同时具有BET Bromodomain蛋白抑制和PD-L1基因调控作用的化合物
阅读说明:本技术 同时具有BET Bromodomain蛋白抑制和PD-L1基因调控作用的化合物 (Compound with BET Bromodomain protein inhibition and PD-L1 gene regulation functions ) 是由 沈春莉 朱玉川 王廷 吴成德 陈曙辉 于 2020-03-06 设计创作,主要内容包括:一类同时具有BET Bromodomain蛋白抑制活性和调控PD-L1基因表达的化合物,及其在制备治疗与BET Bromodomain蛋白抑制剂及PD-L1基因表达相关肿瘤疾病的药物中的应用。具体公开了式(1)所示化合物、其异构体及其药学上可接受的盐。(A compound having both BET Bromodomain protein inhibitory activity and PD-L1 gene expression regulation, and its application in preparing medicines for treating tumor diseases related to BET Bromodomain protein inhibitors and PD-L1 gene expression. Specifically disclosed are a compound represented by the formula (1), an isomer thereof, and a pharmaceutically acceptable salt thereof.)