阅读说明：本技术 一种抗尿酸功能性食品及其制备工艺 (Uric acid resistant functional food and preparation process thereof ) 是由 孙晓辉 于 2021-03-03 设计创作，主要内容包括：本发明涉及一种功能性食品及其制作方法,即一种抗尿酸功能性食品及其制备工艺。其原料原料包括山楂、石斛、金蝉花。制作方法：金蝉花,醋浸干燥后与石斛、山楂混合粉碎,120℃蒸汽0.18—0.25MPa的压强之下处理4—8秒,25—30℃发酵20—24小时,再用低温破壁机研磨成细粉,制成饮品或片剂或速溶冲剂。有益效果是：制成的功能性食品可增强人体尿酸排泄功能,且显效快,无毒副作用,可迅速缓解乃至消除痛风症状,并可为人体提供的多种营养成分,改善肝肾功能,提高人体的抗病能力,对于尿酸趋高及痛风患者具有预防、康复及辅助治疗的作用,对多种现有药品具有良好的增效作用,且口感柔和,食用方便,成本低廉,可望成为高尿酸人群及痛风患者所青睐的食疗用品。(The invention relates to a functional food and a preparation method thereof, in particular to an anti-uric acid functional food and a preparation process thereof. The raw materials comprise hawthorn, dendrobium and cicada fungus. The preparation method comprises the following steps: the cordyceps cicadae is soaked in vinegar, dried, mixed with the dendrobium and the hawthorn, crushed, treated for 4 to 8 seconds under the pressure of 0.18 to 0.25MPa of steam at the temperature of 120 ℃, fermented for 20 to 24 hours at the temperature of 25 to 30 ℃, ground into fine powder by a low-temperature wall breaking machine, and prepared into drinks or tablets or instant granules. The beneficial effects are that: the prepared functional food can enhance the function of excretion of uric acid of a human body, has quick effect, no toxic or side effect, can quickly relieve and even eliminate gout symptoms, can provide various nutrient components for the human body, improve the functions of liver and kidney, improve the disease resistance of the human body, has the effects of prevention, rehabilitation and auxiliary treatment for patients with high uric acid content and gout, has good synergistic effect on various existing medicines, has soft taste, convenient eating and low cost, and is expected to become a dietary therapy product favored by people with high uric acid content and patients with gout.)

1. An anti-uric acid functional food, which is characterized in that: the functional food comprises fructus crataegi, herba Dendrobii, and Cordyceps cicadae.

2. The anti-uric acid functional food according to claim 1, characterized in that: the functional food comprises the following raw materials in parts by weight: 1-3 parts of hawthorn, 2-4 parts of dendrobium nobile and 1-2 parts of cicada fungus.

3. The anti-uric acid functional food according to claim 2, characterized in that: the preparation method of the functional food comprises the following steps: the cordyceps cicadae is soaked in mature vinegar for 20-24 hours, dried, mixed with dendrobium and hawthorn and crushed into coarse powder, treated for 4-8 seconds under the pressure of 0.18-0.25 MPa of steam at 120 ℃, added with distilled water and yeast, mixed uniformly into a wet residue shape, fermented for 20-24 hours at 25-30 ℃, ground into fine powder with the granularity of more than 200 meshes by using a low-temperature wall breaking machine, and prepared into drinks or tablets or instant granules.

4. The anti-uric acid functional food according to claim 1, characterized in that: the Cordyceps cicadae is replaced by herba Zosterae Marinae and radix astragali.

5. The anti-uric acid functional food according to claim 4, characterized in that: 3-5 parts of kelp and 2-4 parts of astragalus.

6. The anti-uric acid functional food according to claim 2, characterized in that: 2-4 parts of chicory, 2-4 parts of gardenia jasminoides and 1-3 parts of kudzu root are added into the raw materials.

7. The anti-uric acid functional food according to claim 2, characterized in that: the raw materials are added with 2-4 parts of chicory, 2-4 parts of gardenia jasminoides, 1-3 parts of kudzu root and 1-3 parts of glabrous greenbrier rhizome.

8. The anti-uric acid functional food according to claim 2, characterized in that: the raw materials are added with 2-4 parts of chicory, 2-4 parts of gardenia jasminoides, 1-3 parts of kudzu root and 1-4 parts of rhodiola rosea.

9. The anti-uric acid functional food according to claim 2, characterized in that: 3-7 parts of eggplant stalk pedicel, 3-5 parts of celery root, 2-4 parts of bitter almond and 1-3 parts of honeysuckle are added into the raw materials.

10. The anti-uric acid functional food according to claim 6, 7, 8 or 9, characterized in that: the preparation method of the functional food comprises the following steps: soaking Cordyceps cicadae in old vinegar for 20-24 hr, drying, mixing with herba Dendrobii and fructus crataegi, pulverizing into coarse powder, treating with steam at 120 deg.C under 0.18-0.25 MPa for 4-8 s, adding distilled water and yeast, mixing to obtain wet residue, fermenting at 25-30 deg.C for 20-24 hr, and grinding into fine powder of 200 meshes or more with low temperature wall breaking machine; pulverizing other raw materials with low temperature wall breaking machine, adding water to submerge the raw materials, heating to boil, stopping heating, naturally cooling to 70-75 deg.C, maintaining the water evaporation to wet residue state, soaking in 95% ethanol for 1-1.5 hr, adding ultrasonic vibration, recovering ethanol, mixing the rest materials with Cordyceps cicadae, herba Dendrobii, and fructus crataegi, stirring, and processing with microwave processor to obtain beverage or tablet or instant granule.

Technical Field

The invention relates to a functional food and a preparation method thereof, in particular to an anti-uric acid functional food and a preparation process thereof.

Background

Gout is an inflammatory disease induced by mono-natriuretic urate crystals, and hyperuricemia can be caused by long-term purine metabolism activity, purine intake excess or uric acid excretion disorder. Long-term hyperuricemia can cause deposition of urate crystals in joints and surrounding soft tissues, and further repeated acute joint and soft tissue inflammation, tophus deposition, chronic arthritis and joint damage occur. Hyperuricemia also affects the kidney, causing chronic interstitial nephritis and urate calculi formation. The early active uric acid lowering treatment of gout patients can delay or prevent organ damage. At present, gout treatment mainly comprises drug therapy and dietary therapy, and the drugs comprise western medicines and traditional Chinese medicines. Western medicines such as non-steroidal anti-inflammatory drug, colchicine, and glucocorticoid used in acute stage are provided. Allopurinol, febuxostat, benzbromarone, probenecid and other uric acid reducing medicines are adopted in the chronic stage. Western medicines have quick response but strong toxic and side effects and are not suitable for long-term use. The traditional Chinese medicine has various varieties, but the traditional Chinese medicine takes effect too slowly, hardly has effect on gout in the acute attack stage, is poor in taste and painful to take in most of the gout, and also has some toxic and side effects. The food therapy adopts the materials which are approved by the state and have homology of medicine and food, and has no toxic and side effect. Particularly, some medicinal tea drinks, such as famous chicory gardenia tea and the like, can supplement water and promote urination, promote excretion of uric acid and have good mouthfeel, so the medicinal tea drink is suitable for long-term administration. However, the existing food therapy has the problem of slow effect, even slower than traditional Chinese medicine, thereby limiting the popularization of food therapy. If the obvious effect process of food therapy can be accelerated, the food therapy becomes a main means for resisting gout, thereby bringing good news to gout patients and even the whole society.

Disclosure of Invention

The invention aims to provide a dietotherapy product which has good treatment or auxiliary treatment effect on gout, quick response, convenient use, low cost and no toxic or side effect, and a preparation method thereof.

The above purpose is realized by the following technical scheme: provides a functional food for resisting uric acid, which is characterized in that: the functional food comprises fructus crataegi, herba Dendrobii, and Cordyceps cicadae.

The functional food comprises the following raw materials in parts by weight: 1-3 parts of hawthorn, 2-4 parts of dendrobium nobile and 1-2 parts of cicada fungus.

The preparation method of the functional food comprises the following steps: the cordyceps cicadae is soaked in mature vinegar for 20-24 hours, dried, mixed with dendrobium and hawthorn and crushed into coarse powder, treated for 4-8 seconds under the pressure of 0.18-0.25 MPa of steam at 120 ℃, added with distilled water and yeast, mixed uniformly into a wet residue shape, fermented for 20-24 hours at 25-30 ℃, ground into fine powder with the granularity of more than 200 meshes by using a low-temperature wall breaking machine, and prepared into drinks or tablets or instant granules.

The Cordyceps cicadae is replaced by herba Zosterae Marinae and radix astragali.

2-4 parts of chicory, 2-4 parts of gardenia jasminoides and 1-3 parts of kudzu root are added into the raw materials.

The raw materials are added with 2-4 parts of chicory, 2-4 parts of gardenia jasminoides, 1-3 parts of kudzu root and 1-3 parts of glabrous greenbrier rhizome.

The raw materials are added with 2-4 parts of chicory, 2-4 parts of gardenia jasminoides, 1-3 parts of kudzu root and 1-4 parts of rhodiola rosea.

3-7 parts of eggplant stalk pedicel, 3-5 parts of celery root, 2-4 parts of bitter almond and 1-3 parts of honeysuckle are added into the raw materials.

The preparation method of the functional food comprises the following steps: soaking Cordyceps cicadae in old vinegar for 20-24 hr, drying, mixing with herba Dendrobii and fructus crataegi, pulverizing into coarse powder, treating with steam at 120 deg.C under 0.18-0.25 MPa for 4-8 s, adding distilled water and yeast, mixing to obtain wet residue, fermenting at 25-30 deg.C for 20-24 hr, and grinding into fine powder of 200 meshes or more with low temperature wall breaking machine; pulverizing other raw materials with low temperature wall breaking machine, adding water to submerge the raw materials, heating to boil, stopping heating, naturally cooling to 70-75 deg.C, maintaining the water evaporation to wet residue state, soaking in 95% ethanol for 1-1.5 hr, adding ultrasonic vibration, recovering ethanol, mixing the rest materials with Cordyceps cicadae, herba Dendrobii, and fructus crataegi, stirring, and processing with microwave processor to obtain beverage or tablet or instant granule.

The invention has the beneficial effects that: the prepared functional food can enhance the function of human body for excretion of uric acid, has quick effect, no toxic or side effect, can quickly relieve and even eliminate gout symptoms, can provide various nutrient components for human bodies, improves the functions of liver and kidney and microcirculation level, greatly improves the disease resistance of human bodies, has the effects of prevention, rehabilitation and auxiliary treatment for patients with high uric acid and gout, has good synergistic effect on various existing medicines, has soft taste, is convenient to eat and low in cost, and can be expected to become a preferred diet therapy product for people with high uric acid and patients with gout.

Detailed Description

The first embodiment: the functional food with the effect of preventing and treating gout is provided, and is characterized in that: the functional food comprises fructus crataegi, herba Dendrobii, and Cordyceps cicadae. The weight ratio is as follows: 1-3 parts of hawthorn, 2-4 parts of dendrobium nobile and 1-2 parts of cicada fungus. Preferably 3 parts of hawthorn, 3 parts of dendrobium and 2 parts of cicada fungus. Preparing the beverage by adopting a conventional processing mode, such as: pulverizing, decocting in water, concentrating, and making into various dosage forms. The administration method is tea drink. The medicine is taken 3-5 times a day after being infused into 500ml of liquid 15-20 g for an adult each time.

Fructus crataegi is dried mature fruit of Crataegus Pinnatifida Bge of Crataegus of Rosaceae. Has effects of resolving food stagnation, activating qi-flowing and removing blood stasis. It can be used for treating food stagnation, dysentery, abdominal pain, hernia pain, stagnation of blood, chest pain, dysmenorrhea, etc.

The stem and leaf of Dendrobium nobile (Brandrebium nobile) in Orchidaceae has effects of resisting oxidation, lowering blood sugar, delaying aging, dilating blood vessel, lowering blood viscosity, reducing blood lipid, and preventing thrombosis.

Cicada fungus, english name: vegetable cicada, also called Jinchan grass, is also called silkworm chrysalis, cicada flower, worm flower, cicada shell, flower and cicada grass. The root of the cicada fungus is the larva of the cicada pupa or the cicada, and the fungus grows from the head of a single or 2-3 cicada larvae. Research shows that the cordyceps cicadae has multiple functions of improving immunity, resisting fatigue, protecting kidney, improving sleep, resisting tumor, protecting liver, resisting radiation, improving eyesight and the like. The artificially cultured Cordyceps sobolifera contains mannitol, polysaccharide, amino acids, cordycepin and adenosine, and is similar to natural Cordyceps. Therefore, the cordyceps sobolifera can be used as a substitute of cordyceps sinensis to achieve the purpose of nourishing and preserving health. However, the artificially cultured cordyceps sobolifera does not contain toxic heavy metals such as arsenic, mercury, lead and the like, so that the safety of the cordyceps sobolifera is higher than that of natural cordyceps sinensis.

In the formula, the raw materials comprise hawthorn, dendrobium and cicada fungus, and the inclusion has two meanings according to the specification of national languages. One is "only these three materials". The second is "other raw materials", which mainly refers to the raw materials involved in the following examples.

The research process of the formula is briefly described as follows: in the clinic of gout, the treatment of gout mainly comprises drug treatment and food therapy. The medicine comprises western medicine and Chinese medicine. Western medicines have quick response, can relieve pain in 1 to 2 days, but have strong toxic and side effects, are not suitable for long-term use and cannot radically cure the diseases. The traditional Chinese medicine has slow effect, poor taste and toxic and side effects, and can not be taken for a long time. The food therapy has good taste, no toxic or side effect, is beneficial to the body, can be taken for a long time, but also has the defect of slow effect. Therefore, it is desirable to find a fast acting food therapy product. In 2013-2015, the effect taking time of the formula is found to be obviously faster than that of a similar diet therapy formula in clinic, and the formula is slower than that of western medicines, but still has important significance and arouses attention of people. Therefore, the medical records of the past years are analyzed and studied.

The data sorting method comprises the following steps: 90 male cases (because gout is mostly male), are divided into three groups, namely an experimental group, a control group 1 and a control group 2, and each group has 30 cases. The experimental group adopts the medicinal granules prepared by the formula, and the control group 1 adopts a commercially available product, namely the chicory and gardenia tea, and the formula comprises the chicory, the mulberry leaf, the kudzu root, the gardenia, the lily and the cassia seed. The control group 2 mainly used the western medicine probenecid. According to the current standard, the uric acid value of a male adult is 300-350 mu mol/L which is a normal value, the uric acid value of the male adult is spontaneously developed when the blood uric acid value is above 420 mu mol/L, and the blood uric acid value of a clinical patient is about 500 mu mol/L mostly. The time from the start of administration to the time at which the pain was reduced and the uric acid level began to decline is shown in the table. The relief time shown in the table is a time until the uric acid level becomes stable at 420. mu. mol/L or less and pain substantially disappears after administration.

The statistical results show that: the western medicine has the shortest effective time, and the chicory gardenia tea has the longest effect in the formula of the group. Although the effective time of the prescription is longer than that of western medicines, the prescription is not regarded as important because of poor radical cure effect and toxic and side effects. Although the relieving time of the formula is longer than that of chicory gardenia tea, the gout is attacked more quickly, and the pain is quickly relieved. Therefore, the formula has important clinical significance.

The second embodiment: in order to further shorten the effective time of the formula, various explorations are carried out on the manufacturing process, and various process routes which are feasible in ratio are screened. The example only introduces a processing technology with better effect: the cordyceps cicadae is soaked in mature vinegar for 20-24 hours, dried, mixed with dendrobium and hawthorn and crushed into coarse powder, treated for 4-8 seconds under the pressure of 0.18-0.25 MPa of steam at 120 ℃, added with distilled water and yeast, mixed uniformly into a wet residue shape, fermented for 20-24 hours at 25-30 ℃, ground into fine powder with the granularity of more than 200 meshes by using a low-temperature wall breaking machine, and prepared into drinks or tablets or instant granules.

The technical key point of the process is that the raw materials are fully refined on the premise of keeping the effective components as much as possible. The acetic acid treatment is very beneficial to the dissolution of the active ingredients of the cordyceps sinensis. The cordyceps, the dendrobium and the hawthorn are crushed together and mixed more uniformly. The high-temperature treatment is carried out quickly under the pressure of 2 atmospheres, so that the sterilization and activation can be realized, and the damage of high temperature to effective components can be prevented. Effective components can be further separated by fermentation, and cell walls are broken by low-temperature grinding, so that the effective components can be absorbed and utilized by human bodies more conveniently.

The processed product, compared to the first example, gave the following results:

the control group is a numerical value with reference to the formulation of the first example. The experimental group is the product made by the process of this example. Therefore, the effective time and the release time of the new processing technology are both greatly shortened, which indicates that the new processing technology is feasible.

Third embodiment: on the basis of the previous embodiment, the method is further improved, the main raw materials of the chicory and gardenia tea, namely chicory, gardenia jasminoides and kudzu vine root are added into the formula to form a new formula: 1-3 parts of hawthorn, 2-4 parts of dendrobium, 1-2 parts of cordyceps sobolifera, 2-4 parts of chicory, 2-4 parts of gardenia jasminoides ellis and 1-3 parts of kudzu root. Preferably 2 parts of hawthorn, 2 parts of dendrobium, 2 parts of cicada fungus, 3 parts of chicory, 2 parts of gardenia jasminoides and 2 parts of kudzu root.

Chicory (Cichorium intybus L.), also known as Sonchus arvensis, Carsini arvensis, Sonchus arvensis, Oldham, coffee radish, Compositae, Cichorium, perennial herbs. The aerial parts and roots of the plants can be used for medicine, the traditional Chinese medicines are chicory and chicory root respectively, and the traditional Chinese medicine has the effects of clearing away heat and toxic materials, inducing diuresis to reduce edema, invigorating stomach and the like. Is a plant used as both medicine and food, and has its leaf capable of being used as raw material, root containing inulin and aromatic substance, and capable of being used as substitute coffee for promoting digestive organ activity of human body.

Cape jasmine, another name: gardenia (with the scientific name of Gardenia jasminoides Ellis), also called Gardenia jasminoides, Gardenia jasminoides and bufo gargarizans are fruits of Gardenia jasminoides in the family of Rubiaceae, are traditional Chinese medicines, and have the effects of protecting liver, benefiting gallbladder, reducing blood pressure, tranquilizing, stopping bleeding, reducing swelling and the like. The traditional Chinese medicine is commonly used for treating icteric hepatitis, sprain and contusion, hypertension, diabetes and other diseases in clinic, and belongs to the first batch of medicinal and edible raw materials issued by the Ministry of health.

Kudzu root, english name: radix Puerarae, Lobed Kudzuvine Root. Is dried root of Pueraria lobata Ohwi of Leguminosae, commonly known as Pueraria lobata Ohwi. Sweet, pungent and cool. Has the functions of expelling pathogenic factors from muscles, allaying fever, promoting eruption, promoting the production of body fluid to quench thirst, invigorating yang and stopping diarrhea. It is commonly indicated for exterior syndrome with fever, stiffness and pain of neck and back, measles without adequate eruption, thirst due to fever, diabetes due to yin deficiency, dysentery due to heat-purging and diarrhea due to spleen deficiency.

The following processing technology is preferred: soaking Cordyceps cicadae in old vinegar for 20-24 hr, drying, mixing with herba Dendrobii and fructus crataegi, pulverizing into coarse powder, treating with steam at 120 deg.C under 0.18-0.25 MPa for 4-8 s, adding distilled water and yeast, mixing to obtain wet residue, fermenting at 25-30 deg.C for 20-24 hr, and grinding into fine powder of 200 meshes or more with low temperature wall breaking machine; pulverizing other raw materials by a low-temperature wall breaking machine, adding water to submerge the raw materials, heating to boil, stopping heating, naturally cooling to 70-75 ℃, maintaining the water evaporation to a wet residue state, and adding 95% ethanol for soaking for 1-1.5 hours. Mixing the above materials, and making into beverage, tablet or instant granule.

The above process is the preferred method of processing through a number of experiments. Wherein, the cicada fungus is soaked in mature vinegar to dissolve out the effective components, which is convenient for human body to absorb and utilize. The coarse powder of the dendrobium and the hawthorn is subjected to steam pressurization and rapid treatment, so that disinfection and sterilization can be realized, decomposition and modification of effective ingredients can be avoided, the effective ingredients can be fully separated out through fermentation, and the permeability of the dendrobium and the hawthorn can be greatly enhanced through low-temperature wall breaking. Other raw materials are also subjected to short-time high-heat treatment, active ingredients are preserved, and after the active ingredients are dissolved by ethanol, the ethanol is not required to be further extracted, and only the ethanol is recovered, so that the cost can be reduced, and the active ingredients are highly dissolved and are convenient to absorb and utilize.

The results of the statistical comparison are shown in the following table:

in the table, the experimental groups are the formulation data of this example; control 1 is the second example experimental group data; control 2 is data from the first example of chicory gardenia tea. Control group 3 western medicines are data of the first embodiment. As can be seen from the data, the effect-displaying time and the buffering time of the formula are further shortened.

The fourth embodiment: further improvements are made on the basis of the foregoing embodiments. The main raw materials of the chicory and gardenia tea, namely chicory, gardenia jasminoides, kudzu root and glabrous greenbrier rhizome are added into the formula to form a new formula: 1-3 parts of hawthorn, 2-4 parts of dendrobium, 1-2 parts of cordyceps sobolifera, 2-4 parts of chicory, 2-4 parts of gardenia jasminoides, 1-3 parts of radix puerariae and 1-3 parts of rhizoma smilacis glabrae. Preferably 2 parts of hawthorn, 2 parts of dendrobium, 2 parts of cicada fungus, 3 parts of chicory, 2 parts of gardenia jasminoides ellis, 2 parts of kudzu root and 1 part of glabrous greenbrier rhizome.

Glabrous greenbrier rhizome, english name: glabrous Greenbrier Rhizome is perennial evergreen climbing shrub of Liliaceae, and the part used as medicine is dried Rhizome. The functions are as follows: detoxify and dissipate nodulation, dispel wind and dredge collaterals, remove dampness and discharge turbidity. It can be used for treating syphilis, pharyngitis, carbuncle, cellulitis, malignant boil, scrofula, carcinoma, spasm and pain of muscles and bones, edema, stranguria with turbid urine, diarrhea, tinea pedis, eczema, scabies, and mercurial poisoning.

The following processing technology is preferred: soaking Cordyceps cicadae in old vinegar for 20-24 hr, drying, mixing with herba Dendrobii and fructus crataegi, pulverizing into coarse powder, treating with steam at 120 deg.C under 0.18-0.25 MPa for 4-8 s, adding distilled water and yeast, mixing to obtain wet residue, fermenting at 25-30 deg.C for 20-24 hr, and grinding into fine powder of 200 meshes or more with low temperature wall breaking machine; pulverizing other raw materials with low temperature wall breaking machine, adding water, heating to boil, stopping heating, naturally cooling to 70-75 deg.C, maintaining water evaporation to wet residue state, soaking in 95% ethanol for 1-1.5 hr, and making into beverage, tablet or instant granule.

The above process is the preferred method of processing through a number of experiments. Wherein, the cicada fungus is soaked in mature vinegar to dissolve out the effective components, which is convenient for human body to absorb and utilize. The coarse powder of the dendrobium and the hawthorn is subjected to steam pressurization and rapid treatment, so that disinfection and sterilization can be realized, decomposition and modification of effective ingredients can be avoided, the effective ingredients can be fully separated out through fermentation, and the permeability of the dendrobium and the hawthorn can be greatly enhanced through low-temperature wall breaking. Other raw materials are also subjected to short-time high-heat treatment, active ingredients are preserved, and after the active ingredients are dissolved by ethanol, the ethanol is not required to be further extracted, and only the ethanol is recovered, so that the cost can be reduced, and the active ingredients are highly dissolved and are convenient to absorb and utilize.

The results of the statistical comparison are shown in the following table:

in the table, the experimental groups are the formulation data of this example; control 1 is the second example experimental group data; the chicory gardenia tea and the western medicines are data of the first embodiment. It can be seen from the above data that the development time and the buffering time of the improved formulation and processing method are further shortened.

Fifth embodiment: on the basis of the third embodiment, the rhodiola root is used for replacing the glabrous greenbrier rhizome to form a new formula: 1-3 parts of hawthorn, 2-4 parts of dendrobium, 1-2 parts of cordyceps sobolifera, 2-4 parts of chicory, 2-4 parts of gardenia jasminoides, 1-3 parts of radix puerariae and 1-4 parts of rhodiola rosea. Preferably 2 parts of hawthorn, 2 parts of dendrobium, 2 parts of cicada fungus, 3 parts of chicory, 2 parts of gardenia jasminoides ellis, 2 parts of kudzu root and 3 parts of rhodiola rosea.

Rhodiola rosea (Sedum rosea) is a rhizome of rhodiola rosea Rholioa rosea limn. or rhodiola crenulata R.euryphylla (Frod.) S.H.Fu. of Crassulaceae. Has the effects of invigorating spleen, invigorating qi, clearing lung-heat, relieving cough, promoting blood circulation, and removing blood stasis. It is used for treating spleen qi deficiency syndrome, lung yin deficiency syndrome, and cough due to lung heat.

The following processing technology is preferred: soaking Cordyceps cicadae in old vinegar for 20-24 hr, drying, mixing with herba Dendrobii and fructus crataegi, pulverizing into coarse powder, treating with steam at 120 deg.C under 0.18-0.25 MPa for 4-8 s, adding distilled water and yeast, mixing to obtain wet residue, fermenting at 25-30 deg.C for 20-24 hr, and grinding into fine powder of 200 meshes or more with low temperature wall breaking machine; pulverizing other raw materials with a low-temperature wall breaking machine below-20 deg.C, adding water, heating, naturally cooling to 70-75 deg.C, maintaining the water evaporation to wet residue state, soaking in 95% ethanol for 1-1.5 hr, adding ultrasonic wave above 40KHz, shaking, recovering ethanol, mixing with Cordyceps cicadae flower, herba Dendrobii, and fructus crataegi, stirring, and making into beverage, tablet or instant granule with 3000-5000 MHZ microwave treatment.

The above process is the preferred method of processing through a number of experiments. Wherein, the cicada fungus is soaked in mature vinegar to dissolve out the effective components, which is convenient for human body to absorb and utilize. The coarse powder of dendrobium and hawthorn is subjected to steam pressurization and rapid treatment, so that disinfection and sterilization can be realized, decomposition and modification of effective components can be avoided, the effective components can be fully separated out through fermentation, and the coarse powder can be prepared into fine powder with super-strong permeability through low-temperature wall breaking, so that the effect time is greatly shortened. Other raw materials are subjected to low-temperature wall breaking and short-time high-temperature purification, effective components are still fully dissolved out even though the raw materials are not extracted after being soaked in ethanol, then the raw materials are further subjected to ultrasonic treatment for cracking and refining, and the raw materials are mixed and then subjected to microwave treatment, so that macromolecular groups can be further opened, particles are miniaturized, and the effect time of a patient after taking the composition is greatly shortened.

The results of the statistical comparison are shown in the following table:

in the table, data for this example formulation of experimental groups; control 1 is data of the second example experimental group; control 2 is data for the first example of chicory gardenia tea; control 3 is the data for the first embodiment of the western medicine. The data show that the effect of the rhodiola rosea is increased by being similar to that of the smilax glabra. Meanwhile, the effects of strengthening spleen and replenishing qi, clearing lung and relieving cough, and activating blood and dissolving stasis are enhanced, and the testee feels good.

Sixth embodiment: the eggplant stalk, the celery root, the bitter apricot seed and the honeysuckle are added on the basis of the first embodiment. Forming a new formula: 1-3 parts of hawthorn, 2-4 parts of dendrobium, 1-2 parts of cicada fungus, 3-7 parts of eggplant stalk, 3-5 parts of celery root, 2-4 parts of bitter almond and 1-3 parts of honeysuckle. The preferable raw materials comprise the following components in parts by weight: 2 parts of hawthorn, 2 parts of dendrobium, 2 parts of cicada fungus, 5 parts of eggplant stalk, 4 parts of celery root, 3 parts of bitter almond and 2 parts of honeysuckle.

Eggplant calyx, also called eggplant calyx and eggplant calyx, is the persistent calyx of green plant eggplant (scientific name: Solanum melongena L.) of Solanum of Solanaceae, can be eaten, is also a Chinese herbal medicine, has the effects of dissipating blood, promoting urination and dispelling toxicity, and is commonly used for treating intestinal wind and bleeding, carbuncle sore, aphtha and toothache.

Celery root is root of Otnanthe Ljavanica (B.) DC (scientific name: apex graveolens) or 0.5 times weight part of Parsley nudum (Latin name: Pternopetalum nudiflorum (de Boiss.) hand-d. -. Mazz. [ Cryptotaeniopsis nudiflorum de Boiss.) of Umbelliferae. Celery root has the functions of lowering blood pressure, lowering blood sugar, tranquilizing and allaying excitement. In addition, celery root can promote the metabolism and discharge of water, has the function of diuresis, and also contains cellulose, and has the functions of promoting digestion, expelling toxin, relaxing bowels and preventing intestinal cancer.

Bitter apricot seeds, also called almond, are used. Dried mature seeds of Prunus armeniaca L.var.ansu Maxim, Prunus sibirica L.of the Rosaceae family, Prunus armeniaca Koehne (Maxim.) mandshurica or Prunus armeniaca L.of the northeast China. Collecting mature fruits in summer, removing pulp and nucleocapsid, taking out seeds, and drying in the sun.

Honeysuckle flower, Lonicera japonica (Lonicera japonica), is a dried bud or flower with early blossoming flower of Lonicera of Caprifoliaceae and plants of the same genus. Good medicine for clearing heat and detoxicating. It is sweet and cold in nature and fragrant, sweet and cold in nature and clearing heat without hurting stomach, and the fragrance is thorough and can eliminate pathogens. It can disperse wind-heat and clear blood toxin, and has obvious effect on treating various heat diseases, such as fever, eruption, macula, sore and carbuncle due to heat toxin, sore throat, etc.

And the following processing technology is preferred: soaking Cordyceps cicadae in old vinegar for 20-24 hr, drying, mixing with herba Dendrobii and fructus crataegi, pulverizing into coarse powder, treating with steam at 120 deg.C under 0.18-0.25 MPa for 4-8 s, adding distilled water and yeast, mixing to obtain wet residue, fermenting at 25-30 deg.C for 20-24 hr, and grinding into fine powder of 200 meshes or more with low temperature wall breaking machine; pulverizing other raw materials with low temperature wall breaking machine, adding water to submerge the raw materials, heating to boil, stopping heating, naturally cooling to 70-75 deg.C, maintaining the water evaporation to wet residue state, soaking in 95% ethanol for 1-1.5 hr, adding 40KHz above ultrasonic wave, shaking, recovering ethanol, mixing with Cordyceps cicadae, herba Dendrobii, and fructus crataegi, stirring, and microwave treating at 3000-5000 MHZ to obtain beverage, tablet or instant granule.

The results of the statistical comparison are shown in the following table:

the experimental groups in the table are the formulation data of this example; control 1 is data of the second example experimental group; the data from the first example were used for the remaining two control groups. Therefore, the composition of the embodiment has little difference from the previous embodiment in the effect time, and the remission time is further shortened, which shows that the later effect is very good.

The seventh embodiment: because of shortage of cordyceps cicadae medicinal herbs, the cost is high. Therefore, a variety of substitutes have been found through extensive research. Wherein, various cordyceps cultivated artificially in various places at present can be used as a substitute raw material. This example only describes a scheme of using kelp and astragalus root instead of cordyceps sobolifera.

Laminaria japonica, Laminariaceae, is a plant of the family Zosteraceae, a large marine brown algae plant growing in seawater. The kelp has high nutritive value and certain medicinal value. The kelp is rich in mannitol, and is the main component of cordycepic acid contained in the cordyceps sobolifera.

Astragalus root, the Latin name Astragalus membranaceus (Fisch.) Bunge, Astragalus root, Du, Sichuan holly root, baiben, cotton bud, yellow ginseng and sang Shen. . Perennial herbaceous leguminous plants. Has the functions of enhancing the immunity of the organism,Health-care product Liver diseaseDiuresis, anti-aging, anti-stress, blood pressure lowering and wide antibacterial action. Can eliminate albuminuria caused by experimental nephritis, enhance myocardial contraction force, and regulateBlood sugarAnd (4) content. Radix astragali can not only dilate coronary artery, improve myocardial blood supply, and enhance immunity, but also delay cell aging process.

The following formula is formed:

A. 1-3 parts of hawthorn, 2-4 parts of dendrobium, 2-4 parts of silkworm chrysalis powder and kelp and 3-5 parts of astragalus membranaceus.

1-3 parts of hawthorn, 2-4 parts of dendrobium, 3-5 parts of kelp, 2-4 parts of astragalus membranaceus, 2-4 parts of chicory, 2-4 parts of gardenia jasminoides ellis and 1-3 parts of radix puerariae.

1-3 parts of hawthorn, 2-4 parts of dendrobium, 3-5 parts of kelp, 2-4 parts of astragalus, 2-4 parts of chicory, 2-4 parts of gardenia jasminoides ellis, 1-3 parts of kudzu root and 1-3 parts of glabrous greenbrier rhizome.

1-3 parts of hawthorn, 2-4 parts of dendrobium, 3-5 parts of kelp, 2-4 parts of astragalus, 2-4 parts of chicory, 2-4 parts of gardenia jasminoides ellis, 1-3 parts of kudzu root and 1-4 parts of rhodiola rosea.

1-3 parts of hawthorn, 2-4 parts of dendrobium, 3-5 parts of kelp, 2-4 parts of astragalus, 3-7 parts of eggplant stalk, 3-5 parts of celery root, 2-4 parts of bitter almond and 1-3 parts of honeysuckle.

Clinical experiments show that the curative effect statistics of the formula are as follows:

as can be seen from the table above, the kelp and astragalus membranaceus have the advantages of relatively similar curative effects to those of cordyceps cicadae, sufficient raw materials and low cost, have various tonifying efficacies on human bodies, and are a dietary therapy material with a great application prospect.