阅读说明：本技术 膜 (Film ) 是由 丹尼尔·布兰奎特 艾米莉·勒鲁 维罗尼克·米高尼 于 2020-02-18 设计创作，主要内容包括：一种特别用于再生牙周韧带、防止粘连形成或组织再生和重建的膜,包括至少一个由纤维(F)制成的织物层(N1),所述纤维(F)由至少一种聚合物制备,其特征在于：-纤维(F)不含施胶剂,-所述织物层(N1)具有以无规或对齐方式设置的纤维的非织造布置,和-所述纤维(F)涂覆有PolyNaSS(聚苯乙烯磺酸钠)。(A membrane, particularly for regenerating periodontal ligaments, preventing adhesion formation or tissue regeneration and reconstruction, comprising at least one fabric layer (N1) made of fibers (F) made of at least one polymer, characterized in that: -the fibers (F) are free of sizing agent, -the fabric layer (N1) has a non-woven arrangement of fibers arranged in a random or aligned manner, and-the fibers (F) are coated with polynauss (sodium polystyrene sulfonate).)

1. Membrane, in particular for regenerating periodontal ligaments, preventing adhesion formation or tissue regeneration and reconstruction, comprising at least one fabric layer (N1, N1', N2, N3; N4; N61, N62, N63, N64, N65) made of fibers (F) made of at least one polymer, characterized in that:

-the fibres (F) are free of sizing agent,

-the fabric layer (N1, N1', N2, N3; N4; N61, N62, N63, N64, N65) has a non-woven arrangement of fibres arranged in a random or aligned manner, and

-the fibers (F) are coated with PolyNaSS (sodium polystyrene sulfonate).

2. The film of claim 1, wherein the polymer is selected from the group consisting of poly (epsilon-caprolactone) (PCL), poly (dioxanone) (PDO), a copolymer of poly (epsilon-caprolactone) (PCL) and poly (dioxanone) (PDO), polyethylene terephthalate (PET), and polypropylene (PP).

3. The membrane according to any one of the preceding claims, wherein the fabric layer (N4) comprises pores (H).

4. The membrane according to any one of the preceding claims, wherein the fabric layer (N3) has a thickness and a fiber density, the fiber density varying in a gradual gradient over the thickness.

5. The membrane according to any of the preceding claims, wherein the fabric layer (N1, N1', N2, N3; N61, N62, N63, N64, N65) is provided on a substrate (S1, S2, S3).

6. The membrane according to any one of the preceding claims, comprising two fabric layers (N1, N1', N2, N3) disposed on either side of a substrate (S1, S2, S3).

7. The membrane according to claim 4 or 5, wherein the porosity of the substrate (S1, S2, S3) is smaller than the porosity of the fabric layer (N1, N1', N2, N3).

8. The film of claim 4, 5 or 6, wherein the substrate (S1, S2, S3) is selected from:

-a film of poly (epsilon-caprolactone) (PCL),

-a poly (dioxanone) (PDO) film,

-a polyethylene terephthalate (PET) film,

-a film of polypropylene (PP),

-a non-woven fabric web, advantageously made of poly (epsilon-caprolactone) (PCL) and/or poly (dioxanone) (PDO), having a fiber density greater than that of the fabric layer (N1, N1', N2, N3).

9. Multilayer structure (M1; M2) comprising:

-a ceramic substrate (S5), advantageously tricalcium phosphate, and preferably beta-tricalcium phosphate (beta TCP),

-the film of any one of the preceding claims, advantageously made of poly (epsilon-caprolactone) (PCL), and

-optionally, a cohesive interface (Ic) disposed between the ceramic substrate (S5) and the film.

10. A dressing for application to a skin wound, the dressing comprising a substrate (S6) and at least one film according to any one of claims 1 to 7.

11. Method for manufacturing a membrane, in particular for regenerating periodontal ligaments, comprising at least one layer of fabric (N1, N1', N2, N3; N4; N61, N62, N63, N64, N65) made of fibers (F) made of at least one polymer, said method comprising the steps of:

a) obtaining a polymer fiber (F) free of sizing agent,

b) depositing the polymer fibers (F) in a random or aligned manner to form a nonwoven fabric layer (N1, N1', N2, N3; n4; n61, N62, N63, N64, N65),

c) in the nonwoven fabric layer (N1, N1', N2, N3; n4; n61, N62, N63, N64, N65) onto the fibers.

12. The method of claim 11, wherein the polymer is selected from the group consisting of poly (epsilon-caprolactone) (PCL), poly (dioxanone) (PDO), a copolymer of poly (epsilon-caprolactone) (PCL) and poly (dioxanone) (PDO), polyethylene terephthalate (PET), and polypropylene (PP).

13. Method according to claim 11 or 12, wherein a layer of non-woven fabric (N1, N1', N2, N3) is deposited on one or both sides of a substrate (S1, S2, S3), said substrate (S1, S2, S3) being selected from:

-a film of poly (epsilon-caprolactone) (PCL),

-a poly (dioxanone) (PDO) film,

-a polyethylene terephthalate (PET) film,

-a film of polypropylene (PP),

-a non-woven fabric web, advantageously made of poly (epsilon-caprolactone) (PCL) and/or poly (dioxanone) (PDO), having a fiber density greater than that of the fabric layer (N1, N1', N2, N3).