阅读说明：本技术 杀螨组合物及其应用 (Acaricidal composition and application thereof ) 是由 吴泽伟 于 2021-08-27 设计创作，主要内容包括：本发明属于杀螨组合物技术领域,公开了一种杀螨组合物及其应用。其中,本发明提供的杀螨组合物,包括活性主剂及助剂,所述活性主剂包括乙螨唑及烷基乙基磺酸盐,其中,所述乙螨唑及所述烷基乙基磺酸盐的质量比为1：0.1～10。采用乙螨唑及烷基乙基磺酸盐作为活性主剂,通过乙螨唑及烷基乙基磺酸盐的复配,且乙螨唑及烷基乙基磺酸盐的质量比为1：0.1～10时,制备得到的杀螨组合物可以对螨虫的螨卵、幼虫及成虫进行全面有效防治,具有明显的增效作用,防治效果好,且降低了杀螨组合物的使用剂量,减少了用药次数,不仅大大降低了用药成本,而且大大减少了对环境的影响,绿色环保。(The invention belongs to the technical field of acaricidal compositions, and discloses an acaricidal composition and application thereof. The acaricidal composition provided by the invention comprises an active main agent and an auxiliary agent, wherein the active main agent comprises etoxazole and alkyl ethyl sulfonate, and the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.1 to 10. The etoxazole and the alkyl ethyl sulfonate are adopted as active main agents, and are compounded through the combination of the etoxazole and the alkyl ethyl sulfonate, and the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.1-10 hours, the prepared acaricidal composition can be used for comprehensively and effectively controlling acarid eggs, larvae and adults of acarids, has obvious synergistic effect and good control effect, reduces the dosage of the acarid killing composition, reduces the drug use frequency, greatly reduces the drug use cost, greatly reduces the influence on the environment, and is green and environment-friendly.)

1. The acaricidal composition is characterized by comprising an active main agent and an auxiliary agent, wherein the active main agent comprises etoxazole and alkyl ethyl sulfonate, and the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.1 to 10.

2. An acaricidal composition according to claim 1, characterized in that: the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.5 to 5.

3. An acaricidal composition according to claim 1, characterized in that: the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.3 to 3.

4. An acaricidal composition according to claim 1, characterized in that: the auxiliary agent comprises at least one of a solvent, an emulsifier, a wetting agent, a stabilizer, a dispersant, a thickener, a pH regulator, a defoaming agent and an antifreezing agent.

5. An acaricidal composition according to any one of claims 1 to 4, characterized in that: also included are modified supports.

6. An acaricidal composition according to claim 5, characterized in that: the processing method of the modified carrier comprises the following steps: providing a carrier, calcining the carrier to obtain a first-stage carrier, providing the blades of paris polyphylla, the blades of iris tectorum and the blades of oleander, drying to make the blades of paris polyphylla, the blades of iris tectorum and the blades of oleander crisp, crushing to obtain plant powder, stirring and mixing the first-stage carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier.

7. An acaricidal composition according to claim 6, characterized in that: the carrier comprises at least one of kaolin, diatomite and attapulgite.

8. An acaricidal composition according to claim 6, characterized in that: in the operation of calcining the carrier to obtain the primary carrier, the calcining temperature is controlled to be 180-230 ℃, and the calcining time is 1-2 h.

9. An acaricidal composition according to claim 6, characterized in that: and in the operation of providing the paris polyphylla leaves, the iris tectorum leaves and the oleander leaves and drying, controlling the drying temperature to be 38-48 ℃.

10. Use of an acaricidal composition according to any one of claims 1 to 9 for controlling panonychus citri.

Technical Field

The invention relates to the technical field of pesticide acaricide, in particular to an acaricidal composition and application thereof.

Background

The citrus contains rich health-care substances for human bodies, is a fruit with rich nutrition, is one of important origin places of citrus in China, has rich citrus resources and various excellent varieties, has more than 4000 years of cultivation history, becomes a precious fruit for human beings after long-term cultivation and selection, and is a fruit which is frequently eaten by people in daily life.

However, in the citrus planting process, the problem of plant diseases and insect pests exists, wherein panonychus ulmi is a main insect pest which harms the normal growth of citrus, and the panonychus ulmi punctures the epidermis of citrus leaves through mouthparts of the panonychus ulmi and sucks juice, so that the citrus leaves show countless grey speckles, the leaves are turned grey to grey and fallen leaves are caused, the normal growth and yield of citrus fruits are influenced, and the existing acaricide has the problem of poor control effect and cannot achieve the ideal mite control effect.

Disclosure of Invention

Based on the above, the acaricidal composition and the application thereof are needed.

In order to achieve the purpose, the invention adopts the following technical scheme:

the acaricidal composition comprises an active main agent and an auxiliary agent, wherein the active main agent comprises etoxazole and alkyl ethyl sulfonate, and the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.1 to 10.

In one embodiment, the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: 0.5 to 5.

In one embodiment, the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: 0.3 to 3.

In one embodiment, the adjuvant includes at least one of a solvent, an emulsifier, a wetting agent, a stabilizer, a dispersant, a thickener, a pH adjuster, a defoamer, and an antifreeze.

In one embodiment, a modified support is also included.

In one embodiment, the modified support is treated by: providing a carrier, calcining the carrier to obtain a first-stage carrier, providing the blades of paris polyphylla, the blades of iris tectorum and the blades of oleander, drying to make the blades of paris polyphylla, the blades of iris tectorum and the blades of oleander crisp, crushing to obtain plant powder, stirring and mixing the first-stage carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier.

In one embodiment, the carrier comprises at least one of kaolin, diatomaceous earth, and attapulgite.

In one embodiment, in the operation of calcining the carrier to obtain the primary carrier, the calcining temperature is controlled to be 180 ℃ to 230 ℃ and the calcining time is controlled to be 1h to 2 h.

In one embodiment, in the providing and drying operation of the paris polyphylla leaves, the iris tectorum leaves and the oleander leaves, the drying temperature is controlled to be 38-48 ℃.

The invention also provides application of the acaricidal composition in controlling panonychus citri.

Compared with the prior art, the invention has the following advantages and technical effects:

(1) the acaricidal composition provided by the invention adopts etoxazole and alkyl ethyl sulfonate as active main agents, wherein etoxazole has a contact killing effect, can effectively inhibit the embryo formation of mite eggs when contacting with mite eggs, and can also effectively inhibit the process from the molting of young mites to adult mites, etoxazole has a good control effect on eggs and young mites of panonychus citri, etoxazole can also influence the reproductive function of female adult mites and has a good sterile effect on female adult mites, however, the control effect of etoxazole on adult mites is general, alkyl ethyl sulfonate can cause the paralysis of adult mite pests and cause the dehydration death of the adult mite pests, the thermal stability of alkyl ethyl sulfonate is good, the pesticide effect is not influenced by temperature, the drug stability of the prepared acaricidal composition can be ensured, and the alkyl ethyl sulfonate has strong contact killing activity on adult mites and the adult mites of pests such as panonychus citri, tetranychus cinnabarinus, two-spotted spider mites of strawberries and the like, therefore, the etoxazole and the alkyl ethyl sulfonate are compounded, and the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.1-10 hours, the prepared acaricidal composition can be used for comprehensively and effectively controlling acarid eggs, larvae and adults of acarids, has obvious synergistic effect and good control effect, reduces the dosage of the acarid killing composition, reduces the drug use frequency, greatly reduces the drug use cost, greatly reduces the influence on the environment, and is green and environment-friendly.

(2) The acaricidal composition provided by the invention is added with the modified carrier, the carrier is provided and calcined, the structure of the carrier is favorably expanded and perforated, the surface area of the carrier is greatly increased, and the primary carrier with excellent adsorption performance is obtained, plant powder can be obtained by drying and crushing the leaves of paris polyphylla, the leaves of iris tectorum and the leaves of oleander, the plant powder and the primary carrier are premixed, the plant powder and the primary carrier are uniformly mixed, polyethylene glycol, industrial gelatin and water are added, after uniform stirring and mixing, the plant powder can be well adsorbed by the primary carrier, the plant powder and the primary carrier are well combined together and stored in the primary carrier, wherein, iris tectorum has excellent repellent effect on panonychus citri, the aversion drug effect is lasting, the paris polyphylla and oleander have good poisoning effect on panonychus citri, and the poisoning effect is greatly improved and the drug effect is lasting through the compounding of the paris polyphylla and oleander, so that the modified carrier with good aversion and killing effect on the panonychus citri can be obtained, and the paris polyphylla, iris tectorum and oleander are all natural plant components, so that the environment-friendly modified carrier is green and environment-friendly, further the harm to the environment is reduced, in addition, the plant powder is stored in the modified carrier and is not easy to run off and decompose, and the drug effect durability is greatly improved.

Detailed Description

The present invention will be described in further detail with reference to specific examples, but the embodiments of the present invention are not limited thereto. All the raw materials and reagents used in the present invention are commercially available raw materials and reagents, unless otherwise specified. In the examples, the components are used in g and mL in parts by mass.

In one embodiment, the acaricidal composition comprises an active main agent and an auxiliary agent, wherein the active main agent comprises etoxazole and alkyl ethyl sulfonate, and the mass ratio of the etoxazole to the alkyl ethyl sulfonate is 1: 0.1 to 10.

The etoxazole has a contact killing effect, can effectively inhibit the embryo formation of mite eggs when contacting with mite eggs, and can also effectively inhibit the process from the molting of young mites to the adult mites, the etoxazole has a good control effect on the eggs of panonychus citri and the young mites, the etoxazole can also influence the reproductive function of female adult mites and has a good sterile effect on the female adult mites, however, the control effect of the etoxazole on the adult mites is general, the alkyl ethyl sulfonate can cause the palsy of adult mite pests and lead the adult mite pests to be dehydrated and killed, the thermal stability of the alkyl ethyl sulfonate is good, the pesticide effect is not influenced by temperature, the drug property stability of the prepared acaricidal composition can be ensured, the alkyl ethyl sulfonate has strong contact killing activity on the adult mites and the mite mites of the pests such as panonychus citri, tetranychus cinnabarinus, strawberry tetranychus urticae and the like, and the compound of the etoxazole and the alkyl ethyl sulfonate is adopted, and the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: when the concentration is 0.1-10, a specific acaricidal composition dosage form is prepared by an auxiliary agent, and in the embodiment, the weight of the active main agent accounts for 10-50% of the weight of the acaricidal composition. Therefore, the active auxiliary agent is moderate in dosage and optimal in insecticidal effect, and specifically can be prepared into one of a water suspending agent, a dispersible oil suspending agent, an aqueous emulsion, a microemulsion or missible oil.

In one embodiment, the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: 0.5 to 5. Therefore, the prepared acaricidal composition has better synergistic effect, the control effect is further improved, the using dosage of the acaricidal composition can be further reduced, the medication cost is further reduced, the influence on the environment is greatly reduced, and the acaricidal composition is green and environment-friendly. More preferably, the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: 0.3 to 3.

In one embodiment, the adjuvant includes at least one of a solvent, an emulsifier, a wetting agent, a stabilizer, a dispersant, a thickener, a pH adjuster, a defoamer, and an antifreeze. Therefore, by adopting different additives, the acaricidal composition with different formulations can be prepared according to specific production requirements, and specifically, the acaricidal composition can be prepared into an aqueous suspension agent, a dispersible oil suspension agent, an aqueous emulsion, a microemulsion or missible oil, so as to meet different use requirements.

In one embodiment, the solvent comprises at least one of water, mineral spirits S-200, xylene, trimethylbenzene, tetramethylbenzene, methylnaphthalene, methyl oleate, fatty acid methyl esters, pine-based oils, soybean oil, biodiesel, sec-butyl acetate, dimethyl carbonate, diesel, white oil, motor oil, and N-methylpyrrolidone. Thus, the compound can be used for dissolving and storing active main agents, namely etoxazole and alkyl ethyl sulfonate.

In one embodiment, the emulsifier comprises at least one of calcium dodecylbenzene sulfonate, fatty alcohol polyoxyethylene ether, triphenylethylphenol polyoxypropylene polyoxyethylene block polymer, dibenzylbiphenyl polyoxyethylene ether, phenethylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, phenethylphenol formaldehyde resin polyoxyethylene ether, phenethylphenol polyoxypropylene polyoxyethylene ether, alkylaryl polyoxypropylene polyoxyethylene ether, phenethylphenol formaldehyde resin polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether, natural fatty alcohol and ethylene oxide adduct, fatty acid and ethylene oxide condensate, polyoxyethylene fatty acid ester, and phenethylphenol polyoxyethylene ether polyoxypropylene ether. Therefore, the acaricide composition can play a role in emulsification, and is convenient to prepare into an aqueous emulsion, a microemulsion or an emulsifiable agent type acaricidal composition.

In one embodiment, the wetting agent comprises at least one of sodium butylnaphthalene sulfonate, sodium lauryl sulfate, fatty alcohol polyoxyethylene (6-7) ether, dioctyl sodium sulfosuccinate, Morwet EFW, alkyl naphthalene sulfonate, soapberry powder, and sodium lauryl sulfate. Therefore, the stability and the uniformity of the prepared acaricidal composition are improved.

In one embodiment, the dispersant comprises at least one of a polycarboxylate, a formaldehyde condensate of sodium methylnaphthalene sulfonate, sodium lignosulfonate, calcium lignosulfonate, p-methoxy fatty amidobenzenesulfonic acid, desugarized and fractionated sodium lignosulfonate, a sodium salt of a naphthalene sulfonic acid condensate, a sodium salt of an alkyl naphthalene sulfonic acid condensate, and a sulfuric acid alkylphenol polyoxyethylene ether formaldehyde condensate. Therefore, the acaricide composition can play a role in dispersion, and is convenient to prepare into an aqueous suspending agent or a dispersible oil suspending agent.

In one embodiment, the thickener comprises at least one of xanthan gum, magnesium aluminum silicate, bentonite, and white carbon black. Therefore, the system stability and the viscosity of the prepared acaricidal composition are improved.

In one embodiment, the pH adjusting agent comprises at least one of ammonium hydroxide, potassium hydroxide, sodium hydroxide, hydrochloric acid, acetic acid, citric acid, and phosphoric acid. Therefore, the method can be used for adjusting the pH value of the prepared acaricidal composition system, meets the specific requirements of medication and storage, and has better applicability.

In one embodiment, the stabilizer comprises at least one of dibutyl phthalate, hexamethylene diisocyanate, epoxidized soybean oil, epichlorohydrin, butyl hydroxyanisole, dibutyl hydroxytoluene, propyl gallate, and tert-butyl hydroquinone. Therefore, the stability and the uniformity of the prepared acaricidal composition are improved.

In one embodiment, the anti-foaming agent comprises at least one of a silicone-based compound, methanol, silicone oil, azone, and polydimethylsiloxane. Therefore, the anti-foaming function can be achieved, bubbles in the prepared acaricidal composition system are avoided, and the stability and the quality of the prepared acaricidal composition system are improved.

In one embodiment, the antifreeze agent comprises at least one of glycerol, ethylene glycol, propylene glycol, sorbitol, and polyethylene glycol. Therefore, the anti-freezing effect can be achieved, and the stability of the acaricidal composition system can be improved.

In one embodiment, a modified support is also included. In this embodiment, the modified carrier is treated by the following method: providing a carrier, calcining the carrier to obtain a first-stage carrier, providing the blades of paris polyphylla, the blades of iris tectorum and the blades of oleander, drying to make the blades of paris polyphylla, the blades of iris tectorum and the blades of oleander crisp, crushing to obtain plant powder, stirring and mixing the first-stage carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier.

In this embodiment, the carrier may include at least one of kaolin, diatomaceous earth, and attapulgite. Kaolin, diatomite and attapulgite all have good adsorption performance, the structure of the carrier is favorably expanded and perforated by providing the carrier and calcining the carrier, so that the surface area of the carrier is greatly increased, and a first-level carrier with good adsorption performance is obtained, plant powder can be obtained by drying and crushing the leaves of paris polyphylla, the leaves of iris tectorum and the leaves of oleander, the plant powder and the first-level carrier are premixed, the plant powder and the first-level carrier are uniformly mixed, polyethylene glycol, industrial gelatin and water are added, after stirring and mixing are uniform, the plant powder can be well adsorbed by the first-level carrier, the plant powder and the first-level carrier are well combined together, and the polyethylene glycol and the industrial gelatin are used as good adhesives to well store the plant powder in the first-level carrier, the iris is good in repelling effect on the panonychus citri, lasting in repelling effect, the paris polyphylla and oleander are good in poisoning effect on the panonychus citri, the poisoning effect is greatly improved and the pesticide effect is lasting through compounding of the paris polyphylla and oleander, so that the modified carrier with good repelling and killing effects on the panonychus citri can be obtained, the paris polyphylla, the iris tectorum and the oleander are all natural plant components, the environment is protected, harm to the environment is further reduced, in addition, plant powder is stored in the modified carrier, the plant powder is not prone to loss and decomposition, and the pesticide effect durability is greatly improved. It is worth mentioning that after the modified carrier is sprayed on the citrus leaves, the modified carrier may fall into the soil, and the modified carrier has good adsorbability, so that heavy metals in the soil can be adsorbed, thereby being beneficial to ensuring the normal growth of the citrus and improving the quality of the citrus.

In one embodiment, in the operation of calcining the carrier to obtain the primary carrier, the calcining temperature is controlled to be 180 ℃ to 230 ℃ and the calcining time is controlled to be 1h to 2 h. So, can avoid calcining the high temperature, cause the destruction to the structure of carrier, simultaneously, can also guarantee to obtain the one-level carrier of bulking and porogenesis, improve its adsorption efficiency greatly to be convenient for adsorb better and store the plant powder.

In one embodiment, in the providing and drying operation of the paris polyphylla leaves, the iris tectorum leaves and the oleander leaves, the drying temperature is controlled to be 38-48 ℃. Therefore, the drying temperature is moderate, the damage to the effective components of the paris polyphylla leaves, the iris tectorum leaves and the oleander leaves can be avoided, the drug properties of the paris polyphylla leaves, the iris tectorum leaves and the oleander leaves are maintained, and the preparation of the plant powder with good control effect is facilitated.

In one embodiment, the acaricidal composition comprises, by mass, 1-10 parts of etoxazole, 1-10 parts of alkyl ethyl sulfonate, 3-6 parts of modified carrier, 30-40 parts of solvent, 2-3 parts of wetting agent, 0.5-1 part of stabilizer, 2-3 parts of dispersant, 1-2 parts of thickener, 0.5-1 part of pH regulator, 1-2 parts of defoamer and 1-2 parts of antifreeze, wherein the solvent is water. In the embodiment, the acaricidal composition in the form of the aqueous suspension is prepared by mixing the above components in proportion and grinding in a ball mill for 2 to 3 hours so that the particle diameters are all less than 5 mm.

In one embodiment, the acaricidal composition comprises, by mass, 1-10 parts of etoxazole, 1-10 parts of alkyl ethyl sulfonate, 3-6 parts of modified carrier, 30-40 parts of solvent, 5-8 parts of emulsifier, 6-12 parts of wetting agent, 0.5-1 part of stabilizer, 1-2 parts of thickener, 0.5-1 part of pH regulator, 0.5-1 part of defoamer and 0.5-1 part of antifreeze, wherein the solvent is methyl oleate. In the embodiment, the acaricidal composition in the form of dispersible oil suspending agent is prepared by dissolving the above components in proportion into a uniform oil phase and mixing under high-speed stirring.

In one embodiment, the acaricidal composition comprises, by mass, 1-10 parts of etoxazole, 1-10 parts of alkyl ethyl sulfonate, 3-6 parts of modified carrier, 40-50 parts of solvent, 10-15 parts of emulsifier, 1-2 parts of wetting agent, 1-2 parts of stabilizer, 2-3 parts of thickener, 0.5-1 part of pH regulator, 0.5-1 part of defoamer and 0.5-1 part of antifreeze, wherein the solvent is water and trimethylbenzene. In the embodiment, the acaricidal composition in the form of aqueous emulsion is prepared by mixing the components in proportion and uniformly stirring.

In one embodiment, the acaricidal composition comprises, by mass, 1-10 parts of etoxazole, 1-10 parts of alkyl ethyl sulfonate, 3-6 parts of modified carrier, 40-50 parts of solvent, 4-6 parts of emulsifier, 2-3 parts of wetting agent, 1-2 parts of stabilizer, 1-2 parts of thickener, 0.5-1 part of pH regulator, 0.5-1 part of defoamer and 0.5-1 part of antifreeze, wherein the solvent is water and methylnaphthalene. In this embodiment, the miticidal composition in the form of a microemulsion is prepared by mixing the above components in a certain proportion and stirring them uniformly.

In one embodiment, the acaricidal composition comprises, by mass, 1-10 parts of etoxazole, 1-10 parts of alkyl ethyl sulfonate, 3-6 parts of modified carrier, 40-50 parts of solvent, 5-10 parts of dispersing agent, 1-2 parts of wetting agent, 1-2 parts of stabilizer, 1-2 parts of thickener, 0.5-1 part of pH regulator, 0.5-1 part of defoaming agent and 0.5-1 part of antifreezing agent, wherein the solvent is sec-butyl acetate. In the embodiment, the acaricidal composition in the form of emulsifiable concentrate is prepared by mixing the above components in proportion and uniformly stirring.

The invention also provides application of the acaricidal composition in controlling panonychus citri, which can comprehensively and effectively control mite eggs, larvae and imagoes of panonychus citri and has good control effect.

The following is a detailed description of the embodiments.

Examples 1 to 9

The acaricidal composition according to examples 1 to 9, wherein the acaricidal composition comprises the components shown in table 1 in parts by mass.

TABLE 1 miticidal compositions of examples 1-9

The formulations of examples 1-9 in table 1 were prepared according to the following procedure:

mixing etoxazole, alkyl ethyl sulfonate, a modified carrier, water, butyl sodium naphthalene sulfonate, epoxidized soybean oil, sodium lignin sulfonate, xanthan gum, potassium hydroxide, methanol and propylene glycol in proportion, and grinding for 2-3 h in a ball mill to ensure that the particle diameters are all below 5mm, thereby preparing the acaricidal composition in the form of water suspension.

The processing method of the modified carrier comprises the following steps: providing a carrier, wherein the carrier is a mixture of kaolin, diatomite and attapulgite, calcining the carrier, controlling the calcining temperature to be 200 ℃ and the calcining time to be 2h to obtain a primary carrier, providing a blade of paris polyphylla, a blade of iris tectorum and a blade of oleander, drying at 45 ℃ to make the blade of paris polyphylla, the blade of iris tectorum and the blade of oleander brittle, crushing to obtain plant powder, stirring and mixing the primary carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier.

Comparative example 1

Comparative example 1 is different from example 2 in that the acaricidal composition of comparative example 1 does not contain alkyl ethyl sulfonate, and etoxazole is used in an amount of 12 parts by mass, and other agent amounts and preparation methods are the same as those of example 2.

Comparative example 2

Comparative example 2 is different from example 2 in that the acaricidal composition of comparative example 2 does not contain etoxazole and the amount of the alkyl ethyl sulfonate is 12 parts by mass, and the amounts of other agents and the preparation method are the same as those of example 2.

Comparative example 3

Comparative example 3 differs from example 2 in that the acaricidal composition of comparative example 3 does not contain a modified carrier and the other agents are used in the same amounts and in the same manner as in example 2.

Comparative example 4

The difference between the comparative example 4 and the example 2 is that the modified carrier is treated by a different method, and the modified carrier of the comparative example 4 is treated by: providing a carrier, wherein the carrier is a mixture of kaolin, diatomite and attapulgite, calcining the carrier, controlling the calcining temperature to be 200 ℃ and the calcining time to be 2h to obtain a primary carrier, providing iris blades and oleander blades, drying at 45 ℃ to make the iris blades and the oleander blades brittle, crushing to obtain plant powder, stirring and mixing the primary carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier of the comparative example 4. Other amounts of reagents and preparation method were the same as in example 2.

Comparative example 5

The difference between the comparative example 5 and the example 2 is that the modified carrier is treated by a different method, and the modified carrier of the comparative example 5 is treated by: providing a carrier, wherein the carrier is a mixture of kaolin, diatomite and attapulgite, calcining the carrier, controlling the calcining temperature to be 200 ℃ and the calcining time to be 2h to obtain a primary carrier, providing the leaves of paris polyphylla and the leaves of oleander, drying at 45 ℃ to make the leaves of paris polyphylla and the leaves of oleander crisp, crushing to obtain plant powder, stirring and mixing the primary carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier of the comparative example 5. Other amounts of reagents and preparation method were the same as in example 2.

Comparative example 6

The difference between the comparative example 6 and the example 2 is that the modified carrier is treated by a different method, and the modified carrier of the comparative example 6 is treated by: providing a carrier, wherein the carrier is a mixture of kaolin, diatomite and attapulgite, calcining the carrier, controlling the calcining temperature to be 200 ℃ and the calcining time to be 2h to obtain a first-stage carrier, providing the leaves of paris polyphylla and the leaves of iris tectorum, drying at 45 ℃ to make the leaves of paris polyphylla and the leaves of iris tectorum crisp, crushing to obtain plant powder, stirring and mixing the first-stage carrier and the plant powder to obtain a premix, adding polyethylene glycol, industrial gelatin and water into the premix, stirring and mixing to obtain a mixture, and evaporating and drying the mixture to obtain the modified carrier of the comparative example 6. Other amounts of reagents and preparation method were the same as in example 2.

Comprehensive virulence determination

The acaricidal compositions prepared in examples 2, 4 to 9 and 1 to 6 are taken as examples to carry out comprehensive toxicity measurement.

The determination method comprises the following steps: referring to the method in NY/T1154.12-2008 standard, a glass sheet dipping method is adopted, red mites are taken as test targets, a double-sided adhesive tape is cut into 2cm in length and is attached to one end of a glass slide, then healthy red mites with consistent physiological states are selected, the back of the red mites is attached to the double-sided adhesive (no need to adhere mite feet, palpus and mouthparts), 30 heads of each piece of red mites are placed into a container padded with a wet sponge, a cover is covered, the red mites are placed under the temperature (25 +/-1) DEG C condition for 2 hours, dead and injured individuals are removed, 30 heads of each piece of red mites are complemented, a glass sheet with red mites is immersed into test liquid medicine, the glass sheet is slightly shaken, the red mites are taken out after being immersed for 5 seconds, redundant liquid medicine is removed through absorbent paper, the red mite tray padded with the wet sponge is placed into a white porcelain tray, the red mite tray is covered with a plastic film, and is finally placed at the temperature (25 +/-1) DEG C, the illumination period is L: incubate at (16: 8) h, set up 4 replicates per treatment, and use water with solvent as a blank.

Counting the test data after 3 days, calculating the death rate (%) and correcting the death rate (%), and if the control death rate is lower than 5%, not needing to be corrected; control mortality between 5% and 20% requires correction; control mortality was greater than 20%, and the test required redo.

Respectively establishing toxicity regression equations by taking the logarithmic value of the medicament concentration (mg/L) as an independent variable x and the probability value of the corrected mortality as a dependent variable y, and calculating LC50 and the co-toxicity coefficient of the single preparation and the mixture of the single preparation by adopting DPS software.

The synergistic effect evaluation method refers to a biological standard method NY/T1154.7-2006, and evaluates the synergistic effect of the mixed medicament according to a co-toxicity coefficient method (CTC), namely that the CTC is less than or equal to 80 and is antagonistic, the CTC is less than 80 and is additive, and the CTC is more than or equal to 120 and is synergistic. Wherein, the calculation formula is as follows:

the Theoretical Toxicity Index (TTI) of the mixed preparation is the toxicity index of the medicament A multiplied by 100 percent of the medicament A in the mixed preparation and the toxicity index of the medicament B multiplied by 100 percent of the medicament in the mixed preparation

TABLE 2 comprehensive virulence determination results

As can be seen from the data in the table 2, the acaricidal composition which is high in safety and has a co-toxicity coefficient greater than 120 can be obtained by compounding etoxazole and alkyl ethyl sulfonate as active ingredients of the acaricidal composition, wherein the weight ratio of etoxazole to alkyl ethyl sulfonate is 1: the composition shows obvious synergistic effect within the range of 0.1-10, wherein when the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: 1, the synergistic effect is most obvious.

Field test

The test method comprises the following steps: taking the acaricidal compositions prepared in the examples 2, 4-9 and 1-6 as examples, carrying out a field pesticide application test, setting a blank control group, carrying out no pesticide application treatment, adopting a spraying method for the pesticide in each example and each pair of the proportional pesticide, diluting the pesticide with water, and spraying the pesticide on citrus, wherein the spraying liquid amount per mu is 110L. In each example and each proportion, 10 treatment points are arranged, each treatment point is repeated for 4 times, the population base number of the panonychus citri is counted before application, 3 days after application and 15 days after application, the control effect is calculated, and the test result is shown in table 3.

TABLE 3 results of the field test

As can be seen from table 3, the control effect of etoxazole and alkyl ethyl sulfonate after being compounded is improved remarkably, wherein, as can be seen by comparing examples 2 and 4-9 with comparative examples 1-2, the pesticide effect after etoxazole and alkyl ethyl sulfonate are compounded is improved remarkably, the control effect of whole-claw citrus mite is improved remarkably, the safety is good, citrus grows normally, and no phytotoxicity phenomenon occurs, which indicates that citrus is safe, wherein, the control effect of example 2 is optimal, that is, when the mass ratio of etoxazole to alkyl ethyl sulfonate is 1: 1 hour, the control effect is optimal, the control effect is as high as 92.31 percent after 15 days of pesticide application, as can be seen by comparing the example 2 with the comparative example 3, the control effect can be further improved by adding the modified carrier under the condition of the same dosage and mass ratio of etoxazole and alkyl ethyl sulfonate, and as can be seen by comparing the example 2 with the comparative examples 4-6, the optimal panonychus citri control effect can be achieved after the carrier is compounded and combined with the leaves of paris polyphylla, the leaves of iris tectorum and the leaves of oleander, so that the acaricidal composition prepared by the example 2 has better pesticide effect and pesticide effect durability, and the control effect is further improved. In conclusion, the acaricidal composition disclosed by the invention has an obvious synergistic effect on panonychus citri, so that the germ control effect and the pesticide effect of the acaricidal composition are greatly improved, the control effect is obviously improved, the use amount of the acaricidal composition is favorably reduced, and the acaricidal composition is more environment-friendly.

The above embodiments are the best mode for carrying out the present invention, but the embodiments of the present invention are not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be regarded as equivalent substitutions and are included in the scope of the present invention.