阅读说明：本技术 治疗癌症的vegfr-2 car免疫细胞 (The VEGFR-2 CAR immunocyte for the treatment of cancer ) 是由 巢立文 黄华友 田保民 玛尼·黛安·乌格 于 2018-01-04 设计创作，主要内容包括：提供了使用CAR治疗人类癌症的组合物和方法。本发明包括工程化的CAR(嵌合受体抗原)和表达对VEGFR具有高亲和力的此类CAR的基因修饰的免疫细胞。更具体地,细胞是识别实体瘤上VEGFR-2的CAR-T细胞,其用途,其组合物及其制备方法。本发明包括靶向肿瘤血管生成的治疗VEGFR-2依赖的癌症的治疗方法。嵌合抗原受体(CAR),其与VEGFR-2、VEGFR-2的表位或片段、或VEGFR-2的变体结合。(Provide the composition and method using CAR treatment human cancer.The present invention includes the immunocyte of the gene modification of the such CAR of the CAR (Chimerical receptor antigen) and expression of engineering to VEGFR with high-affinity.More specifically, cell is the CAR-T cell for identifying VEGFR-2 on solid tumor, purposes, its composition and preparation method thereof.The present invention includes the treatment method for the cancer that the treatment VEGFR-2 of target tumor angiogenesis is relied on.Chimeric antigen receptor (CAR), in conjunction with the variant of the epitope of VEGFR-2, VEGFR-2 or segment or VEGFR-2.)