阅读说明：本技术 一种治疗腰腿扭伤的药物及其制备方法和应用 (A kind of drug and its preparation method and application for treating waist-leg strain ) 是由 关瑜珠 于 2018-05-22 设计创作，主要内容包括：本发明公开了一种治疗腰腿扭伤的药物及其制备方法和应用,按照重量的原料组成包括：蛇蜕15-35g,薄荷10-50g,细辛30-70g,丹参10-18g,天然磁石1-5g；将蛇蜕进行破碎,分别依次过50目筛和90目筛,置于装有乙醇的PE袋中进行辐照,辐照之后烘干、磨碎；采用CO2超临界萃取法对将薄荷和细辛进行分别萃取；将丹参粉碎处理,加乙醇,过滤,保留药渣和上清液；将天然磁石粉碎,过筛,炒制；将蛇蜕药末与薄荷以及细辛萃取物混合,再混合丹参混合液,天然磁石粉,薄荷和细辛的粉碎药末,搅拌,即可制得一种治疗腰腿扭伤的药物；本发明在天然磁石与其他中药的科学配伍下,对腰腿扭伤疗效确切、稳定,见效快、治愈率高、无毒副作用、治愈后不复发,用药安全,用药量少。(The invention discloses a kind of drugs and its preparation method and application for treating waist-leg strain, include: snake slough 15-35g, peppermint 10-50g, asarum 30-70g, Radix Salviae Miltiorrhizae 10-18g, loadstone 1-5g according to the raw material composition of weight；Snake slough is crushed, 50 meshes and 90 meshes is successively crossed respectively, is placed in the PE bag equipped with ethyl alcohol and is irradiated, dries, grind after irradiation；It is extracted respectively using CO2 supercritical extraction to by peppermint and asarum；By Radix Salviae Miltiorrhizae pulverization process, add ethyl alcohol, filter, retains the dregs of a decoction and supernatant；Loadstone is crushed, is sieved, frying；Snake slough medicine end is mixed with peppermint and asarum extract, remixes Radix Salviae Miltiorrhizae mixed liquor, loadstone powder, the crushing medicine end of peppermint and asarum stirs, can be prepared by a kind of drug for treating waist-leg strain；The present invention under the scientific compatibility of loadstone and other Chinese medicines, to waist-leg sprain it is curative for effect, stablize, quick, cure rate is high, has no toxic side effect, non-relapse after healing, drug safety, dosage is few.)

1. a kind of drug for treating waist-leg strain, which is characterized in that forming according to the raw material of weight includes: snake slough 15-35g, thin Lotus 10-50g, asarum 30-70g, Radix Salviae Miltiorrhizae 10-18g, loadstone 1-5g.

2. a kind of drug for treating waist-leg strain according to claim 1, which is characterized in that formed according to the raw material of weight It include: snake slough 20-30g, peppermint 20-40g, asarum 40-60g, Radix Salviae Miltiorrhizae 12-16g, loadstone 2-4g.

3. a kind of drug for treating waist-leg strain according to claim 1, which is characterized in that formed according to the raw material of weight It include: snake slough 25g, peppermint 30g, asarum 50g, Radix Salviae Miltiorrhizae 146g, loadstone 3g.

4. a kind of preparation method of drug for treating waist-leg strain according to claim 1, which is characterized in that including following Step:

Snake slough is crushed, 50 meshes and 90 meshes is successively crossed respectively, obtains medicine of the particle size between 90 mesh and 50 mesh Above-mentioned manufactured herb in granule form powder is placed in the PE bag equipped with ethyl alcohol and irradiates by material particle powder, and radiation mode is electricity Beamlet irradiation, irradiation dose are 110~150Gy/s, and irradiation time is 3 hours, and the medicinal powder after irradiating is placed in temperature and is It dries in 80 DEG C of baking oven, is ground after natural cooling, repeat to be sieved, obtain the molecule medicine between 110 mesh~90 mesh Material powder；

It is extracted respectively using CO2 supercritical extraction to by peppermint and asarum, extracting pressure is 40MPa~80MPa, extraction Temperature is 30 DEG C~70 DEG C, 3~5h of extraction time, and extract stores classifiedly spare；Then the dregs of a decoction are respectively placed in 60 DEG C~80 DEG C baking oven in dry, after natural cooling, then medication stone roller crushed, smashed medicine end stores classifiedly spare；

By Radix Salviae Miltiorrhizae pulverization process, 1-3 times of weight of 60% ethyl alcohol is then added, stands 3h, then filters, the reservation dregs of a decoction and upper Clear liquid, the water of 6-10 times of dregs of a decoction add weight, boils, and then uses instead and is cooked by slow fire 10min, then natural cooling, mixes after cooling Supernatant stirs 1-2min, retains mixed liquor；

Loadstone is crushed, 180 meshes are then crossed, in 90-100 DEG C of progress frying 5-8min, loadstone powder is made；

Snake slough medicine end is mixed with peppermint and asarum extract, Radix Salviae Miltiorrhizae mixed liquor is remixed, is stirred at 30-50 DEG C, 20-28min is stirred, loadstone powder is then added, temperature is improved to 60-70 DEG C, continues to stir 8-10min, then naturally cold But, the crushing medicine end of peppermint and asarum is added during natural cooling, and continues to stir 3-5min, after ten thousand but cool down, i.e., A kind of drug for treating waist-leg strain can be made.

5. a kind of application of drug for treating waist-leg strain according to claim 1 to 3, which is characterized in that be used to prepare and control Treat the drug that waist-leg is sprained.

Technical field

The present invention relates to waist-legs to sprain therapeutic agent technical field, specially a kind of drug and its system for treating waist-leg strain Preparation Method and application.

Background technique

With the continuous variation of Chinese society population structure, the population ratio of the elderly is increasingly heavier, the elderly's population Amount is continuous to be increased.And the elderly is usually handicapped, it is easy to there is the case where spraining of falling, especially in rain and snow weather, Such case is even more to happen occasionally, and the generation of this strain accident is not only more in life to bring inconvenience, meanwhile, also to from The huge body of body bring decocts, and influences the body and mental health of the elderly.

Currently, the medicament categories that the treatment waist-leg occurred in the market is sprained are various, but therapeutic effect is extremely limited, treatment Period is long, is unfavorable for the recovery of patient's state of an illness, and patient is sprained pain by waist-leg for a long time, is brought to the physical and mental health of patient Huge psychology pharmacology, further influences taking a turn for the better for the state of an illness.

Summary of the invention

The purpose of the present invention is to provide a kind of drugs and its preparation method and application for treating waist-leg strain, on solving State the problem of proposing in background technique.

To achieve the above object, the invention provides the following technical scheme:

A kind of drug for treating waist-leg strain includes: snake slough 15-35g, peppermint 10-50g, asarum according to the raw material composition of weight 30-70g, Radix Salviae Miltiorrhizae 10-18g, loadstone 1-5g.

Further: the drug that the treatment waist-leg is sprained includes: snake slough 20-30g according to the raw material composition of weight, thin Lotus 20-40g, asarum 40-60g, Radix Salviae Miltiorrhizae 12-16g, loadstone 2-4g.

Further: the drug that the treatment waist-leg is sprained includes: snake slough 25g, peppermint according to the raw material composition of weight 30g, asarum 50g, Radix Salviae Miltiorrhizae 146g, loadstone 3g.

It is a further object of the present invention to provide a kind of preparation methods of drug for treating waist-leg strain, comprising the following steps:

1) snake slough is crushed, successively crosses 50 meshes and 90 meshes respectively, obtains particle size between 90 mesh and 50 mesh Above-mentioned manufactured herb in granule form powder is placed in the PE bag equipped with ethyl alcohol and irradiates by herb in granule form powder, and radiation mode is Electron beam irradiation, irradiation dose are 110~150Gy/s, and irradiation time is 3 hours, and the medicinal powder after irradiating is placed in temperature To be dried in 80 DEG C of baking ovens, is ground after natural cooling, repeat to be sieved, obtain the molecule between 110 mesh~90 mesh Medicinal powder；

2) it is extracted respectively using CO2 supercritical extraction to by peppermint and asarum, extracting pressure is 40MPa~80MPa, extraction Taking temperature is 30 DEG C~70 DEG C, 3~5h of extraction time, and extract stores classifiedly spare；Then by the dregs of a decoction be respectively placed in 60 DEG C~ It is dried in 80 DEG C of baking oven, after natural cooling, then medication stone roller is crushed, and smashed medicine end stores classifiedly spare；

3) by Radix Salviae Miltiorrhizae pulverization process, 1-3 times of weight of 60% ethyl alcohol is then added, stands 3h, then filters, retain the dregs of a decoction with Supernatant, the water of 6-10 times of dregs of a decoction add weight, boils, and then uses instead and is cooked by slow fire 10min, then natural cooling, mixes after cooling Clear liquid is closed, 1-2min is stirred, retains mixed liquor；

4) loadstone is crushed, then crosses 180 meshes, in 90-100 DEG C of progress frying 5-8min, loadstone powder is made；

5) snake slough medicine end is mixed with peppermint and asarum extract, remixes Radix Salviae Miltiorrhizae mixed liquor, stirred at 30-50 DEG C It mixes, stirs 20-28min, loadstone powder is then added, temperature is improved to 60-70 DEG C, continues to stir 8-10min, then natural It is cooling, the crushing medicine end of peppermint and asarum is added during natural cooling, and continue to stir 3-5min, after ten thousand but cool down, It can be prepared by a kind of drug for treating waist-leg strain.

It is yet another object of the invention to provide application of the drug in preparation treatment waist-leg is sprained.

Snake slough, this product is cylindrical, and multiple pressure is flat and shrinkage, complete person are similar to snake, long up to 1m or more.Back silver gray or Light taupe brown, glossy, squama mark diamond shape or ellipse, joining place is white, slightly shirring or concave；Abdomen milky shows slightly yellow Color, squama mark rectangle are arranged in imbricate.Body is light, and matter is micro- tough, and hand has pinched lubrication sense and elasticity, gently crumples, rustles. The micro- raw meat of gas, it is lightly seasoned or micro- salty.Medicinal part, animal slough off under drying epidermis film.Nature and flavor, taste is salty, sweet, mild-natured.Channel tropism, Liver Channel. Function has wind-dispelling, and screen, the effect of removing toxic substances are moved back in arresting convulsion.It cures mainly, is used for child convulsion, spasm of twitching, ocular, sore throat, treatment is swollen, skin Skin itch.

Peppermint, peppermint are Chinese conventional Chinese medicines, and young tender stem tip can make vegetable edible, and herb can be used as medicine again, and cure cold fever laryngalgia, Headache, conjunctival congestion with ophthalmalgia, myalgia, itchy skin with rubella, the diseases such as measles without adequate eruption are furthermore also effective to carbuncle, subcutaneous ulcer, scabies, tinea, dermatitis rhus. Peppermint contains menthol, the substance can fresh breath and have a variety of pharmacological properties, can be relieved abdominal pain, gall-bladder problem such as spasm, also have There are antisepsis and sterilization, diuresis, resolving sputum, stomach invigorating and aid digestion and other effects.Large amounts of food peppermint can lead to insomnia, but low dose of edible It conduces to sleep.

Asarum also known as thin ginseng, bowl of a pipe flower.Belong to Aristolochiaceae, herbaceos perennial.For conventional Chinese medicine." legendary god of farming's book on Chinese herbal medicine Through " it is classified as top grade.Because its root is thin, acrid flavour, therefore gain the name.This kind of all herbal medicine.Major function, relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping lead to Key, warming lung and resolving fluid.For anemofrigid cold, have a headache, toothache, nasal congestion, allergic rhinitis, nasosinusitis, rheumatic arthralgia, sputum cough.(1) it sends out Dispersing wind and cold: for headache caused by anemofrigid cold or chill, Chinese ephedra, rhizoma ligustici can be matched.(2) antalgic: for cold-evil enter network it Muscle arthralgia.(3) warming cold phlegm: to stop up the chronic bronchitis contained for dilute phlegm.(4) preferably lead to lung key: for rhinitis, nasal sinus It is scorching.

Radix Salviae Miltiorrhizae, medicinal part, the root of plant.Nature and flavor, bitter are slightly cold.Channel tropism, converge to heart and liver channels.Effect, promoting blood circulation lead to Meridian and relieving pain, relieving restlessness and restlessness, cool blood to disappear carbuncle.Cure mainly, be used for chest impediment and cardialgia, stomach duct and abdomen hypochondriac pain, lump in the abdomen lump in the abdomen accumulation, hot numbness pain, it is vexed not It sleeps, irregular menstruation, dysmenorrhea menostasis, sore swell and ache curative.

Loadstone, function is pungent, salty, puts down.Tranquillizing the mind by relieving convulsion, suppressing hyper-yang to enchance respiration.Cure mainly, for vertigo, tinnitus, deafness, It is empty asthma, frightened epilepsy, seized with terror secondary.Decoction for oral administration, or enter ball, dissipate；External application, which is ground, to be dressed.

Compared with prior art, science of the present invention in loadstone and other Chinese medicines (snake slough, peppermint, asarum, Radix Salviae Miltiorrhizae) Under compatibility, to waist-leg sprain it is curative for effect, stablize, quick, cure rate is high, has no toxic side effect, non-relapse after healing, medication peace Entirely, dosage is few；And present invention materials are extensive, preparation process is simple, easy to operate, production cost is low.

Specific embodiment

Below in conjunction with the embodiment of the present invention, technical scheme in the embodiment of the invention is clearly and completely described, Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based in the present invention Embodiment, every other embodiment obtained by those of ordinary skill in the art without making creative efforts, all Belong to the scope of protection of the invention.