Application of furan formic acid compound in preparation of animal feed additive
阅读说明：本技术 呋喃甲酸类化合物在制备动物饲料添加剂中的应用 (Application of furan formic acid compound in preparation of animal feed additive ) 是由 彭险峰 于 2021-07-30 设计创作，主要内容包括：本发明公开了呋喃甲酸类化合物在制备动物饲料添加剂中的应用。所述的呋喃甲酸类化合物如式I所示,其中,R-(1)、R-(2)和R-(3)分别独立为H或-COOH。本发明提供的呋喃甲酸类化合物或其饲料可接受的盐在动物养殖试验中对家畜、家禽和水产养殖动物的生产性能均体现了改善的效果。(The invention discloses an application of furancarboxylic acid compounds in preparing animal feed additives. The furoic acid compound is shown as a formula I, wherein R 1 、R 2 And R 3 Are each independently H or-COOH. The furan carboxylic acid compound or the acceptable salt of the feed thereof provided by the invention shows an improved effect on the production performance of livestock, poultry and aquaculture animals in animal breeding tests.)
1. The use of at least one of the furancarboxylic acid compounds of formula or a feed acceptable salt thereof, or a feed composition comprising the same, in the preparation of an animal feed additive;
wherein R is1、R2And R3Are each independently H or-COOH.
2. The use according to claim 1, wherein R is selected from the group consisting of furancarboxylic acids1And R3Is H, R2is-COOH; or R in the furan carboxylic acid compound1is-COOH, R2And R3Is H; or R in the furan carboxylic acid compound1And R3is-COOH, R2Is H.
3. Use according to claim 1 or 2, wherein the animal feed additive is a feed additive specific for livestock, poultry, aquaculture animals or pets in each growth stage.
4. Use according to claim 1 or 2, wherein the animal feed additive is a growth promoter.
5. The application of at least one furan formic acid compound shown as the following formula, or a feed acceptable salt thereof, or a feeding composition containing the furan formic acid compound in preparing animal feed;
wherein R is1、R2And R3Are each independently H or-COOH.
6. The use according to claim 5, wherein R is selected from the group consisting of furancarboxylic acids1And R3Is H, R2is-COOH; or R in the furan carboxylic acid compound1is-COOH, R2And R3Is H; or R in the furan carboxylic acid compound1And R3is-COOH, R2Is H.
7. Use according to claim 5 or 6, wherein the animal feed is a feed specific for livestock, poultry, aquaculture animals or pets in each growth stage.
8. The use of claim 5, wherein the animal feed further comprises additional animal feed ingredients.
9. The use of claim 5, wherein the animal feed further comprises an additional animal feed additive.
10. The use according to claim 9, wherein the additional animal feed additive is a nutritional animal feed additive, a non-nutritional animal feed additive or a pharmaceutical feed additive.
The technical field is as follows:
the invention relates to the field of animal feed, in particular to application of furan carboxylic acid compounds or feed acceptable salts thereof in preparing animal feed additives and animal feed.
Background art:
the feed additive is a small amount or trace substances added in the processes of processing, preparing and using the feed, and comprises nutritional feed additives and common feed additives. The general feed additive refers to a small amount or trace amount of substances which are added into the feed to ensure or improve the quality of the feed and improve the utilization rate of the feed. The general feed additives which are commonly used in the field at present and have the effects of efficiently and stably improving the feed utilization rate and improving the animal production performance mainly comprise high-dose copper agents, high-dose zinc agents, feed antibiotics, chemical synthetic antibacterial agents and the like, but the substances have large side effects in the breeding industry after long-term use. In order to ensure the health of animals and improve the production benefit of the breeding industry, the problem to be solved in the field is to find an effective, stable and safe new feed additive.
The invention content is as follows:
based on the application, the invention provides the application of the furan carboxylic acid compound or the acceptable salt of the feed thereof in preparing animal feed additives and animal feed.
On one hand, the application of at least one furan formic acid compound shown as the formula I or acceptable salt thereof in preparing animal feed additives and animal feed is as follows:
wherein R is1、R2And R3Are each independently H or-COOH.
In another aspect, the invention provides the use of a feed composition comprising at least one furoic acid compound represented by formula I or a feed acceptable salt thereof in the preparation of an animal feed additive or in the preparation of an animal feed.
In some embodiments, the animal feed further comprises an animal feed material.
In some embodiments, the animal feed further comprises an additional animal feed additive.
In some embodiments, the animal feed further comprises animal feed raw materials and additional animal feed additives.
In another aspect, the invention provides a method for improving the production performance of farmed animals.
In some embodiments, the methods comprise administering the furancarboxylic acid compounds provided herein or a feed acceptable salt thereof to a farm animal, e.g., adding the furancarboxylic acid compounds or a feed acceptable salt thereof to an animal feed, and then feeding the animal.
In some embodiments, the methods comprise administering to a farm animal a feed composition provided herein comprising the furancarboxylic acid compound or a feed acceptable salt thereof.
In some embodiments, the farm animal is a farm animal, a poultry, an aquaculture animal, or a pet animal at each growth stage.
In some embodiments, the farm animal is a young stage livestock or poultry.
In some embodiments, the livestock, such as pigs, are fed with the furancarboxylic acid compound, or a feed acceptable salt thereof, or a feeding composition containing the furancarboxylic acid compound in an amount of 500 to 5000ppm, preferably 2000 ppm.
In some technical schemes, the poultry, such as chickens, are added with the furan formic acid compound, or the feed acceptable salt thereof, or the feeding composition containing the furan formic acid compound in the animal feed, wherein the addition amount is 200-1000 ppm, and further preferably 100 ppm.
In some embodiments, the feed additive for the aquaculture animals, such as grass carp, comprises 100-600 ppm furan carboxylic acid compound, or a feed acceptable salt thereof, or a feed composition containing the furan carboxylic acid compound, preferably 500ppm furan carboxylic acid compound.
The invention has the beneficial effects that:
the furan carboxylic acid compound or the acceptable salt of the feed thereof or the feeding composition containing the furan carboxylic acid compound has an improved effect on the production performance of livestock, poultry and aquaculture animals in animal breeding experiments.
Any embodiment of any aspect of the invention may be combined with other embodiments as long as there is no conflict between them. Furthermore, in any embodiment of any aspect of the present invention, any technical feature may be applied to that technical feature in other embodiments as long as there is no contradiction therebetween.
The foregoing merely summarizes certain aspects of the invention and is not intended to be limiting. The foregoing and other aspects are more fully described below.
Further details of the invention are described.
Reference will now be made in detail to certain embodiments of the invention, examples of which are illustrated by the accompanying structural and chemical formulas. The invention is intended to cover alternatives, modifications and equivalents, which may be included within the scope of the invention as defined by the appended claims. Furthermore, certain features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment or in any suitable subcombination.
Definitions and/or general terms to which the invention relates.
The 'feed acceptable salt' is a salt formed by the furan carboxylic acid compound and organic base, inorganic base, organic acid or inorganic acid which are nontoxic to animals. By "feed acceptable" is meant that the substance or composition must be chemically or toxicologically compatible in connection with the constituent feed or the edible farmed animals.
The "significant change" under the influence factor investigation test conditions referred to in the present invention means "the change of the content of the test sample by 5% or more".
The term "animal" as used herein means a human or a cultured animal which is incapable of synthesizing organic matter from inorganic matter and capable of having life activities such as feeding, digestion, absorption, respiration, circulation, excretion, sensation, exercise, and reproduction by using only organic matter as a food. "farmed animals" include poultry, livestock, aquaculture animals, and other animals that are artificially reared to be legally caught, including pets, such as cats and dogs. The term "livestock" is, for example, any of pigs, cattle, horses, goats, sheep, deer, and many useful rodents. The term "poultry" is intended to include, for example, chickens, ducks, geese, quail, pigeons and the like. The term "aquaculture animal" includes, for example, fish, shrimp, turtles, and the like.
The invention relates to a feed additive, which is a small amount or trace substance added in the processes of processing, manufacturing and using feed and is divided into nutritional feed additives and common feed additives which are also called non-nutritional feed additives.
The feed is a product which is industrially processed and manufactured and is eaten by animals.
The composition refers to a compound set comprising one or more compounds as active ingredients.
The term "comprising" as used herein is open-ended, meaning that the meaning of the term is included, but not exclusive of other aspects.
The invention relates to application of furan formic acid compounds.
The invention provides a furan formic acid compound with a structure shown as a formula I or a salt acceptable by feed, which is applied to the preparation of an animal feed additive:
wherein R is1、R2And R3Are each independently H or-COOH.
In some embodiments, the furancarboxylic acid compound used in the preparation of the animal feed additive is preferably(chemical name: 2-Carboxylic acid Furan).
In some embodiments, the furancarboxylic acid compound used in the preparation of the animal feed additive is preferably(chemical name: 3-Carboxylic acid furan).
In some embodiments, the furancarboxylic acid compound used in the preparation of the animal feed additive is preferably(chemical name: 2, 4-dicarboxylic acid furan).
The furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing the growth promoter of animals in each growth stage, wherein the animals can be selected from livestock, poultry, aquaculture animals or pets in each growth stage.
Further, the domestic animals include, but are not limited to, pigs, cattle, sheep, horses, rabbits, mink, or donkeys, the poultry includes, but is not limited to, chickens, turkeys, ducks, geese, quail, or pigeons, the aquaculture animals include, but are not limited to, fish, shrimps, turtles, crabs, turtles, bullfrogs, eels, or loaches, and the pets include, but are not limited to, dogs or cats of each subspecies.
In one embodiment, the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing a feed additive capable of improving the growth performance of weaned pigs.
In another embodiment, the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing a feed additive capable of improving the growth performance of the medium pigs.
In another embodiment, the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing a feed additive capable of improving the growth performance of the chicks.
In another embodiment, the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing a feed additive capable of improving the growth performance of the fish.
The invention relates to a feeding composition.
A feeding composition comprises at least one of the furancarboxylic acid compounds or the feed acceptable salts thereof and a feeding auxiliary material, wherein the feeding auxiliary material is a feeding carrier, a diluent, an adjuvant, a solvent or a combination thereof.
The carrier is a feedable substance which can carry active ingredients, improve the dispersibility of the active ingredients and have good chemical stability and adsorbability, and is an organic carrier or an inorganic carrier. The organic carrier is a material containing much crude fiber, and comprises but is not limited to corn flour, corn cob powder, wheat bran, rice hull powder, defatted rice bran, unite bran, corn straw powder, peanut hull powder and the like. The inorganic carrier is mineral substance, mainly divided into calcium salt and silicon oxide, and is used for preparing microelement premix, including but not limited to calcium carbonate, silicate, vermiculite, zeolite, sepiolite, etc.
The diluent is organic diluent and inorganic diluent, which can separate trace components from each other and reduce the mutual reaction between active components to increase the stability of the active components without affecting the physical and chemical properties of the relevant substances. Organic diluents include, but are not limited to, corn flour, degermed corn flour, dextrose (glucose), sucrose, gluten-bearing semolina, parched soybean flour, wheat middling, corn gluten meal, and the like; inorganic diluents include, but are not limited to, limestone, monocalcium phosphate, shell powder, kaolin (kaolin), salt, and sodium sulfate.
The auxiliary agent is a wetting agent for inducing the inherent viscosity of the substance, a binding agent for binding the substance, a disintegrating agent for breaking the sheet-shaped substance into a plurality of fine particles, a retention aid for reducing the friction force between the particles or an anti-sticking agent for preventing the adhesion of the material, and comprises but is not limited to magnesium stearate, talcum powder, vegetable oil, magnesium lauryl sulfate, starch slurry, water, inorganic salt, dextrin, powdered sugar and the like.
The term "vehicle" as used herein refers to a solvent necessary to dissolve or disperse a solid, and includes, but is not limited to, water, ethanol, glycerol, and the like.
In some embodiments, the feed composition further comprises additional animal feed additives and/or animal feed materials.
The animal feed additive is a nutritional feed additive, a general feed additive or a pharmaceutical feed additive.
The nutritional feed additive is a small amount of or trace substances which are added into a compound feed to balance feed nutrients, improve the utilization rate of the feed and directly play a nutritional role on animals, and is amino acid, amino acid salt and analogues thereof, vitamin and retinoid, mineral elements and complex (chelate) compounds thereof, microbial enzyme preparation or nonprotein nitrogen.
The general feed additive is also called non-nutritive additive, and refers to some non-nutritive substances which are added into the feed for improving the utilization rate of the feed, ensuring the quality and quality of the feed and being beneficial to the health or metabolism of animals, and comprises growth promoters, insect repellent health care agents, seasoning and phagostimulants, feed modifying agents, feed conditioning agents, feed storage agents and Chinese herbal medicine additives.
In some embodiments, the composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof, further comprises one or more of a nutritional feed additive, a general feed additive, and a pharmaceutical feed additive.
In some embodiments, the animal feed material is a feed material such as grains and processed products thereof, oil seeds and processed products thereof, legume seeds and processed products thereof, tubers, root tubers and processed products thereof, other seeds, fruit products and processed products thereof, forage grass, roughage and processed products thereof, other plants, algae and processed products thereof, dairy products and by-products thereof, terrestrial animal products and by-products thereof, fish, other aquatic organisms and by-products thereof, minerals, microbial fermentation products and by-products, other feed materials, and the like.
Use of a feed composition.
The invention relates to the use of a feed composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof.
In some embodiments, the feed composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof is used in the preparation of an animal feed additive.
The animal feed additive prepared by the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is a livestock feed additive, a poultry feed additive, an aquaculture animal feed additive or a pet feed additive.
Specifically, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing a feed additive for livestock, wherein the livestock comprises, but is not limited to, pigs, cows, sheep, horses, rabbits, minks and the like in various growth stages.
Specifically, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing the feed additive for poultry, wherein the poultry comprises but is not limited to chickens, ducks, geese, pigeons and the like in various growth stages.
In particular, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing the feed additive of the aquaculture animals, wherein the aquaculture animals comprise but are not limited to fishes, shrimps, crabs, soft-shelled turtles, eels and the like in various growth stages.
In particular, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing a pet feed additive, and pets include, but are not limited to, artificially fed dogs or cats.
In some embodiments, the animal feed additive prepared with the composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof is a premix, a composite premix, an aqueous agent, or a granule.
In some embodiments, the feed composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof is used in the preparation of an animal feed.
The animal feed prepared by the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is livestock feed, poultry feed, aquaculture animal feed or pet feed.
Specifically, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing the feed for livestock, wherein the livestock comprises, but is not limited to, pigs, cows, sheep, horses, rabbits, martens and the like at various growth stages.
In particular, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing poultry feed, and the poultry comprises but is not limited to chickens, ducks, geese, pigeons and the like in various growth stages.
In particular, the feed composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof is used for preparing the feed of the aquaculture animals, wherein the aquaculture animals comprise but are not limited to fishes, shrimps, crabs, soft-shelled turtles, eels and the like in various growth stages.
In particular, the feed composition containing the furan carboxylic acid compound or the feed acceptable salt thereof is used for preparing pet feed, and the pet comprises but is not limited to artificially fed dogs or cats.
In some embodiments, the feed composition comprising the furancarboxylic acid compound or a feed acceptable salt thereof produces a feed that is a single feed, a concentrated feed, a compound feed, a premix, or a concentrate supplement.
Specifically, the compound feed is complete compound feed.
A method for improving the production performance of farmed animals.
In some feeding embodiments, feeding of a feed additive comprising the furancarboxylic acid compound or a feed acceptable salt thereof to an animal by a farmer in conjunction with the feed can significantly improve the production performance of the animal.
In some embodiments, the feed additive is a premix, a compound premix, granules or an aqueous solution, and is mixed with the animal feed to be eaten by the animals.
The animal is livestock, poultry, aquaculture animal or pet.
Specifically, the domestic animals include, but are not limited to, pigs, cows, sheep, horses, rabbits, minks, etc. at various stages of growth; the poultry includes but is not limited to chickens, ducks, geese, pigeons and the like in all growth stages; the aquaculture animals include, but are not limited to, fish, shrimp, crab, soft-shelled turtle, eel and the like in all growth stages; the pets include, but are not limited to, artificially raised dogs or cats.
In one embodiment, the farmer takes the feed additive containing the furan carboxylic acid compound or the feed acceptable salt thereof and the feed together with the feed to the weaned pigs, and the weight gain rate and the feed conversion rate of average daily gain of the weaned pigs are obviously improved.
In one embodiment, the farmer takes the feed additive containing the furan carboxylic acid compound or the salt acceptable in the feed and the feed together with the broiler chicken for eating, so that the feed conversion rate of the broiler chicken is obviously reduced.
In one embodiment, the farmer administers a feed additive comprising the furancarboxylic acid-based compound or a feed acceptable salt thereof to the fish with the feed.
In one embodiment, the farmer administers a feed additive comprising the furancarboxylic acid compound or a feed acceptable salt thereof to puppies with the feed.
In other feeding embodiments, feeding compositions comprising the furancarboxylic acid compounds or feed acceptable salts thereof to animals by farmers can significantly improve the production performance of the animals.
Optionally, the feeding composition is a feed additive premix, a feed additive compound premix, granules or an aqueous solution, and is taken together with the feed for animals.
In one embodiment, the feeding composition is a feed additive premix.
In one embodiment, the feeding composition is a feed additive compound premix.
Optionally, the feed composition is a concentrated feed, a compound premix or a concentrate supplement, and is directly fed to the animals as an animal feed.
In one embodiment, the feed composition is a complete formula feed.
Reference will now be made in detail to certain embodiments of the invention, examples of which are illustrated by the accompanying structural and chemical formulas. The invention is intended to cover alternatives, modifications and equivalents, which may be included within the scope of the invention as defined by the appended claims. Furthermore, certain features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment or in any suitable subcombination.
The specific implementation mode is as follows:
example 1 study of the Effect of Furanecarboxylic acid Compounds on the production Properties of weaned pigs
120 piglets of 65-day-old Du-growing three-element lean-type piglets with similar body weight are randomly divided into 4 treatment groups, each group is 3 in repetition, each half of a male pig and a female pig is 10 in each group. Pigsty and utensils were sterilized before the test. In the test period, the pigs are housed in different columns under the same feeding and management conditions in the same pigpen. During the test period, test pigs were fed free food and water 2 times a day. The test groups are shown in table 1, wherein group i is a control group to which only basal ration is given; test groups II and III were each dosed with a basal diet containing 2000ppm of the furancarboxylic acid compounds shown in Table 1. In the whole feeding process, other antioxidant ingredients and growth promoters are not additionally added in each test group. The test period was 28 days, and the performance of the test pigs was counted, as average daily feed intake (ADFI, g/d), average daily gain (ADG, g/d) and feed-to-meat ratio (FCR) per pig. The test results are expressed as "average values" as shown in table 1. From the results, it was found that the feed intake of the test pigs was not significantly affected when the test group to which the basic ration containing furancarboxylic acid compounds was given was compared with the control group, but the feed-meat ratio decreased by about 5.6% while the average daily gain was significantly increased.
TABLE 1 Furanoic acid Compounds Effect on piglet Productivity
Test article
Number of trials
ADFI
ADG
FCR
Group I
-
10*3
1187
450
2.637
Group II
2-Carboxylic acid furan
10*3
1274
512
2.489
Group III
3-Carboxylic acid furan
10*3
1240
498
2.491
Group IV
2, 4-dicarboxylic acid furan
10*3
1263
507
2.490
Experimental example 2 application study of Furanecarboxylic acid compounds in chicken feed
The test adopts single-factor random design, 480 three yellow-feathered broilers with the average weight of 50g and the age of 1 day and the similar weight are selected and randomly divided into 4 treatment groups, each group has 6 repetitions, each group has half of a male parent, and each repetition has 20 yellow-feathered broilers. The chicken coop and the appliances were sterilized before the test. In the test period, cage culture is carried out in the same chicken house under the same feeding management condition. The basic daily ration mainly comprises corn-soybean meal, and other antioxidant ingredients and growth promoters are not additionally added in the whole feeding process. The test groups are shown in table 2, wherein group i is a control group to which only basal ration is given; test groups II and III were each given a basal diet containing 1000ppm of the furans shown in Table 2. The test period is 20 days, and the test chicken freely drinks and takes food and feeds for 2 times a day. Weighing each repetition at 21 days of age (12 h without stopping water), counting the feed consumption of the test chickens, and calculating the average daily feed intake (ADFI, g/d), average daily gain (ADG, g/d) and Feed Conversion Ratio (FCR) of each test chicken.
The test results are expressed as "average values" and are shown in table 2. From the results, compared with the blank group, the effect of the feed intake of the experimental chicken on the control group and each test group is not obvious, but the average daily gain of the experimental chicken is obviously improved and the feed conversion ratio is obviously reduced.
TABLE 2 Furanoic acid compounds influence on broiler chicken productivity
Experimental example 3 application study of Furanecarboxylic acid compounds in fish feed
1) Test materials
The fish used for the test: the test fish is the live grass carp seeds with the same size and health in the same year in a large net cage (4X 2X 1.5 m)3) The culture is carried out for 4 weeks before the culture is carried out for formal culture tests, and the experimental system is a small floating net cage (the specification is 1.1 multiplied by 1.1 m)3) Each small net cage is provided with an inflation head, and 24 hours of air inflation is carried out every day. The small net cage and the temporary culture net cage are placed in a test field with a height of 3500m2In the pond, the depth of water in the pond is about 1.5mThe pond water is fully aerated bottom water. During the test, 240 grass carps hungry for 1 day are randomly divided into 3 groups, each group is provided with 4 repetitions, 20 fish are placed in each repetition, each repetition is taken as a unit, the weighed grass carps are placed in 12 net cages, and the grass carps are respectively fed with test feeds added with furan formic acid compounds.
Test feed: the test feeds were prepared according to the formulation of table 3, and 500ppm of furancarboxylic acid compounds were added to different test groups according to table 4. The feed raw materials are subjected to superfine grinding and then are prepared into buoyancy expanded feed with the particle size of 3mm by a Jiangsu shepherd expansion machine set, the mold stripping temperature is 130 ℃, 3% of soybean oil is sprayed outside by oil spraying equipment, and the feed is sealed and stored in a shade place for later use.
Table 3 grass carp feed formulation and chemical composition (% wt.) for testing
Composition of raw materials
Content (%)
Composition of raw materials
Content (%)
Fish meal
9.0
Soybean oil
3.0
Sausage casing powder
3.0
Phosphatide rapeseed meal
9.0
Bean pulp
12.0
Wheat gluten
4.0
Rapeseed meal
12.0
Blood cell powder
2.0
Monosodium glutamate protein
3.0
Vc-phosphoric acid ester
0.1
Wheat middling
12.6
Calcium dihydrogen phosphate
1.8
Flour
17.0
Choline chloride
0.2
Bentonite clay
0.70
Multi-dimensional
0.1
Rice bran
10.0
Micro-mineral premix
0.5
TABLE 4 growth promotion test grouping of Furanocarboxylic acid compounds
(2) Test method
And (3) test management: the experiment adopts artificial food restriction feeding, the feeding amount is adjusted once a week, the feeding level (according to the initial weight) of each group is completely consistent, the feeding is carried out twice a day (7:30 and 15:00), and the total feeding amount is 580 g/repeated experiment group. The test period was 8 weeks. The water quality is monitored regularly during the test period, the water temperature is 26.88 +/-3.08 ℃ and DO is kept in the whole cultivation process>5.0mg O L-1pH 7.8, ammonia nitrogen<0.50mgN L-1Nitrite nitrogen<0.05mg N L-1。
And (3) parameter statistics: during the test, after the feeding is stopped for 1d, the net cages are weighed integrally, and the weight gain rate (WG,%), the Feed Coefficient (FCR) and the survival rate (SR,%) are calculated. The calculation formula is as follows:
weight gain (WG,%) 100 × (average end weight-average initial weight)/average initial weight;
feed Factor (FCR) feed intake/fish body weight gain;
survival (SR,%) 100 x number of fish at the end of the test/number of fish at the beginning of the test.
(3) Test results
The results of the effect of furancarboxylic acid compounds on the productivity of grass carp are shown in Table 5. The results show that the test group added with the furan carboxylic acid compound is superior to a blank control group in weight gain and feed coefficient, has obvious growth promotion effect, can also obviously improve the survival rate of the grass carps, and has obvious oxygen deficiency resistance capability of the grass carps.
TABLE 5 Furanoic acid Compounds application test results in aquatic feed
Average initial weight (g)
Average final weight (g)
Weight gain (%)
(FCR)
SR(％)
Control group
251.25
574.64
133.15
1.56
55.00
Group I
249.81
586.87
134.96
1.48
82.50
Group II
246.56
589.33
138.98
1.48
83.75
The above-described embodiments are merely illustrative of some of the various ways in which the invention may be practiced and are intended to be covered by other embodiments. Accordingly, the embodiments of the present invention will be described by way of illustration, but not construed to limit the scope of the invention, and modifications made within the scope and spirit of the invention or equivalents added to the claims are possible.