Chinese herbal medicine prescription for treating uterine cancer

文档序号:1837822 发布日期:2021-11-16 浏览:20次 中文

阅读说明:本技术 一种用于治疗子宫癌的中草药方 (Chinese herbal medicine prescription for treating uterine cancer ) 是由 谭明友 于 2021-08-25 设计创作,主要内容包括:本发明公开一种用于治疗子宫癌的中草药方,其由苏铁、火炭母、茅莓、蛇床子、白花蛇舌草、红枣、甘草组成,本发明根据子宫癌的病机,诸药合理配伍,协同作用,具有清热解毒、消肿散结、活血止痛等功效,可阻断癌细胞、提高机体免疫力,对子宫癌进行有效的治疗,特别是Ⅰ、Ⅱ、Ⅲ期的子宫癌,并且还可用于治疗白带过多、子宫炎症等症。(The invention discloses a traditional Chinese herbal medicine prescription for treating uterine cancer, which consists of cycas revoluta, Chinese knotweed herb, Japanese raspberry, common cnidium fruit, spreading hedyotis herb, red date and liquorice.)

1. A traditional Chinese herbal medicine prescription for treating uterine cancer is characterized by comprising the following raw material medicines:

cycas revoluta, Chinese knotweed, rubus parvifolius, fructus cnidii, oldenlandia diffusa, red dates and liquorice.

2. The Chinese herbal medicine prescription for treating uterine cancer according to claim 1 is characterized by comprising the following raw material medicines in parts by weight:

80-120 parts of cycas revoluta, 80-120 parts of Chinese knotweed herb, 20-80 parts of rubus parvifolius, 10-30 parts of fructus cnidii, 80-120 parts of oldenlandia diffusa, 10-50 parts of red dates and 5-30 parts of liquorice.

3. The Chinese herbal medicine prescription for treating uterine cancer according to claim 1 is characterized by comprising the following raw material medicines in parts by weight:

100 parts of cycas, 100 parts of Chinese knotweed, 50 parts of rubus parvifolius, 15 parts of fructus cnidii, 100 parts of oldenlandia diffusa, 30 parts of red dates and 10 parts of liquorice.

Technical Field

The invention relates to the technical field of medicines, and in particular relates to a traditional Chinese medicine formula for treating uterine cancer.

Background

Uterine cancer, actually endometrial cancer, occurs in the lining of the uterus. It is a common cancer in the female reproductive system, with the fourth most common cancer in women. It is common in women 50-60 years old, and occurs after menopause. The incidence of recent years is on the rise worldwide. Can be transferred to many parts of the body: from the uterus down to the cervical canal and from the fallopian tubes up to the ovaries; can also infiltrate into the tissues around the uterus; or to sites distant from the uterus by the lymphatic system and blood circulation.

The causes of uterine cancer are many, and according to epidemiological investigation and clinical case study, the following causes are common: women who are never pregnant, are over obese, or have diabetes. ② women which have been in climacteric (menopause) and receive hormone therapy for a long time. ③ if tamoxifen, a drug used to treat breast cancer, is taken for a long period of time, it also increases the risk of uterine cancer (this risk is very slight and administration of tamoxifen far outweighs the risk). The uterus has long-term chronic inflammation, poor sexual hygiene, premature birth and 0 prolific birth, the treatment of the uterus still mainly adopts operation, and in addition, the uterus is given radiotherapy, chemotherapy, endocrine therapy, molecular targeted therapy and the like, although the uterus has certain curative effect, the chemotherapy has large side effect, the body of a patient is weak, and the tolerance is poor. And for patients with weak constitution, the patients may not bear the side effects of surgery or chemotherapy treatment, but the survival time of the patients is affected.

Disclosure of Invention

Therefore, based on the above background, the present invention aims to provide a Chinese herbal medicine for treating uterine cancer with less side effects and remarkable therapeutic effect.

The technical scheme provided by the invention is as follows:

a traditional Chinese herbal medicine prescription for treating uterine cancer comprises the following raw material medicines:

cycas revoluta, Chinese knotweed, rubus parvifolius, fructus cnidii, oldenlandia diffusa, red dates and liquorice.

Further, the cycas revoluta is cycas revoluta leaves.

Further, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight:

80-120 parts of cycas revoluta, 80-120 parts of Chinese knotweed herb, 20-80 parts of rubus parvifolius, 10-30 parts of fructus cnidii, 80-120 parts of oldenlandia diffusa, 10-50 parts of red dates and 5-30 parts of liquorice.

Further, the traditional Chinese medicine composition comprises the following raw material medicines in parts by weight:

100 parts of cycas, 100 parts of Chinese knotweed, 50 parts of rubus parvifolius, 15 parts of fructus cnidii, 100 parts of oldenlandia diffusa, 30 parts of red dates and 10 parts of liquorice.

Furthermore, the invention can be added with various conventional auxiliary materials required by preparing different dosage forms to prepare any common oral dosage form, such as: pill, powder, tablet, capsule, oral preparation, etc.

The raw materials used in the formula of the invention are as follows: folium Perillae has effects of astringing, stopping bleeding, removing toxic substance, and relieving pain, and can be used for treating hemorrhage, gastritis, gastric ulcer, hypertension, neuralgia, amenorrhea, cancer, etc.; the herb of Chinese knotweed is cool in property, has the effects of clearing away heat and toxic materials, promoting diuresis, eliminating stagnation, cooling blood and relieving itching, and is used for treating dyspepsia, hepatitis, mastitis, mycotic vaginitis, leucorrhea and the like; the rubus parvifolius is cool in nature, has the effects of clearing heat and cooling blood, eliminating stagnation and relieving pain, and is used for treating nephritis edema, urinary system infection, irregular menstruation, leucorrhea and the like; fructus Cnidii has warm nature, and has effects of warming kidney, tonifying yang, eliminating dampness, dispelling pathogenic wind, and can be used for treating sexual impotence, cold womb, leukorrhagia due to cold-dampness, damp arthralgia, lumbago, etc.; the oldenlandia diffusa is cool in nature, has the effects of clearing heat and removing toxicity, inducing diuresis to reduce edema, and activating blood circulation to stop pain, and is used for treating sore furuncle pyogenic infections, damp-heat jaundice, dysuria and the like; the red dates have warm property, tonify middle-jiao and qi, nourish blood and tranquilize mind, strengthen spleen and stomach and moderate drug property; the liquorice has mild nature, tonifies spleen and qi, clears heat and toxic materials, eliminates phlegm and stops cough, relieves spasm and pain, and harmonizes the drugs, and is used for treating weakness of spleen and stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough and profuse sputum, and spasm and pain of epigastrium and four limbs, and relieving drug toxicity, fulness and the like.

Modern traditional Chinese medicine considers that the disease is spleen and kidney deficiency, water cannot be transported and dissolved, water dampness is accumulated for a long time, sound and heat toxicity is accumulated between belt vessels, and finally, the toxicity of damp and heat and blood are all under the condition; the traditional Chinese medicine composition is used for treating diseases caused by liver qi stagnation due to kidney yin deficiency and liver stagnation and blood heat, and can be used for treating diseases caused by heat-induced injury of thoroughfare and conception vessels for a long time, clearing heat, detoxifying, strengthening body resistance and strengthening vitality, so that the effects of clearing heat, detoxifying, dissipating stagnation and relieving pain are realized by adopting the compatibility of cycas revolute, herb of Chinese knotweed, rubus parvifolius, oldenlandia diffusa and liquorice, and the effects of tonifying qi, strengthening body resistance and strengthening vitality are realized by matching the fructus cnidii and the red dates.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1: a traditional Chinese herbal medicine formula for treating uterine cancer comprises the following raw material medicines in parts by weight:

100 parts of cycas, 100 parts of Chinese knotweed, 50 parts of rubus parvifolius, 15 parts of fructus cnidii, 100 parts of oldenlandia diffusa, 30 parts of red dates and 10 parts of liquorice.

When in use, the traditional Chinese medicine composition is prepared into an oral dosage form, and one dosage is prepared into 50ml of oral liquid.

The use method comprises the following steps: one dose is taken in the morning and at night each day.

Example 2: acute toxicity test

After 20 Kunming mice are fed normally, the oral liquid in the embodiment 1 is fed through the mouth of the mice, the mice are fed according to the amount of 0.5g/10, and the continuous observation is carried out for 7 days, so that the results show that after the administration of the oral liquid, all indexes of diet, drinking water, vitality, defecation and the like of the mice are normal as those of a control group, all the mice do not die in the test, the mice grow well, the respiration and the activity are normal, the drinking water, the diet and the defecation are normal, and no abnormal secretion exists in the mouth, the nose and the eyes. The random selection 4 was performed only for dissection, and no pathological changes were observed in each organ.

Example 3: subacute toxicity test

After 10 Kunming mice were fed normally, the oral preparation of example 1 was orally administered, and the mice were fed with the oral preparation in an amount of 0.5g/10g, and after 40 days, clinical symptoms and changes in body weight of the rats in each group were observed and measured, and 4 mice were randomly selected and subjected to a dissection to observe changes in the tissues of organs such as heart, liver, spleen, lung, and kidney. The experimental rats grow well, breathe and move normally, drinking water, diet and defecation are normal, and no abnormal secretion exists in the mouth, nose and eyes; the rat has no morbidity and mortality; and (3) splitting results: the weight of heart, liver, spleen, lung and kidney were not different significantly. The visceral organs of the eye have no blood-filling or bleeding spots; the color and the form are normal, and no pathological changes of organs are seen.

The experimental results of the embodiment 2 and the embodiment 3 show that the traditional Chinese medicine formula of the invention is non-toxic and has no side effect.

Example 4: typical case

Case 1: since irregular bleeding of the vagina is frequent, the vagina often feels drop and the lower abdomen often feels weak, the uterus cancer stage II is confirmed by the combination of CT examination results and pathological analysis after going to a hospital for examination in 2014, and the uterus cancer stage II is diagnosed by the combination of CT examination results and the fear of damage caused by chemotherapy, so that the traditional Chinese medicine is selected for conservative treatment, and after the oral liquid prepared by the herbal medicine formula is taken for 2 weeks, the symptoms are obviously relieved, and after the oral liquid is taken for 2 months, the symptoms basically disappear.

Case 2: in the 31 year old woman, the result of B-ultrasonography shows that the endometrium thickness of the woman is abnormal in 2016 gynecological examination, so that the uterus cancer stage I is confirmed by performing vaginal ultrasonography and combining pathological analysis, and the result of recheck is normal after the woman takes the oral liquid prepared from the Chinese herbal medicine formula for 4 weeks continuously.

Case 3: luoqi, female, 51 years old and 2019 years old, irregular bleeding often occurs in vagina and is checked, the examination finds that fornix disappears behind the vagina, cervix uteri has 1 vegetable-shaped swelling matter of about 2cm multiplied by 2cm in size, the quality is crisp, bleeding easily occurs when touching, the left side accessory touches 1 sac solid packing block of about 5cm in size, the uterus cancer stage III is confirmed by combining pathological analysis, because the physique of a patient can not be operated and chemo-treated, the oral liquid prepared by the Chinese herbal medicine formula is started to be taken, after 2 months of continuous taking, vaginal bleeding is obviously reduced, cysts are obviously reduced, and after 8 months of continuous taking, the cysts basically disappear.

The present invention and the embodiments thereof have been described above, but the description is not limited thereto, and the embodiment shown is only one of the embodiments of the present invention, and the actual structure is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

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