阅读说明：本技术 用于产生感兴趣的分子的经遗传优化的微生物 (Genetically optimized microorganisms for producing molecules of interest ) 是由 C·波伊萨特 N·莫林 于 2018-01-26 设计创作，主要内容包括：本发明涉及一种表达功能性I型或II型RuBisCO酶和功能性磷酸核酮糖激酶(PRK)的经遗传修饰的微生物,且在该微生物中糖酵解途径至少部分地受抑制,所述微生物经遗传修饰以产生外源性分子和/或过产生内源性分子。根据本发明,戊糖磷酸途径的氧化分支也可至少部分地受抑制。本发明还涉及此类经遗传修饰的微生物用于产生或过产生感兴趣的分子的用途,且涉及用于合成或生物转化感兴趣的分子的方法。(The present invention relates to a genetically modified microorganism expressing a functional RuBisCO enzyme type I or II and a functional Phosphoribulokinase (PRK) and in which the glycolytic pathway is at least partially inhibited, said microorganism being genetically modified to produce an exogenous molecule and/or to overproduce an endogenous molecule. According to the invention, the oxidative branch of the pentose phosphate pathway may also be at least partially inhibited. The invention also relates to the use of such genetically modified microorganisms for producing or overproducing a molecule of interest and to a method for synthesizing or biotransforming a molecule of interest.)