阅读说明：本技术 用于跟踪产品的方法和将粉末状产品加工成成品的设备 (Method for tracking products and device for processing powdered products into finished products ) 是由 N·沃尔特 A·埃弗斯 于 2021-06-11 设计创作，主要内容包括：本发明涉及一种用于在设备中跟踪产品的方法,在设备中将粉末状产品加工成成品,其中,根据至少一个布置在设备的产品入口处的入口质量传感器的测量数据将输入到设备中的产品划分成质量单元,并且其中,根据设备的至少一个另外的质量传感器的测量数据跟踪质量单元在设备中的行进。此外,本发明还涉及一种用于将粉末状产品加工成成品的设备。(The invention relates to a method for tracking products in a system, in which a product in powder form is processed to form a finished product, wherein the product introduced into the system is divided into mass units as a function of measurement data of at least one inlet mass sensor arranged at the product inlet of the system, and wherein the travel of the mass units in the system is tracked as a function of measurement data of at least one further mass sensor of the system. The invention also relates to a device for processing a powdery product into a finished product.)

1. A method for tracking products in a plant in which powdered products are processed into finished products, characterized in that the product input into the plant is divided into mass units (64, 66, 68, 70) on the basis of measurement data of at least one inlet mass sensor arranged at a product inlet (52, 54) of the plant, and the travel of the mass units (64, 66, 68, 70) in the plant is tracked on the basis of measurement data of at least one further mass sensor of the plant.

2. The method of claim 1, wherein the travel of the quality units (64, 66, 68, 70) in the device is tracked in real time.

3. Method according to any of the preceding claims, characterized in that the apparatus is an apparatus for manufacturing tablets, in which apparatus a powdery product is compressed into tablets in a tablet press.

4. A method as claimed in claim 3, characterized by tracking the travel of the mass unit (64, 66, 68, 70) in the apparatus on the basis of the measurement data of a further mass sensor arranged at the tablet outlet of the tablet press (62).

5. A method as claimed in any one of claims 3 or 4, characterized in that the travel of the mass units (64, 66, 68, 70) in the apparatus is tracked on the basis of the measurement data of further mass sensors arranged at the filling device (26) of the tablet press (62).

6. Method according to any one of the preceding claims, wherein the apparatus is an apparatus for manufacturing capsules in which a capsule is filled with a powdered product in a capsule filling machine.

7. Method according to any of the preceding claims, characterized in that the apparatus comprises a plurality of product inlets (52, 54) for different powdered products and a mixing device (56) for mixing the different products before processing into finished products, wherein the product input into the apparatus is divided into mass units (64, 66, 68, 70) on the basis of measurement data of a plurality of inlet mass sensors arranged at the product inlets of the apparatus.

8. The method as claimed in claim 7, characterized in that the travel of the mass unit (64, 66, 68, 70) in the apparatus is tracked on the basis of the measurement data of at least one further mass sensor arranged at the mixing device (56).

9. Method according to any of claims 7 or 8, characterized in that for tracking the progress of the mass units (64, 66, 68, 70) in the apparatus, the mixing of different mass units (64, 66, 68, 70) into a new mass unit (64, 66, 68, 70) in the mixing device (56) is taken into account.

10. Method according to claim 9, characterized in that for taking into account the mixing of different mass units (64, 66, 68, 70) in the mixing device (56) into a new mass unit (64, 66, 68, 70), the mixing ratio achieved by the mixing device (56) is taken into account.

11. Method according to any of claims 9 or 10, characterized in that in order to take into account that different mass units (64, 66, 68, 70) are mixed in the mixing device (56) into a new mass unit (64, 66, 68, 70), a moving average is taken from the successive mass units.

12. Method according to any of the preceding claims, characterized in that for tracking the progress of the quality units (64, 66, 68, 70) in the apparatus backmixing of different quality units (64, 66, 68, 70) is taken into account.

13. The method of claim 12, wherein the back-mixing caused by the equipment is determined empirically.

14. Method according to any of the preceding claims, characterized in that for tracking the travel of the quality units (64, 66, 68, 70) in the plant dead zones for the product in the plant are taken into account.

15. Method according to any of the preceding claims, characterized in that for tracking the travel of the quality units (64, 66, 68, 70) in the apparatus product losses in the apparatus, in particular product losses generated by the suction means of the apparatus, are taken into account.

16. The method of claim 15, wherein the product loss is determined by comparing the mass flow into the apparatus and the number and weight of finished products exiting the apparatus for a predetermined amount of product.

17. The method according to any of the preceding claims, wherein the mass of each mass unit (64, 66, 68, 70) is the same.

18. The method according to any of the preceding claims, wherein the mass of each mass unit (64, 66, 68, 70) is in the range of 1g to 20g, preferably in the range of 1g to 10 g.

19. Method according to any of the preceding claims, characterized in that a plausibility assessment of the tracking of the travel of the quality unit (64, 66, 68, 70) in a device is made from the measurement data of a plurality of measurement sensors of the device.

20. Method according to any of the preceding claims, wherein the at least one product inlet (52, 54) comprises at least one metering conveyor, in particular a loss-of-weight metering conveyor.

21. Method according to any one of the preceding claims, characterized in that the apparatus is an apparatus for continuously processing a powdery product into finished products.

22. A method according to any preceding claim, wherein the apparatus is a closed apparatus.

23. A device for processing a powdery product into a finished product, characterized in that the device has at least one inlet mass sensor at a product inlet (52, 54) of the device, the product fed into the device being divisible into mass units (64, 66, 68, 70) as a function of measurement data of the at least one inlet mass sensor, and at least one further mass sensor, the travel of which mass units (64, 66, 68, 70) in the device being trackable as a function of measurement data of the at least one further mass sensor.

Technical Field

The invention relates to a method for tracking products in a system, in which a powdery product is processed into a finished product.

Background

In such devices, for example, powdered products are processed into tablets or capsules. Accordingly, the apparatus may comprise, for example, a tablet press or a capsule filling machine. Such a device has one or more product inlets for the powdered product to be processed in the device. If a plurality of product inlets are provided for different products, this type of plant also usually has a mixing device in which the products are mixed to the product to be pressed. The mixed product is then fed from the mixing device, for example, to a tablet press, for example a rotary tablet press, where the product mixture is compressed into tablets. The finished tablets exit the apparatus through the tablet outlet of the tablet press. Such a device can be configured as a continuous device, in which the product continuously fed to the device, for example into tablets or capsules, is continuously processed, as opposed to batch processing. Furthermore, so-called closed systems are known which prevent product dust from leaving into the environment as far as possible by special sealing measures.

In particular, in continuously operating installations, there is a need to match the product fed into the installation at the inlet to the finished product produced in the installation. This is required when a product is identified as defective, for example by a sensor of the device. In this case, the finished products made of the product, for example tablets or capsules, must be sorted out, wherein, in order to avoid unnecessary waste, as far as possible only the finished products made of the respective product batch are sorted out. Accordingly, there is a need to track products in a facility.

In order to track the product, so-called dwell time models are known in which the finished product produced is matched to the product fed into the installation according to the dwell time or transit time of the product through the installation. However, product tracking based on such residence time models is complicated, especially when delivering a number of different products into the plant. That is, the residence time may vary depending on the product being delivered. Accordingly, the residence time must be redetermined for each product combination to obtain reliable results. Furthermore, the accuracy of the residence time model is largely dependent on the operating point of the plant, i.e. the operating parameters adjusted accordingly. This can of course be seen directly for the production speed of the device. However, the residence time is also dependent on other operating parameters, such as the mode of operation of the mixing device. Very small deviations from the operating point must already be taken into account in the dwell time model. It must be determined again empirically, in particular also from the respective product, how this deviation from the operating point contributes to the dwell time. Therefore, the cost of parameterizing the residence time model to achieve acceptable accuracy is very high.

Disclosure of Invention

Starting from the explained prior art, the object of the invention is to provide a method of the type mentioned at the outset, with which product tracking in a plant, in which a powdered product is processed to a finished product, is achieved in a simple and precise manner.

The invention achieves this object by the subject matter of claim 1. Advantageous embodiments are found in the dependent claims, the description and the drawings.

With a method of the type mentioned at the outset, the invention achieves this object by dividing the product fed into the device into mass units on the basis of measurement data of at least one inlet mass sensor arranged at the product inlet of the device and by tracking the travel of the mass units in the device on the basis of measurement data of at least one further mass sensor of the device (fortging).

The apparatus comprises one or more product inlets for products to be processed in the apparatus. Furthermore, the apparatus may comprise mixing means for mixing the different products delivered to the apparatus. The apparatus furthermore comprises a production machine, for example a tablet press, for example a rotary tablet press, or a capsule filling machine, in which the product fed to the apparatus or the product mixture produced in the mixing device is processed to form finished products, for example tablets or capsules. For example, the final product is Oral Solid preparation (Oral Solid solutions OSD). The apparatus has an inlet quality sensor disposed at the product inlet that determines the weight or mass of the product being delivered to the apparatus. For example, in an evaluation and control device of the installation, the division of the product fed to the installation into successive quality units is determined as a function of this quality. The device has at least one further mass sensor which is arranged downstream of the at least one inlet mass sensor in the flow direction of the product and which determines the mass or weight of the product flowing through the device. Hereby, the travel of the quality unit in the device is tracked. The product tracking is preferably carried out by means of an evaluation device of the apparatus, preferably according to an evaluation algorithm. In this case, the mass sensor can measure the mass directly, i.e. including the weighing device, or the mass flow directly. However, the mass sensor may also measure mass or mass flow indirectly.

Thus, in contrast to the prior art, the present invention proposes product tracking that is not time-based, but rather quality-based. The mass units or units of mass are small enough for ensuring a sufficient product tracking accuracy for the respective purpose of use. For example, the mass unit may have a size of less than 50 g. In particular, fluctuations in the flow rate or production rate of (in) the apparatus have a frequency which is less than the frequency of the successive mass elements. The product tracking is thus substantially independent of fluctuations in the flow or production rate and therefore of corresponding deviations from the determined operating point of the installation. In this way, product tracking is achieved reliably and with minimal scrap when defective product batches are identified, for example, the quality units at the outlet of the tablet press or capsule filling machine or device are detected and, on the basis thereof, matched to the product or product batch fed to the device.

In the evaluation unit, the mass element is moved through the device similarly to the shift register model. It has been shown that in the product tracking according to the invention, the mass reference (massebezu) already implicitly has the property of being achievable in a time-based model (residence time model) only by using higher-order equations in the corresponding evaluation algorithm. The number of parameters required for adaptation to the determined operating point of the product or installation is thereby significantly reduced in comparison with conventional residence time models. At the same time, it is achieved according to the invention that material properties are also observed which are independent of the concentration or residence time in the plant components. This is obtained from the basic structure of the product tracking according to the invention, similarly to the shift register for the final quality unit. In the extreme case, it is therefore possible to mark a single quality unit as defective or for sampling and to remove it from the device at a later time.

According to a preferred embodiment, the travel of the mass unit in the device can be tracked in real time. In this way, a comparison of the product tracking model, in particular the corresponding algorithm, with the other sensor parameters of the device is achieved. Therefore, the robustness and the durability of the product tracking model can be further improved.

As mentioned, the apparatus may be an apparatus for manufacturing tablets, in which apparatus a powdered product is compressed into tablets in a tablet press. Thus, the apparatus may comprise a tablet press, such as a rotary tablet press.

According to a further embodiment, the travel of the mass unit in the device is tracked on the basis of the measurement data of a further mass sensor arranged at the tablet outlet of the tablet press. The further mass sensor may be, for example, a sensor with which the number of tablets output from the tablet press is counted. For a predetermined process, the weight of the tablet can be assumed to be known. Thus, by tablet counting, an indirect weight or mass determination can be made. However, it is of course also possible for the additional mass sensor to count and weigh the output tablets. In the above-described embodiment, the finished tablets are directly matched to the respective mass unit at the inlet and thus to the respective product batch.

According to a further embodiment, the travel of the mass unit in the device is tracked on the basis of the measurement data of further mass sensors arranged on the filling device of the tablet press. The mass sensor may again measure mass or mass flow, either directly or indirectly. The filling device of a tablet press usually has a filling tube, through which the powdered product is fed to a filling chamber, from which the filled powdered product is filled into the cavities of the die plate of the press, where it is subsequently pressed by the upper and lower punches of the tablet press. A filling reservoir may be arranged upstream of the filling pipe. The further mass sensor can be arranged, for example, at the filling tube, the filling reservoir or the filling chamber.

The device may also be a device for manufacturing capsules, in which a capsule is filled with a powdered product in a capsule filling machine. The apparatus may then accordingly comprise a tablet filling machine.

The travel of the mass unit in the device can then be tracked, for example, on the basis of the measurement data of a further mass sensor arranged at the outlet of the capsule filling machine. For example, the further quality sensor may be a sensor for counting the number of capsules output from the capsule filling machine. For a predetermined procedure, the weight of the capsule may be assumed to be known. Thus, an indirect weight or mass determination can be made again by counting the capsules. However, it is of course also possible for the further mass sensor to count and weigh the outgoing capsules.

According to a further embodiment, the device comprises a plurality of product inlets for different powdered products and a mixing device for mixing the different products before processing into a finished product, for example before compression into tablets in a tablet press or before filling capsules in a capsule filling machine, wherein the product fed into the device is divided into mass units as a function of the measurement data of a plurality of inlet mass sensors arranged at the product inlets of the device.

The travel of the mass unit in the device can then be tracked on the basis of the measurement data of at least one further mass sensor arranged on the mixing device. For example, the different products delivered to the device may be a pharmaceutically Active Ingredient (Active Pharmaceutical Ingredient API), an excipient (exipient) and/or a lubricant. The different products are fed to the apparatus through separate inlets, from which they are fed to a mixing apparatus, where they are mixed into a product mixture to be pressed. For example, the mixing device may comprise a mixing zone. Thereby, the products are simultaneously delivered while mixing.

According to a further embodiment, for tracking the progression of the mass units in the system, the mixing of different mass units into a new mass unit in the mixing device is considered. To take this mixing into account, the mixing ratio achieved by the mixing device can be taken into account. That is, a new mass unit containing the mixed product is formed from the mass units present in the mixing device. The mixing ratio of the mixing device is thereby dependent on the specifications of the mixing device and, if appropriate, the delivery rate of the individual products. Thus, for the respective processes, the mixing ratio is known and can be used to take into account the mixing. If the mixing device mixes, for example, two products identically in a ratio of 50% to 50%, the new mass units contain half the first product and half the second product, respectively. Accordingly, the new mass units are divided differently with the other mixing ratios achieved by the mixing device. In the mixing device, the mass units are mixed with one another according to a known mixing ratio. This can be taken into account, for example, by moving averaging successive mass units and forming a new mass unit from the correspondingly calculated average. In this way it can be calculated to what extent a certain mass unit has a component of a different product batch from a different product inlet.

In addition to the mixing device, the mixing or dispersion can also be carried out in other components of the apparatus in which the stirrer mixes the product batch, or, for example, in the filling device of the tablet press. For tracking the progression of the mass units in the apparatus, it is accordingly also conceivable for different mass units to be mixed in other components of the apparatus, for example in a metering conveyor or in a tablet press or in a capsule filling machine, to form new mass units. To take account of this mixing, the mixing ratios achieved by the respective components can again be taken into account. New mass units are formed again from the mass units arriving in the respective assemblies, which mass units contain the mixed product. The mixing ratios of the components are generally known for the respective process and can be used to take account of the mixing, which has already been explained for example for mixing devices.

According to a further embodiment, backmixing of different mass units can be taken into account in order to track the progression of the mass units in the plant. This back-mixing, in which the product is exchanged between different quality units, e.g. from one quality unit into a previous quality unit, may be intentional or unintentional. In any case, the back-mixing is usually specific to the respective plant. Thus, the backmixing can be empirically determined in advance and then considered in the algorithm for product tracking. For example, to empirically determine this back-mixing, experiments based on spectral analysis may be performed. It is also conceivable to use so-called tracers which can be explicitly back-tracked, for example due to a defined coloration.

According to a further embodiment, dead zones for the products in the system can also be taken into account for the tracking of the travel of the mass unit. Products that may later exit the apparatus may accumulate in dead or blind areas of this type. Such dead zones occur, for example, in screw conveyors for the further conveyance of products in plants. Such dead zones may again be obtained empirically, since they are likewise generally specific to the respective device and are subsequently taken into account in the algorithm for product tracking.

According to a further embodiment, product losses in the device, for example by means of the suction device of the device, can be taken into account in order to track the travel of the mass unit in the device. Especially in the case of long operating times of the plant, such product losses are significant and have to be compensated by more material replenishment. In the time-based residence time model, the parameters of the model have to be changed in a complex manner for this purpose. According to the invention, this is not required. The product loss can be determined by comparing the mass flow into and out of the apparatus, for example the number and weight of finished product exiting the apparatus (e.g. tablet or capsule filling machine) per unit time, for a predetermined amount of product. When the product is also slightly evacuated in addition to air, product losses can occur when, for example, the tablet press is evacuated, as is usual for maintaining a negative pressure in the tablet press. This product loss is usually again specific to the respective plant and can accordingly be determined empirically, for example in the manner explained above.

According to a preferred embodiment, the mass of the mass elements can be identical. This simplifies the back tracking, especially the algorithm for product tracking, if all quality units have the same quality.

As explained at the outset, the mass unit has a sufficiently small mass for reliable and accurate product tracking. According to a design related thereto, the mass of the mass unit can be in the range from 1g to 20g, preferably in the range from 1g to 10 g. In particular, all mass units can have the same mass, so that the same mass is a mass in the range for all mass units. The quality units are therefore sufficiently small for accurate product tracking and, if necessary, for the purposeful sorting out of the finished product of defective quality units while avoiding a greater number of rejects.

According to a further embodiment, the plausibility assessment of the tracking of the travel of the quality unit in the device can be carried out on the basis of measurement data of a plurality of measurement sensors of the device. When evaluating a plurality of measuring devices for determining the quality of a quality unit, a defective quality determination may be identified, for example when a drift is found when tracking the quality unit.

The at least one product inlet of the apparatus may comprise at least one metering conveyor, in particular a loss of weight metering conveyor. Metering conveyors of this type are used for metered conveying of products. So-called loss-of-weight metering conveyors (LIW-feeders) have weighing devices and meter the product to be conveyed by measuring the weight of the product located in the metering conveyor. In a particularly practical manner, a weighing device can be used as an inlet mass sensor.

As already explained, the invention is particularly suitable for use in a device for continuously processing a powdered product into a finished product, for example for continuous tablet production or capsule filling. As is known, in plants for continuous production, in contrast to batch processes, the product is continuously fed into the plant and continuously processed in the plant to form the finished product, if necessary after the product has been continuously mixed beforehand. Such a device can theoretically be operated continuously, wherein only an adequate product replenishment at the product inlet has to be ensured. Such an apparatus has a number of advantages known to those skilled in the art over batch apparatus. Precisely in such a device for continuous production, for example, the precise and high-resolution product tracking ensured according to the invention is important.

Furthermore, the apparatus can be a so-called Containment-inlage apparatus, which substantially prevents product dust from leaving the apparatus due to special sealing measures. For example, according toThe so-called SMEPAC test (standardized measurement of the air concentration of particles in the equipment) results in a tightness rating of the equipment. For example, the device used in the method according to the invention may have a particle size of 10-100 μ g/m according to the SMEPAC test³Or less than 10 mu g/m³The sealing grade of (2).

Drawings

Embodiments of the present invention are explained in detail below with reference to the drawings.

In which are schematically shown:

fig. 1 shows, in a developed view of a rotor, an apparatus for producing tablets with a tablet press for use in the method according to the invention, and

fig. 2 shows a diagram for explaining the method according to the invention.

Detailed Description

Like reference numerals in the drawings denote like objects, if not otherwise specified.

The apparatus shown in fig. 1 is an apparatus for producing tablets, in which a powdery product is compressed into tablets. Accordingly, the apparatus comprises a rotary press, in particular a rotary tablet press, arranged in a housing 11, with a rotor driven in rotation by a rotary drive, the rotor having a die disc 10 with a plurality of receptacles 12. The receptacle 12 can be formed, for example, by a bore of the die plate 10. Furthermore, the rotor comprises a plurality of upper punches 14 and lower punches 16 which are synchronously surrounded with the die disc 10. The upper punch 14 is guided axially in an upper punch guide 18 and the lower punch 16 is guided axially in a lower punch guide 20. The axial movement of the upper and lower punches 14, 16 during rotation of the rotor is controlled by upper and lower control curve elements 22, 24. The rotary press furthermore comprises a filling device 26 with a filling reservoir 28 and a filling chamber 30 which are connected by a filling tube 32. In this way, in this example, the powdered filling material passes from the filling reservoir 28 through the filling tube 32 into the filling chamber 30 by gravity and from there through the filling opening provided on the underside of the filling chamber 30 again into the receptacle 12 of the cavity plate 10 by gravity.

Furthermore, the rotary press comprises a pressure device 34. The press device 34 comprises a prepressing device with an upper prepress roll 36 and a lower prepress roll 38, and a main press device with an upper main press roll 40 and a lower main press roll 42. Furthermore, the rotary press comprises a discharge device 44 and a discharge device 46 with a discharge element which conveys the tablets 48 produced in the rotary press to an output device 50 for discharge from the rotary press. The discharge device 46 can comprise, for example, a preferably sickle-shaped discharge element which discharges the tablets 48, which are conveyed by the lower punch 16 onto the upper side of the die plate 10, from the die plate 10 in the region of the discharge device 44 and to a discharge device 50.

The housing 11 is under overpressure or underpressure relative to the surroundings of the housing 11. Furthermore, the housing 11 is sealed off from the environment. The rotary press may be a so-called closed press.

It should be clear that the rotary press shown in fig. 1 with its explained properties is merely exemplary. In principle any other type of tablet press is also suitable for the present invention. For the purposes of the present invention, in principle any other type of production machine for processing a powdered product into a finished product is also suitable, for example a capsule filling machine, in which the powdered product is filled into capsules.

Furthermore, in the example shown, the apparatus comprises two product inlets 52, 54 for two different products to be delivered to a tablet press for compressing into tablets 48, for example a pharmaceutically active ingredient on the one hand and an excipient on the other hand. The product inlets 52, 54 may, for example, comprise metering conveyors, in particular loss-of-weight metering conveyors. From the product inlets 52, 54, the conveyed product reaches the mixing device 56 of the apparatus, where the product is mixed into a product mixture to be pressed. For example, the mixing device may comprise a mixing worm. The mixed product leaving the mixing device 56 is conveyed to the filling reservoir 28 of the filling device 26 via a conveying line 58. The device furthermore comprises an evaluation and control device 60 for controlling the operation of the device and for performing the product tracking according to the invention on the basis of an evaluation algorithm stored in the evaluation and control device 60. The product inlets 52, 54, the mixing device 56, the filling device 26, the tablet outlet of the tablet press, in particular of the tablet press, can each comprise at least one mass sensor, by means of which the mass or weight of the product guided through the apparatus, in particular of the tablets output from the apparatus, can be determined directly or indirectly. The evaluation and control device 60 is connected to the quality sensor and, if necessary, to other sensors of the system. In particular, the device receives measurement data of the sensors and uses the measurement data for the basis of control and evaluation. For this purpose, the evaluation and control device 60 is connected to all components of the installation via corresponding connecting lines.

According to fig. 2, the method according to the invention for tracking products in the apparatus shown in fig. 1 is explained in detail. The product inlets 52, 54, the mixing device 56 and the tablet press indicated with reference numeral 62 are shown highly schematically here. The products which are fed into the apparatus via the product inlets 52, 54 are divided into equally large mass units 64, 66 on the basis of the measurement data of the inlet mass sensors arranged on the product inlets 52, 54. In this case, the mass elements 64, 66 of the first product batch are denoted by the numeral 01 and the mass elements 64, 66 of the second product batch are denoted by the numeral 10. At the beginning of the dispersion zone formed by the mixing device 56, a new mass unit 68 is formed from the mass units 64, 66 of the two product inlets 52, 54, in which new mass unit the product portions from the respective two mass units 64, 66 of the two product inlets 52, 54 are included in the mixing device 56 corresponding to the known delivery ratio. In fig. 2, it is assumed, for example, that the conveying ratio is the same for both product inlets 52, 54. For example, in fig. 2, the lowermost mass elements 64, 66 are arranged in the chain of mass elements below the product inlets 52, 54, which means that two new mass elements 68 are formed from these two mass elements 64, 66, which are each formed by the initial mass elements 64, 66 in half. Corresponding to its composition, in numbersRepresenting the mass element 68 so formed. I.e. half of their mass comes from the firstThe first product batch 01 of products from product inlet 52 and half consists of the second product batch 10 of products from second product inlet 54.

In accordance with the mixing ratios of the mixing device 56, which are also known, for example, determined empirically, the mixing of the components of the mass unit in the dispersion zone formed by the mixing device 56 is taken into account until the mass unit, which can be seen in fig. 2 at reference numeral 70, is reached. In this case, the successive mass elements 68 are also mixed with one another in the dispersion zone. Thus, mixing of products from different initial product batches at the product inlets 52, 54 may also occur. Mathematically, the mixing in the dispersion zone is described as a shift register, for example, by a moving average formed from successive mass elements 68. The proportions of the constituent parts of the mass unit 68 given by the digital doublet are thus varied. At the end of the dispersion zone, in the example shown, by a numberRepresenting the formed mass unit 70. This means that in the example shown, the mass unit 70 has 40% of the mass of the second product batch (10) from the first product inlet 52 and 60% of the mass of the first product batch (01) from the first product inlet 52. Furthermore, this means that the mass unit 70 has 60% of the mass of the second product batch (10) from the second product inlet 54 and 40% of the mass of the first product batch (01) of the second product inlet 52. It will be appreciated that the ratio will vary depending on how much of the different batches of product are in the mixing device 56.

The tracking of the mass unit 70 is continued during the travel of the mass unit 70 through the device, in particular to the tablet press 62, in particular on the basis of measurement data of mass sensors, for example, arranged in the filling device 26 of the tablet press. By means of a further mass sensor, which is arranged, for example, at the outlet of the tablet press and counts the number of tablets discharged and, if appropriate, additionally measures the weight of the tablets, the discharged tablets 48 can be matched to a determined mass unit 64, 66 previously fed into the apparatus via the product inlet 52, 54 and thus to the respective product batch of this mass unit 64, 66. In this way, it is achieved that tablets produced from one or more mass units are reliably identified, so that they can be picked out of the produced tablets, if one or more mass units are identified as defective by a sensor of the device, for example during the travel of the mass units through the device.

In tracking the travel of the quality units in the plant, backmixing of the product between different quality units, which is generally specific to the plant, can also be taken into account. The same applies to dead zones for the product, which are generally specific to the plant, or product losses in the plant, which are again generally specific to the plant.

It will be understood that the above-explained division of the product into quality units and the tracking of the respective quality units in the apparatus and the matching of the finished tablets to the determined quality units are carried out by the evaluation and control device 60 on the basis of corresponding models stored in the form of algorithms.

The mass elements 64, 66, 68, 70 may all have the same mass. Preferably, the mass of the mass unit may be less than 20g, more preferably less than 10g, for example about 1 g. The apparatus is particularly an apparatus for the continuous production of tablets. The apparatus may be a closed apparatus.

List of reference numerals

10 concave die plate

11 casing

12 accommodating part

14 upper punch

16 lower punch

18 upper punch guide

20 lower punch guide

22 upper control curve element

24 lower control curve element

26 filling device

28 fill reservoir

30 filling cavity

32 fill tube

34 pressure device

36 upper prepressing roll

38 lower prepressing roll

40 upper main press roll

42 lower main press roll

44 discharge device

46 discharge device

48 tablets

50 output device

52 product inlet

54 product inlet

56 mixing device

58 conveying pipeline

60 evaluation and control device

62 tablet press

64 mass unit

66 mass units

68 mass unit

70 mass unit