Pharmaceutical formulation for treating rhinitis and preparation method thereof

文档序号:1104319 发布日期:2020-09-29 浏览:18次 中文

阅读说明:本技术 一种治疗鼻炎的药物配方及其制备方法 (Pharmaceutical formulation for treating rhinitis and preparation method thereof ) 是由 卢小浩 于 2020-06-24 设计创作,主要内容包括:本发明公开了一种治疗鼻炎的药物配方及其制备方法,包括鹅不食草、细辛、滑石、薄荷叶、氢氧化钾。有益效果在于:本发明的药方能够治疗慢性鼻炎、过敏性鼻炎、鼻甲肥大及鼻息肉等疾病,配方内含多种治疗鼻炎的有效药物,治疗效果好,且可在短时间内达到很好的疗效,不易复发、制造成本较低,便于广泛推广。(The invention discloses a pharmaceutical formulation for treating rhinitis and a preparation method thereof. Has the advantages that: the prescription of the invention can treat diseases such as chronic rhinitis, allergic rhinitis, hypertrophy of nasal turbinates and nasal polyp, contains various effective medicines for treating rhinitis, has good treatment effect, can achieve good treatment effect in a short time, is not easy to relapse, has lower manufacturing cost and is convenient for wide popularization.)

1. A pharmaceutical formulation for treating rhinitis is characterized in that: comprises herba Centipedae, herba asari, pulvis Talci, folium Menthae, and potassium hydroxide.

2. The pharmaceutical formulation for the treatment of rhinitis according to claim 1, wherein: the formulation also includes glycerin.

3. A pharmaceutical formulation according to claim 1 or 2, wherein: the composite material consists of the following raw materials in percentage by weight: 8-18% of centipeda minima, 3-11% of asarum, 45-55% of talcum, 4-12% of mint leaf, 2-10% of potassium hydroxide and 8-20% of glycerol.

4. The pharmaceutical formulation for the treatment of rhinitis according to claim 3, wherein: the composite material consists of the following raw materials in percentage by weight: 14% of centipeda minima, 6% of asarum, 50% of talcum, 8% of mint leaf, 6% of potassium hydroxide and 16% of glycerol.

5. A process for the preparation of a pharmaceutical formulation for the treatment of rhinitis according to any one of claims 4, characterized in that: the method comprises the following steps:

s1, weighing the medicines according to the weight ratio;

s2, shaking off silt from the centipeda minima, removing impurities, cutting into short sections, screening out dust, drying and grinding into powder for later use;

s3, removing impurities from herba asari, cleaning with water, slightly moistening, cutting into segments, air drying, and grinding into powder;

s4, washing mint leaves with water, cutting into segments, airing and grinding into powder for later use;

s5, grinding the talc and the potassium hydroxide into powder according to a known process for later use;

s6, pouring the powder prepared in the steps S2-S5 into glycerol, uniformly mixing, sealing and storing to a shade place, and taking out for use.

6. The pharmaceutical formulation for treating rhinitis according to claim 5, wherein: in step S5, the potassium hydroxide is needed to be performed in an oxygen-free and water-free environment during the grinding process.

7. The pharmaceutical formulation for treating rhinitis according to claim 5, wherein: in step S6, when the ointment is used, the ointment should be sealed immediately after being taken out.

Technical Field

The invention relates to the technical field of external medicines, in particular to a medicine formula for treating rhinitis and a preparation method thereof.

Background

Rhinitis is a common disease, namely nasal inflammatory disease, and is inflammation of nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors and certain systemic diseases. The main pathological changes of rhinitis are congestion, swelling, exudation, hyperplasia, atrophy or necrosis of the nasal mucosa. Especially in the present days that the environmental pollution is more and more serious and the extreme weather is more and more infrequent, the rhinitis patients are more and tend to be in a low age. Rhinitis seems to be a little disease with great harm, and causes great influence on five sense organs of a human body in the disease period, thereby bringing great pain to the work and life of rhinitis patients. Failure to obtain effective treatment for a long period of time can also induce a variety of serious diseases and even be life threatening. The nasopharynx swelling of Jiucheng is caused by the aggravation of rhinitis. Other complications resulting from rhinitis are: emphysema, pulmonary heart disease, asthma, otitis media, meningitis, etc. According to statistics: the patient suffers from sleep apnea syndrome due to long-time stuffy nose, difficult breathing, insufficient oxygen during sleep, cerebral infarction, hypertension, sudden heart disease and the like under severe conditions, and even sudden death at night, which occurs in all hospitals. Allergic rhinitis sensitive to environmental factors often causes patients to sneeze and tear continuously due to dust and cold air, and the normal work, rest and life of the patients are seriously influenced.

At present, many medicines for treating diseases such as chronic rhinitis, allergic rhinitis, nasal polyp, hypertrophy of nasal turbinates and the like have the defects of insufficient obvious effect, low cure rate, long treatment time, high treatment cost, repeated relapse and the like.

Disclosure of Invention

The invention aims to solve the problems and provide a pharmaceutical formulation for treating rhinitis.

The invention realizes the purpose through the following technical scheme:

a pharmaceutical formulation for treating rhinitis comprises herba Centipedae, herba asari, pulvis Talci, folium Menthae, and potassium hydroxide.

Further, the formulation may also include glycerin.

Further, the feed is composed of the following raw materials in percentage by weight: 8-18% of centipeda minima, 3-11% of asarum, 45-55% of talcum, 4-12% of mint leaf, 2-10% of potassium hydroxide and 8-20% of glycerol.

Further, the feed is composed of the following raw materials in percentage by weight: 14% of centipeda minima, 6% of asarum, 50% of talcum, 8% of mint leaf, 6% of potassium hydroxide and 16% of glycerol.

The invention also provides a preparation method for preparing the pharmaceutical formulation for treating rhinitis, which comprises the following steps:

s1, weighing the medicines according to the weight ratio;

s2, shaking off silt from the centipeda minima, removing impurities, cutting into short sections, screening out dust, drying and grinding into powder for later use;

s3, removing impurities from herba asari, cleaning with water, slightly moistening, cutting into segments, air drying, and grinding into powder;

s4, washing mint leaves with water, cutting into segments, airing and grinding into powder for later use;

s5, grinding the talc and the potassium hydroxide into powder according to a known process for later use;

s6, pouring the powder prepared in the steps S2-S5 into glycerol, uniformly mixing, sealing and storing to a shade place, and taking out for use.

Further, in the step S5, the potassium hydroxide is performed in an oxygen-free and water-free environment during the grinding process.

Further, in step S6, when the ointment is used, the ointment needs to be sealed immediately after being taken out.

The medicinal material efficacy analysis of the invention is as follows:

centipeda minima: dispersing wind-cold, relieving stuffy nose, relieving cough, and removing toxic substance. It can be used for treating wind-cold type common cold, nasal obstruction, cough with asthma due to cold-phlegm, sore, carbuncle, and toxic swelling.

Asarum: nature and taste: pungent, warm and slightly toxic; entering heart, lung and kidney meridians; the efficacy is as follows: relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging orifice, warming lung, and eliminating phlegm; the main treatment is as follows: wind-cold type common cold, headache, toothache, rheumatism, nasosinusitis, cough due to lung cold.

Mint leaf: pungent taste and cool nature; entering lung and liver meridians, they have the following actions: has the functions of dispelling wind heat, clearing head and eyes, relieving sore throat and promoting eruption; it can be used for treating wind-heat type common cold, headache, conjunctival congestion, swelling and pain of throat, skin pruritus, measles, aphtha of mouth and tongue, toothache, and urticaria.

The invention has the beneficial effects that: the prescription of the invention can treat diseases such as chronic rhinitis, allergic rhinitis, hypertrophy of nasal turbinates and nasal polyp, contains various effective medicines for treating rhinitis, has good treatment effect, can achieve good treatment effect in a short time, is not easy to relapse, has lower manufacturing cost and is convenient for wide popularization.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

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