垢、污渍效果好。在极低的浓度下,对大肠杆菌、白色念珠菌杀菌率、淋球菌杀菌率为100％。现场杀菌试验对物体表面杀菌率为99.8％。对没有细胞壁的人体细胞不会产生不利影响。可防止婴幼儿用品微生物污染而引起的酪酸发酵,减少奶腥异味。对人体完全无毒、无副作用,兼有抗病毒的功效。(The present invention relates to a kind of cleaning and sterilizing pieces for cleaning milk dirt spot.It include following proportion raw material by weight: 5-35 parts of sodium carbonate, 5-30 parts of tartaric acid.5-40 parts of anhydrous sodium sulphate, 0.5-25 parts of zero water sodium metasilicate.5-30 parts of sulfamic acid, 1-5 parts of sodium chloride.5-20 parts of polyethylene glycol powder, 0.1-3 parts of magnesium stearate.0.5-15 parts of anionic surfactant.0.01-8 parts of poly (hexamethylene), 0.5-5 parts of SODIUM PERCARBONATE.0.1-5 parts of disodium ethylene diamine tetraacetate.0.5-5 parts of polyvinylpyrrolidone..1-5 parts of proteinase-10,0.1-5 parts of muramidase.Disinfection tablet solution rate of the present invention is fast, and cleaning milk dirt, spot effect are good.It is 100% to Escherichia coli, Candida albicans sterilizing rate, gonococcal bactericidal rate under extremely low concentration.Live sterilization test is 99.8% to body surface sterilizing rate.Will not have an adverse effect to the human body cell of not cell wall.It can prevent butyric acid caused by infant article microbial contamination from fermenting, reduce milk off-flavors.To human body totally nontoxic, without side-effects, antiviral effect is had concurrently.)

1. the cleaning and sterilizing piece of a kind of cleaning milk dirt, spot, it is characterised in that include following proportion raw material by weight:

PH value adjustment agent: 5-35 parts of sodium carbonate, 5-30 parts of tartaric acid；

Filler: 5-40 parts of anhydrous sodium sulphate, 0.5-25 parts of zero water sodium metasilicate；

Chlorinating agent: 5-30 parts of sulfamic acid, 1-5 parts of sodium chloride；

Lubricant: 5-20 parts of polyethylene glycol powder, 0.1-3 parts of magnesium stearate；

Emulsifier: 0.5-15 parts of anionic surfactant；

Disinfectant: 0.01-8 parts of poly (hexamethylene), 0.5-5 parts of SODIUM PERCARBONATE；

Hard water resistance dose: 0.1-5 parts of disodium ethylene diamine tetraacetate；

Granulation binders: 0.5-5 parts of polyvinylpyrrolidone；

Enzyme preparation: .1-5 parts of proteinase-10,0.1-5 parts of muramidase.

2. the cleaning and sterilizing piece of a kind of cleaning milk dirt according to claim 1, spot, which is characterized in that include following Proportion raw material by weight:

PH value adjustment agent: 35 parts of sodium carbonate, 20 parts of tartaric acid；

Filler: 10 parts of anhydrous sodium sulphate, 10 parts of zero water sodium metasilicate；

Chlorinating agent: 5 parts of sulfamic acid, 3 parts of sodium chloride；

Lubricant: 5 parts of polyethylene glycol powder, 0.5 part of magnesium stearate；

Emulsifier: 2.5 parts of anionic surfactant；

Disinfectant: 0.5 part of poly (hexamethylene), 2 parts of SODIUM PERCARBONATE；

Hard water resistance dose: 2 parts of disodium ethylene diamine tetraacetate；

Granulation binders: 1.5 parts of polyvinylpyrrolidone；

Enzyme preparation: 1.5 parts of protease, 1.5 parts of muramidase.

3. the cleaning and sterilizing piece of a kind of cleaning milk dirt according to claim 1, spot, which is characterized in that the disinfection tablet Preparation method, key step are as follows:

S1. it is sieved: 5-35 parts of sodium carbonate, 5-30 parts of tartaric acid, 5-30 parts of sulfamic acid, 5-40 parts of anhydrous sodium sulphate, sodium chloride 1-5 Part, 5-20 parts of polyethylene glycol powder, 0.5-15 parts of anionic surfactant, 0.1-5 parts of disodium ethylene diamine tetraacetate, SODIUM PERCARBONATE 0.5-5 parts, 0.5-25 parts of zero water sodium metasilicate, 0.1-3 parts of magnesium stearate, 0.5-5 parts of polyvinylpyrrolidone, proteinase-10 .1- 5 parts, 0.1-5 parts of muramidase, respectively cross 40-100 mesh, the material of excessively good sieve is respectively charged into stainless steel barrel cover it is close Envelope is weighed spare；

S2. binder and disinfection liquid mixture are prepared: purified water being placed in punching slurry pot, binder polyvinyl pyrrole is then added 0.5-5 parts of alkanone, it is formulated as the binder aqueous solution of 5-20% concentration, opens agitating paddle, it is sub- that poly- six are added under stirring 0.01-8 parts of methyl guanidine salt, it is heated to 70-80 DEG C, stops after continuing stirring 5-30 minutes, is cooled to room temperature, is weighed spare；

S3. it pelletizes: the sodium carbonate after sieving being put into wet granulator, then configured binder aqueous solution and thimerosal are added Enter to binder cast hopper, set Granulation time 30-600 seconds, opens cast hopper, opens stirring motor and chopping motor system , discharge piston is opened after Granulation time, opens agitating paddle, and sodium carbonate is made with 16-80 mesh net oscillating granulator in discharging Particle；

S4. it dries:

Sodium carbonate particle is put into baking oven dry；45-95 DEG C of drying temperature, drying time 4.5-5.5 hour；In drying process Per to carry out stirring every other hour, the dry particle finished is put into stainless steel barrel, weighs spare；

S5. it criticizes mixed: whole materials after sodium carbonate particle after drying and sieving is poured into mixing machine, batch doing time is 20-45 points Clock is weighed spare after mixing；

S6. tablet press machine hopper, tabletting tabletting: is added in mixed material.

4. the cleaning and sterilizing piece of a kind of cleaning milk dirt according to claim 1, spot, which is characterized in that application method is, Will clean milk dirt, milk stain cleaning and sterilizing piece dissolved in water with the ratio of 0.1-20%, then by needs clean feeding bottle, Breast pump, milk bottle brush, infant's muffler, baby toy, clothing, milk pot etc. are impregnated 5-30 minutes, then with clear water rinsed clean.

Technical field

The invention belongs to medicine and hygiene fields, and in particular to a kind of cleaning milk dirt, the cleaning and sterilizing piece of spot and its preparation Method.

Background technique

Milk dirt, milk stain, diatery supplement stain, protide, sweat stain, urine and stool stain are the common pollutants of infant article.Breast milk and match It is very nutritious in square milk.Containing a large amount of lipid, it is liable to stick to form milk dirt.Feeding bottle, milk pot are easy because of oil gas And it is smelly.It easily breeds bacterium and goes bad.Diatery supplement stain, protide, sweat stain, urine and stool stain are related to protide, inorganic salts, starch Class, carbohydrate, uric acid etc., the cleaning product that adult uses cannot be used for the washing of infant article, and traditional cleaning method is multi-purpose Scalding, steam disinfection, microwave sterilization, it is bothersome laborious.Infant article such as feeding bottle, breast pump, milk bottle brush, infant enclose If the cleaning of neck, baby toy, clothing, milk pot is not thorough, without disinfection, the newborn that stomach immunity is not perfected also It is very big threat.The present invention is directed to produce a kind of nontoxic, noresidue, nonirritant, the product of washing antibacterial.

Summary of the invention

It is an object of the invention to avoid the deficiencies in the prior art, a kind of cleaning milk dirt, milk stain, diatery supplement stain, urine and stool are provided Cleaning and sterilizing piece of stain and preparation method thereof and application method.It is materials safety of the present invention, nontoxic, green, environmentally friendly, it kills Bacterium range is wide, versatile, easy to use, easily stored, is not only applicable to family, is equally applicable to the public field such as kindergarten Institute, avoids cross-infection.There are other methods and the unrivaled advantage of product.

To achieve the above object, the technical scheme adopted by the invention is as follows: a kind of cleaning milk dirt, milk stain, diatery supplement stain, urine and stool stain Cleaning and sterilizing piece and preparation method thereof and application method, it is characterised in that include following proportion raw material by weight:

PH value adjustment agent: 5-35 parts of sodium carbonate, 5-30 parts of tartaric acid.

Filler: 5-40 parts of anhydrous sodium sulphate, 0.5-25 parts of zero water sodium metasilicate.

Chlorinating agent: 5-30 parts of sulfamic acid, 1-5 parts of sodium chloride.

Lubricant: 5-20 parts of polyethylene glycol powder, 0.1-3 parts of magnesium stearate.

Emulsifier: 0.5-15 parts of anionic surfactant.

Disinfectant: 0.01-8 parts of poly (hexamethylene), 0.5-5 parts of SODIUM PERCARBONATE.

Hard water resistance dose: 0.1-5 parts of disodium ethylene diamine tetraacetate.

Granulation binders: 0.5-5 parts of polyvinylpyrrolidone.

Enzyme preparation: .1-5 parts of proteinase-10,0.1-5 parts of muramidase

2. a kind of cleaning milk dirt, the cleaning and sterilizing piece and preparation method thereof of milk stain, diatery supplement stain, urine and stool stain and application method Preparation method, key step are as follows:

S1. it is sieved: 5-35 parts of sodium carbonate, 5-30 parts of tartaric acid, 5-30 parts of sulfamic acid, 5-40 parts of anhydrous sodium sulphate, sodium chloride 1-5 parts, 5-20 parts of polyethylene glycol powder, 0.5-15 parts of anionic surfactant, 0.1-5 parts of disodium ethylene diamine tetraacetate, excessively carbon Sour sodium 0.5-5 parts, 0.5-25 parts of zero water sodium metasilicate, 0.1-3 parts of magnesium stearate, 0.5-5 parts of polyvinylpyrrolidone, protease 0.1-5 parts, 0.1-5 parts of muramidase cross 40-100 mesh respectively, the material of excessively good sieve are respectively charged into stainless steel barrel and is covered Sealing is weighed spare.

S2. binder and disinfection liquid mixture are prepared: purified water being placed in punching slurry pot, binder polyethylene is then added 0.5-5 parts of pyrrolidones, it is formulated as the binder aqueous solution of 5-20% concentration, opens agitating paddle, is added under stirring poly- 0.01-8 parts of hexa-methylene guanidine salt, it is heated to 70-80 DEG C, stops after continuing stirring 5-30 minutes, is cooled to room temperature, is weighed standby With；

S3. it pelletizes: the sodium carbonate after sieving being put into wet granulator, then by configured binder aqueous solution and disinfection Liquid is added to binder cast hopper, sets Granulation time 30-600 second, open cast hopper, open stirring motor and shred motor into Row is pelletized, and discharge piston is opened after Granulation time, opens agitating paddle, and carbon is made with 16-80 mesh net oscillating granulator in discharging Sour sodium particle；

S4. it dries:

Sodium carbonate particle is put into baking oven dry；45-95 DEG C of drying temperature, drying time 4.5-5.5 hour.It is dried Per to carry out stirring every other hour in journey, the dry particle finished is put into stainless steel barrel, weighs spare；

S5. it criticizes mixed: whole materials after drying sodium carbonate particle and being sieved being poured into mixing machine, criticizes and does time as 20- It 45 minutes, weighs after mixing spare；

S6. tablet press machine hopper, tabletting tabletting: is added in mixed material.

3. a kind of cleaning milk dirt, the cleaning and sterilizing piece and preparation method thereof of milk stain, diatery supplement stain, urine and stool stain and application method Application method, it is characterised in that: carry out the cleaning and sterilizing piece for cleaning milk dirt, milk stain with the ratio of 0.5-20% in water molten Solution, then feeding bottle, breast pump, milk bottle brush, infant's muffler, baby toy, clothing, milk pot for needing to clean etc. are impregnated into 5-30 Minute (depending on pollution level), then with clear water rinsed clean.

The medicine have the advantages that

1. disinfectant uses poly (hexamethylene) and SODIUM PERCARBONATE, poly (hexamethylene) is a kind of cationic polymerization Object, antibacterial action mainly pass through solubilizing lipids, change the permeability of bacterial cell membrane, make endobacillary metabolism that obstacle occur And antibacterial.Has a broad antifungal spectrum, have the characteristics that it is colourless, odorless, to no skin irritation, nontoxicity, non-corrosive, especially to some The articles of high-temperature sterilization cannot be used.Only it need to be impregnated or be sprayed with the solution of 1 ‰ concentration, can reach satisfied kill in a short time Bacterium effect.Perfect children are not yet developed to immune system to be even more important.Poly (hexamethylene) is usually vitrifying bulk knot Structure cannot be used directly for tabletting, and the present invention is soluble in water by poly (hexamethylene) when binder is prepared in granulation, is heated to It 70-80 DEG C and stirs, sufficiently dissolves, solve the problems, such as that poly (hexamethylene) can not direct tablet compressing.SODIUM PERCARBONATE is in addition to energy Enough effective removal sebums, bloodstain, fruit stain and coffee stain, 1% solution can kill Escherichia coli, Portugal when being more than room temperature Grape bacterium, golden yellow streptococcus etc., can be effectively suppressed the breeding of liver viroid at high temperature.

2. enzyme preparation is compounded using muramidase and protease, it is a kind of native protein that muramidase, which is also referred to as lysozyme, Muramidase to gram positive bacteria, gram-negative bacteria, aerobic sporeformer, hay bacillus, bacillus licheniformis etc. all There is antibacterial action, and will not have an adverse effect to the human body cell of not cell wall.The enzyme can also kill enteron aisle corruption coccus, Increase enteron aisle resistance infection, it is worth mentioning at this point that, a small amount of muramidase is contained in fresh cow's milk and human milk, if in fresh milk or A certain amount of lysozyme is added in milk powder, not only there is antisepsis antistaling agent, and can reach the purpose for strengthening baby milk, Be conducive to the health of baby, the enzyme is very safe when being used for cleaning and sterilizing infant article.Muramidase has stronger heat resistanceheat resistant Property and cold resistance.100 DEG C at a temperature of still keep activity, muramidase will not because of solvent processing and inactivate, work as transfer When into aqueous solution, the vigor of muramidase can full recovery so that the present invention has preferable use environment, enzyme preparation activity It does not lose.Protease and muramidase cooperative system greatly increase enzymatic activity, and cleaning is more thorough, more rapidly, to bloodstain, mucus, rouge Class, albumen, urine and stool spot have good ability.

3. chlorinating agent uses sulfamic acid and sodium chloride.Sulfamic acid and sodium chloride can be slow, micro release chlorine, Our experiments show that chlorination muramidase and protease are in confrontation filterable virus, decomposition blood, mucus residue, excrement, vomitus There is better effect with other organic matters.The compounding of chlorinating agent and muramidase, so that the present invention is in antibacterial, antiviral, washing Effect become more preferable.Meanwhile sodium chloride have draw it is moist, can make moisture accelerate infiltration tablet, tablet dissolved speed accelerate.

4.PH value regulator uses sodium carbonate and tartaric acid.The pH value of piece agent solution is an important indicator in the present invention, If enzyme preparation is that 5.3-7.7 aqueous solution activity is most strong in pH value.The pH value that infant article also limits piece agent solution cannot mistake It is high and too low, in order to avoid stimulation skin or corrosion articles.

5. emulsifier uses anionic surfactant, anionic surfactant has mature production technology, raw material easy The features such as many advantages, such as obtaining, is applied widely, foam is high and fine and smooth, price is lower, especially with natural oil, starch, egg The raw materials such as white matter, sugar substitute petrochemical materials and produce novel surfactant, and performance is prominent, to protide, inorganic salts, shallow lake The washings such as powder class, carbohydrate, uric acid effect is good, harmless noresidue.The present invention can reduce production using anionic surfactant Cost increases product versatility, suitable for a great variety, the cleaning and disinfection of unlike material infant article.

6. hard water resistance dose uses disodium ethylene diamine tetraacetate, disodium ethylene diamine tetraacetate can be with the multivalence such as iron, copper, calcium, magnesium Ion chelating avoids calcium ions and magnesium ions in water to anionic surfactant precipitation at stable water soluble complex, It can prevent influence of the metal ion to enzymatic activity.Food-grade disodium ethylene diamine tetraacetate is widely used in food, drug etc. Field, it is very safe.

7. lubricant uses polyethylene glycol powder and magnesium stearate, polyethylene glycol powder and magnesium stearate have good lubrication Property, it can prevent occurring the problem of material adhesion formed punch in tableting processes.Keep tablet surface smooth, piece type is complete, can also subtract The excessive problem of few tablet weight variation.

8. filler uses anhydrous sodium sulphate and zero water sodium metasilicate, there is low in cost, the stable feature of slice weight.

9. granulation binders use polyvinylpyrrolidone, polyvinylpyrrolidone has excellent physiological inertia, is not involved in Human metabolism, and there is excellent biocompatibility, any stimulation is not formed to skin, mucous membrane, eye etc..It is advocated for the world One of three big medicinal new accessories.The stabilizer that enzyme preparation can be protected increases the hydrophily of tablet.In addition to this, polyethylene pyrrole Pyrrolidone has anti-dirt reprecipitation performance, can be enhanced washing ability, and when laundering of textile fabrics can prevent surfactant to skin Stimulation.

Specific embodiment

It is described below in conjunction with subordinate list a pair of principles and features of the present invention, the given examples are served only to explain the present invention, It is not intended to limit the scope of the present invention.