Detection system integrated with dyeing function and used for microscopic examination

文档序号:47339 发布日期:2021-09-28 浏览:40次 中文

阅读说明:本技术 一种集成有染色功能的显微镜镜检的检测系统 (Detection system integrated with dyeing function and used for microscopic examination ) 是由 赵国军 张嘉桐 刘律文 张帅 李昂 陈健 于 2021-06-26 设计创作,主要内容包括:本发明公开了一种集成有染色功能的显微镜镜检的检测系统,包括显机架、载物台、目镜和摄像机组、物镜组、染液试剂进样管、检验样本进样管、洗脱液进样管、出样管、未染色计数室、染色计数室、载玻片;所述机架上安装有物镜组,所述物镜组的正上方安装有目镜和摄像机组,所述物镜组的正下方安装有载物台,所述载物台的上方设置有未染色计数室、染色计数室和载玻片、染液试剂进样管、检验样本进样管、洗脱液进样管、出样管,所述染液试剂进样管、检验样本进样管、洗脱液进样管安装在载物台左端,所述出样管安装在载物台右端。本发明实现了临床检验工作中的染色和镜检的一体化和全自动化,提高工作的准确度和工作效率,确保染色的质量和检验效果。(The invention discloses a detection system integrated with a dyeing function for microscopic examination, which comprises a display rack, an object stage, an ocular, a camera set, an objective group, a dye solution reagent sample inlet pipe, a test sample inlet pipe, an eluent sample inlet pipe, a sample outlet pipe, an undyed counting chamber, a dyed counting chamber and a glass slide, wherein the object stage is arranged on the object stage; install objective group in the frame, install eyepiece and camera group directly over objective group, the objective group installs the objective table under, the top of objective table is provided with unstained counting chamber, dyed counting chamber and slide glass, dye liquor reagent sample inlet pipe, inspection sample inlet pipe, eluant sample inlet pipe, goes out the appearance pipe, dye liquor reagent sample inlet pipe, inspection sample inlet pipe, eluant sample inlet pipe install at the objective table left end, it installs at the objective table right-hand member to go out the appearance pipe. The invention realizes the integration and full automation of dyeing and microscopic examination in clinical examination work, improves the working accuracy and working efficiency, and ensures the dyeing quality and the examination effect.)

1. A detection system integrated with a staining function for microscopic examination is characterized by comprising a microscope set and a staining set, wherein the microscope set comprises a rack, an objective table, an ocular lens, a camera set and an objective lens set; the staining group comprises a staining solution reagent sample inlet pipe, a test sample inlet pipe, an eluent sample inlet pipe, a sample outlet pipe, an unstained counting chamber, a staining counting chamber and a glass slide; install objective group in the frame, install eyepiece and camera group directly over objective group, the objective group installs the objective table under, the top of objective table is provided with unstained counting chamber, dyed counting chamber and slide glass, still be provided with dye liquor reagent sample inlet pipe, inspection sample inlet pipe, eluant sample inlet pipe, play appearance pipe on the objective table, dye liquor reagent sample inlet pipe, inspection sample inlet pipe, eluant sample inlet pipe install at the objective table left end, it installs at the objective table right-hand member to go out the appearance pipe.

2. The system of claim 1, wherein the objective lens group comprises two or more objective lenses with different optical lengths, and the rotatable switching objective lens is mounted on the frame.

3. The microscope microscopic examination detection system integrated with dyeing function as claimed in claim 1, wherein said stage can be moved horizontally on the frame to adjust the photographing position.

4. The microscope microscopic detection system integrated with the staining function as claimed in claim 1, wherein the staining group performs automatic staining, automatic elution and automatic sample output on the sample by setting different staining parameters or staining modes for the system.

5. The microscope microscopic examination detection system integrated with the dyeing function as claimed in claim 1, wherein the eyepiece and the camera set are equipped with high-pixel cameras, and are compatible with high-pixel cameras of different manufacturers, and the microscope set, the dyeing set and the objective table capable of automatically adjusting the position are integrated, so that the microscope microscopic examination detection system has the dyeing function, automation and intellectualization are realized, and the accuracy of microscopic examination is greatly improved.

6. The microscope inspection system according to claim 1, wherein a collecting mirror is fixed in the middle of the upper end of the rack, a light gathering adjusting switch is embedded in the side surface of the rack, a storage battery is fixed in the rack, and the storage battery and the light gathering adjusting switch are respectively connected with the collecting mirror through connecting lines.

7. The microscope microscopic examination detection system integrated with the dyeing function as claimed in claim 1, wherein four corners of the bottom of the rack are fixed with buffer support legs, the buffer support legs are provided with support sleeves, the upper ends of the support sleeves are fixedly connected with the bottom of the rack, the lower ends of the support sleeves are provided with support seats, and springs are arranged between the upper ends of the support seats and the upper ends of the interiors of the support sleeves.

8. The microscope microscopic examination detection system integrated with the dyeing function as claimed in claim 7, wherein the upper end of the support is provided with a limit ring, and the limit ring is sleeved on the inner side of the support sleeve.

9. The microscope microscopic examination detection system integrated with the staining function as claimed in claim 7, wherein a cushion pad is fixedly connected to the bottom of the support, and the bottom of the cushion pad is provided with anti-skid lines.

10. The microscope microscopic detection system integrated with the staining function as claimed in claim 1, wherein the ocular lens and the camera set of the camera set are located on the upper inner side of the ocular lens and on the upper end of the objective lens set.

Technical Field

The invention relates to the technical field of microscope microscopic detection systems, in particular to a microscope microscopic detection system integrated with a dyeing function.

Background

In order to observe and study visible components such as bacteria, eggs, and cells in clinical tests clearly and accurately, the visible components are colored with a dye, and information such as the size and morphological structure of the colored components is observed with a microscope. Factors such as a dyeing method, dyeing time, a dyeing operation technology and the like can directly influence the quality of dyeing, so that the diagnosis accuracy in clinical examination is influenced. Most dyeing works are manual operation at present, and a lot of problems which cannot be avoided are generated in long-term manual dyeing works, for example, the dyeing work flow is not standardized, the dyeing quality is different, the dyeing work efficiency is not high, and the pollution and the injury to the body of an operator are caused by improper use of a dyeing solution. Dyeing instruments on the market at present also face the puzzles of not high accuracy, operation flexibility is low, degree of automation is not high etc..

In the routine clinical examination work of hospitals, the staining and the microscopic examination are separately operated, so that the method is not limited to the problems of the staining work, but also limited by the microscopic examination analysis system such as aging of the system, low shooting precision, low automation degree and the like, and the accuracy and the examination efficiency of the examination cannot be fundamentally improved.

Disclosure of Invention

Aiming at the defects of the prior art, the invention provides a detection system integrated with a microscope examination with a staining function, which comprises a microscope group and a staining group, wherein the microscope group comprises a rack, an objective table, an ocular lens, a camera group and an objective lens group; the staining group comprises a staining solution reagent sample inlet pipe, a test sample inlet pipe, an eluent sample inlet pipe, a sample outlet pipe, an unstained counting chamber, a staining counting chamber and a glass slide; install objective group in the frame, install eyepiece and camera group directly over objective group, the objective group installs the objective table under, the top of objective table is provided with unstained counting chamber, dyed counting chamber and slide glass, still be provided with dye liquor reagent sample inlet pipe, inspection sample inlet pipe, eluant sample inlet pipe, play appearance pipe on the objective table, dye liquor reagent sample inlet pipe, inspection sample inlet pipe, eluant sample inlet pipe install at the objective table left end, it installs at the objective table right-hand member to go out the appearance pipe.

Preferably, the objective lens group includes more than two objective lenses with different optical lengths, and the rotatable switching objective lens is mounted on the frame.

Preferably, the object stage can move horizontally on the frame to adjust the shooting position.

Preferably, the staining group sets different staining parameters or staining modes for the system to complete automatic staining, automatic elution and automatic sample discharge of the sample.

Preferably, the eyepiece is equipped with high pixel camera with the group of taking a picture in the camera group, can compatible different producers' high pixel camera, and with microscope group, dyeing group and can the automatic position regulation the objective table integration, makes the detecting system that the microscope mirror was examined possess the dyeing function to realize automatic and intelligent, promoted the accurate precision of mirror examination by a wide margin.

Preferably, a collecting mirror is fixed in the middle of the upper end of the rack, a condensation regulating switch is embedded in the side face of the rack, a storage battery is fixed inside the rack, and the storage battery and the condensation regulating switch are respectively connected with the collecting mirror through a connecting circuit.

Preferably, four corners of the bottom of the rack are respectively fixed with a buffer support leg, each buffer support leg is provided with a support sleeve, the upper end of each support sleeve is fixedly connected with the bottom of the rack, the lower end of each support sleeve is provided with a support, and a spring is arranged between the upper end of each support and the upper end inside each support sleeve.

Preferably, the upper end of the support is provided with a limiting ring, and the limiting ring is sleeved on the inner side of the support sleeve.

Preferably, the bottom of the support is fixedly connected with a cushion pad, and the bottom of the cushion pad is provided with anti-skid lines.

Preferably, the eyepiece and the camera set in the camera set are positioned on the upper side inside the eyepiece and positioned right above the objective lens set.

Compared with the prior art, the invention has the beneficial effects that:

1. the invention can convert the objective lenses with different optical lengths according to the physicochemical properties of a sample to be detected, adjust the light and the shooting angle, is provided with the latest high-pixel camera on the group surface of the camera, can be compatible with the cameras of different manufacturers, is matched with a microscopic examination system on the configuration of the objective table, fully automatically adjusts the shooting position, and greatly improves the detection accuracy.

2. The invention solves the problems of non-standardization of dyeing work and larger result in-out in actual clinical work, realizes the integration and full automation of dyeing and microscopic examination in clinical examination work, improves the working accuracy and working efficiency, and ensures the dyeing quality and the examination effect.

3. The microscope group and the staining group are integrated, microscopic examination can be performed after full-automatic staining, and the problem that the working accuracy is low due to the fact that the staining group and the microscope group cannot be integrated in the current market is solved.

4. The invention can provide enough illumination for the objective table through the condenser lens, and can adjust the light intensity through the condensation adjusting switch; can play the cushioning effect through buffering stabilizer blade, avoid causing the vibration to damage microscope, support the spacing ring of cover inboard and can lead to spacingly to the lower extreme support, avoid the slope, can avoid skidding through blotter and anti-skidding line.

Drawings

FIG. 1 is a schematic structural diagram of the present invention.

Fig. 2 is a schematic structural diagram of the rack of the present invention.

Fig. 3 is a schematic structural view of the buffering leg of the present invention.

In the figure: 1-a staining reagent sampling tube; 2-inspecting the sample inlet tube; 3-eluent sample tube; 4-ocular and camera set; 5-an objective lens group; 6-unstained counting chamber; 7-staining counting chamber; 8-a sample outlet pipe; 9-an object stage; 10-a frame; 11-a condenser lens; 12-a spotlight adjusting switch; 13-a buffer foot; 14-a support sleeve; 15-a support; 16-a spring; 17-a stop collar; 18-buffer pad.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

As shown in fig. 1, a detection system integrated with a microscope examination of a staining function comprises a microscope set and a staining set, wherein the microscope set comprises a frame 10, an objective table 9, an ocular lens, a camera set 4 and an objective lens set 5, the objective lens set 5 comprises more than two objective lenses with different optical lengths, and the camera sets in the ocular lens and the camera set 4 are provided with high-pixel cameras and can be compatible with the high-pixel cameras of different manufacturers; the staining group comprises a staining solution reagent sample inlet pipe 1, a test sample inlet pipe 2, an eluent sample inlet pipe 3, a sample outlet pipe 8, an unstained counting chamber 6, a staining counting chamber 7 and a glass slide; install objective group 5 in the frame 10, the rotatable switching of objective on the objective group 5, eyepiece and camera set 4 are installed directly over the objective group 5, objective group 5 installs objective table 9 under, objective table 9 can adjust the shooting position in frame 10 upper horizontal migration, objective table 9's top is provided with unstained counting chamber 6, dyed counting chamber 7 and slide glass, still be provided with dye liquor reagent sample inlet pipe 1 on the objective table 9, test sample inlet pipe 2, eluant sample inlet pipe 3, play appearance pipe 8, dye liquor reagent sample inlet pipe 1, test sample inlet pipe 2, eluant sample inlet pipe 3 install at objective table 9 left end, it installs at objective table 9 right-hand member to go out appearance pipe 8. Four corners of the bottom of the frame 10 are fixed with buffer support legs 13.

Specifically, under the dyeing and elution settings of the system, samples are subjected to dyeing and elution in different reagents and different steps, firstly, a sample inlet pipe 2 is used for conveying a test sample to an undyed counting chamber 6 and a dyed counting chamber 7 respectively, then, a dye solution inlet pipe 1 is used for conveying dye solution for dyeing, then, an eluent inlet pipe 3 is used for conveying eluent for elution, after dyeing, an ocular lens and a camera group 4 are used for photographing, identifying and diagnosing, and after identifying and diagnosing, all liquid is output through a sample outlet pipe 8.

Specifically, the lens of the camera in the eyepiece and camera group 4 and the objective lenses with different optical lengths in the objective lens group 5 are switched and combined, and are focused on the mixed liquid of the glass slide on the objective table 9, the unstained counting chamber 6 and the stained counting chamber 7, and the objective lenses with different optical lengths are switched to shoot the target objects in the glass slide, the unstained counting chamber 6 and the stained counting chamber 6, so that the integration and full automation of staining and microscopic examination in the clinical examination work are realized, the working accuracy and working efficiency are improved, and the staining quality and the examination effect are ensured. The ocular and the camera set in the camera set 4 are positioned at the upper side of the inside of the ocular and are positioned right above the objective set.

Specifically, a collecting mirror 11 is fixed in the middle of the upper end of the rack 10, a condensation adjusting switch 12 is embedded in the side face of the rack 10, a storage battery is fixed inside the rack 10, and the storage battery and the condensation adjusting switch are respectively connected with the collecting mirror through a connecting circuit. Enough illumination can be provided for the objective table through the condensing lens, and the light intensity can be adjusted through the condensing adjusting switch.

As shown in fig. 2, the buffer leg 13 in the embodiment of the present invention is provided with a support sleeve 14, an upper end of the support sleeve 14 is fixedly connected with the bottom of the rack 10, a support 15 is provided at a lower end of the support sleeve 14, and a spring is provided between an upper end of the support 15 and an inner upper end of the support sleeve. Can play the cushioning effect through buffering stabilizer blade, avoid causing the vibration damage to the microscope.

Specifically, the upper end of the support 15 is provided with a limit ring 17, and the limit ring 17 is sleeved on the inner side of the support sleeve 14. The limiting ring at the inner side of the supporting sleeve can guide and limit the lower end support to avoid inclination.

Specifically, a cushion pad 18 is fixedly connected to the bottom of the support 15, and anti-skid lines are formed at the bottom of the cushion pad 18. The cushion pad and the anti-slip lines can avoid slipping.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

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