阅读说明：本技术 一种洗浴用含低分子透明质酸的浴盐 (Bath salt containing low-molecular hyaluronic acid for bath ) 是由 凌沛学 边玲 曾庆恺 邵华荣 亓金亮 于 2021-08-25 设计创作，主要内容包括：本发明公开了一种洗浴用含低分子透明质酸的浴盐,包含以下组分及其重量百分数：精制矿盐88.95％～97.895％,低分子透明质酸0.1％～1％,黄原胶0.005％～0.05％,木鱼石粉1％～5％,麦饭石粉1％～5％。制备的浴盐使用的低分子透明质酸具有良好的保湿保水作用；黄原胶易于涂布附着于皮肤,促进皮肤表面光滑；另添加纳米化的木鱼石粉和麦饭石粉,使水质矿物质化,能协助皮肤补充微量元素；适用于浴池、温泉水中,能更好地补充皮肤水分,延缓皮肤失水速率,起到充分保湿、细嫩美肤的效果。(The invention discloses bath salt containing low molecular hyaluronic acid for bathing, which comprises the following components in percentage by weight: 88.95-97.895% of refined mineral salt, 0.1-1% of low molecular hyaluronic acid, 0.005-0.05% of xanthan gum, 1-5% of Muyu stone powder and 1-5% of medical stone powder. The low molecular hyaluronic acid used in the prepared bath salt has good moisturizing effect; the xanthan gum is easy to coat and adhere to the skin, and promotes the skin surface to be smooth; nano Muyu stone powder and medical stone powder are added to mineralize the water quality and help the skin to supplement trace elements; is suitable for bathing pools and hot spring water, can better supplement skin moisture, delay the rate of skin dehydration, and has the effects of fully moisturizing, tendering and beautifying the skin.)

1. A bath salt containing low molecular hyaluronic acid for bathing is characterized by comprising the following components in percentage by weight: 88.95-97.895% of refined mineral salt, 0.1-1% of low molecular hyaluronic acid, 0.005-0.05% of xanthan gum, 1-5% of Muyu stone powder and 1-5% of medical stone powder.

2. The bath salt according to claim 1, comprising the following components in weight percent: 88.95 to 97.895 percent of refined mineral salt, 0.2 to 0.8 percent of low molecular hyaluronic acid, 0.005 to 0.05 percent of xanthan gum, 1 to 5 percent of Muyu stone powder and 1 to 5 percent of medical stone powder.

3. The bath salt according to claim 1, comprising the following components in weight percent: 88.95 to 97.895 percent of refined mineral salt, 0.3 to 0.6 percent of low molecular hyaluronic acid, 0.01 to 0.04 percent of xanthan gum, 1 to 5 percent of Muyu stone powder and 1 to 5 percent of medical stone powder.

4. The bath salt according to any one of claims 1 to 3, wherein the low molecular hyaluronic acid comprises low molecular hyaluronic acid or a salt thereof, and the low molecular hyaluronic acid salt is selected from one, two or more of sodium salt, potassium salt, calcium salt and zinc salt of low molecular hyaluronic acid.

5. The bath salt according to any one of claims 1 to 3, wherein the low-molecular weight hyaluronic acid or a salt thereof has a weight average molecular weight of 348 to 100000, further wherein the low-molecular weight hyaluronic acid or a salt thereof has a weight average molecular weight of 1000 to 50000, and further wherein the low-molecular weight hyaluronic acid or a salt thereof has a weight average molecular weight of 1000 to 2000.

6. The bath salt according to any one of claims 1 to 3, wherein the weight average molecular weight of the xanthan gum is 1 to 800 ten thousand, further selected from 1 to 500 ten thousand, and further selected from 1 to 100 ten thousand.

7. The bath salt according to any one of claims 1 to 3, wherein the particle size of the Muyu stone powder is 100 to 1000 nm; the particle size of the medical stone powder is 100-1000 nm.

8. The bath salt according to any one of claims 1 to 3, wherein the preparation method of the bath salt comprises the following steps: grinding the refined mineral salt, sieving with 100 mesh sieve, adding Muyu stone powder and Maifanitum powder, stirring, drying, adding low molecular hyaluronic acid and xanthan gum, stirring, drying, and packaging.

9. The bath salt according to any one of claims 1 to 3, wherein the bath salt is dissolved in water to a mass volume concentration of the low molecular weight hyaluronic acid in water of 0.01 to 0.1% at the time of use.

Technical Field

The invention belongs to bath preparations, and particularly relates to bath salt containing low-molecular hyaluronic acid for bathing.

Background

The existing bath products mainly comprise solid soaps, bath foam, bath salt, foaming bath agent and the like, and are suitable for various bath requirements. The solid soap, bath foam and bath salt can be used in shower for cleaning and caring skin, but have limited moisturizing and caring skin due to short time of skin. The bath salt and foaming bath agent can also be dissolved in water, such as domestic bathtub, bathing pool or hot spring, and are suitable for dipping bath. The existing common bath salt is added with more traditional Chinese medicine components, essential oil, spice and the like, after the bath salt is dissolved in warm water, the effective components are fully penetrated into the skin by utilizing the osmotic pressure balance effect of the salt through the long-time contact of the skin and the effective components dissolved in the water, and in addition, the warm water can promote the blood circulation and the pore opening, so that the absorption of the effective components of the traditional Chinese medicine, the mineral substances, the essential oil and the like is more facilitated, and a certain curative effect is achieved. However, sodium chloride, which is a main component of bath salt, is not friendly to dry or sensitive skin, and excessive cleaning or mechanical stimulation may be caused by using the bath salt, so that skin prickling and dry feeling are easily caused. If the health state of the skin is not ideal, especially for middle-aged and elderly people, or people in a drier environment, the water retention capacity of the skin is insufficient, and if the skin is immersed in hot spring or a bath pool, due to the great difference between the external environment and the water environment, once the immersion bath is finished, the skin loses water quickly, and the skin is not beneficial to the health.

Disclosure of Invention

In order to solve the above problems, the present invention provides a bath salt containing low molecular hyaluronic acid for bathing.

In order to achieve the above object, the present invention adopts the following technical solutions.

A bath salt containing low molecular hyaluronic acid for bathing comprises the following components in percentage by weight: 88.95-97.895% of refined mineral salt, 0.1-1% of low molecular hyaluronic acid, 0.005-0.05% of xanthan gum, 1-5% of Muyu stone powder and 1-5% of medical stone powder.

Further, the bath salt containing the low molecular hyaluronic acid for bathing comprises the following components in percentage by weight: 88.95 to 97.895 percent of refined mineral salt, 0.2 to 0.8 percent of low molecular hyaluronic acid, 0.005 to 0.05 percent of xanthan gum, 1 to 5 percent of Muyu stone powder and 1 to 5 percent of medical stone powder.

Further, the bath salt containing the low molecular hyaluronic acid for bathing comprises the following components in percentage by weight: 88.95 to 97.895 percent of refined mineral salt, 0.3 to 0.6 percent of low molecular hyaluronic acid, 0.01 to 0.04 percent of xanthan gum, 1 to 5 percent of Muyu stone powder and 1 to 5 percent of medical stone powder.

The low molecular hyaluronic acid comprises low molecular hyaluronic acid or salt thereof, and the low molecular hyaluronic acid salt is selected from one, two or more of sodium salt, potassium salt, calcium salt and zinc salt of the low molecular hyaluronic acid.

The weight average molecular weight of the low molecular weight hyaluronic acid and the salt thereof is 348-100000, the weight average molecular weight of the low molecular weight hyaluronic acid or the salt thereof is further selected to be 1000-50000, and the weight average molecular weight of the low molecular weight hyaluronic acid and the salt thereof is further selected to be 1000-2000.

The weight average molecular weight of the xanthan gum is 1-800 ten thousand, the weight average molecular weight of the xanthan gum is further selected to be 1-500 ten thousand, and the weight average molecular weight of the xanthan gum is further selected to be 1-100 ten thousand.

The particle size of the Muyu stone powder is 100-1000 nm.

The particle size of the medical stone powder is 100-1000 nm.

The preparation method of the bath salt comprises the following steps: grinding mineral salt, sieving with 100 mesh sieve, adding Muyu stone powder and Maifanitum powder, stirring, drying, adding low molecular hyaluronic acid and xanthan gum, stirring, drying, and packaging.

When the bath salt is used, the prepared bath salt is dissolved in water, so that the mass volume concentration of the low molecular weight hyaluronic acid in the water is 0.01-0.1%.

The invention has the beneficial effects that: the low molecular weight hyaluronic acid used by the bath salt prepared by the invention has good moisturizing effect, has better curative effect in dermatology applications such as promotion of skin healing, eczema, filling and the like, is more beneficial to skin absorption, and can directly reach the dermis layer to fill the skin. The xanthan gum is easy to coat and adhere to the skin due to good viscosity, and can effectively inhibit pruritus, promote healing, resist inflammation and promote skin surface smoothness. And nano Muyu stone powder and medical stone powder are added to mineralize water quality and help skin to supplement trace elements. The bath salt prepared by the invention has no irritant component, is suitable for bathing pools and hot spring water, can better supplement skin moisture, delay the water loss rate of the skin, and has the effects of fully moisturizing, tendering and beautifying the skin.

Detailed Description

The present invention is further illustrated in detail by referring to the following specific examples, but the scope of the present invention is by no means limited to the following examples.

Example 1

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight average molecular weight of 10 ten thousand and 0.05% of xanthan gum with the weight average molecular weight of 800 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 2

Taking 96.995% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 1% of Muyu stone powder and 1% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight average molecular weight of 10 ten thousand and 0.005% of xanthan gum with the weight average molecular weight of 800 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 3

Taking 97.895% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 1% of Muyu stone powder and 1% of medical stone powder, uniformly stirring and drying, adding 0.1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 5 ten thousand, 0.005% of xanthan gum with the weight-average molecular weight of 500 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.01 percent.

Example 4

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight average molecular weight of 1 ten thousand and 0.05% of xanthan gum with the weight average molecular weight of 200 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 5

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 5000 and 0.05% of xanthan gum with the weight-average molecular weight of 100 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 6

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 2000 and 0.05% of xanthan gum with the weight-average molecular weight of 100 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 7

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 2000 and 0.05% of xanthan gum with the weight-average molecular weight of 50 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 8

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 1000, 0.05% of xanthan gum with the weight-average molecular weight of 100, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 9

Taking 88.95% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 1000 and 0.05% of xanthan gum with the weight-average molecular weight of 1 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.1 percent.

Example 10

Taking 89.15% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.8% of low-molecular sodium hyaluronate with the weight-average molecular weight of 1000, 0.05% of xanthan gum with the weight-average molecular weight of 20 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.08 percent.

Example 11

Taking 89.36% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.6% of low-molecular sodium hyaluronate with the weight-average molecular weight of 500 and 0.04% of xanthan gum with the weight-average molecular weight of 20 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.06%.

Example 12

Taking 89.67% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.3% of low-molecular sodium hyaluronate with the weight-average molecular weight of 500 and 0.03% of xanthan gum with the weight-average molecular weight of 20 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.03 percent.

Example 13

Taking 89.68% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.3% of low-molecular sodium hyaluronate with the weight-average molecular weight of 500, 0.02% of xanthan gum with the weight-average molecular weight of 20 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.03 percent.

Example 14

Taking 89.68% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.3% of low-molecular sodium hyaluronate with the weight-average molecular weight of 500, 0.02% of xanthan gum with the weight-average molecular weight of 20 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.03 percent.

Example 15

Taking 89.79% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.2% of low-molecular sodium hyaluronate with the weight-average molecular weight of 500 and 0.01% of xanthan gum with the weight-average molecular weight of 40 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.05 percent.

Example 16

Taking 89.89% of refined mineral salt according to the following weight percentage, grinding, sieving by a 100-mesh sieve, adding 5% of Muyu stone powder and 5% of medical stone powder, uniformly stirring and drying, adding 0.1% of low-molecular sodium hyaluronate with the weight-average molecular weight of 500 and 0.01% of xanthan gum with the weight-average molecular weight of 40 ten thousand, uniformly stirring, drying and packaging to obtain the product. The prepared bath salt is dissolved in water at 40 ℃ to ensure that the mass volume concentration of the low molecular sodium hyaluronate in the water is 0.01 percent.

Comparative example 1

A bath salt containing no hyaluronic acid was prepared in the same procedure as in example 6, except that hyaluronic acid was not added.

Comparative example 2

A bath salt containing no hyaluronic acid was prepared in the same procedure as in example 8, except that hyaluronic acid was not added.

Comparative example 3

A bath salt containing no hyaluronic acid was prepared in the same procedure as in example 10, except that hyaluronic acid was not added.

Comparative example 4

A bath salt containing no hyaluronic acid was prepared in the same procedure as in example 15, except that hyaluronic acid was not added.

Comparative example 5

A bath salt containing no xanthan gum was prepared in the same procedure as in example 6, except that no xanthan gum was added.

Comparative example 6

A bath salt containing no xanthan gum was prepared in the same procedure as in example 9, except that xanthan gum was not added.

Comparative example 7

A bath salt containing no xanthan gum was prepared in the same procedure as in example 10, except that no xanthan gum was added.

Comparative example 8

The same procedure as in example 6 was carried out except that neither hyaluronic acid nor xanthan gum was added, to prepare a common bath salt containing no hyaluronic acid and xanthan gum.

Test example: determination of skin moisture content and Perkin Water loss

A certain number of healthy adult females are selected to participate in the test, the age is 31-40 years, and all subjects have no skin diseases or systemic diseases on the skin. The subjects belong to dry skin types, and the data are all less than 30 through skin moisture content tests, and the subjects are considered to belong to dry skin types. The skin of the hand and the upper arm of the testee is cleaned by the perfumed soap of the same brand 12 hours before the test, and no moisturizing treatment is carried out, such as smearing skin lotion and the like. The environmental temperature of the test room is kept at about 22-25 ℃, and the relative humidity is 45-55%. The moisture content of the skin is measured by adopting a CM825 moisture test probe, and the moisture loss rate of the epidermis is measured by adopting a TM300 moisture loss rate test probe.

(1) On the day of the test, the subject was immersed in water containing the bath salt of the present invention for 20min at 40 ℃ after exposing his arms in the test room for 30 min. The water content of the skin and the transepidermal water loss rate are monitored before immersion and after removal for 0.5, 2, 4 and 6 hours respectively. The measuring area is a fixed area of 5cm multiplied by 5cm on the inner side of the arm, each area is fixedly measured according to a certain sequence, each person detects for 3 times, the average value is calculated, and a self-use front-back comparison mode is adopted. In addition, warm water of 40 ℃ was used as a blank group, and 10% glycerin was applied as a control.

(2) Separately, bath salts containing no hyaluronic acid or xanthan gum were prepared as blanks according to comparative examples 1, 2, 3 and 4, and the skin moisture content and the transepidermal water loss rate were measured according to the same method as in item (1).

(3) Further, bath salts containing no xanthan gum were prepared as blanks according to comparative examples 5, 6 and 7, and the skin moisture content and the transepidermal water loss rate were measured according to the same method as in item (1).

(4) In addition, according to comparative example 8, bath salts containing no hyaluronic acid and xanthan gum were prepared as blanks, and the skin moisture content and the transepidermal water loss rate were measured in the same manner as in item (1).

As a result: after all subjects use the bath salt, no adverse reactions such as allergy and the like are seen, and the results of the test on the water content of the skin and the epidermal water loss rate are analyzed through statistical tests (the test results are shown in tables 1-2), so that the results show that in the bath salt containing the low-molecular hyaluronic acid, the weight-average molecular weight of the low-molecular hyaluronic acid and the salt thereof is 348-100000, the weight-average molecular weight of the xanthan gum is 1-800 ten thousand, and the content of the xanthan gum is 0.005-0.05%, when the bath salt is added into water at 40 ℃, the water content of the skin is obviously increased after the skin is bathed, and the epidermal water loss rate is obviously reduced even if the skin is not subjected to moisture retention treatment, and particularly the bath salt has an obvious effect after the skin is taken out for 6 hours, so that the bath salt can deeply improve the dry and tight state of the skin and repair the skin barrier, and the effect of simultaneously adding the hyaluronic acid group and the xanthan gum is more obvious.

TABLE 1 skin moisture content

TABLE 2 Perdermic Water loss Rate