阅读说明：本技术 一种持久留香的头发处理香料组合物 (A hair treatment perfume composition with lasting fragrance ) 是由 王天义 梁立冬 张政 王毅 仝丹丹 于 2021-09-24 设计创作，主要内容包括：本发明公开了一种持久留香的头发处理香料组合物,属于日用化工技术领域。且所述香料组合物包括香料缓释颗粒、羟乙基纤维素、硬脂酰胺丙基二甲基叔胺、何首乌乙醇提取浸膏、异鲸蜡醇聚醚-20和去离子水。所述香料缓释颗粒是以强化改性壳聚糖为包裹基材,复合香料为芯材。所述疏水强化改性首先对壳聚糖进行了疏水改性,增加壳聚糖分子链与复合香料的相容性,提高其对复合香料的包裹性能；蚕丝蛋白的多肽链与头发具有良好的亲和性,进而使获得的香料缓释颗粒能够附着在头发上；因此,通过包裹膜材与蚕丝蛋白的共同作用下,达到香料缓释颗粒附着在头发上,缓释香料,进而达到持久留香的目的。(The invention discloses a hair treatment spice composition with lasting fragrance, and belongs to the technical field of daily-use chemical industry. And the perfume composition comprises perfume slow-release particles, hydroxyethyl cellulose, stearamidopropyl dimethyl tertiary amine, polygonum multiflorum ethanol extract, isocetyl polyether-20 and deionized water. The slow-release particles of the spice take the reinforced modified chitosan as a wrapping base material and take the composite spice as a core material. The hydrophobic reinforced modification is to perform hydrophobic modification on chitosan, so that the compatibility of a chitosan molecular chain and the composite perfume is improved, and the wrapping performance of the chitosan molecular chain on the composite perfume is improved; the polypeptide chain of the fibroin has good affinity with hair, so that the obtained perfume slow-release particles can be attached to the hair; therefore, under the combined action of the wrapping film material and the fibroin, the slow-release particles of the spice are attached to the hair, the spice is slowly released, and the aim of lasting fragrance is fulfilled.)

1. A long lasting fragrance hair treatment fragrance composition characterized by: the method comprises the following raw materials: perfume slow release particles, hydroxyethyl cellulose, stearamidopropyl dimethyl tertiary amine, polygonum multiflorum ethanol extract, isocetyl polyether-20 and deionized water;

the slow-release perfume particle is prepared by the following steps:

stirring the enhanced modified chitosan, sodium dodecyl sulfate, compound perfume, ethanol and deionized water at 50-65 deg.C for 30-70min to obtain mixed solution, cooling to room temperature, packaging the mixed solution, lyophilizing, and demolding to obtain perfume sustained release granule.

2. A long-lasting fragrance hair treatment fragrance composition according to claim 1, characterized in that: the hair treatment perfume composition comprises the following raw materials in parts by weight: 8-17 parts of perfume slow-release particles, 1.5-5.5 parts of hydroxyethyl cellulose, 1-3.5 parts of stearamidopropyl dimethyl tertiary amine, 0.5-4.5 parts of polygonum multiflorum ethanol extract, 201-3.5 parts of isocetyl polyether and 75-95 parts of deionized water.

3. A long-lasting fragrance hair treatment fragrance composition according to claim 1, characterized in that: the slow-release perfume particle comprises the following raw materials in parts by weight: 0.5-1.5 parts of compound spice, 20-35 parts of reinforced modified chitosan, 1.5-4 parts of sodium dodecyl sulfate, 75-100 parts of deionized water and 0.1-1.5 parts of ethanol.

4. A long-lasting fragrance hair treatment fragrance composition according to claim 3, characterized in that: the compound spice is composed of gamma-decalactone and delta-decalactone according to the mass ratio of 0.1-1.3: 0.3-1.

5. A long-lasting fragrance hair treatment fragrance composition according to claim 3, characterized in that: the reinforced modified chitosan is prepared by the following steps:

s1, dissolving chitosan in 7% acetic acid solution by mass, adding dimethyl sulfoxide for dilution after complete dissolution, then adding succinic anhydride, controlling the reaction temperature at 62 ℃, stirring at 500r/min for 8h, and performing post-treatment to obtain acylated chitosan;

and S2, dissolving the acylated chitosan in MES buffer solution with the pH value of 6, adding a mixture of NHS and EDC & HCl, stirring for 30-50min to obtain a mixed solution, adding a DMF (dimethyl formamide) solution of fibroin in a nitrogen atmosphere, stirring for reacting for 3 days at room temperature, and performing post-treatment to obtain the reinforced modified chitosan.

6. A long-lasting fragrance hair treatment fragrance composition according to claim 5, characterized in that: in the step S1, the dosage ratio of the chitosan, the acetic acid solution, the dimethyl sulfoxide and the succinic anhydride is 100 g: 100mL of: 100mL of: 20-35 g.

7. A long-lasting fragrance hair treatment fragrance composition according to claim 5, characterized in that: in the step S2, the dosage ratio of the acylated chitosan, the MES buffer solution, the mixture of NHS and EDC & HCl and the fibroin is 5 g: 50-80 mL: 1.5-3 g: 1-1.5 g.

8. A long-lasting fragrance hair treatment fragrance composition according to claim 1, characterized in that: is prepared by the following steps:

adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring at the temperature of 40-50 ℃ for 20-40min at 700r/min with 400-.

Technical Field

The invention belongs to the technical field of daily-use chemical industry, and particularly relates to a hair treatment spice composition with lasting fragrance.

Background

The feel of the hair is of paramount importance to the consumer. Desirable tactile properties of hair include smoothness, softness, moisturization, and cleanliness. The existing hair treatment substances are often added with essence or spice or essential oil to add the feeling of experience except the hair touch, namely fragrance retention. However, the conventional hair treatment fragrance composition has a relatively short fragrance-retaining time, and sometimes has a strong fragrance immediately after use, and the fragrance tends to become weak with the lapse of time. This is due to the fact that the perfume in the existing hair treatment perfume composition is often added in a direct manner, and it is difficult to effectively prolong the perfume-remaining time. And most flavors and fragrances are sensitive and unstable due to the presence of reactive groups or low solubility, resulting in loss of fragrance.

Accordingly, the present invention provides a hair treatment fragrance composition that is long lasting.

Disclosure of Invention

It is an object of the present invention to provide a hair treatment fragrance composition with long lasting fragrance to solve the problems mentioned in the background above.

The purpose of the invention can be realized by the following technical scheme:

a hair treatment perfume composition with lasting fragrance comprises the following raw materials in parts by weight: 8-17 parts of perfume slow-release particles, 1.5-5.5 parts of hydroxyethyl cellulose, 1-3.5 parts of stearamidopropyl dimethyl tertiary amine, 0.5-4.5 parts of polygonum multiflorum ethanol extract, 201-3.5 parts of isocetyl polyether and 75-95 parts of deionized water.

Further, the slow-release perfume particle comprises the following components in parts by weight: 0.5-1.5 parts of compound spice, 20-35 parts of reinforced modified chitosan, 1.5-4 parts of sodium dodecyl sulfate, 75-100 parts of deionized water and 0.1-1.5 parts of ethanol.

Further, the compound perfume is composed of gamma decalactone and delta decalactone according to the mass ratio of 0.1-1.3: 0.3-1.

Further, the reinforced modified chitosan is prepared by the following steps:

s1, dissolving chitosan in 7% acetic acid solution by mass, adding dimethyl sulfoxide for dilution after complete dissolution, then adding succinic anhydride, controlling the reaction temperature to be 62 ℃, stirring at 500r/min for 8 hours, transferring the reaction solution into a dialysis bag with cut-off molecular weight of 3000, dialyzing with deionized water for 3 days, and drying in vacuum at 0 ℃ to obtain acylated chitosan, wherein the dosage ratio of chitosan, acetic acid solution, dimethyl sulfoxide and succinic anhydride is 100 g: 100mL of: 100mL of: 20-35 g;

in the reaction, succinic anhydride is utilized to carry out acylation hydrophobic modification on chitosan, so that the compatibility of a chitosan molecular chain and the compound perfume is improved, the wrapping performance of the chitosan molecular chain on the compound perfume is improved, and meanwhile, carboxyl is introduced to lay a foundation for subsequent reaction;

s2, dissolving acylated chitosan in MES buffer solution (0.1M) with the pH value of 6, adding a mixture of NHS and EDC & HCl, stirring for 30-50min to obtain a mixed solution, adding fibroin DMF solution in nitrogen atmosphere, stirring for reaction at room temperature for 3 days, neutralizing with 0.1M sodium hydroxide solution, transferring into a dialysis bag with the cutoff molecular weight of 4000-7000, dialyzing with deionized water for 2 days, and freeze-drying to obtain the reinforced modified chitosan, wherein the dosage ratio of the acylated chitosan, the MES buffer solution, the mixture of NHS and EDC & HCl, and the fibroin is 5 g: 50-80 mL: 1.5-3 g: 1-1.5 g.

The fibroin and the chitosan are grafted in the reaction, the toughness of the fibroin is utilized, the mechanical strength of the chitosan film forming is enhanced, the wrapping capacity and the slow release capacity of the chitosan on the composite perfume are enhanced, meanwhile, the polypeptide chain contained in the molecular structure of the fibroin is utilized, the affinity with the hair is good, and the obtained perfume slow release particles can be attached to the hair.

Further, the perfume sustained-release particle is prepared by the following method:

stirring the enhanced modified chitosan, sodium dodecyl sulfate, composite perfume, ethanol and deionized water at 50-65 deg.C for 30-70min to obtain mixed solution, cooling to room temperature, pouring the mixed solution into a mold, subpackaging, freeze drying, and demolding to obtain perfume sustained release granule.

In the reaction, the gel effect of the reinforced modified chitosan is utilized, the molecular chain of the reinforced modified chitosan contains a chitosan molecular chain and a polypeptide molecular chain, and the molecules are subjected to sol gelation under the action of sodium dodecyl sulfate to finish the wrapping of the composite perfume, so that the perfume slow-release particles are formed, and the effects of protecting and slowly releasing the perfume are formed.

A hair treatment fragrance composition with long lasting fragrance is prepared by the following steps:

adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring at the temperature of 40-50 ℃ for 20-40min at 700r/min with 400-.

The invention has the beneficial effects that:

the hair treatment spice composition provided by the invention is added with the spice slow-release particles to achieve the aim of lasting fragrance, the spice slow-release particles take reinforced modified chitosan as a wrapping base material and composite spice as a core material, and in the invention, the chitosan is subjected to hydrophobic modification at first, so that the compatibility of chitosan molecular chains and the composite spice is increased, and the wrapping performance of the chitosan molecular chains and the composite spice is improved; grafting the fibroin and the chitosan again, and enhancing the mechanical strength of the chitosan film by utilizing the toughness of the fibroin so as to enhance the mechanical property of the wrapping film and improve the wrapping capacity and the slow release capacity of the wrapping film on the compound spice; meanwhile, the polypeptide chain of the fibroin has good affinity with hair, so that the obtained perfume slow-release particles can be attached to the hair; therefore, under the combined action of the wrapping film material and the fibroin, the slow-release particles of the spice are attached to the hair, the spice is slowly released, and the aim of lasting fragrance is fulfilled.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

the reinforced modified chitosan is prepared by the following steps:

s1, dissolving 100g of chitosan in 100mL of acetic acid solution with the mass fraction of 7%, after complete dissolution, adding 100mL of dimethyl sulfoxide for dilution, then adding 35g of succinic anhydride, controlling the reaction temperature to be 62 ℃, stirring at 500r/min for 8h, transferring the reaction solution into a dialysis bag with the cutoff molecular weight of 3000, dialyzing for 3 days by using deionized water, and performing vacuum drying at 0 ℃ to obtain acylated chitosan;

s2, dissolving 5g of acylated chitosan in 80mL of MES buffer solution (0.1M) with the pH value of 6, adding a mixture of 3g of NHS and EDC & HCl (the molar ratio of NHS to EDC & HCl is 1: 1.2), stirring for 50min to obtain a mixed solution, stirring and reacting for 3 days at room temperature in a nitrogen atmosphere, adding 1.5g of DMF solution containing fibroin, neutralizing with 0.1M sodium hydroxide solution, transferring into a dialysis bag with the cutoff molecular weight of 4000-5000, dialyzing for 2 days with deionized water, and freeze-drying to obtain the reinforced modified chitosan.

Example 2:

the reinforced modified chitosan is prepared by the following steps:

s1, dissolving 100g of chitosan in 100mL of acetic acid solution with the mass fraction of 7%, after complete dissolution, adding 100mL of dimethyl sulfoxide for dilution, then adding 20g of succinic anhydride, controlling the reaction temperature to be 62 ℃, stirring at 500r/min for 8h, transferring the reaction solution into a dialysis bag with the cutoff molecular weight of 3000, dialyzing for 3 days by using deionized water, and performing vacuum drying at 0 ℃ to obtain acylated chitosan;

s2, dissolving 5g of acylated chitosan in 50mL of MES buffer solution (0.1M) with the pH value of 6, adding 1.5g of a mixture of NHS and EDC & HCl (the molar ratio of NHS to EDC & HCl is 1: 1), stirring for 30min to obtain a mixed solution, stirring and reacting for 3 days at room temperature under the nitrogen atmosphere and containing 1g of DMF solution added with fibroin, then neutralizing with 0.1M sodium hydroxide solution, transferring into a dialysis bag with the cutoff molecular weight of 5000-6500, dialyzing for 2 days with deionized water, and freeze-drying to obtain the reinforced modified chitosan.

Example 3:

the slow-release perfume particle is prepared by the following method:

a1, taking materials according to the following formula: 0.5g of compound perfume, 20g of enhanced modified chitosan prepared in example 1, 1.5g of sodium dodecyl sulfate, 75g of deionized water and 0.1g of ethanol;

a2, stirring the enhanced modified chitosan, sodium dodecyl sulfate, the compound perfume, ethanol and deionized water at 50 ℃ for 30min to obtain a mixed solution, cooling to room temperature, pouring the mixed solution into a mold, subpackaging, freeze-drying, and demolding to obtain the perfume sustained-release particles.

Example 4:

the slow-release perfume particle is prepared by the following method:

a1, taking materials according to the following formula: 1g of compound perfume, 28g of enhanced modified chitosan prepared in example 2, 2.5g of sodium dodecyl sulfate, 90g of deionized water and 1g of ethanol;

a2, stirring the enhanced modified chitosan, sodium dodecyl sulfate, the compound perfume, ethanol and deionized water at 60 ℃ for 60min to obtain a mixed solution, cooling to room temperature, pouring the mixed solution into a mold, subpackaging, freeze-drying, and demolding to obtain the perfume sustained-release particles.

Example 5:

the slow-release perfume particle is prepared by the following method:

a1, taking materials according to the following formula: 1.5g of compound perfume, 35g of enhanced modified chitosan prepared in example 1, 4g of sodium dodecyl sulfate, 100g of deionized water and 1.5g of ethanol;

a2, stirring the enhanced modified chitosan, sodium dodecyl sulfate, the compound perfume, ethanol and deionized water at 65 ℃ for 40min to obtain a mixed solution, cooling to room temperature, pouring the mixed solution into a mold, subpackaging, freeze-drying, and demolding to obtain the perfume sustained-release particles.

Example 6:

a hair treatment fragrance composition with long lasting fragrance is prepared by the following steps:

step one, weighing the following raw materials by weight: 8g of slow-release perfume particles prepared in example 3, 1.5g of hydroxyethyl cellulose, 1g of stearamidopropyl dimethyl tertiary amine, 0.5g of polygonum multiflorum ethanol extract, 201 g of isocetyl polyether and 75g of deionized water;

and step two, adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring for 20min at the temperature of 40 ℃ at 400-r/min, cooling to room temperature, adding polygonum multiflorum ethanol extract and slow-release perfume particles, and stirring for 50min at 100r/min to obtain the hair treatment perfume composition with lasting fragrance.

Example 7:

a hair treatment fragrance composition with long lasting fragrance is prepared by the following steps:

step one, weighing the following raw materials by weight: 10g of the slow-release perfume particles prepared in example 4, 3g of hydroxyethyl cellulose, 2g of stearamidopropyl dimethyl tertiary amine, 3g of polygonum multiflorum ethanol extract, 202 g of isocetyl polyether and 80g of deionized water;

and step two, adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring for 30min at the temperature of 45 ℃ at the speed of 500r/min, cooling to room temperature, adding polygonum multiflorum ethanol extract and slow-release perfume particles, and stirring for 20min at the speed of 150r/min to obtain the hair treatment perfume composition with lasting fragrance.

Example 8:

a hair treatment fragrance composition with long lasting fragrance is prepared by the following steps:

step one, weighing the following raw materials by weight: 17g of the slow-release perfume particles prepared in example 5, 5.5g of hydroxyethyl cellulose, 3.5g of stearamidopropyl dimethyl tertiary amine, 4.5g of polygonum multiflorum ethanol extract, 203.5 g of isocetyl polyether and 95g of deionized water;

and step two, adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring for 20min at the temperature of 50 ℃ at 700r/min, cooling to room temperature, adding polygonum multiflorum ethanol extract and slow-release perfume particles, and stirring for 30min at the speed of 150r/min to obtain the hair treatment perfume composition with lasting fragrance.

Comparative example 1:

the slow-release perfume particle is prepared by the following method:

a1, taking materials according to the following formula: 0.5g of compound perfume, 20g of acylated chitosan prepared in step S1 of example 1, 1.5g of sodium dodecyl sulfate, 75g of deionized water and 0.1g of ethanol;

a2, stirring acylated chitosan, sodium dodecyl sulfate, compound perfume, ethanol and deionized water at 50 ℃ to obtain a clear solution, cooling to room temperature, pouring the clear solution into a mold, subpackaging, freeze-drying, and demolding to obtain the perfume sustained-release particles.

Comparative example 2:

the slow-release perfume particle is prepared by the following method:

a1, taking materials according to the following formula: 1g of compound perfume, 28g of chitosan, 2.5g of sodium dodecyl sulfate, 90g of deionized water and 1g of ethanol;

a2, stirring chitosan, sodium dodecyl sulfate, compound perfume, ethanol and deionized water at 60 ℃ to obtain a clear solution, cooling to room temperature, pouring the clear solution into a mold, subpackaging, freeze-drying, and demolding to obtain the perfume sustained-release particles.

Comparative example 3:

a hair treatment fragrance composition with long lasting fragrance is prepared by the following steps:

step one, weighing the following raw materials by weight: 8g of perfume slow-release particles prepared in comparative example 1, 1.5g of hydroxyethyl cellulose, 1g of stearamidopropyl dimethyl tertiary amine, 0.5g of polygonum multiflorum ethanol extract, 201 g of isocetyl polyether and 75g of deionized water;

and step two, adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring for 20min at the speed of 40-400 r/min, cooling to room temperature, adding polygonum multiflorum ethanol extract and slow-release perfume particles, and stirring for 50min at the speed of 100r/min to obtain the hair treatment perfume composition with lasting fragrance.

Comparative example 4:

a hair treatment fragrance composition with long lasting fragrance is prepared by the following steps:

step one, weighing the following raw materials by weight: 10g of the slow-release perfume particle prepared in the comparative example 2, 3g of hydroxyethyl cellulose, 2g of stearamidopropyl dimethyl tertiary amine, 3g of polygonum multiflorum ethanol extract, 202 g of isocetyl polyether and 80g of deionized water;

and step two, adding stearamidopropyl dimethyl tertiary amine, isocetyl polyether-20 and hydroxyethyl cellulose into deionized water, stirring for 30min at the temperature of 45 ℃ at the speed of 500r/min, cooling to room temperature, adding polygonum multiflorum ethanol extract and slow-release perfume particles, and stirring for 20min at the speed of 150r/min to obtain the hair treatment perfume composition with lasting fragrance.

Example 9:

firstly, weighing the fragrance compositions obtained in examples 6 to 8 and comparative examples 3 to 4 as weight loss of the air freshener after 7 days in a hot air environment at 40 ℃, and calculating the retention rate (a) of the fragrant substance after 7 days, as shown in table 1;

TABLE 1

	Example 6	Example 7	Example 8	Comparative example 3	Comparative example 4
						a	98.7％	96.5％	97.9％	83.5％	77.9％

As can be seen from the data in table 1, the fragrance-causing substance retention rates (a) of the fragrance compositions obtained in examples 6 to 8 are significantly higher than the fragrance-causing substance retention rates (a) of the fragrance compositions obtained in comparative examples 3 to 4, indicating that the fragrance compositions provided by the present invention have a sustained-release effect on the fragrance;

secondly, the perfume compositions obtained in examples 6-8 and comparative examples 3-4 are used for wig application tests, 25 wigs are selected and divided into 5 groups, the perfume compositions obtained in examples 6-8 and comparative examples 3-4 are applied, No. 6 is a blank group, 10 fragrance testers (5 men and women) smell the fragrance on the wig every 2 hours, the relationship between the fragrance on the wig and the time is tested, 5 wig samples are averaged, the data of 2h, 4h, 8h, 16h, 24h, 36h and 48h are recorded, and the finally obtained data are shown in table 3, wherein the scoring of the fragrance testers is shown in table 2.

TABLE 2

TABLE 3

	Example 6	Example 7	Example 8	Comparative example 3	Comparative example 4
						2h	A	A	A	A	A
4h	A	A	A	A	B
						8h	A	A	A	B	B
16h	B	B	B	C	C
						24h	B	B	B	D	E
36h	B	B	B	E	E
						48h	C	C	C	E	E

From the above data, it can be seen that the perfume compositions obtained in examples 6 to 8 have a longer lasting fragrance than the corresponding performance of the perfume compositions obtained in comparative examples 3 to 4, and that the perfume compositions obtained according to the present invention retain the fragrance of the hair for 36 hours after application to the hair, and that the addition of fibroin plays an important role in lasting fragrance, as can be seen from the data of examples 6 to 8 in combination with the data of comparative examples 3 to 4.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The foregoing is illustrative and explanatory only and is not intended to be exhaustive or to limit the invention to the precise embodiments described, and various modifications, additions, and substitutions may be made by those skilled in the art without departing from the scope of the invention or exceeding the scope of the claims.