阅读说明：本技术 一种逆糖营养代餐食品 (Sugar-free nutritional meal replacement food ) 是由 颜旭文 于 2021-09-13 设计创作，主要内容包括：本发明涉及营养代餐食品技术领域,具体涉及一种逆糖营养代餐食品。一种逆糖营养代餐食品,按重量份计由以下原料混合而成：魔芋粉3-7份、苦瓜粉3-7份、黄豆粉2-6份、燕麦粉1-3份、藜麦粉1-3份和黄精粉0.1-2份。本发明的逆糖营养代餐食品在食用的3-6月后,II型糖尿病病人在不食用任何降血糖药物的情况下空腹血糖控制在7.0mmol/L以内,餐后2h血糖控制在8.0mmol/L以内,具有明显的治疗效果；且食用一段时间后,经检测II型糖尿病病人胰腺β细胞分泌胰岛素的功能都有不同程度的提高,实现了糖尿病病程逆转的愿望。(The invention relates to the technical field of nutritional meal replacement food, in particular to a sugar-inverted nutritional meal replacement food. The invert sugar nutritional meal replacement food is prepared by mixing the following raw materials in parts by weight: 3-7 parts of konjak powder, 3-7 parts of bitter gourd powder, 2-6 parts of soybean powder, 1-3 parts of oat powder, 1-3 parts of quinoa powder and 0.1-2 parts of fine yellow meal. After the food is eaten for 3-6 months, the fasting blood sugar of a type II diabetes patient is controlled within 7.0mmol/L under the condition of not eating any hypoglycemic drug, and the blood sugar of the type II diabetes patient is controlled within 8.0mmol/L after 2 hours of eating, so that the food has an obvious treatment effect; after the food is eaten for a period of time, the functions of pancreas beta cells of patients with type II diabetes to secrete insulin are improved to different degrees through detection, and the desire of reversing the course of diabetes is realized.)

1. The invert sugar nutritional meal replacement food is characterized by being prepared by mixing the following raw materials in parts by weight: 3-7 parts of konjak powder, 3-7 parts of bitter gourd powder, 2-6 parts of soybean powder, 1-3 parts of oat powder, 1-3 parts of quinoa powder and 0.1-2 parts of fine yellow meal.

2. The invert sugar nutritional meal replacement food according to claim 1, which is prepared by mixing the following raw materials in parts by weight: 5 parts of konjaku flour, 5 parts of balsam pear powder, 4.5 parts of soybean flour, 1 part of oat flour, 1 part of quinoa flour and 0.5 part of rhizoma polygonati flour.

3. The retrograded sugar nutritional meal replacement food according to claim 1, wherein the particle sizes of the konjac powder, the soybean powder, the bitter gourd powder, the oat powder, the quinoa powder and the polygonatum powder are all 200-300 meshes.

Technical Field

The invention relates to the technical field of nutritional meal replacement food, in particular to a sugar-inverted nutritional meal replacement food.

Background

Under normal conditions, the food containing carbohydrate is quickly digested and absorbed in human body, and the concentration of sugar in human blood is increased, so that the blood sugar is increased. After the blood sugar rises, pancreatic beta cells of a human body are stimulated to secrete insulin, and then the rising blood sugar is promoted to synthesize glycogen and store the glycogen in liver cells so as to reduce the concentration of sugar in the blood. When the human body consumes energy, the energy is provided by saccharides in blood, and glycogen in liver cells is consumed to supplement blood sugar after the blood sugar is reduced, so that the blood sugar concentration in the human body is maintained within a normal range.

The type II diabetes mellitus patients can continuously increase the blood sugar concentration due to excessive carbohydrate intake from food which exceeds the energy consumption requirement of human bodies, beta cell fatigue and failure caused by continuous stimulation of pancreatic beta cells to secrete insulin, subsequent secretion of insulin is less and less, absolute insulin deficiency is caused, and the blood sugar concentration in human bodies exceeds a normal range, so that the type II diabetes mellitus is formed. Meanwhile, due to excessive glycogen stored in liver cells, glycolysis generates acetone dihydrogen phosphate, glycerol is formed after reduction, and the sugar is oxidized and decomposed to generate acetyl coenzyme A. Acetyl coenzyme A is a raw material for synthesizing fatty acid, glycerin and fatty acid synthesize fat, fat is synthesized in liver cells, and the sugar storage capacity is weakened. The reduced ability of hepatocytes to store glycogen leads to a reduced ability of insulin to promote the conversion of blood glucose to glycogen, resulting in insulin resistance, which in turn exacerbates the onset of type II diabetes.

Therefore, the pathogenesis of type II diabetics is: when too much carbohydrate-containing food is eaten and the energy consumed by the body is relatively small, the concentration of sugar in blood is continuously increased, and beta cells of pancreas are repeatedly stimulated to secrete insulin, so that the function of the beta cells to secrete insulin is fatigued and exhausted. The beta cells secrete less and less insulin, which causes the absolute deficiency of insulin in human bodies, and simultaneously, the glycogen in the liver cells is heterogenized to generate fat, so that insulin resistance is formed. The absolute deficiency of insulin and insulin resistance in the human body are the pathological mechanisms that contribute to type II diabetes, and are also the major causes of type II diabetes.

The current measures for treating type II diabetes mainly comprise the following three types:

oral drug therapy: the action mechanism of the biguanide medicine is to inhibit the generation of hepatic glucose, reduce the absorption of sugar by intestines, improve the sensitivity of insulin by increasing the intake and utilization of peripheral sugar and achieve the effect of reducing blood sugar. The biguanide drugs only reduce the absorption of sugar, have limited ability to reduce blood sugar, cannot recover the tired beta cells well, and can only passively improve the sensitivity of insulin without removing fat in liver cells, so the biguanide drugs have limited ability to resist insulin, and are not suitable for symptomatic treatment. ② sulfonylurea medicine, the action mechanism is to promote the secretion of insulin by combining with sulfonylurea receptor. Because beta cells secreting insulin of type II diabetes patients are stimulated repeatedly and fatigue, if the diabetes patients eat sulfonylureas drugs and then promote the secretion of insulin, the function failure of the beta cells secreting insulin is easily caused. The glycosidase inhibitor can inhibit the absorption of sugar by intestines, has limited ability of reducing blood sugar, and has no treatment to the etiology of type II diabetes. Dipeptidyl peptidase inhibitor and GLP-1 receptor agonist promote the secretion of insulin by inhibiting the secretion of glucagon, and do not treat the etiology of type II diabetes. (v) insulin sensitizer, which does not remove fat from liver cells and has limited effect on insulin resistance. Sixth, SGLT-2 inhibitor, which is to discharge hyperglycemia from kidney, and is not the cause of permanent cure.

Insulin injection treatment: the timely supplement of exogenous insulin for the diabetes mellitus II is an effective symptomatic treatment measure naturally due to the absolute shortage of insulin, but the exogenous insulin has an inhibition effect on the secretion of insulin by beta cells after entering a human body, and the secretion function of the beta cells enters a dormant or abandoned state due to the continuous inhibition along with the continuous entering of the exogenous insulin until the beta cells basically and completely lose the function of secreting the insulin, which is also the reason that the dosage of the insulin is gradually increased along with the time increase after the insulin is injected.

And (3) surgical treatment: the gastrointestine open surgery mechanically reduces the absorption of carbohydrates in food for type II diabetes patients in an operation mode, only treats symptoms and does not treat the root causes. Pancreas transplantation, pancreas function decline and weakness of patients with type II diabetes, pancreas replacement by operation is a natural treatment method, but pancreas transplantation has large risk and high cost, causes of type II diabetes are not eradicated, and type II diabetes is easy to relapse after pancreas replacement, so the operation treatment method has no wide popularization value.

The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person skilled in the art.

Disclosure of Invention

The invention aims to provide a sugar-inversion nutritional meal replacement food to solve the problems of the existing II-type diabetes treatment measures.

In order to achieve the purpose, the invention provides the following technical scheme:

the invert sugar nutritional meal replacement food is prepared by mixing the following raw materials in parts by weight: 3-7 parts of konjak powder, 3-7 parts of bitter gourd powder, 2-6 parts of soybean powder, 1-3 parts of oat powder, 1-3 parts of quinoa powder and 0.1-2 parts of fine yellow meal.

Preferably, the invert sugar nutritional meal replacement food is prepared by mixing the following raw materials in parts by weight: 5 parts of konjaku flour, 5 parts of balsam pear powder, 4.5 parts of soybean flour, 1 part of oat flour, 1 part of quinoa flour and 0.5 part of rhizoma polygonati flour.

Preferably, the particle sizes of the konjac powder, the soybean powder, the bitter gourd powder, the oat powder, the quinoa powder and the sealwort powder are all 200-300 meshes.

The action mechanism of each raw material component of the invention is as follows:

the konjac flour contains a large amount of mannoside, vitamins, dietary fibers and a certain amount of mucin, is a low-heat, low-carbohydrate and high-dietary-fiber food, and has 5 kcal of medium energy per 100g and 2.3g of carbohydrate. Konjak contains the most excellent soluble dietary fiber found at present, and the main effective component of the konjak is glucomannan. The glucomannan can form a protective layer around food, inhibit intestinal absorption of cholesterol and bile acid, prolong food retention time in stomach, and increase satiety. Secondly, glucomannan can form a protective film on the intestinal wall, and mucin contained in konjak can reduce the accumulation of cholesterol in the body, prevent arteriosclerosis and prevent and treat cardiovascular and cerebrovascular diseases.

The soybean powder is comprehensive in nutrition and rich in a large amount of unsaturated fatty acid, multiple trace elements, vitamins and high-quality protein, wherein the contained pancreatic enzyme inhibiting substances have a treatment effect on diabetes; the contained saponin has obvious functions of reducing blood fat and inhibiting the growth of tumor cells; the lecithin contained in the composition can reduce the serum cholesterol and fat content of a human body; the contained sterol substance can effectively increase nerves and promote vitality of nerves; the isoflavone has anticancer and cardiovascular protecting effects. In addition, the soybean powder is low-carbon compound and low-energy food, and each 100g of the soybean powder contains 9.4g of carbohydrate and has energy of 125 kcal.

The balsam pear is rich in nutrition, contains rich nutrients such as vitamins, amino acids, pectin, protein, cellulose and the like, and can provide various nutrients for a human body; simultaneously contains charantin and substances similar to insulin, has good effect of reducing blood sugar, and is an ideal food for diabetic patients. In addition, the bitter gourd powder per 100g has only 9 kcal of energy and 0.8g of carbohydrate, is a low-energy and low-carbohydrate food, and is very suitable for patients with type II diabetes to eat.

The oat flour is rich in protein and vitamin B₂Vitamin E, and nutrients such as nicotinic acid, folic acid and dietary fiber, especially the contained dietary fiber can reduce low-density fatty protein of triglyceride, delay the absorption of carbohydrate and inhibit the increase of blood sugar concentration after meals; meanwhile, the oat fiber in the oat can absorb water and swell in intestines and stomach to form high-viscosity sol or gel, so that the emptying time of the intestines and stomach is delayed, and satiety is easily generated.

The quinoa wheat flour is rich in magnesium, manganese and other mineral substances, and can reduce blood sugar in vivo; the health-care food also contains natural phytoestrogen which is not a hormone, is mainly an isoflavone active ingredient and is commonly used for reducing blood pressure, blood sugar and blood fat clinically; in addition, the health-care food also contains relatively abundant dietary cellulose which is an excellent source of soluble and insoluble cellulose, and the two celluloses have good effects of regulating blood sugar level, reducing cholesterol and protecting heart. The quinoa wheat flour is added in the invention, firstly, the quinoa wheat flour has the function of reducing blood sugar; secondly, the amino acid is rich in various amino acids, so that the amino acid is easy to absorb in proper proportion. The quinoa flour contains abundant amino acids, can participate in synthesizing human proteins such as immune antibody, digestive enzyme, plasma protein and growth hormone, and can improve intelligence, promote growth, enhance body constitution, improve malnutrition, improve sleep, etc.; thirdly, the quinoa wheat flour is an alkaline food, more big fish meat is eaten or the energy is supplied by fat, ketone bodies can be generated, the physique is in a sub-healthy state easily caused by acid, and the quinoa wheat flour can play a role in improving the acid-base balance in the body and keeping the healthy physique after being eaten.

Rhizoma Polygonati polysaccharide, which is effective component of rhizoma Polygonati powder, has effects of lowering blood sugar and saccharifying hemoglobin; in addition, substances contained in the sealwort have obvious inhibition effect on hyperglycemia caused by adrenalin. Rhizoma Polygonati has antioxidation effect after entering human body, and can improve the activity of superoxide dismutase in liver, so that the skin of eaters is better and better; secondly, the sealwort has the effects of tonifying qi and nourishing yin, and has certain benefits for the kidney after being eaten for a long time; in the invention, the rhizoma polygonati powder is added, so that part of components in the rhizoma polygonati have the function of reducing blood sugar; secondly, rhizome of rhizoma polygonati contains rhizoma polygonati polysaccharide, rhizoma polygonati oligosaccharide, quinones, mucilage, amino acid, zinc, copper, iron and other trace elements necessary for human body; thirdly, diabetes belongs to the category of diabetes in traditional Chinese medicine, the key point for treating diabetes is to nourish yin and tonify the kidney, invigorate the spleen and replenish qi, and the sealwort powder has the efficacy of nourishing yin and tonifying the kidney.

In the raw material components, the glucomannan in the konjac flour can prolong the retention time of food in the stomach and increase satiety; it is combined with Ku ya powder to enhance the action of lowering blood sugar, so it is the monarch drug. The soybean powder contains more vegetable protein and has excellent quality, can ensure nutrient substances required by human life activities, and is a minister. The quinoa wheat powder and the oat powder are used as adjuvants to inhibit the increase of blood sugar concentration after meals and improve acid-base balance in vivo, so as to maintain healthy constitution, and can enhance the efficacy of invert sugar by being combined with monarch and minister drugs. The sealwort powder has the functions of nourishing yin and tonifying kidney and is used for introducing kidney channels, so that various raw materials are scientifically matched, and the sealwort powder has an obvious treatment effect on the type II diabetes.

Compared with the prior art, the invention has the following beneficial effects:

(1) the food for replacing meal with invert sugar nutrition of the invention is based on the premise that the beta cells of the pancreatic islets of Langerhans of type II diabetics do not completely lose the function of secreting insulin, and after 3-6 months of insisting on eating the food for replacing meal with invert sugar nutrition of the invention, the fasting blood sugar of the type II diabetics is controlled within 7.0mmol/L under the condition of not eating any hypoglycemic drugs, and the blood sugar of the type II diabetics is controlled within 8.0mmol/L after 2 hours of eating, thus having obvious treatment effect.

(2) After the sugar-inversion nutritional meal replacement food is eaten for a period of time, the functions of pancreatic beta cells of a patient with type II diabetes to secrete insulin are improved to different degrees through detection, and the desire of reversing the course of diabetes is fulfilled.

Detailed Description

In the following, the technical solutions of the present invention will be described clearly and completely, and it is obvious that the described embodiments are some, not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A sugar-inversion nutritional meal replacement food is prepared by mixing the following raw materials: 3g of konjak powder, 3g of bitter gourd powder, 2.75g of soybean powder, 1g of oat powder, 1g of quinoa powder and 0.25g of rhizoma polygonati powder; the particle sizes of the konjac powder, the soybean powder, the bitter gourd powder, the oat powder, the quinoa powder and the sealwort powder are all 200 meshes.

Example 2

A sugar-inversion nutritional meal replacement food is prepared by mixing the following raw materials: 5g of konjak powder, 5g of bitter gourd powder, 4.5g of soybean powder, 1g of oat powder, 1g of quinoa powder and 0.5g of rhizoma polygonati powder; the particle sizes of the konjac flour, the soybean flour, the bitter gourd powder, the oat powder, the quinoa flour and the fine yellow meal are all 250 meshes.

Example 3

A sugar-inversion nutritional meal replacement food is prepared by mixing the following raw materials: 7g of konjac powder, 7g of bitter gourd powder, 6g of soybean powder, 3g of oat powder, 3g of quinoa powder and 2g of fine yellow powder; the particle sizes of the konjac powder, the soybean powder, the bitter gourd powder, the oat powder, the quinoa powder and the sealwort powder are all 300 meshes.

Eating investigation

1. Selecting a patient suffering from type II diabetes mellitus and whose islet beta cells have not completely lost insulin-secreting function;

2. the sugar-free nutritional meal replacement food in the embodiment 2 of the invention is continuously eaten for 100g each day: wherein 20g of breakfast, 40g of Chinese meal and dinner respectively are taken with 300-400mL of boiled water.

The blood glucose control levels of people eating the present retrograded nutritional meal replacement food 187 are detailed in table 1, following the above-described method.

TABLE 1 summary of glycemic control levels in 187 type II diabetics after eating the present invert sugar nutritional meal replacer

As can be seen from Table 1, the fasting blood glucose is maintained below 7 mmol/m and the blood glucose is maintained below 8 mmol/m after 2h of meal during the period of 3-6 months when 187 people eat the invert sugar nutritional meal replacement food of the invention, and all the blood glucose reaches the blood glucose reduction target. Therefore, the invert sugar nutritional meal replacement food can effectively reduce the blood sugar of the patients with type II diabetes.

The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. It is not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain certain principles of the invention and its practical application to enable one skilled in the art to make and use various exemplary embodiments of the invention and various alternatives and modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims and their equivalents.