阅读说明：本技术 免疫调节蛋白 (Immunomodulatory proteins ) 是由 理查德·约翰·普利斯 于 2012-10-17 设计创作，主要内容包括：本申请涉及免疫调节蛋白。公开了一种用于治疗哺乳动物受试者的自身免疫性疾病或炎性疾病的方法,所述方法包括：向哺乳动物受试者施用有效量的多聚蛋白,所述多聚蛋白包含5个、6个或7个多肽单体单元；其中每个多肽单体单元包含Fc受体结合部分,所述Fc受体结合部分包含2个免疫球蛋白G重链恒定区；其中每个免疫球蛋白G重链恒定区包含半胱氨酸残基,所述半胱氨酸残基通过二硫键连接到毗邻多肽单体单元的免疫球蛋白G重链恒定区的半胱氨酸残基；其中所述多聚蛋白不包含另外的免疫调节部分,或当施用到哺乳动物受试者时引起抗原特异性免疫抑制的抗原部分。(The present application relates to immunomodulatory proteins. Disclosed is a method for treating an autoimmune disease or an inflammatory disease in a mammalian subject, the method comprising: administering to a mammalian subject an effective amount of a polymeric protein comprising 5, 6, or 7 polypeptide monomer units; wherein each polypeptide monomer unit comprises an Fc receptor binding portion comprising 2 immunoglobulin G heavy chain constant regions; wherein each immunoglobulin G heavy chain constant region comprises a cysteine residue that is disulfide bonded to a cysteine residue of an immunoglobulin G heavy chain constant region of an adjacent polypeptide monomeric unit; wherein the polymeric protein does not comprise an additional immunomodulatory portion, or an antigenic portion that causes antigen-specific immunosuppression when administered to a mammalian subject.)