阅读说明：本技术 一种婴幼儿湿疹、皮肤瘙痒草本抑菌剂及其制备方法 (Herbal bacteriostatic agent for infantile eczema and skin itch and preparation method thereof ) 是由 杨晓生 于 2020-04-27 设计创作，主要内容包括：本发明公开了一种婴幼儿湿疹、皮肤瘙痒草本抑菌剂及其制备方法,其主要成分与质量含量为：金银花提取物20％、紫草提取物10％、苦参提取物2％、蛇床子提取物12％、薄荷提取物1％、地肤子提取物2％、苯扎氯铵0.5％、乙醇4％、醋酸氯已定1％、冰片0.3％、纯化水45％。本发明开通过在制备中添加乙醇有效的保证了有效的加快了抑菌剂与幼儿皮肤之间的快速契合,避免或减少因身体频繁的扭动导致抑菌剂被顺带擦去的情况,确保抑菌剂在涂抹后可以快速的作用的治疗面,又可以对皮肤表面存在的细菌进行消毒灭杀,避免或减少皮肤出现二次细菌滋生感染的情况,通过添加入金银花成分,不但有效的抑制了湿疹或其他发疹等情况,并且又起到了清热解毒的效果。(The invention discloses a herbaceous bacteriostatic agent for infantile eczema and skin itch and a preparation method thereof, wherein the herbaceous bacteriostatic agent comprises the following main components in percentage by mass: 20% of honeysuckle extract, 10% of lithospermum extract, 2% of sophora flavescens extract, 12% of fructus cnidii extract, 1% of mint extract, 2% of fructus kochiae extract, 0.5% of benzalkonium chloride, 4% of ethanol, 1% of chlorhexidine acetate, 0.3% of borneol and 45% of purified water. The addition of the ethanol in the preparation effectively ensures that the rapid engagement between the bacteriostatic agent and the skin of the infant is effectively accelerated, the condition that the bacteriostatic agent is smoothly wiped off due to frequent wriggling of the body is avoided or reduced, the treatment surface which can rapidly act after the bacteriostatic agent is smeared is ensured, bacteria on the surface of the skin can be disinfected and killed, the condition that the skin is infected by secondary bacteria breeding is avoided or reduced, the situation of eczema or other eruptions and the like is effectively inhibited by adding the honeysuckle components, and the effect of clearing away heat and toxic materials is achieved.)

1. A herbaceous bacteriostatic agent for infant eczema and skin itch and a preparation method thereof, the herbaceous bacteriostatic agent comprises the following main components by mass: 20% of honeysuckle extract, 10% of lithospermum extract, 2% of sophora flavescens extract, 12% of fructus cnidii extract, 1% of mint extract, 2% of fructus kochiae extract, 0.5% of benzalkonium chloride, 4% of ethanol, 1% of chlorhexidine acetate, 0.3% of borneol and 45% of purified water, and is characterized in that: the method comprises the following five steps:

the method comprises the following steps: heating and mixing purified water, benzalkonium chloride and ethanol to obtain a mixed solution for later use;

step two: heating and mixing the honeysuckle extract, the lithospermum extract, the mint extract and the borneol to obtain a mixed solution for the second time;

step three: heating and neutralizing the primary standby mixed solution and the secondary standby mixed solution for three times, uniformly stirring, and standing for 3-5 minutes;

step four: standing the mixed solution prepared in the third step for cooling, then sequentially adding chlorhexidine acetate, the radix sophorae flavescentis extract, the fructus kochiae extract and the fructus cnidii extract, continuously stirring for neutralization to prepare a finished product solution, and standing for 5-7 minutes;

step five: and inspecting and sterilizing the finished product solution, discharging, canning, packaging and warehousing according to the sanitary requirements after the finished product solution is qualified.

2. The herbaceous bacteriostatic agent for infant eczema and skin pruritus and the preparation method thereof according to claim 1, wherein the herbaceous bacteriostatic agent comprises the following components: the mixing temperature of the first standby mixed liquid is 65-70 ℃, the mixing temperature of the second standby mixed liquid is 83-95 ℃, the mixing temperature of the third mixed liquid is 90-93 ℃, and the temperature of the third preparation standing and cooling is 50 ℃.

3. The herbaceous bacteriostatic agent for infant eczema and skin pruritus and the preparation method thereof according to claim 1, wherein the herbaceous bacteriostatic agent comprises the following components: when the mixed liquid is heated and stirred, the mixed liquid needs to be mixed by a stirring kettle, and a heating mechanism, a temperature control mechanism and a stirring mechanism are arranged in the boiler.

4. The herbaceous bacteriostatic agent for infant eczema and skin pruritus and the preparation method thereof according to claim 1, wherein the herbaceous bacteriostatic agent comprises the following components: the honeysuckle, the lithospermum, the radix sophorae flavescentis, the fructus cnidii, the mint and the fructus kochiae are extracted by a membrane separation technology.

5. The herbaceous bacteriostatic agent for infant eczema and skin pruritus and the preparation method thereof according to claim 1, wherein the herbaceous bacteriostatic agent comprises the following components: the prepared finished liquid comprises an excipient, an emulsifier, a stabilizer and a preservative, and the total content of the excipient, the emulsifier, the stabilizer and the preservative is not more than 13%.

Technical Field

The invention relates to the technical field of medical science, in particular to a herbaceous bacteriostatic agent for infant eczema and skin itch and a preparation method thereof.

Background

The skin is used as the first physiological defense line and the largest organ of the human body, constantly participates in the activity of the functions of the body, maintains the unity of opposition of the body and the natural environment, and has nearly perfect physiological protection function: such as barrier function, sensory function, body temperature regulation, absorption, secretion and excretion, etc., which play an important role in maintaining the health of the body, whereas hundreds of microorganisms, including viruses, mites, bacteria, fungi, etc., are parasitic on the surface of the skin, and different micro-ecological environments are formed in various parts. Under normal conditions, most of the microorganisms do not cause diseases, and only under certain conditions, the microorganisms invade the skin, so that the shape, the structure and the function of the skin are changed, a pathological process is generated, and various clinical manifestations, namely skin diseases, are correspondingly generated.

Skin infection caused by fungi or bacteria is one of the more common skin diseases, the clinically common antifungal drugs mostly contain hormone in order to increase the anti-inflammatory effect, and patients with fungal skin diseases feel itching relieving effect after using the hormone-containing dermatologic medicine for one or two days, but the symptoms of disease aggravation can be shown after the application of the hormone-containing dermatologic medicine for one or two days.

The bacteriostatic agent is a substance capable of inhibiting the growth of bacteria, and the bacteriostatic agent can not kill the bacteria, but can inhibit the growth of the bacteria, prevent the bacteria from breeding too much and endangering health; all essential oils have the capability of inhibiting the growth of bacteria more or less, some essential oils only inhibit the growth of certain special germs, and some essential oils inhibit many kinds of germs, but the pertinence of the existing bacteriostatic products is weak to adapt to the use of the general social population, but the products are difficult to be better applied to infants with fragile skin, so that the bacteriostatic effect of the skin of the infants is difficult to achieve the inherent treatment effect, the skin of the infants cannot be nursed while bacteriostasis is carried out, and the traditional bacteriostatic agent cannot achieve the good bacteriostatic effect, so the traditional bacteriostatic agent needs to be further improved to meet the operation requirement.

Disclosure of Invention

The invention aims to provide a herbaceous bacteriostatic agent for infant eczema and skin itch and a preparation method thereof, which aim to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

a herbaceous bacteriostatic agent for infant eczema and skin itch and a preparation method thereof, the herbaceous bacteriostatic agent comprises the following main components by mass: 20% of honeysuckle extract, 10% of lithospermum extract, 2% of sophora flavescens extract, 12% of fructus cnidii extract, 1% of mint extract, 2% of fructus kochiae extract, 0.5% of benzalkonium chloride, 4% of ethanol, 1% of chlorhexidine acetate, 0.3% of borneol and 45% of purified water, and is characterized in that: the method comprises the following five steps:

the method comprises the following steps: heating and mixing purified water, benzalkonium chloride and ethanol to obtain a mixed solution for later use;

step two: heating and mixing the honeysuckle extract, the lithospermum extract, the mint extract and the borneol to obtain a mixed solution for the second time;

step three: heating and neutralizing the primary standby mixed solution and the secondary standby mixed solution for three times, uniformly stirring, and standing for 3-5 minutes;

step four: standing the mixed solution prepared in the third step for cooling, then sequentially adding chlorhexidine acetate, the radix sophorae flavescentis extract, the fructus kochiae extract and the fructus cnidii extract, continuously stirring for neutralization to prepare a finished product solution, and standing for 5-7 minutes;

step five: and inspecting and sterilizing the finished product solution, discharging, canning, packaging and warehousing according to the sanitary requirements after the finished product solution is qualified.

Further, the mixing temperature of the first standby mixed liquid is 65-70 ℃, the mixing temperature of the second standby mixed liquid is 83-95 ℃, the mixing temperature of the third mixed liquid is 90-93 ℃, and the temperature of the third preparation standing and cooling is 50 ℃.

Further, when the mixed liquid is heated and stirred, the mixed liquid needs to be mixed by a stirring kettle, and a heating mechanism, a temperature control mechanism and a stirring mechanism are arranged in the boiler.

Furthermore, the honeysuckle, the lithospermum, the radix sophorae flavescentis, the fructus cnidii, the mint and the fructus kochiae are extracted by a membrane separation technology.

Further, the prepared finished liquid comprises an excipient, an emulsifier, a stabilizer and a preservative, and the total content of the excipient, the emulsifier, the stabilizer and the preservative is not more than 13%.

Compared with the prior art, the invention has the beneficial effects that: the infant eczema and skin itch herbal bacteriostatic agent and the preparation method thereof effectively ensure that the rapid engagement between the bacteriostatic agent and the skin of an infant is effectively accelerated by adding ethanol in the preparation, so that the bacteriostatic agent forms a quick-drying effect after being smeared, the condition that the bacteriostatic agent is wiped off along the belt due to frequent wriggling of the body is avoided or reduced, a treatment surface which can rapidly act after the bacteriostatic agent is smeared is ensured, meanwhile, the inherent characteristics of the effective ethanol can disinfect and kill bacteria existing on the surface of the skin, the condition that the skin is infected by secondary bacteria breeding is avoided or reduced, the conditions of eczema or other eruptions and the like are effectively inhibited by adding honeysuckle flower components, the heat clearing and detoxifying effects are achieved, the discomfort existing in the skin of the infant is reduced while the treatment is carried out, and the treatment requirement of the skin of the infant is effectively met, realizes the bacteriostatic effect aiming at chemistry and protection.

Drawings

FIG. 1 is a schematic flow chart of the preparation method of the present invention;

FIG. 2 is a diagram illustrating the physical and chemical indexes of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front", "rear", "both ends", "one end", "the other end", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, such as "connected," which may be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.