阅读说明：本技术 一种外用治疗皮肤溃疡的虎参叶精油 (External-use tiger ginseng leaf essential oil for treating skin ulcer ) 是由 苗明三 熊维政 左艇 李磊 于 2019-12-18 设计创作，主要内容包括：本发明涉及外用治疗皮肤溃疡的虎参叶精油,可有效解决皮肤溃疡的治疗用药问题,其解决的技术方案是,由以下组分：黄柏精油2.5-3.5mL、没药精油2.5-3.5mL、红花精油4-6mL、丹参精油4-6mL、虎杖精油6-8mL、苦参精油6-8mL、当归精油4-6mL、桂枝精油5-7mL、侧柏叶7-9mL、甘草精油6-8mL和冰片9-11g溶解、混匀制成,本发明原料丰富,制备方法简单,易生产制备,使用方便,效果好,具有改善皮肤溃疡的功能,是治疗皮肤溃疡药物上的创新,有显著的经济和社会效益。(The invention relates to external-use tiger ginseng leaf essential oil for treating skin ulcer, which can effectively solve the problem of medicament application for treating skin ulcer and adopts the technical scheme that the external-use tiger ginseng leaf essential oil comprises the following components: 2.5-3.5mL of phellodendron essential oil, 2.5-3.5mL of myrrh essential oil, 4-6mL of safflower essential oil, 4-6mL of salvia essential oil, 6-8mL of polygonum cuspidatum essential oil, 6-8mL of sophora flavescens essential oil, 4-6mL of angelica essential oil, 5-7mL of cassia twig essential oil, 7-9mL of cacumen biotae, 6-8mL of liquorice essential oil and 9-11g of borneol are dissolved and uniformly mixed to prepare the traditional Chinese medicine.)

1. The external-use tiger ginseng leaf essential oil for treating skin ulcer is characterized by comprising the following components: 2.5-3.5mL of phellodendron essential oil, 2.5-3.5mL of myrrh essential oil, 4-6mL of safflower essential oil, 4-6mL of salvia essential oil, 6-8mL of giant knotweed essential oil, 6-8mL of sophora flavescens essential oil, 4-6mL of angelica essential oil, 5-7mL of cassia twig essential oil, 7-9mL of cacumen biotae, 6-8mL of liquorice essential oil and 9-11g of borneol are dissolved and uniformly mixed to prepare the traditional Chinese medicine, wherein:

the cortex phellodendri essential oil is prepared by crushing cortex phellodendri into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂Extracting fluid, wherein the weight volume ratio of liquid to material is 1: 10-20, the weight volume ratio refers to that the solid is counted by g, the liquid is counted by mL, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, and the separation pressure isThe force is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that the phellodendron essential oil is obtained;

the preparation methods of the myrrh essential oil, the safflower essential oil, the salvia essential oil, the giant knotweed essential oil, the sophora flavescens essential oil, the angelica essential oil, the cassia twig essential oil, the cacumen biotae and the liquorice essential oil are the same as the golden cypress essential oil.

2. The essential oil of tiger ginseng leaf for external use for treating skin ulcer as claimed in claim 1, which is prepared from the following components: 3mL of phellodendron essential oil, 3mL of myrrh essential oil, 5mL of safflower essential oil, 5mL of salvia essential oil, 7mL of giant knotweed essential oil, 7mL of sophora flavescens essential oil, 5mL of angelica essential oil, 6mL of cassia twig essential oil, 8mL of cacumen biotae, 7mL of liquorice essential oil and 10g of borneol are dissolved and mixed uniformly to prepare the traditional Chinese medicine.

3. The essential oil of tiger ginseng leaf for external use for treating skin ulcer as claimed in claim 1, which is prepared from the following components: 2.8mL of phellodendron essential oil, 3.3mL of myrrh essential oil, 4.5mL of safflower essential oil, 5.5mL of salvia essential oil, 6.5mL of giant knotweed essential oil, 7.5mL of sophora flavescens essential oil, 4.5mL of angelica essential oil, 6.5mL of cassia twig essential oil, 7.5mL of cacumen biotae, 7.5mL of liquorice essential oil and 9.5g of borneol are dissolved and mixed uniformly to prepare the traditional Chinese medicine.

4. The essential oil of tiger ginseng leaf for external use for treating skin ulcer as claimed in claim 1, which is prepared from the following components: 3.3mL of phellodendron essential oil, 2.8mL of myrrh essential oil, 5.5mL of safflower essential oil, 4.5mL of salvia essential oil, 7.5mL of giant knotweed essential oil, 6.5mL of sophora flavescens essential oil, 5.5mL of angelica essential oil, 5.5mL of cassia twig essential oil, 8.5mL of cacumen biotae, 6.5mL of liquorice essential oil and 10.5g of borneol are dissolved and mixed uniformly to prepare the traditional Chinese medicine.

Technical Field

The invention relates to a medicine, in particular to an external-use tiger ginseng leaf essential oil for treating skin ulcer.

Background

Skin ulcer is a common and frequently-occurring disease in surgery of traditional Chinese medicine, is a body surface disease which is characterized in that skin ulcer is taken as a main clinical manifestation and can not be healed for a long time and skin tissue defect is liquefied, infected and necrotic, and is generally a long-term unhealed patient after ulcer of skin ulcer in surgery of traditional Chinese medicine. Because the sore surface is difficult to heal and the consumption is very large, great psychological pressure and economic loss are caused to the patient, and the physical health and the life quality of the patient are seriously influenced.

Skin ulcer is limited skin tissue defect caused by traumatic microorganism infection, tumor circulation disorder and nerve dysfunction, immune dysfunction or congenital skin defect, traumatic ulcer is usually caused by physical and chemical factors directly acting on tissues, microbial infectious diseases are mostly caused by tissue destruction, nodule or tumor ulceration caused by bacteria, fungal spirochetes, viruses and the like, vascular inflammatory ulcer system caused by immune dysfunction is formed by necrosis of tissues caused by artery or arteriolar inflammation, circulation or nerve dysfunction belongs to the genus of nutrition disorder is caused by tissue necrosis, such as varicose leprosy ulcer and the like.

At present, although there are many drugs for treating skin ulcer, such as antiallergic drugs, antiparasitic drugs, antibiotics, and drugs for promoting ulcer healing, their use and efficacy are not satisfactory for various reasons, so how to effectively treat skin ulcer is a technical problem of interest in the industry.

Disclosure of Invention

Aiming at the situation, in order to overcome the defects of the prior art, the invention aims to provide the tiger ginseng leaf essential oil for treating skin ulcer by external application, which can effectively solve the problem of medicament for treating skin ulcer.

The technical scheme for solving the problem is that the external-use tiger ginseng leaf essential oil for treating skin ulcer comprises the following components: 2.5-3.5mL of phellodendron essential oil, 2.5-3.5mL of myrrh essential oil, 4-6mL of safflower essential oil, 4-6mL of salvia essential oil, 6-8mL of giant knotweed essential oil, 6-8mL of sophora flavescens essential oil, 4-6mL of angelica essential oil, 5-7mL of cassia twig essential oil, 7-9mL of cacumen biotae, 6-8mL of liquorice essential oil and 9-11g of borneol are dissolved and uniformly mixed to prepare the traditional Chinese medicine, wherein:

the cortex phellodendri essential oil is prepared by crushing cortex phellodendri into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂Extracting a fluid, wherein the weight-volume ratio of liquid to material is 1: 10-20, the weight-volume ratio refers to that the solid is measured in g, the liquid is measured in mL (the same below), the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that the phellodendron essential oil is obtained;

the myrrh essential oil is prepared by crushing myrrh, sieving with a sieve of 10-20 meshes and performing supercritical CO₂Fluid extraction is carried out, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that myrrh essential oil is obtained;

the safflower essential oil is prepared by crushing safflower into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂Fluid extraction is carried out, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain safflower essential oil;

the salvia essential oil is prepared by crushing salvia into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂Extracting with a fluid, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain the salvia essential oil;

the giant knotweed essential oil is prepared by crushing giant knotweed into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂Fluid extraction is carried out, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain giant knotweed essential oil;

the sophora flavescens essential oil is prepared by crushing sophora flavescens into 10-20 mesh coarse powder and performing supercritical CO₂Fluid extraction is carried out, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain the sophora flavescens essential oil;

the angelica essential oil is prepared by crushing angelica, sieving with a sieve of 10-20 meshes and carrying out supercritical CO extraction₂Extracting with a liquid material in a weight-volume ratio of 1: 10-20Taking the angelica essential oil, wherein the temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that the angelica essential oil is obtained;

the cassia twig essential oil is prepared by crushing cassia twigs into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂Extracting with a fluid, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain the cassia twig essential oil;

the cacumen biotae essential oil is prepared by crushing cacumen biotae into coarse powder which is sieved by a sieve of 10-20 meshes and performing supercritical CO treatment₂Extracting with a fluid, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain the cacumen biotae essential oil;

the licorice essential oil is prepared by crushing licorice into coarse powder which is sieved by a sieve of 10-20 meshes and supercritical CO₂And (3) fluid extraction, wherein the weight-volume ratio of liquid to material is 1: 10-20, the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that the licorice essential oil is obtained.

The invention has the advantages of rich raw materials, simple preparation method, easy production and preparation, convenient use and good effect, has the function of improving skin ulcer, is an innovation on the medicine for treating skin ulcer, and has remarkable economic and social benefits.

Detailed Description

The following examples are provided to explain the present invention in detail.

The invention may be embodied in the form of the following examples.