Wearable sweat sensor device for real-time continuous detection of electrolyte concentration

文档序号:240136 发布日期:2021-11-12 浏览:8次 中文

阅读说明:本技术 一种实时连续检测电解质浓度的可穿戴汗液传感器装置 (Wearable sweat sensor device for real-time continuous detection of electrolyte concentration ) 是由 张珽 刘梦愿 王书琪 杨显青 冯思佳 吴越 于 2021-09-01 设计创作,主要内容包括:本发明公开了一种实时连续检测电解质浓度的可穿戴汗液传感器装置。所述传感器装置包括:汗液通道,其一端开口靠近皮肤表面设置,用于使皮肤表面所产生的汗液连续输入;检测机构,其用于对流经汗液通道的汗液进行检测,以获取所述汗液中的电解质浓度信息;吸汗机构,其与所述汗液通道远离皮肤的另一端开口配合,用于持续吸取所述汗液通道输出的汗液,以使皮肤表面所产生的汗液连续通过所述汗液通道。本发明的可穿戴汗液传感器装置可实时连续地检测汗液电解质浓度,检测结果不受新旧汗液混合的干扰,准确性高。(The invention discloses a wearable sweat sensor device for continuously detecting electrolyte concentration in real time. The sensor device includes: a sweat channel, one end opening of which is arranged near the skin surface and is used for continuously inputting sweat generated on the skin surface; the detection mechanism is used for detecting sweat flowing through a sweat channel so as to acquire electrolyte concentration information in the sweat; the sweat absorbing mechanism is matched with the opening at the other end of the sweat channel far away from the skin and is used for continuously absorbing sweat output by the sweat channel so as to enable sweat generated on the surface of the skin to continuously pass through the sweat channel. The wearable sweat sensor device can continuously detect the concentration of sweat electrolyte in real time, the detection result is not interfered by the mixing of new and old sweat, and the accuracy is high.)

1. A wearable sweat sensor device for real-time continuous detection of electrolyte concentration, comprising:

a sweat channel, one end opening of which is arranged near the skin surface and is used for continuously inputting sweat generated on the skin surface;

the detection mechanism is used for detecting sweat flowing through a sweat channel so as to acquire electrolyte concentration information in the sweat;

the sweat absorbing mechanism is matched with the opening at the other end of the sweat channel far away from the skin and is used for continuously absorbing sweat output by the sweat channel so as to enable sweat generated on the surface of the skin to continuously pass through the sweat channel.

2. The wearable sweat sensor device of claim 1 where the inner wall of the sweat channel is hydrophobic in nature.

3. The wearable sweat sensor device of claim 1 where the detection mechanism includes at least one pair of electrodes, each pair of electrodes being at least partially exposed within the sweat channel and capable of contacting sweat flowing through the sweat channel.

4. The wearable sweat sensor device of claim 3 where the local surface of the electrodes exposed within the sweat channel is hydrophobic.

5. The wearable sweat sensor device for real-time continuous detection of electrolyte concentration of claim 1 further comprising a sweat reservoir in open communication with one end of the sweat channel for collection of sweat generated from a skin surface.

6. The wearable sweat sensor device of claim 1, wherein the wearable sweat sensor device comprises a chamber layer, an electrode layer, and a sweat absorbing mechanism sequentially disposed in a direction away from the skin surface, the sweat absorbing mechanism comprises a sweat absorbing layer, the chamber layer comprises a sweat storage chamber, the sweat channel penetrates the electrode layer in the direction away from the skin surface, and at least one pair of the electrodes is disposed in the electrode layer.

7. The wearable sweat sensor device of claim 6 where the sweat channel includes at least one first through hole distributed within the electrode layer, the at least one first through hole being in communication with the sweat storage chamber; preferably, the inner wall of the first through hole is hydrophobic in nature.

8. The wearable sweat sensor device of claim 7 where the sweat storage chamber includes a second through hole distributed within the chamber layer, the second through hole being in communication with the at least one first through hole; preferably, the inner wall of the second through hole is hydrophobic in nature.

9. The wearable sweat sensor device of claim 6 where the local surface of the electrodes exposed within the sweat channel is hydrophobic.

10. The wearable sweat sensor device of claim 6 where the electrode layer includes a first electrode and a second electrode stacked in a direction away from the skin surface; preferably, the first electrode and the second electrode are conductive electrodes.

11. The wearable sweat sensor apparatus for real-time continuous detection of electrolyte concentration according to claim 6, wherein the electrodes are electrically connected to a solution conductivity detection device.

12. The wearable sweat sensor device of claim 6 where there is also a porous hydrophobic layer between the electrode layer and the sweat absorbing layer, the porous hydrophobic layer connected to the electrode layer by a first adhesive layer; and/or the chamber layer is connected with the electrode layer through a second adhesive layer.

13. A wearable sweat sensor device for real-time and continuous detection of electrolyte concentration is characterized by comprising a chamber layer, an electrode layer, a porous hydrophobic layer and a sweat absorbing layer which are sequentially arranged along the direction far away from the surface of skin; a sweat storage chamber is arranged in the cavity layer, a sweat channel is arranged in the electrode layer, the sweat storage chamber is communicated with one end of the sweat channel, and the other end of the sweat channel is communicated with the sweat absorbing layer through the porous hydrophobic layer; the electrode layer includes at least one pair of electrodes, each pair of electrodes being at least partially exposed within the sweat channel and capable of being in contact with sweat flowing through the sweat channel.

14. The wearable sweat sensor device of claim 13 where the sweat channel extends through the electrode layer in a direction away from the skin surface.

15. A method for continuously measuring sweat electrolyte concentration in real time, comprising:

placing the wearable sweat sensor device of any one of claims 1-12 on a selected skin surface area;

continuously collecting and analyzing the conductance signal generated by the wearable sweat sensor device to enable detection of sweat electrolyte concentration in the selected skin surface area.

Technical Field

The invention belongs to the technical field of wearable equipment, and particularly relates to a wearable sweat sensor device for continuously detecting electrolyte concentration in real time.

Background

When people work in a high-temperature environment and do sports, a large amount of body fluid can be lost due to thermoregulation sweating, if reasonable hydration supplement is not carried out in time, the working and sports durability can be damaged, and along with the change of various physiological functions, the life health of people can be threatened in severe cases. The normal range of sweat electrolyte total concentration is 50-200 mmol/kg, the average concentration is 117mmol/kg for men and 134mmol/kg for women. The sweat loses water and electrolytes under heat and movement, so that electrolyte of a human body is disordered, hyponatremia, hypernatremia, hypokalemia, hyperkalemia and the like occur, and symptoms such as weakness, muscle ache, nausea, vomiting, coma and the like occur to different degrees, and even death occurs. Therefore, accurate monitoring of human electrolyte levels is of great significance in assessing health conditions.

In clinical studies, the indicators for detecting and evaluating the electrolyte level of human body mainly include weight change (water loss), plasma osmolality, plasma sodium ion concentration, etc. Although the indexes can relatively accurately judge the loss state of the electrolyte in the human body, the current detection method for the electrolyte level in the human body has the problems of incapability of continuously monitoring the electrolyte level in real time for a long time (invasiveness), time-consuming and expensive detection, high professional demand and the like, so that the electrolyte level monitoring is difficult to widely study in the fields of sports, military, rehabilitation and the like.

However, the application of traditional sweat research to human electrolyte level monitoring presents a number of problems and challenges, including: (1) the traditional sweat collection process is complex and time-consuming, no standardized equipment and quantitative indexes exist, and sweat is often polluted, volatilized, mixed with new and old sweat in a crossed manner, reabsorbed and the like; (2) the laboratory detection equipment needs a large amount of sweat; (3) non-real time continuous collection of sweat samples, etc. The problems not only affect the characteristics of non-invasion and real-time continuity of sweat, but also severely limit the deep research on the relationship between sweat and dehydration. Thus, wearable sweat sensors provide new opportunities for real-time continuous long-term monitoring of human electrolyte levels. Through monitoring the total concentration of sweat electrolytes, the method is expected to directly evaluate and early warn the loss state of the electrolytes in real time, and promotes the development of wearable equipment in the fields of individual health management and medical monitoring.

At present, the detection principle of the wearable sweat sensing technology on electrolyte ions is mainly based on an electrochemical ion selective electrode method, which is often limited by the problems of instability of electrode potential, additional pretreatment process, calibration operation and the like, and development of a sensing analysis means which is simple in preparation, high in stability and free of calibration is urgently needed in practical application.

Disclosure of Invention

The invention mainly aims to provide a wearable sweat sensor device for continuously detecting the concentration of electrolyte in real time, which solves the problems in the prior art.

In order to achieve the purpose, the technical scheme adopted by the invention comprises the following steps:

an embodiment of the present invention provides a wearable sweat sensor device for continuously detecting electrolyte concentration in real time, which includes:

a sweat channel, one end opening of which is arranged near the skin surface and is used for continuously inputting sweat generated on the skin surface;

the detection mechanism is used for detecting sweat flowing through a sweat channel so as to acquire electrolyte concentration information in the sweat;

the sweat absorbing mechanism is matched with the opening at the other end of the sweat channel far away from the skin and is used for continuously absorbing sweat output by the sweat channel so as to enable sweat generated on the surface of the skin to continuously pass through the sweat channel.

Further, the interior walls of the sweat channels are hydrophobic in nature.

Further, the detection mechanism includes at least one pair of electrodes, each pair of electrodes being at least partially exposed within the sweat pathway and capable of contacting sweat flowing through the sweat pathway.

Further, the local surface of the electrode exposed in the sweat channel is hydrophobic.

The embodiment of the invention also provides a wearable sweat sensor device for continuously detecting the electrolyte concentration in real time, which comprises a cavity layer, an electrode layer, a porous hydrophobic layer and a sweat absorbing layer, wherein the cavity layer, the electrode layer, the porous hydrophobic layer and the sweat absorbing layer are sequentially arranged in the direction away from the surface of the skin; a sweat storage chamber is arranged in the cavity layer, a sweat channel is arranged in the electrode layer, the sweat storage chamber is communicated with one end of the sweat channel, and the other end of the sweat channel is communicated with the sweat absorbing layer through the porous hydrophobic layer; the electrode layer includes at least one pair of electrodes, each pair of electrodes being at least partially exposed within the sweat channel and capable of being in contact with sweat flowing through the sweat channel.

The embodiment of the invention also provides a method for continuously detecting the electrolyte concentration of sweat in real time, which comprises the following steps:

placing said wearable sweat sensor device on a selected skin surface area;

continuously collecting and analyzing the conductance signal generated by the wearable sweat sensor device to enable detection of sweat electrolyte concentration in the selected skin surface area.

Compared with the prior art, the wearable sweat sensor device for continuously detecting the electrolyte concentration in real time provided by the invention at least has the following beneficial effects:

(1) the wearable sweat sensor device that provides is through setting up the sweat passageway that the weak point is little to carry out the measuring of electrolyte concentration in the sweat passageway, the sweat sample volume is little, and the sweat after the measuring can be absorbed by sweat absorbing mechanism rapidly, can not have the sweat accumulation, can effectively avoid the mixture of new and old sweat, guarantees the accuracy and the real-time of test.

(2) The wearable sweat sensor device provided can realize real-time continuous detection of the concentration of sweat electrolytes through a real-time continuous conductance curve.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.

Fig. 1 is a schematic cross-sectional view of a wearable sweat sensor device for real-time continuous detection of electrolyte concentration attached to the skin surface, as provided in example 1 of the present invention;

FIG. 2 is a top view of a wearable sweat sensor device that continuously detects electrolyte concentration in real time as provided in example 1 of the present invention;

FIG. 3 is a schematic diagram of the overall structure of a wearable sweat sensor device for real-time continuous detection of electrolyte concentration, as provided in example 1 of the present invention;

FIG. 4 is a graph of conductance signal when a wearable sweat sensor device that continuously detects electrolyte concentration in real time as provided in example 1 of the present invention is tested on human skin;

FIG. 5 is a schematic cross-sectional view of a wearable sweat sensor device with real-time continuous electrolyte concentration detection attached to the skin surface, as provided in example 2 of the present invention;

FIG. 6 is a top view of a wearable sweat sensor device that continuously detects electrolyte concentration in real time as provided by example 2 of the present invention;

fig. 7 is a graph of conductance signal of a wearable sweat sensor device for real-time continuous detection of electrolyte concentration under microfluidic syringe pump test conditions, as provided in embodiments 1 or 2 of the present invention.

Reference numerals: 1-human skin sweating system; 11-epidermis of the skin; 12-peeling; 13-sweat; 14-sweat glands; 2-a flexible substrate; 21-a second via; 3-a second adhesive layer; 31-a third via; 41-bulk film; 421-a first electrically conductive electrode; 422-a second electrically conductive electrode; 43-a first via; 44-a first pin; 45-a second pin; 5-a first adhesive layer; 51-a fourth via; 6-a porous hydrophobic layer; 7-a sweat-absorbing layer; 8-sweat storage chamber.

Detailed Description

In view of the defects of the prior art, the inventor of the present invention has made extensive research and practice to propose the technical solution of the present invention. The technical solution, its implementation and principles, etc. will be further explained as follows.

An embodiment of the present invention provides a wearable sweat sensor device for continuously detecting electrolyte concentration in real time, which includes:

a sweat channel, one end opening of which is arranged near the skin surface and is used for continuously inputting sweat generated on the skin surface;

the detection mechanism is used for detecting sweat flowing through a sweat channel so as to acquire electrolyte concentration information in the sweat;

the sweat absorbing mechanism is matched with the opening at the other end of the sweat channel far away from the skin and is used for continuously absorbing sweat output by the sweat channel so as to enable sweat generated on the surface of the skin to continuously pass through the sweat channel.

Wherein the inner wall of the sweat pathway is hydrophobic in nature.

Further, the detection mechanism includes at least one pair of electrodes, each pair of electrodes being at least partially exposed within the sweat pathway and capable of contacting sweat flowing through the sweat pathway.

Wherein the partial surface of the electrode exposed in the sweat channel is hydrophobic.

Further, the wearable sweat sensor device further comprises a sweat storage chamber, which is communicated with one end opening of the sweat channel and is used for collecting sweat generated on the surface of the skin.

Specifically, wearable sweat sensor device includes the locular layer, electrode layer, the sweat absorbing mechanism that set gradually along the direction of keeping away from the skin surface, the sweat absorbing mechanism includes the sweat layer, the locular layer includes the sweat apotheca, the electrode layer is run through along the direction of keeping away from the skin surface to the sweat passageway, be equipped with at least a pair of in the electrode layer the electrode.

Further, the sweat channel includes at least one first through hole distributed within the electrode layer, the at least one first through hole being in communication with the sweat storage chamber. Wherein the inner wall of the first through hole is hydrophobic.

Preferably, the aperture of the first through hole is 0.1-1.5 mm.

Further, the electrode layer includes a first electrode and a second electrode which are stacked in a direction away from the skin surface.

In one embodiment, the electrode layer comprises a body membrane having at least one pair of first and second electrodes disposed on both upper and lower surfaces of the body membrane, and the second electrode is exposed to the sweat storage chamber.

In another embodiment, the first and second electrodes are distributed inside the bulk film.

Preferably, the thickness of the main film is 0.1-2 mm.

Preferably, the bulk film comprises a flexible insulating polymer film.

Preferably, the flexible insulating polymer is dimethyl siloxane, silicone rubber or thermoplastic polyester.

In one embodiment, the first and second electrodes are electrically conductive electrodes.

Preferably, the material of the conductive electrode is carbon nanotube, graphene, carbon black or carbon fiber.

In some cases, the material of the conductive electrode may also be a thin film electrode made of other materials such as metals for electrical conductivity test, such as gold, platinum, copper, etc., and having a certain thickness and width.

Preferably, the electrically conductive electrode is a thin film electrode.

Preferably, the thickness of the thin film electrode is 0.01-1 mm.

In one embodiment, the host film, the first electrode, and the second electrode may be directly prepared using a hydrophobic material.

In another embodiment, the hydrophobicity may be achieved by post-treatment, for example, the inner wall of the first through hole may be treated with a silane reagent after the first through hole is opened to achieve the hydrophobicity.

Further, the electrode is electrically connected with a solution conductivity detection device.

Further, the chamber layer includes a flexible substrate, and the sweat storage chamber includes a second through hole disposed on the flexible substrate, the second through hole being in communication with the first through hole on the electrode layer.

Preferably, the inner wall of the second through hole is hydrophobic.

Preferably, the aperture of the second through hole is 2-10 mm.

Further, the flexible substrate includes a flexible insulating polymer film.

Preferably, the thickness of the flexible insulating polymer film is 0.1-0.5 mm.

Preferably, the flexible polymer is a dimethyl siloxane, a silicone rubber or a thermoplastic polyester.

Furthermore, a porous hydrophobic layer is further arranged between the electrode layer and the sweat absorbing layer, the porous hydrophobic layer is connected with the electrode layer through a first bonding layer, and the chamber layer is connected with the electrode layer through a second bonding layer.

Preferably, the porous hydrophobic layer comprises a hydrophobic porous film, and the material of the hydrophobic porous film can be a filter screen, a porous fabric, a thermoplastic elastomer and the like.

In one embodiment, the polymeric material may be spun into a film to act as a hydrophobic layer.

Preferably, the thermoplastic polyurethane elastomer rubber is used for preparing the one-way sweat-permeable porous film as the hydrophobic layer through electrostatic spinning.

Preferably, the sweat-absorbent layer comprises a hydrophilic film.

In one embodiment, the garment itself may be used as the sweat absorbing layer.

Preferably, the sweat absorbing layer is made of breathable sweat-permeable athletic close-fitting clothes, wristbands, palms, elbows, sweat absorbing belts, sweat absorbing patches and the like.

In one embodiment, the first adhesive layer and the second adhesive layer are adhesive films, and comprise ultrathin double-sided adhesive with fixed thickness, prepolymer of viscoelastic polymer and the like.

Preferably, the thickness of the adhesive film is 0.01-0.05 mm.

Furthermore, at least one third through hole matched with the first through hole of the electrode layer is formed in the first bonding layer, and the third through hole is communicated with the first through hole.

Further, a fourth through hole is formed in the second adhesive layer and communicated with the second through hole;

preferably, the aperture of the fourth through hole is 2-10 mm.

In one embodiment, a third through hole corresponding to the first through hole on the electrode layer in position and size can be prepared on the first adhesive layer by laser cutting, template or mechanical punching, so that sweat can flow through the third through hole and be continuously absorbed by the sweat absorbing layer in real time.

Preferably, the inner walls of the third through hole and the fourth through hole are hydrophobic.

According to the wearable sweat sensor device, the short vertical sweat channel is designed, the conductance value is detected in the sweat channel, the sweat sample volume is very small, the sweat sample can be quickly absorbed by the sweat absorbing layer after detection, no sweat accumulation exists, mixing of new sweat and old sweat can be effectively avoided, and the accuracy and the real-time performance of testing are guaranteed. Meanwhile, the short sweat channel can effectively avoid the adsorption of salt ions in the sweat on the inner wall of the channel.

The wearable sweat sensor device provided by the invention can be wrapped and fixed on the skin surface through the strip made of elastic fabric and elastomer materials, and can also be integrated and compatible with fabrics such as sports close-fitting clothes, wristbands, palms, elbows, sweat absorbing belts, sweat absorbing pastes and the like.

The embodiment of the invention also provides a method for continuously detecting the electrolyte concentration of sweat in real time, which comprises the following steps:

placing said wearable sweat sensor device on a selected skin surface area;

continuously collecting and analyzing the conductance signal generated by the wearable sweat sensor device to enable detection of sweat electrolyte concentration in the selected skin surface area.

Specifically, the electrode pins of the electrode layer may be connected to an instrument or wearable miniaturized detection device for detecting solution conductance, and necessary flexible lead interface design and electrical insulation packaging processing may be performed to obtain the conductance signal of the wearable sweat sensor device in real time, form a conductance curve, and obtain real-time and continuous total electrolyte concentration information through conductance curve analysis.

The conductance curve is continuously changed, the signal of the conductance curve begins to mutate to represent that the human skin begins to secrete sweat, and the value of the conductance curve is positively correlated with the real-time electrolyte concentration of the sweat.

Therefore, the wearable sweat sensor device provided by the invention can obtain a real-time conductance curve, namely information of real-time sweat electrolyte concentration change can be obtained, and the detection result is not interfered by mixing of new sweat and old sweat, so that the accuracy is high.

It should be noted that the wearable sweat sensor device of the present invention may also be used for electrolyte concentration testing of other solutions, for example, the liquid to be tested may be pumped into the memory chamber of the wearable sweat sensor device by a micro-fluid injection pump, and then the electrolyte concentration information of the tested liquid is analyzed according to the same principle, i.e., the obtained conductance curve.

The technical solutions in the embodiments of the present invention will be described in detail below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.

Example 1

Referring to fig. 1 and 2, a wearable sweat sensor device for real-time and continuous detection of electrolyte concentration according to the present embodiment includes: the flexible substrate 2, and the second bonding layer 3, the electrode layer 4, the first bonding 5, the porous hydrophobic layer 6 and the sweat absorbing layer 7 which are sequentially arranged on the flexible substrate 2.

The flexible substrate 2 is fixedly connected with the electrode layer 4 through the second bonding layer 3, and the electrode layer 4 is fixedly connected with the porous hydrophobic layer 6 through the first bonding layer 5.

Specifically, the flexible substrate 2 and the second adhesive layer 3 are respectively provided with a second through hole 21 and a fourth through hole 31 with the same diameter, and the second through hole 21 is communicated with the fourth through hole 41 to form the sweat storage chamber 8.

Specifically, the electrode layer 4 is composed of a main body film 41, and a second conductance electrode 422 and a first conductance electrode 421 respectively distributed on the upper surface and the lower surface of the main body film 41, and a plurality of first through holes 43 are formed in the electrode layer 4 to form a sweat channel, and the plurality of first through holes 43 continuously penetrate through the second conductance electrode 422, the main body film 41 and the first conductance electrode 421 and are communicated with the sweat storage chamber 8.

Specifically, the thickness of the main thin film 41 is 0.1 to 2mm, the thickness of the first conductive electrode 421 and the second conductive electrode 422 is 0.01 to 1mm, and the aperture of the first through hole is 0.1 to 1.5 mm.

Wherein the first conductance electrode 421 is exposed in the sweat storage chamber 8, and the second conductance electrode 422 is in contact with the porous hydrophobic layer 6 via the first adhesive layer 5.

Specifically, a plurality of third through holes 51 corresponding to the first through holes 43 on the electrode layer 4 in position and having the same size are formed in the first adhesive layer 5, and the third through holes 51 are communicated with the first through holes 43, so that sweat detected in the first through holes 43 passes through the third through holes and the porous hydrophobic layer 6 and then is continuously absorbed by the sweat absorbing layer 7 in real time, and the problem that the accuracy of a test result is interfered due to mixing of new and old sweat is solved.

When the wearable sweat sensor device is used specifically, the wearable sweat sensor device in the embodiment is attached to the skin epidermis 11, and sweat 13 has certain pressure when being secreted from sweat glands 14, and the maximum pressure can reach 70000Nm-2Sufficient to pump sweat 13 into first through hole 43; when sweat passes through the first through hole 43 and accumulates upwards, the sweat contacts the first conductance electrode 421 and the second conductance electrode 422 which are exposed to the inner wall of the first through hole 43, and the first conductance electrode 421. The second conductance electrode 422 is connected to a conductance detection device or a wearable miniaturized detection device through the exposed first pin 44 and the exposed second pin 45 (as shown in fig. 3, the conductance detection device is not shown) to obtain a conductance signal of the wearable sweat sensor device in real time, the conductance detection device records a continuous conductance value of the sweat 13 in real time to form a real-time continuous conductance curve as shown in fig. 4, when the conductance curve signal begins to change suddenly, the sweat secretion of the human skin is represented, and the height or amplitude of the continuous conductance curve is positively correlated to the real-time total concentration of sweat electrolytes in the first through hole 43. Therefore, real-time continuous sweat electrolyte concentration change can be obtained through a real-time continuous conductance curve.

The lead wire connected with the electrode pin and the conductivity detection instrument can use flexible conductive carbon cloth, fiber lead wire and the like and is embedded in devices such as fabrics and the like.

Example 2

Referring to fig. 5 and 6, another wearable sweat sensor device for real-time continuous detection of electrolyte concentration is provided in this embodiment, which is substantially the same as the wearable sweat sensor device in embodiment 1, except that first conductance electrode 421 and second conductance electrode 422 are embedded inside body membrane 41, i.e. first conductance electrode 421 is not directly exposed to sweat storage chamber 8, and second conductance electrode 422 is not in contact with porous hydrophobic layer 6.

Through the wearable sweat sensor device in the embodiment, a real-time conductance change curve can be obtained, and then the sweat electrolyte concentration information is obtained.

The present embodiment also provides a method for preparing the electrode layer 4, which includes:

firstly preparing a first main film, preparing a first conductive electrode 421 on the first main film by screen printing or the like, then preparing a second main film on the first main film and the first conductive electrode 421, preparing a second conductive electrode 422 on the second main film by screen printing or the like, overlapping the main parts of the first conductive electrode 421 and the second conductive electrode 422 up and down, finally preparing a third main film on the second main film and the second conductive electrode 422, and embedding the first conductive electrode 421 and the second conductive electrode 422 in the main film 41.

It should be noted that when the wearable sweat sensor device in embodiment 1 or embodiment 2 is used to test the electrolyte concentration of other liquids, the liquid to be tested is continuously pumped into the sweat storage chamber 8 of the wearable sweat sensor device by the micro-fluid injection pump, and then the electrolyte concentration information of the tested liquid can be analyzed by the obtained real-time continuous conductance curve (as shown in fig. 7).

In summary, the wearable sweat sensor device provided by the invention can obtain real-time and continuous electrolyte concentration change conditions through a real-time and continuous conductance curve; meanwhile, sweat after detection can be rapidly absorbed by the upper sweat absorbing mechanism, and the sweat absorption device has the advantages of being not mixed by new and old sweat to interfere with accuracy. The invention can help to evaluate and early warn the metabolic change of the human body caused by a large amount of sweating during sports or high-temperature special operation, thereby reducing the health risk.

As used herein, the term "include" and its variants mean open-ended terms in the sense of "including, but not limited to. The terms "based on," based on, "and the like mean" based at least in part on, "" based at least in part on. The terms "first," "second," and the like may refer to different or the same object.

It should be understood that the technical solution of the present invention is not limited to the above-mentioned specific embodiments, and all technical modifications made according to the technical solution of the present invention fall within the protection scope of the present invention without departing from the spirit of the present invention and the protection scope of the claims.

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