阅读说明：本技术 含有可氧化鱼油、迷迭香酸和三价铁的液体营养组合物 (Contain oxidable fish oil, Rosmarinic acid and ferric liquid nutritional compositions ) 是由 N·德威利 M·特皮 A·安特尼普 于 2018-03-27 设计创作，主要内容包括：液体营养组合物具有灰白色颜色与不小于68的Hunter L值,并且包含(a)蛋白质；(b)碳水化合物；(c)含有ω-3多不饱和脂肪酸的可氧化鱼油；(d)迷迭香酸；以及(e)包括正磷酸铁和/或焦磷酸铁的三价铁。所述液体营养组合物表现出减轻的通常在包含鱼油的组合物中遇到的异味和气味。(Liquid nutritional compositions have canescence color and the Hunter L value not less than 68, and include (a) protein；(b) carbohydrate；(c) the oxidable fish oil containing omega-3 polyunsaturated fatty acids；(d) Rosmarinic acid；And (e) include ferric orthophosphate and/or ferric pyrophosphate ferric iron.The liquid nutritional compositions show the usual peculiar smell and smell encountered in the composition comprising fish oil mitigated.)

1. a kind of liquid nutritional compositions, the liquid nutritional compositions have canescence color and include:

(a) protein；

(b) carbohydrate；

(c) the oxidable fish oil containing omega-3 polyunsaturated fatty acids；

(d) Rosmarinic acid；And

(e) include ferric orthophosphate and/or ferric pyrophosphate ferric iron,

Wherein the composition has the Hunter L value not less than 68.

2. liquid nutritional compositions as described in claim 1, wherein the liquid nutritional compositions include 0.0004wt% extremely The Rosmarinic acid of 0.04wt%.

3. liquid nutritional compositions as claimed in claim 1 or 2, wherein the Rosmarinic acid is with water-soluble Rosmarinus officinalis extract Form provides.

4. liquid nutritional compositions as claimed in any one of claims 1-3, wherein the omega-3 polyunsaturated fatty acids packet Include docosahexaenoic acid.

5. such as liquid nutritional compositions of any of claims 1-4, wherein the omega-3 polyunsaturated fatty acids packet Include eicosapentaenoic acid and docosahexaenoic acid.

6. liquid nutritional compositions as claimed in claim 5, the wherein weight of eicosapentaenoic acid and docosahexaenoic acid Than being 1:5 to 5:1.

7. the liquid nutritional compositions also include ω -6 such as liquid nutritional compositions of any of claims 1-6 Polyunsaturated fatty acid.

8. liquid nutritional compositions as claimed in claim 7, wherein the omega 6 polyunsaturated fatty acid includes γ-flax Acid.

9. such as liquid nutritional compositions of any of claims 1-8, the every 237ml deal of liquid nutritional compositions Include about 6 to 60mg ferric orthophosphate and/or ferric pyrophosphate.

10. liquid nutritional compositions as claimed in claim 9, the every 237ml deal of liquid nutritional compositions includes about 1.8 To the iron of 18mg.

11. such as composition of any of claims 1-10, wherein the composition has in the range of -10 to 10 Hunter a value and Hunter b value in the range of -5 to 27.

12. such as liquid nutritional compositions of any of claims 1-11, wherein the composition has 6 to 8 pH Value.

13. such as liquid nutritional compositions of any of claims 1-12, wherein the protein accounts for the liquid battalion The about 2wt% to 15wt% of composition is supported, and the carbohydrate accounts for the about 5wt% of the liquid nutritional compositions extremely 25wt%.

14. such as liquid nutritional compositions of any of claims 1-13, wherein the protein is selected from by following The group of composition: whey protein concentrate, lactalbumin isolate, lactalbumin hydrolysate, acid casein, casein sodium, Calcium caseinate, casein hydrolysate, milk protein concentrate, milk protein isolate, milk protein hydrolysate, takes off Caseins, potassium salts Rouge milk powder, condensed skim milk, soybean protein concentrate, soy protein isolate, soybean protein hydrolyate, pea protein concentration Object, pea protein isolate, pea protein hydrolysate, collagen, collagen isolate, rice protein, potato protein, Earthworm protein, insect protein and their combination.

15. the liquid nutritional compositions as described in any one of claim 1-14, wherein the carbohydrate be selected from by Group consisting of: maltodextrin, hydrolysis starch, glucose polymer, corn syrup, corn-syrup solids, rice source property Carbohydrate, sucrose, glucose, fructose, lactose, high-fructose corn syrup, honey, sugar alcohol, isomaltoketose, relax can it is slow, Pulullan polysaccharide, potato starch, cornstarch, oligofructose, galactooligosaccharide, common oats fibre, soybean fiber, Arab Glue, sodium carboxymethylcellulose, methylcellulose, guar gum, gellan gum, locust bean gum, konjaku flour, hydroxypropyl methyl cellulose, Bassora gum, karaya gum, gum arabic, chitosan, arabogalactan, glucomannans, xanthan gum, alginic acid Salt, pectin, low methoxy pectin, high methoxy pectin, cereal beta glucan, carrageenan, semen pulicariae and their group It closes.

16. the liquid nutritional compositions as described in any one of claim 1-15, the liquid nutritional compositions also include choosing The fat of free group consisting of: coconut oil, fractionated coconut oil, medium chain triglyceride (MCT) oil, canola oil, palm oil, palm fibre Palmitic acid benevolence oil, palm olein and their combination.

17. liquid nutritional compositions as claimed in claim 16, wherein the fat and the oxidable fish oil account for the liquid The about 0.5wt% to 20wt% of body alimentation composition.

18. the liquid nutritional compositions as described in any one of claim 1-17, the liquid nutritional compositions also include to Few a kind of antioxidant selected from the group being made up of: ascorbic acid, ascorbyl palmitate, retinyl palmitate, life Educate phenol, ascorbate, carotenoid, oil-soluble Rosmarinus officinalis extract and their combination.

19. the liquid nutritional compositions as described in any one of claim 1-18, wherein the liquid nutritional compositions have The caloric density of 0.5kcal/mL to 3kcal/mL.

20. the liquid nutritional compositions as described in any one of claim 1-15, wherein the liquid nutritional compositions are in tool There is the aqueous emulsion form of continuous aqueous phase and discontinuous nonaqueous phase.

21. a kind of method of the discoloration mitigated in liquid nutritional compositions and peculiar smell and smell, the liquid nutritional compositions It with canescence color and include protein, carbohydrate and oxidable fish oil containing omega-3 polyunsaturated fatty acids, The method includes in the composition including Rosmarinic acid and ferric iron including ferric orthophosphate and/or ferric pyrophosphate, Described in composition have not less than 68 Hunter L value.

Technical field

The present invention relates to canescence color and contain oxidable fish oil, Rosmarinic acid and ferric liquid nutritional group Close object.In a further embodiment, the present invention relates to mitigate to have canescence color and comprising the liquid of oxidable fish oil battalion The method for supporting the discoloration and peculiar smell and smell in composition.

Background technique

Increasing evidence shows periodically to consume certain amount of unsaturated fatty acid (such as omega-3 polyunsaturated fatty acids) It can provide various health benefits.The profitable source of omega-3 polyunsaturated fatty acids is fish oil.Therefore, many alimentation compositions just quilt It is configured to containing fish oil to provide these unsaturated fatty acids.However, many in these unsaturated fatty acids is all easy to aoxidize, This, which is usually generated, has been described as fishlike smell, coating taste or has in addition made us ill-sorted peculiar smell and smell to be rance.

2015/095545 A1 of WO discloses the alimentation composition comprising oxidable oil such as fish oil and Rosmarinic acid, wherein It adds the Rosmarinic acid and advantageously mitigates peculiar smell and smell in the alimentation composition comprising the oxidable oil.However, It is found that (liquid nutritional of such as vanilla flavored combines for such composition, particularly the liquid nutritional compositions with canescence color Object) certain products become obvious and adversely change colour.Since consumer it is expected that alimentation composition has the wind of reflection composition The color of taste, therefore it is unacceptable that the discoloration in such product, which can make the composition for consumers, because it It is inconsistent to desired coloring relevant with flavor.

Therefore, it is necessary to improved liquid nutritional compositions, the liquid nutritional compositions have canescence color and can Comprising oxidable fish oil and Rosmarinic acid to provide above-mentioned beneficial effect, come the composition for consumer without causing Say unacceptable peculiar smell beastly and smell and discoloration.

Summary of the invention

The present invention overcomes one or more disadvantages of the prior art, and provides and have improved colour stability and good Certain liquid nutritional compositions of good taste and smell.

In one embodiment, the present invention relates to a kind of liquid nutritional compositions, the liquid nutritional compositions have Canescence color and the Hunter L value for being not less than 68, and include (a) protein；(b) carbohydrate；(c) contain ω -3 The oxidable fish oil of polyunsaturated fatty acid；(d) Rosmarinic acid；And (e) include ferric orthophosphate and/or ferric pyrophosphate trivalent Iron.The liquid nutritional compositions show the usual peculiar smell and smell encountered in the composition comprising fish oil mitigated.

In another embodiment, the present invention relates to it is a kind of mitigation liquid nutritional compositions in discoloration and peculiar smell and The method of smell, the liquid nutritional compositions have canescence color and include protein, carbohydrate and containing ω- The oxidable fish oil of 3 polyunsaturated fatty acids.The method includes in the composition comprising Rosmarinic acid and including positive phosphorus The ferric iron of sour iron and/or ferric pyrophosphate, wherein the composition has the Hunter L value not less than 68.

Liquid nutritional compositions and method of the invention show the usual of mitigation and encounter in the composition comprising fish oil Peculiar smell and smell, and avoid changing colour.It has been found that passing through the ferric orthophosphate and pyrophosphoric acid that are provided as amounts of insoluble iron replenishers At least one of iron can combine with the advantages of fish oil in the alimentation composition and provide iron reinforcing and change colour without obvious.Cause This, it is possible to provide there is fish oil and iron to supplement for the liquid nutritional compositions with canescence color, the liquid nutritional compositions Advantage, at the same maintain the composition with the consistent color of composition flavor.

Specific embodiment

Although present general inventive concept allows that its specific reality is described in detail herein in many various forms of embodiments Apply scheme, and it is to be appreciated that the disclosure will be considered as illustration to the principle of present general inventive concept.Therefore, present general inventive concept It is not intended to be limited to specific embodiment illustrated and described herein.

In one embodiment, the present invention relates to liquid nutritional compositions.Unless otherwise stated, as used herein Term " liquid nutritional compositions " cover the nutrient liquid of form of ownership, including emulsifying liquid, and by nutritional powder The liquid for being reconstructed, for example being formed by adding water.The liquid nutritional compositions are suitable for taking use by population.

Unless otherwise stated, otherwise all percentages as used herein, number and than being the weight by total composition Meter.All such weight are all based on activity level when they are related to listed ingredient, and therefore unless otherwise stated, Otherwise the solvent or by-product that in commercially available material may include are not included in.

Term listed herein is only used for description embodiment, and is understood not to generally limit the disclosure. Unless specified otherwise herein, otherwise "/kind (a/an) ", " (the) " and " at least one/kind of (at least one) " can be mutual Change use.In addition, unless context clearly dictates otherwise, otherwise as used in this specification and the appended claims, odd number Form "/kind (a/an) " and " (the) " include its plural form.

In entire this specification, when the range about particularly unique feature of the present invention definition value, the present invention relates to and Clearly each specific sub-ranges are incorporated in.In addition, in entire this specification, when fixed about particularly unique feature of the present invention When adopted one group of substance, the present invention relates to and clearly each specific subgroup is incorporated in.Any specified range or group Should be understood each member for individually referring to range or group and including each of possible subrange and subgroup Shorthand way.

The various embodiments of the alimentation composition of the disclosure can also substantially free of as described herein any optional or Selected ingredient or feature, on condition that remaining alimentation composition still contains all required ingredients or spy as described herein Sign.In this context and unless otherwise stated, otherwise term substantially free means that selected nutrition product contains and is less than The optional member of function amount, typically less than 1 weight % including less than 0.5 weight % including less than 0.1 weight % and also wrapping Include this optional or selected basis of 0 weight %.

Alimentation composition as described herein may include it is following, be made up of or be substantially made up of: such as this paper institute The fundamental for the composition stated and it is described herein or in addition suitable for nutrition product application it is any other or optionally Element.

Unless otherwise indicated herein, otherwise all exemplary implementation schemes, sub- embodiment, specific embodiment and optionally Embodiment be the respective examples embodiment of all embodiments as described herein, sub- embodiment, specific embodiment party Case and optional embodiment.

Unless otherwise specified, term " deal (serving) " as used herein refer to intention by individual primary or The amount consumed in one hour or shorter time.Although the liquid nutritional compositions about 237ml (8 ounces) deal describe this Invention, but as needed, the deal that liquid nutritional compositions of the invention can be smaller or larger provides.It will also be appreciated that Liquid nutritional compositions according to the present invention may include the reconstruct formed by powdered nutritional composition (such as by adding water) Liquid composition.

Unless content combined about reference in context is otherwise noted or clearly illustrates in contrast, otherwise as herein Used in any combination of method or processing step can carry out in any order.

In one embodiment, liquid nutritional compositions of the invention are that storage is stable.Unless otherwise stated, otherwise Term " storing stable " as used herein refer to liquid nutritional compositions stored at 18 DEG C -24 DEG C in packaging and then to It keeps commercially stablizing after 3 months few.It is this packaging be typically included for example by sterile or cracking process to the composition into Row heat sterilization.Storage stability can be measured by any suitable stability indicator, and the index includes but is not limited to disappear The person's of expense acceptance, sedimentation etc..

Alimentation composition of the invention has neutral pH, i.e., about 6 to 8 or more specifically about 6 to 7.5 pH value.Specific In embodiment, the alimentation composition has about 6.5 to 7.2 or more specifically about 6.8 to 7.1 pH value.

Unless otherwise stated, otherwise term " oxidable oil " as used herein refer to due to containing unsaturated fatty acid, Especially polyunsaturated fatty acid and be easy to aoxidize oil.Unless otherwise stated, otherwise term " how unsaturated as used herein Fatty acid " and " PUFA " refer to any more of two or more unsaturations (i.e. two or more carbon-to-carbon double bonds) Unsaturated fatty acid or its source, including short chain (each chain less than about 6 carbon atoms), middle chain (about 6 to about 18 carbon of each chain Atom) and long-chain (each chain has at least about 20 carbon atoms) fatty acid.

In an exemplary embodiment, the liquid nutritional compositions have canescence color and are not less than 68 Hunter L value, and include (a) protein；(b) carbohydrate；(c) containing the oxidable of omega-3 polyunsaturated fatty acids Fish oil；(d) Rosmarinic acid；And (e) include ferric orthophosphate and/or ferric pyrophosphate ferric iron.

In a more particular embodiment, the liquid nutritional compositions with 6 to 8 pH value and/or in having The aqueous emulsion form of continuous aqueous phase and discontinuous nonaqueous phase.

In a more particular embodiment, the liquid nutritional compositions include that the fan of 0.0004wt% to 0.04wt% changes Fragrant acid.In an exemplary embodiment, Rosmarinic acid is provided by water-soluble Rosmarinus officinalis extract.

In a more particular embodiment, the protein accounts for the about 2wt% to 15wt% of the liquid nutritional compositions, The carbohydrate accounts for the about 5wt% to 25wt% of the liquid nutritional compositions.In a more particular embodiment, described Liquid nutritional compositions include the fat (including oxidable oil) of about 0.5wt% to 20wt%.

As mentioned, using the oxidable oil containing unsaturated fatty acid will lead to liquid nutritional compositions with peculiar smell and Smell.Such peculiar smell and smell are frequently described as fishlike smell, coating taste or other rancidity, and usually by oxidable oil Unsaturated fatty acid (especially polyunsaturated fatty acid) oxidation caused by.Rosmarinic acid, which can be used for being effectively protected, to be contained There are the flavor and smell of the liquid nutritional compositions of the oxidable fish oil of unsaturated fatty acid, especially works as liquid nutritional compositions When in aqueous emulsion form and containing omega-3 polyunsaturated fatty acids.Flavor and the smell protection provided by Rosmarinic acid is special Not unexpected, because current techniques point out Rosmarinic acid, (a kind of polar hydrophilic compound) is opened up in water-based emulsion system Existing antioxidant activity is less than non-polar oil soluble compound, such as carnosic acid and carnosol.

It has been found, however, that the composition comprising oxidable fish oil and Rosmarinic acid containing unsaturated fatty acid, especially It is that there are certain products of the liquid nutritional compositions (liquid nutritional compositions of such as vanilla flavored) of canescence color to become obvious And adversely change colour.It has been found that further comprising mineral-reinforced and carrying out iron reinforcing especially with ferrous sulfate In such composition, change colour particularly evident.Using the ferric present composition for including ferric orthophosphate and/or ferric pyrophosphate Show the discoloration of mitigation with method.In some embodiments, the compositions and methods of the invention also unexpectedly provide and change Into flavor attributes.

As mentioned, exemplary fluids alimentation composition includes oxidable containing omega-3 polyunsaturated fatty acids (PUFA) Fish oil.Exemplary ω -3PUFA includes but is not limited to alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA) and two dodecahexaenes Sour (DHA).In certain exemplary implementation schemes, the liquid nutritional compositions include the ω-of 0.005wt% to 5wt% 3PUFA.For example, in certain exemplary implementation schemes, the liquid nutritional compositions include 0.005wt% extremely 4.75wt%, including 0.01wt% to 4.5wt%, 0.05wt% to 4wt%, 0.1wt% to 3.5wt%, 0.5wt% extremely ω-the 3PUFA of 3wt%, 0.75wt% to 2.5wt%, 1wt% to 2wt% or 2wt% to 5wt%.In an exemplary implementation In scheme, ω -3PUFA includes DHA.In an exemplary embodiment, ω -3PUFA includes EPA and DHA.In certain examples Property embodiment in, EPA and DHA exist with the weight ratio of 1:5 to 5:1.For example, in certain embodiments, EPA with The weight ratio of DHA is 1:5 to 5:1, including 1:4 to 4:1,1:3 to 3:1 or 1:2 to 2:1.

In an exemplary embodiment, oxidable oil includes the fish oil containing ω -3PUFA.As used herein, term " fish oil " refers to the oil of the tissue derived from oil-containing fish.Fish oil can by include but is not limited to longfinned tunny, catfish, salmon, black carp, Mackerel, the salt water of long tail anchovy and sardine or fresh-water fishes provide.In certain exemplary implementation schemes, fish oil can be concentration fish Oil.In an exemplary embodiment, fish oil includes EPA and DHA.In an exemplary embodiment, fish oil includes weight Amount is than the EPA and DHA for 1:5 to 5:1 (EPA and DHA).For example, in certain embodiments, the weight ratio of EPA and DHA It is 1:5 to 5:1, including 1:4 to 4:1,1:3 to 3:1 or 1:2 to 2:1.As previously mentioned, ω -3PUFA is (as from fish oil EPA and DHA) it is especially susceptible to aoxidize, and liquid nutritional compositions peculiar smell beastly and smell can be assigned in oxidation (such as fishy odor).

In certain exemplary implementation schemes, the unsaturated fatty acid contained in oxidable oil also includes ω -6PUFA.Show Example property ω -6PUFA includes but is not limited to linoleic acid (LA), gamma-Linolenic acid (GLA), dihomo-gamma-linolenic acid (DGLA) and peanut Tetraenoic acid (AA).In certain exemplary implementation schemes, the liquid nutritional compositions include the ω-of 0.005wt% to 7wt% 6PUFA.For example, in certain exemplary implementation schemes, the liquid nutritional compositions include 0.005wt% to 5wt% ω -6PUFA, including 0.01wt% to 4.5wt%, 0.05wt% to 4wt%, 0.1wt% to 3.5wt%, 0.5wt% extremely ω-the 6PUFA of 3wt%, 0.75wt% to 2.5wt%, 1wt% to 2wt% or 2wt% to 7wt%.In an exemplary implementation In scheme, ω -6PUFA includes gamma-Linolenic acid.

In certain exemplary implementation schemes, unsaturated fatty acid includes at least one ω -3PUFA, such as ALA, EPA and DHA；And at least one ω -6PUFA, such as LA, GLA, DGLA and AA.In an exemplary embodiment, in oxidable oil Unsaturated fatty acid include DHA and GLA.In an exemplary embodiment, the unsaturated fatty acid packet in oxidable oil Containing DHA, GLA and EPA.It is to be appreciated that oxidable oil may include a kind of oxidable oil or a variety of (for example, two kinds, three kinds, four kinds) Oxidable oil.

In order to provide the protection for the oxidation for being directed to oxidable oil and be to mitigate or in addition shelter any peculiar smell and smell, show Example property liquid nutritional compositions include Rosmarinic acid.Rosmarinic acid is a kind of water soluble compound seen in various plants, and And known show antioxidant activity.Only for example, Rosmarinic acid sees sweet basil (Ocimum basilicum/basil), holy sieve Le (Ocimum tenuiflorum/holy basil), lemon balm (Melissa officinalis/lemon balm), fan change Perfume (Rosmarinus officinalis/rosemary), marjoram (Origanum majorana/marjoram), Salvia japonica In (Salvia officinalis/sage), thyme (Thymus vulgaris/thyme) and peppermint.Show at one In example property embodiment, the Rosmarinic acid in the liquid nutritional compositions is provided by water-soluble Rosmarinus officinalis extract.It is exemplary Water-soluble Rosmarinus officinalis extract includes the AquaROX that can be obtained from Vitiva d.d. (Slovenia)^TMExtract, can be from What Naturex, Inc. (South Hackensack, New Jersey) were obtainedWSR extract and can It is obtained from Kalsec, Inc. (Kalamazoo, Michigan)Flavouring.In other certain embodiments In, the Rosmarinic acid in the liquid nutritional compositions can be by coming from one or more above listed plant species or containing fan Repeatedly the water-soluble extractive of the other plant of fragrant acid provides.

In an exemplary embodiment, the liquid nutritional compositions include the fan of 0.0004wt% to 0.04wt% Repeatedly fragrant acid.For example, in certain exemplary implementation schemes, the liquid nutritional compositions include 0.001wt% extremely The Rosmarinic acid of 0.02wt%, including 0.002wt% to 0.012wt%, 0.004wt% to 0.01wt% or 0.01wt% extremely The Rosmarinic acid of 0.04wt%.It has been found that this certain concentration range of Rosmarinic acid particularly effectively mitigates or in addition masking can The peculiar smell and smell generated in the liquid nutritional compositions (especially water-based emulsion) containing oxidable oil.

As discussed previously, it has been found that the combination comprising oxidable fish oil and Rosmarinic acid containing unsaturated fatty acid Certain products of object, particularly the liquid nutritional compositions (liquid nutritional compositions of such as vanilla flavored) with canescence color become It obtains and obviously and adversely changes colour.When being heat-treated to composition, such as in processing and/or sterile or boiling sterilization process In, discoloration usually will increase.It has been found that further comprising mineral-reinforced and carrying out iron especially with ferrous sulfate In the such composition of reinforcing, change colour particularly evident.Using including insoluble source of iron, particularly ferric orthophosphate and/or pyrophosphoric acid The ferric present composition and method of iron show the discoloration of mitigation.Unexpectedly, such insoluble source of iron Iron is provided for alimentation composition to strengthen, and without the discoloration being frequently observed in prior art products, and keeps canescence Product colour.Even if, can also be will not in the composition of heat treatment, the i.e. composition that is sterilized by sterile or cracking process These improvement are obtained in the case where negatively affecting other properties of alimentation composition.For example, ferric orthophosphate and ferric pyrophosphate will not The mouthfeel and taste of apparent precipitating or the pleasant for otherwise interfering the composition are formed in liquid composition, And in certain compositions, the flavor attributes of liquid nutritional compositions can be further improved.

Ferric orthophosphate and/or ferric pyrophosphate are contained in alimentation composition to provide nutrition iron for the composition and strengthen. In a particular embodiment, the every 237ml deal of the alimentation composition includes about 6 to 60mg ferric orthophosphate and/or pyrophosphoric acid Iron.In a further embodiment, the every 237ml deal of the alimentation composition include about 6 to 30mg or more specifically about 6 to The ferric orthophosphate and/or ferric pyrophosphate of 20mg.In a particular embodiment, ferric orthophosphate and/or ferric pyrophosphate are to be enough to provide Every 237ml deal about 1.8 is to 18mg iron or more specifically about 1.8 are contained in the alimentation composition to the amount of 6mg iron.It provides Iron is strengthened, while avoiding the unacceptable discoloration or usual of canescence product (for example, composition of vanilla or banana flavor) Other flavors relevant to canescence or light color.In the other embodiment of alimentation composition, the composition is substantially not Component containing soluble iron, and in a more particular embodiment, the composition contains the less than about soluble iron of 1mg/kg.

It is quantified using anti-discoloration of the Hunter colour code parameter to alimentation composition.Hunter colour code is using variable L, the ternary scale of a and b is exploited for quantitative color and conveys the face between two or more materials in a digital manner Color difference is different.The maximum value of variables L is 100, indicates the substrate (for example, white) of perfect reflection.The minimum value of L is zero and right It should be in black.A value and b value do not have specific numerical value to limit.The positive value of a indicates red, and the negative values greenness of a.The positive value of b Indicate yellow, and the negative values blueness of b.Δ E is to be used in combination to think two kinds of colors (or one with Hunter a, b and L value Kind of color and reference substance) between difference the numerical value of single number description is provided.

In alimentation composition of the invention, ferric orthophosphate and/or ferric pyrophosphate for the composition can effectively provide Hunter L value not less than 68, the canescence color that the composition is substantially maintained in the presence of green-tea extract Amount includes.In a particular embodiment, the alimentation composition of sterilizing has not less than 69 or even more specifically not less than 70 Hunter L value.Such Hunter L value shows that alimentation composition resists significant discoloration.In a further embodiment, the battalion Supporting composition has Hunter a value in the range of -10 to 10 and Hunter b value in the range of -5 to 27.

The liquid nutritional compositions also include protein and carbohydrate, and may include in addition to oxidable oil Fat.The protein of a variety of sources and type, carbohydrate and fat can be used for exemplary fluids nutrition group as described herein It closes in object.

In an exemplary embodiment, the liquid nutritional compositions include about 3 grams of every part of liquid nutritional compositions To 30 grams of protein.For example, in certain exemplary implementation schemes, the liquid nutritional compositions include every part of (example Such as, about 8oz. or 237ml) about 3 grams to 25 grams of liquid nutritional compositions of protein, including every part of liquid nutritional compositions are about 5 grams to 20 grams, about 5 grams to 15 grams, about 5 grams to 10 grams or about 15 grams to 25 grams of protein.

Alternatively, the amount of the protein in the liquid nutritional compositions can be with the weight percent of liquid nutritional compositions (wt%) it indicates.For example, in an exemplary embodiment, protein accounts for the about 2wt% of liquid nutritional compositions extremely 15wt%.In certain exemplary implementation schemes, protein accounts for the about 2wt% to 10wt% of liquid nutritional compositions, including liquid The about 2wt% to 8wt% of body alimentation composition, about 2wt% to 5wt%, about 3wt% to 10wt%, about 5wt% to 10wt% or About 8wt% to 12wt%.

Various protein sources (including a kind of source or be more than a kind of source) can be used for exemplary fluids alimentation composition In.For example, protein source may include but be not limited to complete, hydrolysis and partially hydrolysed protein matter, may originate from it is any Know or other suitable source, such as newborn (such as casein, whey), animal (such as meat, fish), cereal (such as rice, jade Rice), vegetables (such as soybean, pea) and their combination.Protein source, which may also include, to be become known in nutrition product Kilnitamin (being often described as free amino acid) or this amino acid and complete, hydrolysis as described herein and partial hydrolysis egg The combination of white matter.Amino acid can be the amino acid of naturally occurring amino acid or synthesis.

The more specific examples for the protein source being applicable in exemplary fluids alimentation composition as described herein include But it is not limited to dried whole-egg, yolk powder, albumen powder, lactalbumin, whey protein concentrate, lactalbumin isolate, lactalbumin Hydrolysate, acid casein, casein isolate, casein sodium, calcium caseinate, Caseins, potassium salts, casein hydrolysate, Milk protein concentrate, milk protein isolate, milk protein hydrolysate, skimmed milk power, condensed skim milk, full cow's milk, partially or completely Skimmed milk, coconut milk, soybean protein concentrate, soy protein isolate, soybean protein hydrolyate, pea protein concentrate, pea Protein Separation object, pea protein hydrolysate, rice protein concentrate, rice protein isolate, rice protein hydrolysate, collagen egg White, collagen isolate, meat albumen such as beef protein isolate and/or chicken protein isolate, potato protein, earthworm egg White, insect protein and their combination.The alimentation composition may include above listed any individual proteins source or The combination of any one of various protein sources.

In an exemplary embodiment, the liquid nutritional compositions include every part (for example, about 8oz. or 237ml) about 15 grams to 110 grams of liquid nutritional compositions of carbohydrate.For example, in certain exemplary implementation schemes In, the liquid nutritional compositions include about 25 grams to 90 grams of every part of liquid nutritional compositions of carbohydrate, including every part The carbohydrate that about 30 grams to 85 grams, about 35 grams to 75 grams or about 40 grams to 60 grams of liquid nutritional compositions.

Alternatively, the amount of the carbohydrate in the liquid nutritional compositions can be with the weight percent of liquid nutritional compositions Than indicating.For example, in an exemplary embodiment, carbohydrate accounts for the about 5wt% of liquid nutritional compositions extremely 25wt%.In certain exemplary implementation schemes, carbohydrate accounts for the about 5wt% to 20wt% of liquid nutritional compositions, packet Include the about 5wt% to 15wt% of liquid nutritional compositions, about 5wt% to 10wt%, about 10wt% to 25wt%, about 10wt% extremely 20wt%, about 15wt% are to 25wt% or about 20wt% to 25wt%.

Carbohydrate suitable for exemplary fluids alimentation composition as described herein can be simple carbon hydrate Object, complex carbohydrates, its modification or combination.Various carbohydrate sources can be used, as long as source is sought suitable for liquid It supports in composition, and in addition can be with ingredient or feature compatibility selected by any other present in liquid nutritional compositions. Non-limiting example suitable for the carbohydrate source in exemplary fluids nutrient combination as described herein includes malt Dextrin, hydrolysis or the starch of modification, hydrolysis or the cornstarch of modification, glucose polymer (such as polydextrose and dextrin), jade Rice syrup, corn-syrup solids, rice source property carbohydrate (such as rice maltodextrin, coarse rice powder and brown rice syrup), sucrose, Portugal Grape sugar, fructose, lactose, high-fructose corn syrup, honey, sugar alcohol (for example, maltitol, erythritol, D-sorbite), different wheat Bud ketose, relax can slow (sucromalt), pulullan polysaccharide, potato starch, cornstarch, oligofructose, galactooligosaccharide, Common oats fibre, soybean fiber, Arabic gum, sodium carboxymethylcellulose, methylcellulose, guar gum, gellan gum, locust bean gum, Konjaku flour, HYDROXY PROPYL METHYLCELLULOSE, bassora gum, karaya gum, gum arabic, chitosan, arabogalactan, Glucomannans, xanthan gum, alginate, pectin, low methoxy pectin, high methoxy pectin, cereal beta glucan, Irish moss Glue, semen pulicariae, Fibersol^TM, puree, vegetable puree, isomalto-oligosaccharide, monosaccharide, disaccharides, cassava source property carbohydrate, Inulin, other resistant starches and artificial sweetener and their combination.Liquid nutritional compositions may include above listed The combination of any one of what individual carbohydrate source or various carbohydrate sources.

Unless otherwise stated, otherwise term " fat " as used herein refers to lipid, fat, oil and their group It closes.In an exemplary embodiment, the liquid nutritional compositions include every part of (for example, about 8oz. or 237ml) liquid The fat (including oxidable oil) that about 0.5 gram to 50 grams of body alimentation composition.For example, in certain exemplary implementation schemes In, the liquid nutritional compositions include about 1 gram to 46 grams of every part of liquid nutritional compositions of fat, including every part of liquid nutritional About 1.25 grams to 40 grams of composition, about 5 grams to 35 grams, about 10 grams to 25 grams, about 15 grams to 20 grams, v1 grams to 5 grams, about 20 grams extremely 50 grams, about 30 grams to 50 grams or about 40 grams to 50 grams of fat.

Alternatively, the amount of the fat in the liquid nutritional compositions can be with the weight percent table of liquid nutritional compositions Show.For example, in an exemplary embodiment, fat accounts for the pact of liquid nutritional compositions (including oxidable oil) 0.5wt% to 20wt%.In certain exemplary implementation schemes, fat accounts for the about 0.5wt% of liquid nutritional compositions extremely 18wt%, about 0.5wt% to 15wt%, about 0.5wt% to 10wt%, about 0.5wt% including liquid nutritional compositions are extremely 5wt%, about 2wt% are to 8wt%, about 5wt% to 10wt%, about 8wt% to 12wt% or about 12wt% to 18wt%.Certain In other exemplary implementation schemes, fat accounts for the about 15wt% to 20wt% of liquid nutritional compositions (including oxidable oil).

As discussed previously, exemplary fluids alimentation composition includes oxidable fish oil.Therefore, the liquid nutritional combination Object may include any one or more of previously discussed oxidable fish oil as adipose-derived.In addition, in an exemplary implementation In scheme, the liquid nutritional compositions include the combination at least one fat or its source and oxidable fish oil.For example, one In a exemplary implementation scheme, the fat in the liquid nutritional compositions further includes one suitable for liquid nutritional compositions Kind or a variety of other oxidable oil, including but not limited to algal oil, canola oil, linseed oil, borage oil, safflower oil, height Oleic safflower oil, high gamma-linolenic acid (GLA) safflower oil, corn oil, soybean oil, sunflower oil, high oleic sunflower oil and cottonseed oil. Can also with or alternatively include one or more other fat, such as selected from coconut oil, fractionated coconut oil, the acid of medium chain triglyceride three Ester (MCT) oil, palm oil, palm-kernel oil, palm olein and their combination fat.In addition, aforementioned exemplary oil and rouge Any combination of fat can be used in liquid nutritional compositions.

The concentration and relative quantity of protein, carbohydrate and fat in exemplary fluids alimentation composition may depend on Such as anticipated user specific meal demand and significant changes.In an exemplary embodiment, liquid nutritional compositions Be included as the amount of the about 2wt% to 15wt% of liquid nutritional compositions protein, for liquid nutritional compositions about 5wt% extremely The carbohydrate of the amount of 25wt% and for liquid nutritional compositions about 0.5wt% to 12wt% amount fat (including Oxidable oil).In certain exemplary implementation schemes, protein, carbohydrate in exemplary fluids alimentation composition and The percentage or concentration of in addition total calorie that the amount of fat can be provided by specific macronutrient are (for example, every 100mL liquid The grams of the macronutrient of alimentation composition) it indicates, as shown in table 1 below.

^*Fat includes oxidable oil.

A liquid nutritional compositions may depend on such as anticipated user and widely varied.For example, a liquid Alimentation composition can be 30 milliliters (mL) to 500mL (about 1fl oz to about 17fl oz).In certain exemplary implementation schemes In, a liquid nutritional compositions are 110mL to 500mL (about 3.7fl oz to about 17fl oz), including 110mL to 417mL (about 3.7fl oz to about 14fl oz), 120mL to 500mL (about 4fl oz to about 17fl oz), 120mL to 417mL (about 4fl Oz to about 14fl oz), 177mL to 417mL (about 6fl oz to about 14fl oz), (about 7fl oz is to about by 207mL to 296mL 10fl oz), 230mL to 245mL (about 7.7fl oz to about 8.2fl oz), 110mL to 237mL (about 3.7fl oz to about 8fl Oz), 120mL to 237mL (about 4fl oz to about 8fl oz), 110mL to 150mL (about 3.7fl oz to about 5fl oz) or 120mL to 150mL (about 4fl oz to about 5fl oz).Usually as used herein, deal, which can consider, to be intended to disposable side Formula or any amount eaten in one hour or shorter time.

Exemplary fluids alimentation composition as described herein is suitable for providing complementarity, main or unique source of nutrition. In an exemplary embodiment, liquid nutritional compositions have the caloric density of 0.5kcal/mL to 3kcal/mL.In In certain exemplary implementation schemes, liquid nutritional compositions have 0.5kcal/mL to 2.5kcal/mL, including 0.5kcal/mL To 2kcal/mL, 0.5kcal/mL to 1.5kcal/mL, 0.5kcal/mL to 1kcal/mL, 0.5kcal/mL to 0.8kcal/ ML, 1kcal/mL to 3kcal/mL, 1.5kcal/mL to 3kcal/mL, 2kcal/mL to 3kcal/mL or 2.5kcal/mL extremely The caloric density of 3kcal/mL.

In an exemplary embodiment, liquid nutritional compositions also include that at least one in addition to Rosmarinic acid is anti- Oxidant.For example, in certain exemplary implementation schemes, liquid nutritional compositions also include selected from the group being made up of At least one antioxidant: ascorbic acid, ascorbyl palmitate, retinyl palmitate, tocopherol, ascorbate, Carotenoid, oil-soluble Rosmarinus officinalis extract and their combination.Tocopherol suitable for liquid nutritional compositions can To be natural or synthesis, and including but not limited to alpha-tocopherol, d- alpha-tocopherol (RRR- alpha-tocopherol), β-fertility Phenol, Gamma-Tocopherol, Delta-Tocopherol, d, l- alpha-tocopherol (complete-racemic-alpha-tocopherol), tocopherol acetate and their group It closes.Unless otherwise stated, otherwise term " tocopherol " as used herein further includes tocotrienols.Suitable for liquid nutritional group The carotenoid closed in object includes but is not limited to beta carotene, lutein, lycopene, zeaxanthin and their group It closes.Oil-soluble Rosmarinus officinalis extract includes carnosic acid and carnosol as active constituent.Exemplary oil-soluble rosemary mentions Taking object includes the SyneROX that can be obtained from Vitiva d.d. (Slovenia)^TMExtract and can be from Naturex, Inc. (South Hackensack, New Jersey) obtainOSR extract.

In an exemplary embodiment, liquid nutritional compositions also may include the object that can improve liquid nutritional compositions Reason, chemistry, aesthetics or processing characteristics or the one or more other components for serving as other nutrition composition.In addition component is non- Limitative examples include preservative, emulsifier (for example, lecithin), buffer, sweetener (including artificial sweetener (such as sugar Essence, Aspartame, acesulfame potassium K, Sucralose)), colorant, flavoring agent, thickener, stabilizer etc..

In an exemplary embodiment, liquid nutritional compositions also may include vitamin or related nutritional object, non- Limitative examples include vitamin A, vitamin B₁₂, vitamin C, vitamin D, vitamin K, thiamines, riboflavin, pyridoxol, cigarette Acid, folic acid, pantothenic acid, biotin, choline, inositol, its salt and derivative and their combination.Water soluble vitamin can be water-soluble Property vitamin (WSV) pre-composition form addition and/or fat soluble vitamin can be added as needed it is one or more oil carry In body.

In an exemplary embodiment, liquid nutritional compositions also may include minerals, non-limiting example packet Include calcium, phosphorus, magnesium, zinc, manganese, sodium, potassium, molybdenum, chromium, chloride and their combination.

In another embodiment, the present invention relates to a kind of discolorations mitigated in liquid nutritional compositions and peculiar smell and gas The method of taste, the liquid nutritional compositions have canescence color and include protein, carbohydrate and containing ω -3 The oxidable fish oil of polyunsaturated fatty acid.The described method comprises the following steps: in the composition comprising Rosmarinic acid and Ferric iron including ferric orthophosphate and/or ferric pyrophosphate, wherein the composition has the Hunter L value not less than 68.It can root Any exemplary fluids alimentation composition as described herein is prepared according to this illustrative methods.

In a specific embodiment, the method may include that (a) preparation changes comprising protein, carbohydrate and fan The aqueous solution of fragrant acid；(b) preparation includes the oily blend of the oxidable oil containing unsaturated fatty acid；And (c) by the water Solution and the oily blend are mixed to form the liquid nutritional compositions, in the method any suitable Step adds ferric iron.Any exemplary fluids alimentation composition as described herein can be prepared according to this illustrative methods.

In a specific embodiment, the aqueous solution is prepared can include: (a) preparation includes the albumen of water and protein Chylema liquid；(b) preparation includes the carbohydrate slurry of water and carbohydrate；(c) by the protein slurry and the carbon Hydrate slurries are mixed to form the aqueous solution；And Rosmarinic acid source (d) is added to the protein In at least one of slurries, the carbohydrate slurry and described aqueous solution, so that the aqueous solution includes The Rosmarinic acid of 0.0004wt% to 0.2wt%.In certain exemplary implementation schemes, Rosmarinic acid source is added to albumen In at least one of chylema liquid, carbohydrate slurry and aqueous solution so that the aqueous solution include 0.001wt% extremely The Rosmarinic acid of 0.2wt%, including 0.005wt% to 0.15wt%, 0.01wt% to 0.1wt%, 0.05wt% extremely 0.15wt% or 0.1wt% to 0.2wt%.It, can be by heating the desired amount of water to 60 DEG C according to an exemplary implementation scheme To 70 DEG C of temperature and it is mixed into the desired amount of protein and prepares protein slurry.Protein can be as described herein one Kind or multiple proteins, such as casein sodium, caseinhydrolysate acid sodium and whey protein concentrate.According to an exemplary implementation Scheme can prepare carbon by heating the temperature of the desired amount of water to 60 DEG C to 75 DEG C and being mixed into the desired amount of carbohydrate Hydrate slurries.Carbohydrate can be one or more carbohydrate as described herein, such as maltodextrin, sugarcane Sugar, oligofructose, soybean fiber, Arabic gum, gellan gum etc..In addition, carbohydrate slurry may include minerals (including three Valence iron), preservative, stabilizer, thickener etc..

In an exemplary embodiment, Rosmarinic acid source is added in protein slurry, then by by egg White matter slurries and carbohydrate slurry are mixed together to form aqueous solution.In an exemplary embodiment, fan is changed Fragrant acid source is added in carbohydrate slurry, then by mixing protein slurry and carbohydrate slurry To form aqueous solution.In an exemplary embodiment, Rosmarinic acid source is added to by by protein slurry and carbon Hydrate slurries mix and in the aqueous solutions that are formed.Rosmarinic acid source can be any source as described herein. In an exemplary embodiment, Rosmarinic acid source is water-soluble Rosmarinus officinalis extract.

It, can be by heating the desired amount of fat and oxidable oil to 25 DEG C to 35 DEG C according to an exemplary implementation scheme Temperature and the emulsifier of such as lecithin is mixed into prepare the oily blend comprising the oxidable oil containing unsaturated fatty acid. In certain exemplary implementation schemes, the oil blend also includes at least one antioxidant.Fatty and oxidable oil can be with It is one or more fat as described herein and oxidable oil, such as fish oil, fractionated coconut oil, canola oil, soybean oil.It is similar Ground, at least one antioxidant can be one or more antioxidants as described herein, such as ascorbyl palmitate, mixing Tocopherol, oil-soluble Rosmarinus officinalis extract etc..In addition, oily blend also may include fat soluble vitamin, including but not limited to tie up Raw element A, vitamin D, vitamin E, vitamin K and their combination.

It is to be appreciated that the discussion can be applied equally to basis when discussing liquid nutritional compositions disclosed herein The alimentation composition that illustrative methods as described herein generate.In other words, in certain exemplary implementation schemes, exemplary side Method can be considered as the method for being used to prepare exemplary fluids alimentation composition as described herein.However, it should also be appreciated that this paper institute The illustrative methods stated can also be used in preparation and be different from exemplary fluids nutrient combination as described herein in one or more aspects The alimentation composition of object.

In an exemplary embodiment, aqueous solution and oily blend are blended together under heating and stirring with shape At liquid nutritional compositions.In an exemplary embodiment, the pH of liquid nutritional compositions can be adjusted to required pH model Enclose (such as 6.8 to 7).In an exemplary embodiment, liquid nutritional compositions are heat-treated and are homogenized.Citing For, heat treatment can for example pass through high temperature, short time (" HTST ") processing or superelevation for making liquid nutritional compositions sterilize Warm working (" UHT ") Lai Jinhang.After being heat-treated and homogenizing, it can add water soluble vitamin solution (if applicable), and And adjustable pH (if necessary), flavoring agent can be added, and any additional water can be added to adjust solid content to required Range.At this point, liquid nutritional compositions it is optionally packaged and according to any suitable sterilization technology (such as anti-corrosion, boiling, Hot charging fills out, is chemical, irradiating and sterilizing filtration techniques) it sterilizes.