阅读说明：本技术 一种含有安全剂双苯噁唑酸的精噁唑甘草胺除草组合物 (Fine oxazole glycyrrhiza amine weeding composition containing safener isoxadifen ) 是由 王凤云 徐丹 周银平 张璞 于 2020-07-24 设计创作，主要内容包括：本发明涉及除草剂领域,特别涉及一种含有安全剂双苯噁唑酸的精噁唑甘草胺组合物,具体的其含有活性成分精噁唑甘草胺和安全剂双苯噁唑酸、盐或酯；组合物能明显减轻甚至消除除草剂精噁唑甘草胺对水稻的损伤,并对水稻生长有一定的促进作用,同时不影响精噁唑甘草胺对水稻田杂草的防除效果。一种含有安全剂双苯噁唑酸的精噁唑甘草胺组合物。(The invention relates to the field of herbicides, in particular to an refined oxazole glycyrrhiza amine composition containing a safener isoxadifen acid, which specifically contains an active component of refined oxazole glycyrrhiza amine and the safener isoxadifen acid, salt or ester; the composition can obviously reduce or even eliminate the damage of herbicide-refined oxazole glycyrrhiza amine to rice, has a certain promotion effect on the growth of the rice, and does not influence the preventing and removing effect of the refined oxazole glycyrrhiza amine on weeds in a paddy field. A refined oxazole glycyrrhiza amine composition containing a safener isoxadifen.)

1. An refined oxazole glycyrrhiza amine composition containing a safener isoxadifen acid is characterized by comprising A, B components, wherein the component A is refined oxazole glycyrrhiza amine with a molecular formula (I), and the component B is a compound with a molecular formula (II) or a molecular formula (III);

wherein R is H or C_zH_2z+1Z is an integer of 1 to 6; m₁Is alkali metal ion, alkaline earth metal ion, ammonium ion or organic amine ion.

2. The isoxaflutole herbicidal composition containing safener isoxadifen acid of claim 1 in which M is₁Selected from K, Na, NH_4-x(C_yH_2y+1)_x、NH_4-x[CH(CH₃)₂]_xOr NH_4-x(CH₂CH₂OH) x, y is an integer of 1 to 6, and x is an integer of 0 to 4.

3. The isoxaflutole herbicidal composition containing safener isoxadifen acid of claim 1 in which M is₁Selected from K, Na, NH₄。

4. The isoxaflutole herbicidal composition containing safener isoxadifen acid of claim 1 in which R is selected from the group consisting of H, CH₃Or C₂H₅。

5. The isoxaflutole herbicidal composition containing safener isoxadifen acid as claimed in any of claims 1 to 4, wherein the herbicidal composition comprises 1 to 90% by weight of component A.

6. The isoxaflutole herbicidal composition containing safener isoxadifen acid as claimed in claim 5, wherein component A is 8-50% by weight.

7. The isoxaflutole herbicidal composition containing safener isoxadifen acid as claimed in claim 1, wherein the weight ratio of the component a to the component B in the herbicidal composition is 50:1 to 1: 10.

8. The isoxaflutole herbicidal composition containing safener isoxadifen acid as claimed in claim 7, wherein the weight ratio of component A to component B is 30:1 to 1: 1; more preferably, the weight ratio of the component A to the component B is 20: 1-10: 1.

9. The isoxaflutole herbicidal composition containing the safener isoxadifen-acid as claimed in claim 1, wherein the formulation of said herbicidal composition is dispersible oil suspension, emulsifiable concentrate, wettable powder, aqueous solution, soluble liquid, water dispersible granule, microemulsion or microcapsule, preferably dispersible oil suspension, emulsifiable concentrate, wettable powder.

10. The herbicidal composition of fenoxaprop-p-ethyl containing safener, according to claim 1, further comprising one or more of a fungicidal compound, an insecticidal compound, a herbicidal compound other than the a and B components, a chemical fertilizer, a growth regulator, a phytonutrient or a soil conditioner.

Technical Field

The invention relates to the field of herbicides, in particular to an isoxaflutole herbicide composition containing a safener isoxadifen.

Background

The herbicide plays a great role in protecting crops from weeds, promoting the growth of crops, improving the quality of agricultural products and the like, has been rapidly developed into an important means for agricultural weeding, and is rapidly popularized and applied in production. However, the herbicide is a double-edged sword, and the herbicide can cause phytotoxicity to crops due to the characteristics of the herbicide, processing quality problems, non-standard use, poor environmental conditions and the like in the use process. Crop phytotoxicity caused by the herbicide occurs frequently, large-area phytotoxicity occurs occasionally, and grain loss is serious.

Rice is one of the main grain crops in China, but various weeds in the rice seriously affect the yield of the rice all the time. In recent years, direct seeding rice, which is a labor-saving and water-saving planting mode, is rapidly raised, so that the control of weeds is particularly important, wherein gramineous weeds such as resistant barnyard grass and moleplant seed which have great influence on rice and are difficult to control in a rice field are used.

Barnyard grass is a worldwide malignant weed and is one of serious harm weeds in farmlands in China. The distribution and harm of main weeds in Chinese paddy fields reported by a farmland weed investigation group in China is 0.14 hundred million hectares of the area damaged by barnyard grass only on the paddy fields, and is the most serious weed in the paddy fields in China. In recent years, the resistance of the barnyard grass in the paddy field is getting larger and larger. Plum soldiers, Huang-jiao ball and the like summarize the research progress of the barnyard grass resistance in China, and show that the barnyard grass in the paddy field in China has drug resistance to traditional paddy field herbicides of propanil, thiobencarb, butachlor, quinclorac and triazaben herbicides such as prometryn and the like. In 2009, some farmers in main rice production areas in China use bensulfuron-methyl, pyrazosulfuron-ethyl and other herbicides, the dosage per unit area exceeds 30 times of the recommended dosage, and thus good weeding effect can be achieved.

The moleplant seed in the paddy field is a common weed in the paddy rice planting process, the moleplant seed has a leaf tongue without leaf ears, the leaf tongue of the moleplant seed is shorter than that of the paddy rice, along with the continuous expansion of the area of a direct seeding field, the moleplant seed in the paddy field becomes an important weed, and particularly, the drought is serious in many places, the moleplant seed belongs to the weeds in the dry land, and the control is more difficult in the severe drought. The moleplant seed control agent is less, and if weeds have drug resistance to limited agents, the moleplant seed control is further improved.

At present, herbicides for paddy fields are relatively lagged in development, are not many in varieties and are widely applied to penoxsulam, cyhalofop-butyl, quinclorac and the like, but because the products have longer service life, weeds generate drug resistance, and the effects of preventing and removing barnyard grass and moleplant seed are not ideal. Therefore, a novel herbicide for rice weeding with high efficiency, low toxicity, economy and safety is urgently needed.

The fenoxaprop-p-ethyl glycyrrhiza amine is a phenoxypropanamide herbicide, has an action mechanism of an HPPD inhibitor, and is mainly used for preventing and removing weeds in paddy fields.

The chemical name is as follows: (R) - (2- (4- (6-chlorobenzoxazol-2-oxy) phenoxy) propionyl) glycine ethyl ester; a

The chemical structural formula is as follows:

the fenoxaprop-p-ethyl is a herbicide for rice fields, and particularly has special effects on the aged barnyard grass in the rice fields and the barnyard grass which generates resistance to other herbicides. But it can cause partial damage to rice during use. Therefore, a safener which can effectively solve the safety of the refined oxazole glycyrrhiza amine to the rice is urgently needed to be found.

The isoxadifen is an isoxazole which is researched and developed by an Anthrate company and can reduce or eliminate phytotoxicity of herbicides on crops, and is also called herbicide safener which is also called antidote and is an auxiliary agent for reducing or eliminating phytotoxicity of the herbicides on the crops, and the safener can be used for improving the drug resistance of the crops, solving the problem of preventing and removing weeds which are difficult to remove and expanding the application range and the efficacy of the herbicides

The existing form of the bisbenzoxazole acid is acid, ester or salt, the chemical name of the bisbenzoxazole acid is 4, 5-dihydro-5, 5-diphenyl-1, 2-oxazole-3-carboxylic acid ethyl ester, the name of English is isoxadifen-ethyl,

because the existing herbicides applied in agricultural production have various varieties, high drug toxicity and high residue, weeds can generate resistance easily, and the weeding effect of the herbicide with a single effective component is greatly reduced under the influence of factors such as resistance and the like when the herbicide is used. If a novel herbicide original drug compound is continuously created, the creation period of the new compound is long, the investment is huge, and the creative research on the original drug compound is difficult because the domestic pesticide enterprises are limited by scale and scientific research strength at present. The compounding of the pesticides can solve the problems of high toxicity and poor effect of a single pesticide, the investment is low, the research and development period is short, the current situation of domestic pesticide enterprises is met, the generation of drug resistance of an agent can be delayed by using different pesticides interactively, and the ideal use effect is achieved, so that the compounding of the pesticides with different action mechanisms is a research hotspot in the field of the pesticides at present.

Chinese patent CN1133038A firstly introduces isoxadifen and its ester as safener to prevent and kill weeds in corn field by compounding with nicosulfuron, and obviously improves the safety of corn on the premise of not influencing the pesticide effect. Chinese patent CN101076255A describes the use of a combination of isoxadifen and herbicides rimsulfuron, nicosulfuron, foramsulfuron, diflufenzopyr, mesotrione or dicamba for weeding in corn fields. In the US patent 8530383B2 and the Chinese patent CN102325454A, compounds such as ethyl bisbenzoxazolate are selected as safeners to reduce the damage of 6- (trisubstituted phenyl) -4-amino-pyridine-2-carboxylic acid herbicides on wheat and barley. Chinese patent CN102316728A selects a compound composition such as isoxadifen-ethyl to reduce herbicide damage caused by 6- (trisubstituted phenyl) -4-amino-pyridine-2-carboxylic acid compounds in direct seeding rice and transplanted rice.

The refined oxazole glycyrrhiza amine is a novel phenoxypropanamide herbicide, has a unique action mode, has no cross resistance with other herbicides in the domestic market at present, and aims to delay the resistance of weeds to the refined oxazole glycyrrhiza amine and prolong the market period of the refined oxazole glycyrrhiza amine. Research personnel of our company try to compound the refined oxazole glycyrrhizamine and the isoxadifen acid to observe whether the refined oxazole glycyrrhizamine and the isoxadifen acid have synergistic effect, and a large amount of indoor tests and field tests prove that after the refined oxazole glycyrrhizamine and the isoxadifen acid or the salt of the isoxadifen acid are used as effective components to be compounded, the safety of rice is obviously improved, and the control effect is also improved to a certain extent. In addition, the dosage is lower, the agricultural cost is reduced, the toxicity is lower, the residual quantity is less, and the environment protection is facilitated. Experiments prove that the two have strong synergistic effect, and no relevant report is found at home and abroad at present on the research on whether the refined oxazole glycyrrhiza amine and the isoxadifen acid are compounded as effective components.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: provides a weeding composition containing fenoxaprop-p-ethyl and isoxadifen-ethyl.

The technical scheme for solving the technical problems is as follows:

a weeding composition containing refined oxazole glycyrrhizamine and isoxadifen acid comprises A, B effective components, wherein the component A is refined oxazole glycyrrhizamine of a molecular formula (I), and the component B is a compound of a molecular formula (II) or a molecular formula (III);

wherein R is H or C_zH_2z+1Z is an integer of 1 to 6; m₁Is alkali metal ion, alkaline earth metal ion, ammonium ion or organic amine ion.

Preferably, said M₁Selected from K, Na, NH_4-x(C_yH_2y+1)_x、NH_4-x[CH(CH₃)₂]_xOr NH_4-x(CH₂CH₂OH) x, y is an integer of 1 to 6, and x is an integer of 0 to 4.

Further, said M₁Selected from K, Na, NH₄；

Further, R is H, CH₃Or C₂H₅；

Preferably, the component A in the weeding composition accounts for 1-90% by weight; the preferable weight of the components is 8-50%.

Preferably, the weight ratio of the component A to the component B in the weeding composition is 50: 1-1: 10; preferably, the weight ratio of the component A to the component B is 30: 1-1: 1; more preferably, the weight ratio of the component A to the component B is 20: 1-10: 1.

Preferably, the dosage form of the weeding composition is dispersible oil suspending agent, missible oil and wettable powder.

Preferably, the herbicidal composition further comprises one or more of a fungicidal compound, an insecticidal compound, a further herbicidal compound other than the a and B components, a chemical fertilizer, a growth regulator, a plant nutrient or a soil conditioner.

The Chinese naming of the compound of the invention conflicts with the structural formula, and the structural formula is taken as the standard; except for obvious errors in the formula.

The herbicidal composition contains, in addition to the active ingredients, at least two carriers, and at least one of the carriers is a surfactant. Other carriers besides surfactants may be solid or liquid, and carriers commonly used in formulating herbicide compositions may be used in the present invention, such as one or more of white carbon black, kaolin, diatomaceous earth, bentonite, precipitated calcium carbonate, gypsum, attapulgite, soluble starch, a mixture of urea and an amine fertilizer, glucose, maltose, sucrose, citric acid, anhydrous potassium carbonate, anhydrous sodium carbonate, anhydrous potassium bicarbonate, anhydrous sodium bicarbonate, and the like, or other carriers commonly used in the art.

The surfactant comprises one or more of an emulsifier, a dispersing agent or a wetting agent, wherein the emulsifier is selected from the group consisting of a polyoxyethylene polyoxypropylene ether of p-ethylphenol, a polyoxyethylene-polyoxypropylene block polyether of a styrene phenol formaldehyde resin, a polyoxyethylene fatty acid, a polyoxyethylene fatty alcohol ether, a polyoxyethylene glyceryl trilaurate, a polyoxyethylene dibenzyl biphenyl ether, a polyoxyethylene monolaurate, a polyoxyethylene styrene phenol ether, a polyoxyethylene castor oil, a polyoxyethylene ethoxylated castor oil, a polyoxyethylene alkylphenol ether of polyoxypropylene, a polyoxyethylene styrylphenyl ether, a polyoxyethylene sec-octylphenol, a polyoxyethylene nonylphenol, a polyoxyethylene alkylaryl polyoxyethylene ether, a polyoxyethylene alkylphenol ether, a polyoxyethylene sorbitan fatty acid, a polyoxyethylene fatty alcohol sulfonate, a polyoxyethylene alkyl ether sulfonate, a polyoxyethylene alkyl phenol, Polyoxyethylene alkylphenol formaldehyde condensation compound, dodecyl calcium carbonate, decyl alcohol polyoxyethylene ether sodium sulfosuccinate, sodium alkylphenol polyoxyethylene ether formaldehyde condensation compound sulfate, alkylphenol polyoxyethylene ether succinic acid monoester sulfonate, alkylphenol polyoxyethylene phosphate, alkylphenol polyoxyethylene ether sulfosuccinate, polyoxyethylene fatty acid ester, polymethyl acrylate, polyoxyethylene fatty ammonia, ethoxylated castor oil, alkyl-diethylene glycol ether sodium sulfonate, fatty acid polyglycol ester, quick permeation agent T, polycarboxylate, oleic acid polyglycol 400 ester and fatty alcohol polyvinyl ether.

The wetting agent is selected from the group consisting of sodium alkylnaphthalene sulfonate, sodium dodecyl sulfate, secondary alkyl sodium sulfate, sodium dodecylbenzene sulfonate, fatty alcohol polyglycol ether sulfate, fatty alcohol polyoxyethylene ether, nonylphenol polyoxyethylene ether, sorbitan fatty acid, alkyl naphthalene formaldehyde condensate, alkyl naphthalene sulfonate and a mixture of anionic wetting agents.

The herbicide composition also contains preparation auxiliary agents which are selected from one or more of solvents, thickening agents, antifreezing agents, stabilizing agents, synergists and defoaming agents.

Wherein, the solvent comprises water, N-methyl pyrrolidone, N-dimethylformamide, tributyl phosphate, tetrahydrofurfuryl alcohol, toluene, methyl oleate, xylene, dimethyl sulfoxide, tetrahydrofuran, 1, 4-dioxane, cyclohexanol, cyclohexanone, epoxidized soybean oil, vegetable soybean oil, liquid wax, lubricating oil or solvent oil No. 100, No. 150, No. 180, No. 200 and the like, and can also be other solvents commonly used in the field.

The thickening agent comprises xanthan gum, polyvinyl alcohol, sodium alginate, diatomite, white carbon black, starch, kaolin, organic bentonite and the like, and can also be other thickening agents commonly used in the field.

The synergist includes organic silicon, vegetable oil, and inorganic salts including ammonium nitrate, ammonium sulfate, and ammonium urate. Other synergists commonly used in the art are also possible.

The herbicide composition provided by the invention is in the form of emulsifiable solution, aqueous emulsion, aqueous suspension, oil suspension, wettable powder, water dispersible granules, soluble powder or soluble granules, and the dosage forms can be prepared by a conventional method in the field.

The weeding composition provided by the invention is used for preventing and removing weeds in paddy fields and reducing damage to the paddy fields. The composition can obviously reduce or even eliminate the damage of herbicide glycyrrhiza uralensis amine to rice, and does not influence the preventing and removing effect of glycyrrhiza uralensis amine to weeds in paddy fields.

Detailed Description

The invention is illustrated but not limited by the following examples. The technical solutions protected by the present invention are all the simple replacements or modifications made by the skilled person in the art.