阅读说明：本技术 作为减少或预防转移、治疗自身免疫和炎性病症以及重新平衡免疫环境和失调的小生境的平台的基因修饰的造血干细胞和祖细胞(hspc)及间充质细胞 (Genetically modified Hematopoietic Stem and Progenitor Cells (HSPCs) and mesenchymal cells as platforms for reduction or prevention of metastasis, treatment of autoimmune and inflammatory disorders, a) 是由 罗珊德拉·N·卡普兰 萨比纳·A·克拉茨梅尔 丹尼尔·W·贝里 秦海瑛 于 2020-02-10 设计创作，主要内容包括：提供了包含基因修饰的造血干细胞和祖细胞(HSPC)和/或基因修饰的间充质细胞的组合物,其中所述细胞含有包含转基因的载体,以及产生所述基因修饰的HSPC和基因修饰的间充质细胞的方法,以及治疗或预防癌症(例如转移)和神经变性病况、自身免疫病症和炎性病症的方法。(Compositions comprising genetically modified Hematopoietic Stem and Progenitor Cells (HSPCs) and/or genetically modified mesenchymal cells, wherein the cells contain a vector comprising a transgene, and methods of producing the genetically modified HSPCs and genetically modified mesenchymal cells, and methods of treating or preventing cancer (e.g., metastasis) and neurodegenerative conditions, autoimmune disorders, and inflammatory disorders are provided.)