阅读说明：本技术 一种抗病毒中草药饲料添加剂 (Antiviral Chinese herbal medicine feed additive ) 是由 丁常宏 吴昊 于 2019-11-03 设计创作，主要内容包括：本发明涉及一种饲料添加剂,具体为一种抗病毒中草药饲料添加剂,包括以下重量份的原料组成：松针粉30-45份、芒硝粉6-10份、党参叶提取物7-10份、麦饭石粉6-12份、橘皮粉5-10份、剌五加提取物5-10份、地丁草粉8-14份、板蓝根15-25份、石膏粉6-12份、绵马贯众4-8份、薄荷脑3-5份、蟾皮3-5份、微量元素8-18份、维生素10-25份。本发明通过将多种中草药与微量元素和维生素复配,一来可以均衡受体营养,二来多种微量元素可以调节机体新陈代谢,促进生长发育,增强抗病能力和提高饲料利用率,通过多种中草药复配,可以显著提高本发明的抗病毒性能。(The invention relates to a feed additive, in particular to an antiviral Chinese herbal medicine feed additive, which comprises the following raw materials in parts by weight: 30-45 parts of pine needle powder, 6-10 parts of mirabilite powder, 7-10 parts of codonopsis pilosula leaf extract, 6-12 parts of medical stone powder, 5-10 parts of orange peel powder, 5-10 parts of acanthopanax extract, 8-14 parts of bunge corydalis herb powder, 15-25 parts of isatis root, 6-12 parts of gypsum powder, 4-8 parts of male fern rhizome, 3-5 parts of menthol, 3-5 parts of toad skin, 8-18 parts of trace elements and 10-25 parts of vitamin. The invention can balance the nutrition of the receptor by compounding various Chinese herbal medicines with trace elements and vitamins, can regulate the metabolism of the organism by various trace elements, promotes the growth and development, enhances the disease resistance and improves the utilization rate of the feed, and can obviously improve the antiviral performance by compounding various Chinese herbal medicines.)

1. An antiviral Chinese herbal medicine feed additive is characterized by comprising the following raw materials in parts by weight: 30-45 parts of pine needle powder, 6-10 parts of mirabilite powder, 7-10 parts of codonopsis pilosula leaf extract, 6-12 parts of medical stone powder, 5-10 parts of orange peel powder, 5-10 parts of acanthopanax extract, 8-14 parts of bunge corydalis herb powder, 15-25 parts of isatis root, 6-12 parts of gypsum powder, 4-8 parts of male fern rhizome, 3-5 parts of menthol, 3-5 parts of toad skin, 8-18 parts of trace elements and 10-25 parts of vitamin.

2. The antiviral Chinese herbal medicine feed additive as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 35 parts of pine needle powder, 7 parts of mirabilite powder, 8 parts of codonopsis pilosula leaf extract, 8 parts of medical stone powder, 7 parts of orange peel powder, 6 parts of acanthopanax senticosus extract, 10 parts of bunge corydalis herb powder, 18 parts of isatis root, 8 parts of gypsum powder, 5 parts of male fern rhizome, 4 parts of menthol, 4 parts of toad skin, 10 parts of trace elements and 15 parts of vitamin.

3. The antiviral Chinese herbal medicine feed additive as claimed in claim 1, wherein the trace elements are any mixture of copper, iron, zinc, cobalt, manganese, iodine, selenium, calcium and phosphorus.

4. The antiviral Chinese herbal medicine feed additive as claimed in claim 1, wherein said vitamin is any mixture of vitamin A, vitamin D2, vitamin E, vitamin K3, vitamin B1, vitamin D3, vitamin B2, vitamin B6, vitamin C.

5. The antiviral Chinese herbal medicine feed additive as claimed in claim 1, wherein the Codonopsis pilosula leaf extract is prepared by the following steps: cleaning and crushing codonopsis pilosula leaves, adding 20-30 times of deionized water, heating to 80-90 ℃, keeping the temperature for 20-30min, filtering residues, adding 5-10 times of deionized water again, heating to 90-100 ℃, keeping the temperature for 30-40min, filtering residues, combining extracting solutions of the two times, concentrating the extracting solutions to 1/30-/1/50 of the original volume, and crushing the extracting solutions by using a wall-breaking superfine powder technology after spray drying and pulverizing.

6. The antiviral Chinese herbal medicine feed additive as claimed in claim 5, wherein the Codonopsis pilosula leaf extract is prepared by the following steps: cleaning and crushing codonopsis pilosula leaves, adding 25 times of deionized water, heating to 85 ℃, keeping the temperature for 25min, filtering residues, adding 8 times of deionized water again, heating to 100 ℃, keeping the temperature for 35min, filtering the residues, combining the two extracting solutions, concentrating the extracting solution to 1/40 of the original volume, spray-drying to prepare powder, and crushing the powder by using a wall-broken ultrafine powder technology.

7. The antiviral Chinese herbal medicine feed additive as claimed in claim 1, wherein the acanthopanax senticosus extract is prepared by the following steps: cleaning and crushing acanthopanax senticosus, adding 15-25 times of deionized water, sending into an ultrasonic extraction tank for primary extraction, wherein the ultrasonic power is 300-450W, the frequency is 35-45kHz, the extraction time is 0.5-2h, the extraction temperature is 60-80 ℃, extracting an extracting solution after the primary extraction is finished, adding 10-15 times of deionized water again for secondary extraction, keeping the extraction parameters and time unchanged, combining the extracting solutions after the extraction is finished, concentrating the extracting solution to 1/30-/1/50 of the original volume, and crushing the extracting solution by using a wall-breaking ultrafine powder technology after spray drying and powder preparation.

8. The antiviral Chinese herbal medicine feed additive as claimed in claim 7, wherein the Acanthopanax senticosus extract is prepared by the following steps: cleaning and crushing acanthopanax senticosus, adding 20 times of deionized water, feeding into an ultrasonic extraction tank for primary extraction, wherein the ultrasonic power is 350W, the frequency is 40kHz, the extraction time is 1h, the extraction temperature is 85 ℃, extracting an extracting solution after the primary extraction is finished, adding 10 times of deionized water again for secondary extraction, keeping the extraction parameters and time unchanged, combining the extracting solutions after the secondary extraction is finished, concentrating the extracting solution to 1/40 with the original volume, and crushing the extracting solution by a wall-broken ultrafine powder technology after spray drying and pulverizing.

9. The antiviral Chinese herbal medicine feed additive as claimed in claim 1, wherein the raw material composition further comprises any one of scutellaria baicalensis, phellodendron amurense, ephedra, and fried bitter apricot seeds.

10. The antiviral Chinese herbal medicine feed additive as claimed in claim 9, wherein the scutellaria baicalensis, the phellodendron amurense, the roasted ephedra herb and the fried bitter apricot seed are added in the invention in parts by weight: 6-8 parts of scutellaria baicalensis, 6-8 parts of golden cypress, 5-7 parts of roasted ephedra or 4-7 parts of fried bitter almond.

Technical Field

The invention relates to a feed additive, in particular to an antiviral Chinese herbal medicine feed additive.

Background

The feed additive is a small amount or trace substance added in the production, processing and using processes of feed, and the feed additive is small in dosage but remarkable in effect. The feed additive is a raw material inevitably used in modern feed industry, and has obvious effects on strengthening the nutritive value of basic feed, improving the production performance of animals, ensuring the health of the animals, saving the feed cost, improving the quality of animal products and the like.

The prior feed additive has the following problems in production and use:

abuse of antibiotics and hormones in feed additives in early stages of feed additive production, low doses of antibiotics or sulfonamides were used to prevent disease or diarrhea in livestock and poultry. The low dose of antibiotics can destroy the ecological balance among microorganisms (including pathogenic microorganisms) in the natural environment, and the antibiotics have residues in food, thereby seriously affecting the treatment of human diseases and the inheritance of human beings.

The dosage of some trace elements is too much or not enough, the common trace elements in the feed additive comprise iron, copper, manganese, zinc, iodine, selenium and the like, and the trace elements exist in the state of ions, molecules or compounds with complex structures after entering the human body, and the biochemical effects under different states are different. Too little can produce deficiency symptoms, and too much can cause poisoning or create imbalance. Therefore, the content must be proper and the mixture must be uniform, otherwise the opposite effect can be achieved.

How to enhance the immune function of animal organisms and improve the anti-stress and anti-disease capability of animals, and the method has the advantages of no residue, difficult generation of drug resistance and the like, and is a hotspot of animal nutrition research in recent years.

Disclosure of Invention

In view of the above, the invention provides an antiviral Chinese herbal medicine feed additive, which can balance the nutrition of a receptor by compounding various Chinese herbal medicines with trace elements and vitamins, can regulate the metabolism of an organism by compounding various trace elements, promotes the growth and development, enhances the disease resistance and improves the feed utilization rate, and can obviously improve the antiviral performance of the antiviral Chinese herbal medicine feed additive by compounding various Chinese herbal medicines.

In order to achieve the purpose, the invention adopts the following technical scheme:

an antiviral Chinese herbal medicine feed additive comprises the following raw materials in parts by weight: 30-45 parts of pine needle powder, 6-10 parts of mirabilite powder, 7-10 parts of codonopsis pilosula leaf extract, 6-12 parts of medical stone powder, 5-10 parts of orange peel powder, 5-10 parts of acanthopanax extract, 8-14 parts of bunge corydalis herb powder, 15-25 parts of isatis root, 6-12 parts of gypsum powder, 4-8 parts of male fern rhizome, 3-5 parts of menthol, 3-5 parts of toad skin, 8-18 parts of trace elements and 10-25 parts of vitamin.

Preferably, the antiviral Chinese herbal medicine feed additive comprises the following raw materials in parts by weight: 35 parts of pine needle powder, 7 parts of mirabilite powder, 8 parts of codonopsis pilosula leaf extract, 8 parts of medical stone powder, 7 parts of orange peel powder, 6 parts of acanthopanax senticosus extract, 10 parts of bunge corydalis herb powder, 18 parts of isatis root, 8 parts of gypsum powder, 5 parts of male fern rhizome, 4 parts of menthol, 4 parts of toad skin, 10 parts of trace elements and 15 parts of vitamin.

Preferably, the trace elements are any mixture of copper, iron, zinc, cobalt, manganese, iodine, selenium, calcium and phosphorus.

Preferably, the vitamin is any mixture of vitamin A, vitamin D2, vitamin E, vitamin K3, vitamin B1, vitamin D3, vitamin B2, vitamin B6 and vitamin C.

Preferably, the preparation method of the codonopsis pilosula leaf extract comprises the following steps: cleaning and crushing codonopsis pilosula leaves, adding 20-30 times of deionized water, heating to 80-90 ℃, keeping the temperature for 20-30min, filtering residues, adding 5-10 times of deionized water again, heating to 90-100 ℃, keeping the temperature for 30-40min, filtering residues, combining extracting solutions of the two times, concentrating the extracting solutions to 1/30-/1/50 of the original volume, and crushing the extracting solutions by using a wall-breaking superfine powder technology after spray drying and pulverizing.

Preferably, the preparation method of the codonopsis pilosula leaf extract comprises the following steps: cleaning and crushing codonopsis pilosula leaves, adding 25 times of deionized water, heating to 85 ℃, keeping the temperature for 25min, filtering residues, adding 8 times of deionized water again, heating to 100 ℃, keeping the temperature for 35min, filtering the residues, combining the two extracting solutions, concentrating the extracting solution to 1/40 of the original volume, spray-drying to prepare powder, and crushing the powder by using a wall-broken ultrafine powder technology.

Preferably, the preparation method of the acanthopanax senticosus extract comprises the following steps: cleaning and crushing acanthopanax senticosus, adding 15-25 times of deionized water, sending into an ultrasonic extraction tank for primary extraction, wherein the ultrasonic power is 300-450W, the frequency is 35-45kHz, the extraction time is 0.5-2h, the extraction temperature is 60-80 ℃, extracting an extracting solution after the primary extraction is finished, adding 10-15 times of deionized water again for secondary extraction, keeping the extraction parameters and time unchanged, combining the extracting solutions after the extraction is finished, concentrating the extracting solution to 1/30-/1/50 of the original volume, and crushing the extracting solution by using a wall-breaking ultrafine powder technology after spray drying and powder preparation.

Preferably, the preparation method of the acanthopanax senticosus extract comprises the following steps: cleaning and crushing acanthopanax senticosus, adding 20 times of deionized water, feeding into an ultrasonic extraction tank for primary extraction, wherein the ultrasonic power is 350W, the frequency is 40kHz, the extraction time is 1h, the extraction temperature is 85 ℃, extracting an extracting solution after the primary extraction is finished, adding 10 times of deionized water again for secondary extraction, keeping the extraction parameters and time unchanged, combining the extracting solutions after the secondary extraction is finished, concentrating the extracting solution to 1/40 with the original volume, and crushing the extracting solution by a wall-broken ultrafine powder technology after spray drying and pulverizing.

Preferably, the antiviral Chinese herbal medicine feed additive also comprises any one of scutellaria baicalensis, golden cypress, roasted ephedra herb and fried bitter apricot seed.

Preferably, the scutellaria baicalensis, the golden cypress, the roasted ephedra and the fried bitter apricot seed are added in the invention in parts by weight: 6-8 parts of scutellaria baicalensis, 6-8 parts of golden cypress, 5-7 parts of roasted ephedra or 4-7 parts of fried bitter almond.

The properties and pharmacology of the raw materials of the invention are as follows:

the pine needle powder is prepared from leaves of Pinus massoniana, Pinus pumila, Pinus thunbergii, Pinus densiflora, Pinus sylvestris and Abies fir, and is rich in crude protein, fat, trace elements, vitamins, etc. According to the determination, the pine needle powder contains 7-12% of crude protein, the total content of 18 amino acids such as lysine, aspartic acid and the like reaches 5.5-8.1%, the content of crude fat is 7-12%, the content of nitrogen-free extract is 37%, the ash content is 2-6%, the content of iron, manganese and cobalt are higher than that of common pasture, the pine needle powder contains provitamin A, provitamin B, C, K, E and the like, wherein the content of vitamin C is 650 mg/kg and the content of chlorophyll is 2200 mg/kg, and the pine needle powder is a novel livestock and poultry feed additive and has higher nutritional value. The feed additive can be used as a feed additive for livestock and poultry or directly used for feeding livestock and poultry, not only can save feed and reduce cost, but also has obvious promoting effects on promoting the growth and development of livestock and poultry, enhancing disease resistance, improving reproductive function and the like.

Mirabilite is crystal of mirabilite of sulfate mineral mirabilite family, which is processed and refined. Mainly contains aqueous sodium sulfate (Na2SO4 & 10H 2O). The distribution is distributed in most areas of the country. Has the effects of relaxing bowels with purgative, moistening dryness, softening hard masses, clearing away fire and relieving swelling.

Herba Violae, dry whole herb for use, has effects of clearing heat and detoxicating, and is mainly used for treating carbuncle, furuncle, wind-heat type common cold, bronchitis, hepatitis, enteritis, etc.

The isatis root, named as a traditional Chinese medicine, is a traditional Chinese medicine. Bitter and cold. Has the effects of clearing away heat and toxic materials, cooling blood and relieving sore throat. It is commonly used for epidemic febrile disease, fever, pharyngalgia, epidemic macula, mumps, erysipelas, fever with swollen head, erysipelas, and carbuncle.

Gypsum is monoclinic mineral, is hydrate of calcium sulfate (CaSO4) as main chemical component, is cool, has effects of clearing heat and detoxicating, has no cooling effect on normal body temperature, has a certain antipyretic effect on artificial fever animals, and produces sulfur isotope fractionation under the action of enzyme and APG in the presence of ATP in vivo, so that blood concentration of 34S is increased, thereby playing a role of antivirus.

Rhizoma Dryopteris Crassirhizomatis, named as Chinese medicine. Is prepared from dried rhizome and petiole residue of Dryopteris crassirhizoma of Dryopteridaceae by picking in autumn, removing petiole and fibrous root, removing silt, and clearing away heat and toxic materials, stopping bleeding, and killing parasite. Can be used for treating epidemic common cold, headache due to wind-heat, epidemic heat, speckle, pyocutaneous disease, toxic swelling, metrorrhagia, metrostaxis, hematochezia, and abdominal pain due to parasitic infestation.

Toad skin has the effects of clearing away heat and toxic materials, inducing diuresis and relieving distension. It is indicated for abscess, deep-rooted carbuncle, swelling, scrofula, tumor, malnutritional stagnation, abdominal distension and chronic tracheitis.

Compared with the prior art, the invention has the beneficial effects that: according to the invention, multiple Chinese herbal medicines are compounded with trace elements and vitamins, so that the nutrition of a receptor can be balanced, and multiple trace elements can regulate the metabolism of an organism, promote the growth and development, enhance the disease resistance and improve the utilization rate of the feed; the invention adopts a plurality of raw materials with the effects of clearing away heat and toxic materials, and the concrete effects are that the pine needle powder has obvious promotion effects on promoting the growth and development of livestock and poultry, enhancing disease resistance, improving reproductive function and the like, mirabilite has the effects of relaxing bowels with purgation, moistening dryness and softening hardness, clearing away fire and reducing swelling, gypsum has no cooling effect on normal body temperature and has a certain antipyretic effect on artificial fever animals, and the gypsum generates fractionation of sulfur isotope under the action of enzyme and APG in the presence of ATP in vivo to increase the blood concentration of 34S, thereby playing an antiviral role; by compounding various Chinese herbal medicines, the antiviral performance of the invention can be obviously improved.

Detailed Description

The technical solutions in the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.