阅读说明：本技术 大脑缺血的RNAi治疗 (RNAi treatment of cerebral ischemia ) 是由 J.温 于 2017-12-29 设计创作，主要内容包括：本发明提供治疗大脑缺血的新方法,其包括给予聚合物纳米胶囊或其组合物。所述纳米胶囊包括聚合物壳和RNAi(例如miRNA)分子,其中聚合物壳包括a)至少一种带正电荷的单体,b)至少一种可降解的交联剂,和c)至少一种中性单体；且所述RNAi分子为患有大脑缺血的受试者提供治疗益处。本发明还公开了所述聚合物纳米胶囊的组合物。(The present invention provides a novel method of treating cerebral ischemia comprising administering a polymeric nanocapsule or a composition thereof. The nanocapsule comprises a polymeric shell and an RNAi (e.g., miRNA) molecule, wherein the polymeric shell comprises a) at least one positively charged monomer, b) at least one degradable crosslinking agent, and c) at least one neutral monomer; and the RNAi molecules provide a therapeutic benefit to a subject suffering from cerebral ischemia. The invention also discloses a composition of the polymer nanocapsule.)